NO20076423L - Hydrazidkonjugater som billeddannende midler - Google Patents
Hydrazidkonjugater som billeddannende midlerInfo
- Publication number
- NO20076423L NO20076423L NO20076423A NO20076423A NO20076423L NO 20076423 L NO20076423 L NO 20076423L NO 20076423 A NO20076423 A NO 20076423A NO 20076423 A NO20076423 A NO 20076423A NO 20076423 L NO20076423 L NO 20076423L
- Authority
- NO
- Norway
- Prior art keywords
- plaque
- imaging
- detecting
- arterial
- disclosure relates
- Prior art date
Links
- 239000012216 imaging agent Substances 0.000 title 1
- 229940039227 diagnostic agent Drugs 0.000 abstract 2
- 239000000032 diagnostic agent Substances 0.000 abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- 238000003384 imaging method Methods 0.000 abstract 2
- 238000012544 monitoring process Methods 0.000 abstract 2
- 206010002329 Aneurysm Diseases 0.000 abstract 1
- 206010047115 Vasculitis Diseases 0.000 abstract 1
- 210000001367 artery Anatomy 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000001575 pathological effect Effects 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 238000007634 remodeling Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
- A61K49/085—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier conjugated systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/0002—General or multifunctional contrast agents, e.g. chelated agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
- A61K49/10—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A61K51/088—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C243/00—Compounds containing chains of nitrogen atoms singly-bound to each other, e.g. hydrazines, triazanes
- C07C243/24—Hydrazines having nitrogen atoms of hydrazine groups acylated by carboxylic acids
- C07C243/38—Hydrazines having nitrogen atoms of hydrazine groups acylated by carboxylic acids with acylating carboxyl groups bound to carbon atoms of six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
- C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C271/22—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
- C07D209/16—Tryptamines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
- C07D213/82—Amides; Imides in position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
- C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/02—Linear peptides containing at least one abnormal peptide link
Abstract
Foreliggende beskrivelse angår diagnostiske midler. Mer spesifikt angår beskrivelsen forbindelser, diagnostiske midler, preparater og sett for detektering og/eller avbildning og/eller overvåkning av en patologisk lidelse forbundet med koronar plaque, karotid plaque, aorta plaque, plaque i arterielle kar, aneurisme, vaskulitt og andre sykdommer i arterieveggen. I tillegg angår beskrivelsen metoder for detektering og/eller avbildning og/eller overvåkning av endringer på arterieveggen, omfattende ekspansiv og konstriktiv remodellering, totalt karvegg-areal, indre lumen størrelse og ytre arterie-perimeter.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US69549605P | 2005-06-30 | 2005-06-30 | |
PCT/US2006/025298 WO2007005491A1 (en) | 2005-06-30 | 2006-06-28 | Hydrazide conjugates as imaging agents |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20076423L true NO20076423L (no) | 2008-03-27 |
Family
ID=37137580
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20076423A NO20076423L (no) | 2005-06-30 | 2007-12-14 | Hydrazidkonjugater som billeddannende midler |
Country Status (9)
Country | Link |
---|---|
US (1) | US20070014721A1 (no) |
EP (1) | EP1896086A1 (no) |
JP (1) | JP2009500410A (no) |
KR (1) | KR20080022588A (no) |
CN (1) | CN101252954A (no) |
AU (1) | AU2006266074A1 (no) |
CA (1) | CA2613439A1 (no) |
NO (1) | NO20076423L (no) |
WO (1) | WO2007005491A1 (no) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2009089022A1 (en) * | 2008-01-08 | 2009-07-16 | Lantheus Medical Imaging, Inc. | N-alkoxyamide conjugates as imaging agents |
EP2384323A4 (en) * | 2008-11-11 | 2013-07-31 | Univ Nanyang Tech | INTRAVASCULAR CONTRAST AGENTS |
CN102781909B (zh) | 2009-07-08 | 2015-06-17 | 兰休斯医疗成像公司 | 作为显像剂的n-烷氧基酰胺共轭物 |
US9144415B2 (en) | 2010-03-26 | 2015-09-29 | The University Of Tokushima | Carotid-artery-plaque ultrasound-imaging method and evaluating device |
CN102558291B (zh) * | 2010-12-17 | 2014-03-12 | 北京大学人民医院 | 一种双模分子影像探针 |
GB201102189D0 (en) | 2011-02-08 | 2011-03-23 | King S College London | Materials and methods relating to cardiovascular imaging |
ES2748940T3 (es) | 2011-11-11 | 2020-03-18 | Univ Yale | Evaluación de la presencia de una fibrilación auricular y de la vulnerabilidad a ésta, y otras indicaciones sobre la base de la toma de imágenes basada en metaloproteinasas de matriz |
JP2018513879A (ja) * | 2015-04-17 | 2018-05-31 | サイミック アイピー, エルエルシー | バイオコンジュゲートおよびその使用 |
CN110809478A (zh) | 2017-07-07 | 2020-02-18 | 斯米克Ip有限公司 | 合成的生物缀合物 |
MA50247B1 (fr) | 2017-10-16 | 2021-02-26 | Faes Farma Sa | Compositions aqueuses comprenant de la bilastine et du mométasone |
MX2018003175A (es) * | 2018-03-14 | 2019-09-16 | Instituto Nac De Investigaciones Nucleares | 177lu-dota-hynic-ipsma como un radiofarmaco terapeutico dirigido al antigeno prostatico especifico de membrana. |
WO2022178592A1 (en) * | 2021-02-26 | 2022-09-01 | Telix International Pty Ltd | Solid phase synthesis of glutamate-urea-lysine derived (gul derived) prostate-specific membrane antigen (psma) targeting conjugates and their use as precursors for therapeutic and / or diagnostic agents |
Family Cites Families (31)
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US4859777A (en) * | 1981-07-01 | 1989-08-22 | Eastman Kodak Company | Terpyridine chelating agents |
US4452774A (en) * | 1982-04-30 | 1984-06-05 | President And Fellows Of Harvard College | Isonitrile radionuclide complexes for labelling and imaging agents |
JPH07110815B2 (ja) * | 1985-11-18 | 1995-11-29 | ボ−ド・オブ・リ−ジェンツ、ザ・ユニバ−シティ−・オブ・テキサス・システム | 画像及びスペクトル向上(およびスペクトルシフト)のためのポリキレ−ト剤 |
CA1305160C (en) * | 1985-12-23 | 1992-07-14 | Paul Louis Bergstein | Ether isonitriles and radiolabeled complexes thereof |
US4913891A (en) * | 1986-04-17 | 1990-04-03 | The United States Of America As Represented By The United States Department Of Energy | Positron emitter labeled enzyme inhibitors |
US5252317A (en) * | 1986-11-10 | 1993-10-12 | The State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of The University Of Oregon | Amplifier molecules for diagnosis and therapy derived from 3,5-bis[1-(3-amino-2,2-bis (aminomethyl)-propyl) oxymethyl] benzoic acid |
US5567411A (en) * | 1986-11-10 | 1996-10-22 | State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of The University Of Oregon | Dendritic amplifier molecules having multiple terminal active groups stemming from a benzyl core group |
US5064956A (en) * | 1987-06-24 | 1991-11-12 | The Dow Chemical Company | Process for preparing mono-n-alkylated polyazamacrocycles |
US5026537A (en) * | 1989-04-06 | 1991-06-25 | Centocor, Inc. | Methods for imaging atherosclerotic plaque |
US5087440A (en) * | 1989-07-31 | 1992-02-11 | Salutar, Inc. | Heterocyclic derivatives of DTPA used for magnetic resonance imaging |
GB8923843D0 (en) * | 1989-10-23 | 1989-12-13 | Salutar Inc | Compounds |
GB9006977D0 (en) * | 1990-03-28 | 1990-05-23 | Nycomed As | Compositions |
IE920996A1 (en) * | 1991-03-27 | 1992-10-07 | Nycomed Salutar | Contrast media |
GB9209641D0 (en) * | 1992-05-02 | 1992-06-17 | Johnson Matthey Plc | Improvements in radiolabelling |
US5760191A (en) * | 1993-02-05 | 1998-06-02 | Nycomed Imaging As | Macrocyclic complexing agents and targeting immunoreagents useful in therapeutic and diagnostic compositions and methods |
US5750088A (en) * | 1993-03-30 | 1998-05-12 | The Dupont Merck Pharmaceutical Company | Stable hydrazones linked to a peptide moiety as reagents for the preparation of radiopharmaceuticals |
US5744120A (en) * | 1993-03-30 | 1998-04-28 | The Dupont Merick Pharmaceutical Company | Ternary radiopharmaceutical complexes |
HU222574B1 (hu) * | 1993-03-31 | 2003-08-28 | Mallinckrodt Medical Inc. | Redukálószerként foszfinokat tartalmazó radioaktív gyógyászati készítmények és az ezeket tartalmazó készletek |
US5417959A (en) * | 1993-10-04 | 1995-05-23 | Mallinckrodt Medical, Inc. | Functionalized aza-crytand ligands for diagnostic imaging applications |
US5520904A (en) * | 1995-01-27 | 1996-05-28 | Mallinckrodt Medical, Inc. | Calcium/oxyanion-containing particles with a polymerical alkoxy coating for use in medical diagnostic imaging |
SE515621C2 (sv) * | 1995-05-08 | 2001-09-10 | Ericsson Telefon Ab L M | Förfarande vid lägesbestämning |
US5801228A (en) * | 1995-06-07 | 1998-09-01 | Nycomed Imaging As | Polymeric contrast agents for medical imaging |
IT1275571B (it) * | 1995-07-19 | 1997-08-07 | Consiglio Nazionale Ricerche | Substrati fluorogenici suscettibili di fotoattivazione previa trasformazione per via enzimatica atti alla diagnosi ed alla terapia fotodinamica dei tumori |
DK0907379T3 (da) * | 1996-04-01 | 2004-08-16 | Epix Medical Inc | Bioaktiveret diagnostisk billeddannelseskontrastmiddel |
US5804161A (en) * | 1996-05-14 | 1998-09-08 | Nycomed Salutar Inc. | Contrast agents |
DE19717904A1 (de) * | 1997-04-23 | 1998-10-29 | Diagnostikforschung Inst | Säurelabile und enzymatisch spaltbare Farbstoffkonstrukte zur Diagnostik mit Nahinfrarotlicht und zur Therapie |
EP2324857A1 (en) * | 1997-09-08 | 2011-05-25 | The General Hospital Corporation | Imaging agents for early detection of cardiovascular plaque |
US6083486A (en) * | 1998-05-14 | 2000-07-04 | The General Hospital Corporation | Intramolecularly-quenched near infrared fluorescent probes |
US5980863A (en) * | 1998-11-02 | 1999-11-09 | Eagle Vision Pharmaceutical Corporation | Manganese compositions and methods for MRI |
US6254852B1 (en) * | 1999-07-16 | 2001-07-03 | Dupont Pharmaceuticals Company | Porous inorganic targeted ultrasound contrast agents |
AU2002254158A1 (en) * | 2001-03-08 | 2002-09-24 | Volcano Therapeutics, Inc. | Medical devices, compositions and methods for treating vulnerable plaque |
-
2006
- 2006-06-28 JP JP2008520284A patent/JP2009500410A/ja active Pending
- 2006-06-28 US US11/476,377 patent/US20070014721A1/en not_active Abandoned
- 2006-06-28 AU AU2006266074A patent/AU2006266074A1/en not_active Abandoned
- 2006-06-28 EP EP06774241A patent/EP1896086A1/en not_active Withdrawn
- 2006-06-28 WO PCT/US2006/025298 patent/WO2007005491A1/en active Application Filing
- 2006-06-28 CN CNA2006800314144A patent/CN101252954A/zh active Pending
- 2006-06-28 KR KR1020087002397A patent/KR20080022588A/ko not_active Application Discontinuation
- 2006-06-28 CA CA002613439A patent/CA2613439A1/en not_active Abandoned
-
2007
- 2007-12-14 NO NO20076423A patent/NO20076423L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
WO2007005491B1 (en) | 2007-04-12 |
AU2006266074A1 (en) | 2007-01-11 |
CN101252954A (zh) | 2008-08-27 |
US20070014721A1 (en) | 2007-01-18 |
KR20080022588A (ko) | 2008-03-11 |
WO2007005491A1 (en) | 2007-01-11 |
EP1896086A1 (en) | 2008-03-12 |
CA2613439A1 (en) | 2007-01-11 |
JP2009500410A (ja) | 2009-01-08 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FC2A | Withdrawal, rejection or dismissal of laid open patent application |