NO20076307L - Fremgangsmater for a fremstille biarylurinstoffer og analoger derav - Google Patents

Fremgangsmater for a fremstille biarylurinstoffer og analoger derav

Info

Publication number
NO20076307L
NO20076307L NO20076307A NO20076307A NO20076307L NO 20076307 L NO20076307 L NO 20076307L NO 20076307 A NO20076307 A NO 20076307A NO 20076307 A NO20076307 A NO 20076307A NO 20076307 L NO20076307 L NO 20076307L
Authority
NO
Norway
Prior art keywords
preparing
analogs
biarylurine
substances
methods
Prior art date
Application number
NO20076307A
Other languages
English (en)
Inventor
John R Snoonian
Adam Looker
Graham Ansell
Todd A Blythe
Andrew D Jones
Benjamin Littler
Philip L Nyce
Original Assignee
Vertex Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vertex Pharma filed Critical Vertex Pharma
Publication of NO20076307L publication Critical patent/NO20076307L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C275/32—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by singly-bound oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/04—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D307/18—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/20—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Foreliggende oppfinnelse vedrører fremgangsmåter for å fremstille biarylureaderivater og analoger derav. Oppfinnelsen tilveiebringer også forbindelser som er nyttige som mellomprodukter i fremgangsmåtene ifølge foreliggende oppfinnelse. Fremgangsmåten er nyttig for å fremstille forbindelser som hemmer IMPDH.
NO20076307A 2005-05-09 2007-12-07 Fremgangsmater for a fremstille biarylurinstoffer og analoger derav NO20076307L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US67902205P 2005-05-09 2005-05-09
PCT/US2006/017817 WO2006122072A2 (en) 2005-05-09 2006-05-09 Processes for preparing biaryl ureas and analogs thereof

Publications (1)

Publication Number Publication Date
NO20076307L true NO20076307L (no) 2007-12-07

Family

ID=37101964

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20076307A NO20076307L (no) 2005-05-09 2007-12-07 Fremgangsmater for a fremstille biarylurinstoffer og analoger derav

Country Status (15)

Country Link
US (2) US7544810B2 (no)
EP (1) EP1879858A2 (no)
JP (1) JP2008543742A (no)
KR (1) KR20080015433A (no)
CN (1) CN101175718A (no)
AU (1) AU2006244173A1 (no)
BR (1) BRPI0608602A2 (no)
CA (1) CA2606780A1 (no)
IL (1) IL186803A (no)
MX (1) MX2007014187A (no)
NO (1) NO20076307L (no)
NZ (1) NZ563478A (no)
RU (1) RU2431630C2 (no)
WO (1) WO2006122072A2 (no)
ZA (1) ZA200709241B (no)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019168874A1 (en) 2018-02-27 2019-09-06 The Research Foundation For The State University Of New York Difluoromethoxylation and trifluoromethoxylation compositions and methods for synthesizing same
TW202128675A (zh) 2019-12-06 2021-08-01 美商維泰克斯製藥公司 作為鈉通道調節劑之經取代四氫呋喃
PE20241335A1 (es) 2021-06-04 2024-07-03 Vertex Pharma N-(hidroxialquil (hetero)aril) tetrahidrofurano carboxamidas como moduladores de canales de sodio

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5807876A (en) * 1996-04-23 1998-09-15 Vertex Pharmaceuticals Incorporated Inhibitors of IMPDH enzyme
US6054472A (en) 1996-04-23 2000-04-25 Vertex Pharmaceuticals, Incorporated Inhibitors of IMPDH enzyme
NZ332405A (en) * 1996-04-23 2000-06-23 Vertex Pharma oxazolyl, thiazolyl or phenyl urea derivatives as inhibitors of inosine monophosphate dehydrogenase enzyme
US6420403B1 (en) * 1998-10-29 2002-07-16 Edwin J. Iwanowicz Inhibitors of IMPDH enzyme
TR200103428T2 (tr) 1999-03-19 2002-04-22 Vertex Pharmaceuticals Incorporated IMPDH enzim inhibitörleri.
WO2001099028A1 (en) * 2000-06-21 2001-12-27 Exxonmobil Upstream Research Company Orthogonal triaxial acoustic receiver

Also Published As

Publication number Publication date
IL186803A0 (en) 2008-02-09
AU2006244173A1 (en) 2006-11-16
WO2006122072A2 (en) 2006-11-16
EP1879858A2 (en) 2008-01-23
NZ563478A (en) 2011-04-29
RU2431630C2 (ru) 2011-10-20
JP2008543742A (ja) 2008-12-04
CA2606780A1 (en) 2006-11-16
IL186803A (en) 2012-02-29
CN101175718A (zh) 2008-05-07
RU2007145420A (ru) 2009-06-20
ZA200709241B (en) 2009-02-25
US20090221835A1 (en) 2009-09-03
WO2006122072A3 (en) 2007-05-03
KR20080015433A (ko) 2008-02-19
BRPI0608602A2 (pt) 2010-01-19
MX2007014187A (es) 2008-01-24
US20080021222A1 (en) 2008-01-24
US7777048B2 (en) 2010-08-17
US7544810B2 (en) 2009-06-09

Similar Documents

Publication Publication Date Title
NO20074093L (no) Fremgangsmater for fremstilling av glukopyranosyl-substituerte benzyl-benzenderivater og mellomprodukter derav
NO20085385L (no) Tiazolforbindelser som cannabinoidreseptorligander og anvendelser derav
EA201200669A1 (ru) ПИРИДОПИРИМИДИНОНОВЫЕ ИНГИБИТОРЫ PI3Kα
UA107175C2 (uk) Спосіб і сполука, призначені для одержання інгібіторів контранспортера натрій-глюкози 2 типу, варіанти
EA201070912A1 (ru) Производные оксима в качестве ингибиторов hsp90
DE602008005771D1 (de) Disubstituierte alkyl-8-azabicycloä3.2.1üoktan-verbindungen als mu-opioid-rezeptorantagonisten
EA201000642A1 (ru) 2'-фтор-2'-дезокситетрагидроуридины в качестве ингибиторов цитидиндеаминазы
NO20076371L (no) Fremgangsmate for fremstilling av fenoliske 4-bifenylylazetidin-2-oner
EA201170282A1 (ru) Фунгицидные n-циколоалкил-n-бифенилметилкарбоксамидные производные
EA200601295A1 (ru) Производные 1,3-диоксана и их аналоги, применимые для лечения i.a. ожирения и диабета
TW200633977A (en) Novel process for the manufacture of 3-pyrrolidin-2-yl-propionic acid derivatives
NO20063944L (no) Piperidinylkarbonyl-pyrrolidiner og deres anvendelse som melanokortinagonister
EA200900090A1 (ru) Бензиламины, способ их получения и их применение в качестве противовоспалительных средств
DK1761478T3 (da) En isoleret Atomoxetin urenhed, fremgangsmåde til fremstilling af Atomoxetin urenheder og deres anvendelse som referencestandarder
EA200870038A1 (ru) Способ получения аминов
NO20081621L (no) Tetrahydrokinoliner, syntese og intermediater
NO20080468L (no) Diazepinokinoliner, synteser av disse samt intermediater
TNSN06260A1 (en) Process for the preparation of tryptase inhibitors
MX2007007446A (es) Procesos para la produccion de 4-aminoquinazolinas.
NO20081207L (no) Isoquinolines as IGF-1R inhibitors
EA200701852A1 (ru) Производные аминокислот
NO20090234L (no) Tricyklisk sammensetning og farmasoytisk anvendelse derav
NO20080553L (no) Azinyl-3-sulfonylindazolderivater som 5-hydroksytrypyamin-6 ligander
ATE465152T1 (de) Verfahren zum herstellen von alkylaniliden aus halogenbenzolderivaten
NO20076307L (no) Fremgangsmater for a fremstille biarylurinstoffer og analoger derav

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application