NO20090304L - Fremgangsmater for a attenuere frigjoringen av inflammatoriske mediatorer og nyttige peptider - Google Patents

Fremgangsmater for a attenuere frigjoringen av inflammatoriske mediatorer og nyttige peptider

Info

Publication number
NO20090304L
NO20090304L NO20090304A NO20090304A NO20090304L NO 20090304 L NO20090304 L NO 20090304L NO 20090304 A NO20090304 A NO 20090304A NO 20090304 A NO20090304 A NO 20090304A NO 20090304 L NO20090304 L NO 20090304L
Authority
NO
Norway
Prior art keywords
release
inflammatory mediators
present
methods
inhibiting
Prior art date
Application number
NO20090304A
Other languages
English (en)
Inventor
Indu Parikh
Original Assignee
Biomarck Pharmaceuticals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biomarck Pharmaceuticals Ltd filed Critical Biomarck Pharmaceuticals Ltd
Publication of NO20090304L publication Critical patent/NO20090304L/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10—Peptides having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/10—Anti-acne agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pulmonology (AREA)
  • Dermatology (AREA)
  • Zoology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Transplantation (AREA)
  • Otolaryngology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)

Abstract

Foreliggende oppfinnelse omfatter fremgangsmåter for å hemme eller undertrykke cellulære sekretoriske prosesser. Nærmere bestemt angår foreliggende oppfinnelse hemming eller reduksjon av frigjøringen av inflammatoriske mediatorer fra inflammatoriske celler ved å hemme mekanismen forbundet med frigjøringen av inflammatoriske mediatorer fra granuler i inflammatoriske celler. I dette henseende beskriver foreliggende oppfinnelse en intracellulær signaleringsmekanisme som illustrerer mange nye intracellulære mål for farmakologisk intervensjon i lidelser som involverer sekresjon av inflammatoriske mediatorer fra vesikler i inflammatoriske celler. Peptidfragmenter og varianter derav av MANS-peptid som beskrevet i foreliggende oppfinnelse er anvendelige i slike fremgangsmåter.
NO20090304A 2006-07-26 2009-01-20 Fremgangsmater for a attenuere frigjoringen av inflammatoriske mediatorer og nyttige peptider NO20090304L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US83323906P 2006-07-26 2006-07-26
PCT/US2007/074514 WO2008014414A2 (en) 2006-07-26 2007-07-26 Methods for attenuating release of inflammatory mediators and peptides useful therein

Publications (1)

Publication Number Publication Date
NO20090304L true NO20090304L (no) 2009-04-21

Family

ID=38982357

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20090304A NO20090304L (no) 2006-07-26 2009-01-20 Fremgangsmater for a attenuere frigjoringen av inflammatoriske mediatorer og nyttige peptider

Country Status (22)

Country Link
US (6) US8999915B2 (no)
EP (2) EP2722052B1 (no)
JP (2) JP5378998B2 (no)
KR (1) KR101599894B1 (no)
CN (2) CN103990111B (no)
AU (1) AU2007279193B2 (no)
BR (1) BRPI0714953A2 (no)
CA (2) CA2658949C (no)
DK (2) DK2722052T3 (no)
ES (2) ES2488092T3 (no)
HK (2) HK1125793A1 (no)
HR (1) HRP20140587T1 (no)
IL (1) IL196667A (no)
MX (1) MX2009000975A (no)
NO (1) NO20090304L (no)
PL (2) PL2722052T3 (no)
PT (1) PT2053915E (no)
RU (1) RU2423376C2 (no)
SG (2) SG173411A1 (no)
SI (1) SI2053915T1 (no)
WO (1) WO2008014414A2 (no)
ZA (1) ZA200900550B (no)

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EP1858538B1 (en) 2005-01-20 2019-03-27 Biomarck Pharmaceuticals, Ltd. Mucin hypersecretion inhibitors based on the structure of mans and methods of use
MX2009000975A (es) 2006-07-26 2009-04-07 Biomarck Pharmaceuticals Ltd Metodos para atenuar la liberacion de mediadores inflamatorios y peptidos utiles en ellos.
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RU2681213C2 (ru) * 2013-04-05 2019-03-05 Байомарк Фармасьютикалз, Лтд. Ингибиторы метастазирования
WO2015013669A1 (en) 2013-07-26 2015-01-29 The Regents Of The University Of California Mps peptides and use thereof
US10314889B2 (en) 2013-12-20 2019-06-11 The Regents Of The University Of California Suppression of allergic lung inflammation and hyperreactivity
KR102181548B1 (ko) * 2019-02-20 2020-11-20 한국외국어대학교 연구산학협력단 염증성 질환 또는 자가면역성 질환의 예방 또는 치료 활성을 갖는 펩타이드 및 이의 용도
WO2023212443A1 (en) * 2022-04-25 2023-11-02 Biomarck Pharmaceuticals, Ltd. Peptides and methods of use thereof in treating skin diseases

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Also Published As

Publication number Publication date
SG10201500418QA (en) 2015-03-30
PT2053915E (pt) 2014-08-25
US20230293629A1 (en) 2023-09-21
US20090203620A1 (en) 2009-08-13
US20180036367A1 (en) 2018-02-08
PL2053915T3 (pl) 2014-12-31
MX2009000975A (es) 2009-04-07
EP2053915A2 (en) 2009-05-06
US20210260154A1 (en) 2021-08-26
IL196667A (en) 2017-04-30
EP2053915B1 (en) 2014-06-11
PL2722052T3 (pl) 2019-08-30
US8999915B2 (en) 2015-04-07
JP2013241428A (ja) 2013-12-05
AU2007279193B2 (en) 2011-12-01
CA2842219C (en) 2017-07-11
IL196667A0 (en) 2011-08-01
RU2423376C2 (ru) 2011-07-10
SG173411A1 (en) 2011-08-29
JP5819889B2 (ja) 2015-11-24
EP2722052A1 (en) 2014-04-23
WO2008014414A3 (en) 2008-09-25
SI2053915T1 (sl) 2014-10-30
JP5378998B2 (ja) 2013-12-25
US20200138898A1 (en) 2020-05-07
CA2658949A1 (en) 2008-01-31
RU2009106673A (ru) 2010-09-10
DK2722052T3 (en) 2019-04-29
CN103990111A (zh) 2014-08-20
BRPI0714953A2 (pt) 2013-07-16
AU2007279193A1 (en) 2008-01-31
CN101516190A (zh) 2009-08-26
CN101516190B (zh) 2014-06-11
ES2725599T3 (es) 2019-09-25
HK1201190A1 (en) 2015-08-28
HRP20140587T1 (hr) 2014-11-21
CN103990111B (zh) 2016-08-31
WO2008014414A2 (en) 2008-01-31
US20160030509A1 (en) 2016-02-04
ZA200900550B (en) 2010-03-31
CA2842219A1 (en) 2008-01-31
JP2009544737A (ja) 2009-12-17
ES2488092T3 (es) 2014-08-26
KR20090037487A (ko) 2009-04-15
DK2053915T3 (da) 2014-06-30
US9827287B2 (en) 2017-11-28
KR101599894B1 (ko) 2016-03-04
EP2722052B1 (en) 2019-03-20
CA2658949C (en) 2014-04-22
EP2053915A4 (en) 2011-06-08
HK1125793A1 (en) 2009-08-21

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