NO20090233L - Ny sammensetning som har affinitet for amyloid - Google Patents

Ny sammensetning som har affinitet for amyloid

Info

Publication number
NO20090233L
NO20090233L NO20090233A NO20090233A NO20090233L NO 20090233 L NO20090233 L NO 20090233L NO 20090233 A NO20090233 A NO 20090233A NO 20090233 A NO20090233 A NO 20090233A NO 20090233 L NO20090233 L NO 20090233L
Authority
NO
Norway
Prior art keywords
amyloid
affinity
salt
carbon atoms
substituent
Prior art date
Application number
NO20090233A
Other languages
English (en)
Norwegian (no)
Inventor
Akio Hayashi
Anthony Eamon Storey
Denis Raymond Christophe Bouvet
Daisaku Nakamura
Shigeyuki Tanifuji
Shinya Takasaki
Original Assignee
Nihon Mediphysics Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nihon Mediphysics Co Ltd filed Critical Nihon Mediphysics Co Ltd
Publication of NO20090233L publication Critical patent/NO20090233L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/041—Heterocyclic compounds
    • A61K51/044—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
    • A61K51/0455—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
NO20090233A 2006-06-21 2009-01-14 Ny sammensetning som har affinitet for amyloid NO20090233L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US80535606P 2006-06-21 2006-06-21
JP2006188034 2006-07-07
PCT/JP2007/062503 WO2007148755A1 (ja) 2006-06-21 2007-06-21 新規アミロイド親和性化合物

Publications (1)

Publication Number Publication Date
NO20090233L true NO20090233L (no) 2009-02-11

Family

ID=38833493

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20090233A NO20090233L (no) 2006-06-21 2009-01-14 Ny sammensetning som har affinitet for amyloid

Country Status (10)

Country Link
US (1) US8277777B2 (ja)
EP (1) EP2042501B1 (ja)
KR (1) KR20090025282A (ja)
CN (1) CN101501033B (ja)
AU (1) AU2007261985B2 (ja)
CA (1) CA2655826A1 (ja)
HK (1) HK1133254A1 (ja)
IL (1) IL196046A0 (ja)
NO (1) NO20090233L (ja)
WO (1) WO2007148755A1 (ja)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW200803903A (en) 2006-04-28 2008-01-16 Nihon Mediphysics Co Ltd Novel compound having affinity to amyloid
TW200808795A (en) * 2006-05-19 2008-02-16 Nihon Mediphysics Co Ltd Novel compound having affinity for amyloid
US8207189B2 (en) * 2006-11-30 2012-06-26 Nihon Medi-Physics Co., Ltd. Compound having affinity for amyloid
CA2703649A1 (en) * 2007-10-24 2009-04-30 Shigeyuki Tanifuji Novel compound having affinity for amyloid
AU2008314871A1 (en) * 2007-10-26 2009-04-30 Nihon Medi-Physics Co., Ltd. Novel compound having affinity for amyloid
EP2218464A1 (en) * 2009-02-11 2010-08-18 Technische Universität München Compounds for non-invasive measurement of aggregates of amyloid peptides
KR101123178B1 (ko) * 2009-04-09 2012-06-13 (주)에스메디 2-아릴벤조싸이오펜 유도체 또는 이의 약학적으로 허용가능한 염, 이의 제조방법 및 이를 유효성분으로 함유하는 퇴행성 뇌질환의 진단 또는 치료용 약학적 조성물
KR101854228B1 (ko) * 2011-06-24 2018-05-03 니혼 메디피직스 가부시키가이샤 신규 아밀로이드 친화성 화합물
SG11201508912YA (en) 2013-04-29 2015-11-27 Hoffmann La Roche 2-PHENYL OR 2-HETARYL IMIDAZOL[1,2-a]PYRIDINE DERIVATIVES
CN103724207B (zh) * 2013-12-20 2016-07-06 北京智博高科生物技术有限公司 苯基苄基醚类衍生物及其制备方法和应用
JP6754353B2 (ja) * 2014-08-29 2020-09-09 シーエイチディーアイ ファウンデーション，インコーポレーテッド ハンチントンタンパク質のイメージング用プローブ
US9926316B2 (en) * 2016-03-03 2018-03-27 The Cleveland Clinic Foundation Antitumor derivatives for differentiation therapy
CN108822105A (zh) * 2018-08-14 2018-11-16 河南师范大学 一种由乙苯类化合物合成2-芳基咪唑并[1,2-a]吡啶类化合物的方法

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US4727145A (en) 1986-09-22 1988-02-23 Ortho Pharmaceutical Corporation 2- Or 3- aryl substituted imidazo [1,2-a]pyridines
US4871745A (en) * 1986-09-22 1989-10-03 Ortho Pharmaceutical Corporation 2- or 3-aryl substituted imidazo(1,2-A)pyridines and their use as antisecretory agents
US4791117A (en) * 1986-09-22 1988-12-13 Ortho Pharmaceutical Corporation 2- or 3-aryl substituted imidazo[1,2-a]pyridines and their use as calcium channel blockers
US4833149A (en) * 1986-09-22 1989-05-23 Ortho Pharmaceutical Corporation 2- or 3-aryl substituted imidazo[1,2-a]pyridines
KR19990064310A (ko) * 1995-10-17 1999-07-26 윌리암스 로저 에이 시클로옥시게나제-2의 검출방법
US6812327B1 (en) * 1996-10-25 2004-11-02 Human Genome Sciences, Inc. Neutrokine-alpha polypeptides
CA2340394A1 (en) 1998-08-20 2000-03-02 Jorge R. Barrio Methods for labeling .beta.-amyloid plaques and neurofibrillary tangles
JP4025468B2 (ja) 1999-07-29 2007-12-19 三井化学株式会社 有機電界発光素子
WO2001074813A2 (en) * 2000-03-31 2001-10-11 Ortho Mcneil Pharmaceutical, Inc. METHOD FOR USING 2- OR 3-ARYL SUBSTITUTED IMIDAZO[1,2-a] PYRIDINES AS H3 ANTAGONISTS
US20010051632A1 (en) * 2000-03-31 2001-12-13 Wenying Chai Phenyl-substituted indolizines and tetrahydroindolizines
DE60128211T2 (de) 2000-03-31 2008-01-10 Ortho-Mcneil Pharmaceutical, Inc. Phenyl-substituierte imidazopyridine
US6514969B2 (en) * 2000-08-16 2003-02-04 Boehringer Ingelheim Pharma Kg β-amyloid inhibitors, processes for preparing them, and their use in pharmaceutical compositions
DE10040016A1 (de) 2000-08-16 2002-02-28 Boehringer Ingelheim Pharma Neue beta-Amyloid Inhibitoren, Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel
JP5022554B2 (ja) 2000-08-24 2012-09-12 ユニバーシティ オブ ピッツバーグ オブ ザ コモンウェルス システム オブ ハイヤー エデュケイション アルツハイマー病の生前診断ならびにアミロイド沈着物のインビボ画像化および予防に用いるためのチオフラビン誘導体
IL157359A0 (en) * 2001-02-26 2004-02-19 Bristol Myers Squibb Pharma Co A radiopharmaceutical composition containing an ascorbic acid analog
US6596731B2 (en) * 2001-03-27 2003-07-22 Hoffmann-La Roche Inc. Substituted imidazo[1,2-A] pyridine derivatives
TWI245764B (en) * 2001-04-23 2005-12-21 Hank F Kung Amyloid plaque aggregation inhibitors and diagnostic imaging agents
DK1432453T3 (da) 2001-08-27 2013-11-18 Univ Pennsylvania Stilbenderivater og anvendelse heraf til binding og billeddannelse af amyloid-plaques
GB0205281D0 (en) * 2002-03-06 2002-04-17 Novartis Ag Organic compounds
EP1356827A1 (en) * 2002-04-24 2003-10-29 Mallinckrodt Inc. Method for obtaining a 2-18F-fluor-2-deoxy-D-glucose (18F-FDG)-solution
AU2003242233A1 (en) * 2002-06-12 2003-12-31 Bf Research Institute, Inc. Probe compound for image diagnosis of disease with amyloid accumulation, compound for staining age spots/diffuse age spots, and remedy for disease with amyloid accumulation
ATE473019T1 (de) 2002-11-05 2010-07-15 Ion Beam Applic Sa Stabilisierung von wässerigen zusammensetzungen von 18f-markiertem 2-fluoro-2-deoxy-d-glukose mit ethanol
GB0229695D0 (en) * 2002-12-20 2003-01-29 Amersham Plc Solid-phase preparation of 18F-labelled amino acids
WO2005066177A1 (en) * 2003-12-31 2005-07-21 Schering-Plough Ltd. Control of parasites in animals by the use of imidazo[1,2-b]pyridazine derivatives
EP1893245A4 (en) * 2005-06-24 2009-06-24 Univ Pennsylvania RADIOACTIVELY MARKED PEGYLATION OF LIGANDS FOR USE AS A CONTRAST
WO2007033080A2 (en) * 2005-09-12 2007-03-22 Emory University Alzheimer's disease imaging agents
TW200808795A (en) * 2006-05-19 2008-02-16 Nihon Mediphysics Co Ltd Novel compound having affinity for amyloid
CA2703649A1 (en) * 2007-10-24 2009-04-30 Shigeyuki Tanifuji Novel compound having affinity for amyloid
AU2008314871A1 (en) * 2007-10-26 2009-04-30 Nihon Medi-Physics Co., Ltd. Novel compound having affinity for amyloid
US20100249419A1 (en) * 2007-10-30 2010-09-30 Nihon Medi-Physics Co., Ltd. Utilization of novel compounds with amyloid affinity and method of producing the same

Also Published As

Publication number Publication date
AU2007261985B2 (en) 2012-04-19
HK1133254A1 (en) 2010-03-19
IL196046A0 (en) 2009-09-01
EP2042501B1 (en) 2017-04-12
EP2042501A4 (en) 2012-11-21
CN101501033B (zh) 2012-08-01
EP2042501A1 (en) 2009-04-01
US8277777B2 (en) 2012-10-02
CA2655826A1 (en) 2007-12-27
KR20090025282A (ko) 2009-03-10
US20100092387A1 (en) 2010-04-15
WO2007148755A1 (ja) 2007-12-27
CN101501033A (zh) 2009-08-05
AU2007261985A1 (en) 2007-12-27

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