NO20074739L - Amidderivater som ionkanalligander og farmasoytiske sammensetninger og fremgangsmater for anvendelse av samme - Google Patents
Amidderivater som ionkanalligander og farmasoytiske sammensetninger og fremgangsmater for anvendelse av sammeInfo
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- NO20074739L NO20074739L NO20074739A NO20074739A NO20074739L NO 20074739 L NO20074739 L NO 20074739L NO 20074739 A NO20074739 A NO 20074739A NO 20074739 A NO20074739 A NO 20074739A NO 20074739 L NO20074739 L NO 20074739L
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- same
- pharmaceutical compositions
- ion channel
- amide derivatives
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- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
- C07D317/50—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
- C07D317/52—Radicals substituted by halogen atoms or nitro radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
- C07D317/50—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
- C07D317/58—Radicals substituted by nitrogen atoms
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
- C07D319/14—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
- C07D319/16—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D319/18—Ethylenedioxybenzenes, not substituted on the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
- C07D491/052—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being six-membered
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
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Applications Claiming Priority (15)
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US65698405P | 2005-02-28 | 2005-02-28 | |
US71044505P | 2005-08-23 | 2005-08-23 | |
US77605606P | 2006-02-23 | 2006-02-23 | |
US77594906P | 2006-02-23 | 2006-02-23 | |
US77603306P | 2006-02-23 | 2006-02-23 | |
US77605706P | 2006-02-23 | 2006-02-23 | |
US77610506P | 2006-02-23 | 2006-02-23 | |
US77593006P | 2006-02-23 | 2006-02-23 | |
US77610606P | 2006-02-23 | 2006-02-23 | |
US77606406P | 2006-02-23 | 2006-02-23 | |
US77605806P | 2006-02-23 | 2006-02-23 | |
US77594506P | 2006-02-23 | 2006-02-23 | |
PCT/US2006/006615 WO2006093832A2 (fr) | 2005-02-28 | 2006-02-24 | Derives d'amide en tant que ligands de canal ionique, compositions pharmaceutiques et methodes d'utilisation associees |
US83999406P | 2006-08-24 | 2006-08-24 | |
US83990306P | 2006-08-24 | 2006-08-24 |
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NO20074739L true NO20074739L (no) | 2007-11-15 |
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NO20074739A NO20074739L (no) | 2005-02-28 | 2007-09-17 | Amidderivater som ionkanalligander og farmasoytiske sammensetninger og fremgangsmater for anvendelse av samme |
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JP (1) | JP2008531690A (fr) |
KR (1) | KR20070119655A (fr) |
AP (1) | AP2007004119A0 (fr) |
AU (2) | AU2006218824A1 (fr) |
CA (1) | CA2600933A1 (fr) |
NO (1) | NO20074739L (fr) |
WO (2) | WO2006093832A2 (fr) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
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AP2007004119A0 (en) * | 2005-02-28 | 2007-08-31 | Renovis Inc | Amide derivatives as ion-channel ligands and pharmaceutical compositions and methods of using the same |
WO2008109178A1 (fr) * | 2007-03-07 | 2008-09-12 | Alantos Pharmaceuticals Holding, Inc. | Inhibiteurs de métalloprotéase contenant une fraction squaramide |
EP2162136A4 (fr) * | 2007-06-03 | 2012-02-15 | Univ Vanderbilt | Dérivés benzamides modulateurs allostériques positifs récepteurs métabotropiques du glutamate 5 (mglur5) et leurs procédés de fabrication et d'utilisation |
US8853392B2 (en) | 2007-06-03 | 2014-10-07 | Vanderbilt University | Benzamide mGluR5 positive allosteric modulators and methods of making and using same |
ES2372655T3 (es) * | 2007-11-13 | 2012-01-25 | Evotec Ag | Derivados amídicos como ligandos de canales iónicos y composiciones farmacéuticas y métodos de uso de los mismos. |
MX356032B (es) * | 2007-11-16 | 2018-04-11 | Neuraxon Inc | Compuestos indola y métodos para tratar el dolor visceral. |
FR2933977B1 (fr) * | 2008-07-18 | 2013-04-26 | Centre Nat Rech Scient | Derives heterocycliques utiles dans le traitement des maladies neurodegeneratives |
US8809380B2 (en) | 2009-08-04 | 2014-08-19 | Raqualia Pharma Inc. | Picolinamide derivatives as TTX-S blockers |
WO2012152741A1 (fr) | 2011-05-10 | 2012-11-15 | Bayer Intellectual Property Gmbh | (thio)carbonylamidines bicycliques |
ES2599752T3 (es) * | 2011-09-29 | 2017-02-03 | Mitsui Chemicals Agro, Inc. | Método de producción de un derivado de 4, 4-difluoro-3,4-dihidroisoquinolina |
EP2762474B1 (fr) * | 2011-09-29 | 2016-02-24 | Mitsui Chemicals Agro, Inc. | Procédé de fabrication de dérivé de 3,4-dihydroisoquinoléine, et corps intermédiaire de cette fabrication |
WO2013080156A1 (fr) | 2011-11-30 | 2013-06-06 | Actelion Pharmaceuticals Ltd | Antibiotiques d'octahydro-2h-pyrido[4,3-e][1,3]oxazin-2-one 3,7-disubstituée |
US9562002B2 (en) | 2013-01-15 | 2017-02-07 | Board Of Regents, The University Of Texas System | STAT3 inhibitor |
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EP0577024B1 (fr) * | 1992-07-01 | 1996-10-16 | Hoechst Aktiengesellschaft | Benzoylguanidines 3,4,5 substituées, procédé pour leur préparation, leur utilisation comme médicament ou agent diagnostique, ainsi que médicament les contenant |
US5968946A (en) * | 1997-10-07 | 1999-10-19 | Ortho-Mcneil Pharmaceutical, Inc. | Heterocyclic derivatives useful in treating central nervous system disorders |
AR045979A1 (es) * | 2003-04-28 | 2005-11-23 | Astrazeneca Ab | Amidas heterociclicas |
TW200526631A (en) * | 2003-10-07 | 2005-08-16 | Renovis Inc | Amide derivatives as ion-channel ligands and pharmaceutical compositions and methods of using the same |
EP1775283A4 (fr) * | 2004-07-14 | 2008-12-10 | Japan Tobacco Inc | Compose 3-aminobenamide et inhibiteur d'activite a recepteur vanilloide 1 (vr1) |
AP2007004119A0 (en) * | 2005-02-28 | 2007-08-31 | Renovis Inc | Amide derivatives as ion-channel ligands and pharmaceutical compositions and methods of using the same |
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2006
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- 2006-02-24 WO PCT/US2006/006615 patent/WO2006093832A2/fr active Application Filing
- 2006-02-24 KR KR1020077022045A patent/KR20070119655A/ko not_active Application Discontinuation
- 2006-02-24 EP EP06736043A patent/EP1853269A4/fr not_active Withdrawn
- 2006-02-24 JP JP2007558085A patent/JP2008531690A/ja active Pending
- 2006-02-24 CA CA002600933A patent/CA2600933A1/fr not_active Abandoned
- 2006-02-24 AU AU2006218824A patent/AU2006218824A1/en not_active Abandoned
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- 2007-02-22 AU AU2007221118A patent/AU2007221118A1/en not_active Abandoned
- 2007-02-22 EP EP07751654A patent/EP1954132A4/fr not_active Withdrawn
- 2007-09-17 NO NO20074739A patent/NO20074739L/no not_active Application Discontinuation
Also Published As
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WO2006093832A2 (fr) | 2006-09-08 |
WO2007100758A3 (fr) | 2007-11-29 |
EP1954132A4 (fr) | 2009-11-04 |
AP2007004119A0 (en) | 2007-08-31 |
EP1853269A2 (fr) | 2007-11-14 |
KR20070119655A (ko) | 2007-12-20 |
EP1853269A4 (fr) | 2011-09-07 |
AU2007221118A1 (en) | 2007-09-07 |
EP1954132A2 (fr) | 2008-08-13 |
WO2007100758A2 (fr) | 2007-09-07 |
AU2006218824A1 (en) | 2006-09-08 |
WO2006093832A3 (fr) | 2007-03-22 |
CA2600933A1 (fr) | 2006-09-08 |
JP2008531690A (ja) | 2008-08-14 |
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