NO20085213L - Nye pyridinanaloger - Google Patents

Nye pyridinanaloger

Info

Publication number
NO20085213L
NO20085213L NO20085213A NO20085213A NO20085213L NO 20085213 L NO20085213 L NO 20085213L NO 20085213 A NO20085213 A NO 20085213A NO 20085213 A NO20085213 A NO 20085213A NO 20085213 L NO20085213 L NO 20085213L
Authority
NO
Norway
Prior art keywords
new pyridine
pyridine analogs
formula
analogs
new
Prior art date
Application number
NO20085213A
Other languages
English (en)
Inventor
Johan Johansson
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of NO20085213L publication Critical patent/NO20085213L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/455—Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Foreliggende oppfinnelse angår visse nye pyridinanaloger med formel ( I ) Formel ( I ) til prosesser for fremstilling av slike forbindelser, til deres nytte som P2Y12 inhibitorer og som anti-trombotiske midler etc, anvendelse av dem som medikamenter i kardiovaskulære sykdommer så vel som farmasøytiske preparater inneholdende dem.
NO20085213A 2006-07-04 2008-12-15 Nye pyridinanaloger NO20085213L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE0601465 2006-07-04
PCT/SE2007/000641 WO2008004941A1 (en) 2006-07-04 2007-07-02 New pyridine analogues

Publications (1)

Publication Number Publication Date
NO20085213L true NO20085213L (no) 2009-01-13

Family

ID=38894820

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20085213A NO20085213L (no) 2006-07-04 2008-12-15 Nye pyridinanaloger

Country Status (13)

Country Link
US (2) US20090312368A1 (no)
EP (1) EP2041112A1 (no)
JP (1) JP2009542641A (no)
KR (1) KR20090031605A (no)
CN (1) CN101506193A (no)
AU (1) AU2007270081A1 (no)
BR (1) BRPI0713401A2 (no)
CA (1) CA2655628A1 (no)
IL (1) IL195979A0 (no)
MX (1) MX2008016551A (no)
NO (1) NO20085213L (no)
WO (1) WO2008004941A1 (no)
ZA (1) ZA200810647B (no)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090227555A2 (en) * 2005-01-06 2009-09-10 Astrazeneca Ab Novel Pyridine Compounds
WO2007008140A1 (en) * 2005-07-13 2007-01-18 Astrazeneca Ab New pyridine analogues
AU2007270083A1 (en) * 2006-07-04 2008-01-10 Astrazeneca Ab New pyridine analogues
MX2008016551A (es) * 2006-07-04 2009-02-06 Astrazeneca Ab Analogos de piridina nuevos.
AU2007270082A1 (en) * 2006-07-04 2008-01-10 Astrazeneca Ab New pyridine analogues
TW200811133A (en) * 2006-07-04 2008-03-01 Astrazeneca Ab New pyridine analogues III 334
AU2008203953A1 (en) * 2007-01-12 2008-07-17 Astrazeneca Ab Pyridine compounds and their use as P2Y12 antagonists.
UY30867A1 (es) * 2007-01-12 2008-09-02 Astrazeneca Ab Nuevos analogos de piridina vii 543
AR064865A1 (es) * 2007-07-13 2009-04-29 Astrazeneca Ab Derivados de piridina antagonistas de p2y12
AR074628A1 (es) * 2008-07-07 2011-02-02 Astrazeneca Ab Derivados de piridina 2- amino-6-alquil sustituidos utiles como inhibidores de p2y12 308
EP2750676B1 (en) 2011-08-30 2018-01-10 University of Utah Research Foundation Methods and compositions for treating nephrogenic diabetes insipidus

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6156758A (en) * 1999-09-08 2000-12-05 Isis Pharmaceuticals, Inc. Antibacterial quinazoline compounds
US6906063B2 (en) * 2000-02-04 2005-06-14 Portola Pharmaceuticals, Inc. Platelet ADP receptor inhibitors
DK1257550T3 (da) * 2000-02-04 2006-03-27 Portola Pharm Inc Blodplade-ADP-receptor-inhibitor
US7452870B2 (en) * 2000-08-21 2008-11-18 Inspire Pharmaceuticals, Inc. Drug-eluting stents coated with P2Y12 receptor antagonist compound
US7018985B1 (en) * 2000-08-21 2006-03-28 Inspire Pharmaceuticals, Inc. Composition and method for inhibiting platelet aggregation
US7132408B2 (en) * 2000-08-21 2006-11-07 Inspire Pharmaceuticals, Inc. Composition and method for inhibiting platelet aggregation
FR2820057A1 (fr) * 2001-01-30 2002-08-02 Ct De Transfert De Technologie Membrane pour chambre d'encapsulation de cellules produisant au moins une substance biologiquement active et organe bio-artificiel comprenant une telle membrane
KR20060041309A (ko) * 2003-08-13 2006-05-11 다케다 야쿠힌 고교 가부시키가이샤 ４-피리미돈 유도체 및 펩티딜 펩티다제 저해제로서의 그의용도
EP1667989A4 (en) * 2003-10-03 2008-08-20 Portola Pharm Inc SUBSTITUTED ISOQUINOLEINONES
US7504497B2 (en) * 2003-10-21 2009-03-17 Inspire Pharmaceuticals, Inc. Orally bioavailable compounds and methods for inhibiting platelet aggregation
US7749981B2 (en) * 2003-10-21 2010-07-06 Inspire Pharmaceuticals, Inc. Drug-eluting stents coated with non-nucleotide P2Y12 receptor antagonist compound
US7335648B2 (en) * 2003-10-21 2008-02-26 Inspire Pharmaceuticals, Inc. Non-nucleotide composition and method for inhibiting platelet aggregation
EA200700117A1 (ru) * 2004-06-24 2007-06-29 Инсайт Корпорейшн N-замещенные пиперидины и их применение в качестве фармацевтических препаратов
US20090227555A2 (en) * 2005-01-06 2009-09-10 Astrazeneca Ab Novel Pyridine Compounds
WO2007008140A1 (en) * 2005-07-13 2007-01-18 Astrazeneca Ab New pyridine analogues
AU2007270082A1 (en) * 2006-07-04 2008-01-10 Astrazeneca Ab New pyridine analogues
MX2008016551A (es) * 2006-07-04 2009-02-06 Astrazeneca Ab Analogos de piridina nuevos.
TW200811133A (en) * 2006-07-04 2008-03-01 Astrazeneca Ab New pyridine analogues III 334
AU2007270083A1 (en) * 2006-07-04 2008-01-10 Astrazeneca Ab New pyridine analogues
UY30867A1 (es) * 2007-01-12 2008-09-02 Astrazeneca Ab Nuevos analogos de piridina vii 543
AU2008203953A1 (en) * 2007-01-12 2008-07-17 Astrazeneca Ab Pyridine compounds and their use as P2Y12 antagonists.
CL2008000093A1 (es) * 2007-01-12 2008-08-22 Astrazeneca Ab Compuestos derivados de piridina, inhibidores de p2y12; composicion farmaceutica que comprende a dichos compuestos; y su uso para el tratamiento de un desorden de agregacion plaquetaria.
AR064865A1 (es) * 2007-07-13 2009-04-29 Astrazeneca Ab Derivados de piridina antagonistas de p2y12

Also Published As

Publication number Publication date
EP2041112A1 (en) 2009-04-01
WO2008004941A1 (en) 2008-01-10
US20090312368A1 (en) 2009-12-17
IL195979A0 (en) 2009-09-01
AU2007270081A1 (en) 2008-01-10
JP2009542641A (ja) 2009-12-03
KR20090031605A (ko) 2009-03-26
CA2655628A1 (en) 2008-01-10
US20080009523A1 (en) 2008-01-10
ZA200810647B (en) 2009-12-30
MX2008016551A (es) 2009-02-06
BRPI0713401A2 (pt) 2012-04-17
CN101506193A (zh) 2009-08-12

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Legal Events

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