NO2716304T3 - - Google Patents
Info
- Publication number
- NO2716304T3 NO2716304T3 NO12790050A NO12790050A NO2716304T3 NO 2716304 T3 NO2716304 T3 NO 2716304T3 NO 12790050 A NO12790050 A NO 12790050A NO 12790050 A NO12790050 A NO 12790050A NO 2716304 T3 NO2716304 T3 NO 2716304T3
- Authority
- NO
- Norway
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
- A61K31/7105—Natural ribonucleic acids, i.e. containing only riboses attached to adenine, guanine, cytosine or uracil and having 3'-5' phosphodiester links
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
- C12N15/1137—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against enzymes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
- A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers with substantial amounts of non-phosphatidyl, i.e. non-acylglycerophosphate, surfactants as bilayer-forming substances, e.g. cationic lipids
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/14—Type of nucleic acid interfering N.A.
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2320/00—Applications; Uses
- C12N2320/30—Special therapeutic applications
- C12N2320/31—Combination therapy
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2320/00—Applications; Uses
- C12N2320/30—Special therapeutic applications
- C12N2320/32—Special delivery means, e.g. tissue-specific
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Virology (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2011114946 | 2011-05-23 | ||
PCT/JP2012/063082 WO2012161196A1 (ja) | 2011-05-23 | 2012-05-22 | チミジル酸合成酵素に対するshRNA分子を含むリポソームおよびその用途 |
Publications (1)
Publication Number | Publication Date |
---|---|
NO2716304T3 true NO2716304T3 (zh) | 2018-03-10 |
Family
ID=47217272
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO12790050A NO2716304T3 (zh) | 2011-05-23 | 2012-05-22 |
Country Status (14)
Country | Link |
---|---|
US (1) | US20120301537A1 (zh) |
EP (1) | EP2716304B1 (zh) |
JP (1) | JP5941460B2 (zh) |
CN (1) | CN103561775B (zh) |
DK (1) | DK2716304T3 (zh) |
ES (1) | ES2653923T3 (zh) |
HK (1) | HK1190325A1 (zh) |
HR (1) | HRP20171919T1 (zh) |
HU (1) | HUE037803T2 (zh) |
NO (1) | NO2716304T3 (zh) |
PL (1) | PL2716304T3 (zh) |
PT (1) | PT2716304T (zh) |
TW (1) | TWI442927B (zh) |
WO (1) | WO2012161196A1 (zh) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9693957B2 (en) | 2011-07-08 | 2017-07-04 | The University Of North Carolina At Chapel Hill | Metal bisphosphonate nanoparticles for anti-cancer therapy and imaging and for treating bone disorders |
US20140255471A1 (en) | 2013-03-11 | 2014-09-11 | Wake Forest University Health Sciences | Method of treating brain tumors |
HUE040425T2 (hu) | 2013-04-30 | 2019-03-28 | Delta Fly Pharma Inc | Liposzóma topikális adagoláshoz és alkalmazása |
JP6590802B2 (ja) * | 2013-11-06 | 2019-10-16 | ザ ユニバーシティ オブ シカゴThe University Of Chicago | 化学療法用薬剤、核酸及び光増感剤の送達又は共送達のためのナノスケール輸送体 |
AU2014384269A1 (en) * | 2014-02-26 | 2016-09-08 | Ethris Gmbh | Compositions for gastrointestinal administration of RNA |
WO2016068160A1 (ja) * | 2014-10-30 | 2016-05-06 | Delta-Fly Pharma株式会社 | 局所投与用リポプレックスの新規製造方法及び該リポプレックスを使用する抗腫瘍剤 |
CN109310702A (zh) | 2016-05-20 | 2019-02-05 | 芝加哥大学 | 用于化学疗法、靶向疗法、光动力疗法、免疫疗法和它们的任何组合的纳米颗粒 |
JP7232530B2 (ja) * | 2017-01-18 | 2023-03-03 | テマセク・ライフ・サイエンシーズ・ラボラトリー・リミテッド | 超安定リポソームによる有糸分裂細胞の標的化の増加 |
WO2019012107A1 (en) * | 2017-07-13 | 2019-01-17 | Danmarks Tekniske Universitet | CATIONIC LIPOSOMES |
CN111194232B (zh) | 2017-08-02 | 2023-01-31 | 芝加哥大学 | 纳米级金属有机层和金属有机纳米片 |
JP6297737B1 (ja) | 2017-09-25 | 2018-03-20 | ジェイ−ネットワーク,インコーポレイテッド | 正に帯電した荷電ニオソームの調製方法及び荷電ニオソーム |
CN114557964B (zh) * | 2022-03-17 | 2024-03-12 | 西安艾领克生物科技有限公司 | 一种可载rna的阳离子梭型柔性脂质体及其制备方法和应用 |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8202846B2 (en) * | 2000-03-16 | 2012-06-19 | Cold Spring Harbor Laboratory | Methods and compositions for RNA interference |
JP4543188B2 (ja) * | 2004-03-10 | 2010-09-15 | 学校法人日本医科大学 | ヒトチミジル酸合成酵素に対するRNAiとして作用するRNA配列 |
JP2008537752A (ja) * | 2005-04-12 | 2008-09-25 | イントラディグム コーポレイション | がんおよび他の新血管形成疾患を処置するためのRNAi治療用の組成物および方法 |
JP2009534342A (ja) * | 2006-04-20 | 2009-09-24 | サイレンス・セラピューティクス・アーゲー | 血管内皮に特異的に送達するためのリポプレックス処方剤 |
WO2008035461A1 (fr) * | 2006-09-22 | 2008-03-27 | Taiho Pharmaceutical Co., Ltd. | Chimiothérapie adjuvante post-opératoire pour un cancer gastrique |
CA2721333C (en) * | 2008-04-15 | 2020-12-01 | Protiva Biotherapeutics, Inc. | Novel lipid formulations for nucleic acid delivery |
WO2009149318A2 (en) * | 2008-06-05 | 2009-12-10 | Research Foundation Of State University Of New York | Mirnas as therapeutic targets in cancer |
KR101579638B1 (ko) * | 2009-03-31 | 2015-12-22 | 데루타-후라이 화마 가부시키가이샤 | 티미딜산 합성효소에 대한 RNAi 분자 및 그의 용도 |
JP5446781B2 (ja) | 2009-11-26 | 2014-03-19 | トヨタ自動車株式会社 | 左右独立駆動車両の駆動ユニット冷却装置 |
-
2011
- 2011-10-14 US US13/273,960 patent/US20120301537A1/en not_active Abandoned
-
2012
- 2012-05-22 EP EP12790050.4A patent/EP2716304B1/en active Active
- 2012-05-22 DK DK12790050.4T patent/DK2716304T3/da active
- 2012-05-22 JP JP2013516384A patent/JP5941460B2/ja active Active
- 2012-05-22 CN CN201280025004.4A patent/CN103561775B/zh active Active
- 2012-05-22 WO PCT/JP2012/063082 patent/WO2012161196A1/ja active Application Filing
- 2012-05-22 PL PL12790050T patent/PL2716304T3/pl unknown
- 2012-05-22 PT PT127900504T patent/PT2716304T/pt unknown
- 2012-05-22 ES ES12790050.4T patent/ES2653923T3/es active Active
- 2012-05-22 NO NO12790050A patent/NO2716304T3/no unknown
- 2012-05-22 HU HUE12790050A patent/HUE037803T2/hu unknown
- 2012-05-23 TW TW101118465A patent/TWI442927B/zh active
-
2014
- 2014-04-14 HK HK14103539.6A patent/HK1190325A1/zh unknown
-
2017
- 2017-12-11 HR HRP20171919TT patent/HRP20171919T1/hr unknown
Also Published As
Publication number | Publication date |
---|---|
HRP20171919T1 (hr) | 2018-02-09 |
JPWO2012161196A1 (ja) | 2014-07-31 |
CN103561775A (zh) | 2014-02-05 |
EP2716304A4 (en) | 2014-10-29 |
DK2716304T3 (da) | 2017-11-27 |
EP2716304B1 (en) | 2017-10-11 |
PT2716304T (pt) | 2018-01-03 |
CN103561775B (zh) | 2016-08-17 |
EP2716304A1 (en) | 2014-04-09 |
HK1190325A1 (zh) | 2014-07-04 |
HUE037803T2 (hu) | 2018-09-28 |
JP5941460B2 (ja) | 2016-06-29 |
TW201300113A (zh) | 2013-01-01 |
WO2012161196A1 (ja) | 2012-11-29 |
US20120301537A1 (en) | 2012-11-29 |
TWI442927B (zh) | 2014-07-01 |
PL2716304T3 (pl) | 2018-03-30 |
ES2653923T3 (es) | 2018-02-09 |