NO20071826L - 1,5-diheterosykel-1H-triazolderivat - Google Patents

1,5-diheterosykel-1H-triazolderivat

Info

Publication number
NO20071826L
NO20071826L NO20071826A NO20071826A NO20071826L NO 20071826 L NO20071826 L NO 20071826L NO 20071826 A NO20071826 A NO 20071826A NO 20071826 A NO20071826 A NO 20071826A NO 20071826 L NO20071826 L NO 20071826L
Authority
NO
Norway
Prior art keywords
diheterosykel
triazole
salt
cox
compound
Prior art date
Application number
NO20071826A
Other languages
English (en)
Inventor
Naoaki Kanaya
Kunihiko Fujii
Original Assignee
Daiichi Seiyaku Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daiichi Seiyaku Co filed Critical Daiichi Seiyaku Co
Publication of NO20071826L publication Critical patent/NO20071826L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Det beskrives en forbindelse representert ved Formel (I): hvor Ar1, Ar2, R1 og R2 hver representerer en substituent, et salt derav, eller et solvat av forbindelsen eller saltet og til en medisin inneholdende samme. Ifølge foreliggende oppfinnelse er det tilveiebrakt et kraftig blodplateaggregeringsundertrykkende middel som ikke hemmer COX-1 og COX-2.
NO20071826A 2004-10-19 2007-04-10 1,5-diheterosykel-1H-triazolderivat NO20071826L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2004303851 2004-10-19
PCT/JP2005/019207 WO2006043594A1 (ja) 2004-10-19 2005-10-19 １，５－ジ複素環－１ｈ－トリアゾール誘導体

Publications (1)

Publication Number Publication Date
NO20071826L true NO20071826L (no) 2007-06-14

Family

ID=36203009

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20071826A NO20071826L (no) 2004-10-19 2007-04-10 1,5-diheterosykel-1H-triazolderivat

Country Status (13)

Country Link
US (1) US20080125409A1 (no)
EP (1) EP1803719A4 (no)
JP (1) JPWO2006043594A1 (no)
KR (1) KR20070063530A (no)
CN (1) CN101039934A (no)
AU (1) AU2005296582A1 (no)
CA (1) CA2583153A1 (no)
IL (1) IL182538A0 (no)
MX (1) MX2007004643A (no)
NO (1) NO20071826L (no)
RU (1) RU2007118659A (no)
WO (1) WO2006043594A1 (no)
ZA (1) ZA200703562B (no)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MXPA05011276A (es) * 2003-04-21 2006-01-24 Daiichi Seiyaku Co Derivado heterociclico de cinco miembros.
JP6767878B2 (ja) 2014-06-06 2020-10-14 リサーチ トライアングル インスティテュート アペリン受容体（ａｐｊ）アゴニストおよびそれらの使用
PE20190258A1 (es) 2015-12-09 2019-02-25 Res Triangle Inst Antagonistas del receptor de la apelina (apj) mejorados y usos de los mismos
KR102541080B1 (ko) * 2016-10-12 2023-06-08 리서치 트라이앵글 인스티튜트 복소환식 아펠린 수용체(apj) 작용제 및 이의 용도
JP2023548353A (ja) * 2020-11-05 2023-11-16 バイエル・アクチエンゲゼルシヤフト 有用植物および作物植物の保護のための毒性緩和剤としての［（１，５－ジヘテロアリール－１ｈ－１，２，４－トリアゾール－３－イル）オキシ］酢酸誘導体

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AUPR878201A0 (en) * 2001-11-09 2001-12-06 Fujisawa Pharmaceutical Co., Ltd. New compounds
WO2004060367A1 (en) * 2002-12-30 2004-07-22 Fujisawa Pharmaceutical Co., Ltd. Imidazole and triazole derivatives useful as selective cox-1 inhibitors
DE602004028800D1 (en) * 2003-02-07 2010-10-07 Daiichi Sankyo Co Ltd Pyrazolderivat
MXPA05011276A (es) * 2003-04-21 2006-01-24 Daiichi Seiyaku Co Derivado heterociclico de cinco miembros.

Also Published As

Publication number Publication date
US20080125409A1 (en) 2008-05-29
CA2583153A1 (en) 2006-04-27
IL182538A0 (en) 2007-09-20
WO2006043594A1 (ja) 2006-04-27
EP1803719A4 (en) 2008-07-02
EP1803719A1 (en) 2007-07-04
CN101039934A (zh) 2007-09-19
RU2007118659A (ru) 2008-11-27
AU2005296582A1 (en) 2006-04-27
KR20070063530A (ko) 2007-06-19
JPWO2006043594A1 (ja) 2008-05-22
MX2007004643A (es) 2007-06-08
ZA200703562B (en) 2008-08-27

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Legal Events

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