NO20070427L - Imidazolvarianter som modulatorer av GABA reseptor for behandlingen av gastrointestinale forstyrrelser - Google Patents
Imidazolvarianter som modulatorer av GABA reseptor for behandlingen av gastrointestinale forstyrrelserInfo
- Publication number
- NO20070427L NO20070427L NO20070427A NO20070427A NO20070427L NO 20070427 L NO20070427 L NO 20070427L NO 20070427 A NO20070427 A NO 20070427A NO 20070427 A NO20070427 A NO 20070427A NO 20070427 L NO20070427 L NO 20070427L
- Authority
- NO
- Norway
- Prior art keywords
- modulators
- treatment
- gastrointestinal disorders
- gaba receptor
- imidazole
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/10—Laxatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nutrition Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE0401653A SE0401653D0 (sv) | 2004-06-24 | 2004-06-24 | New compounds |
| PCT/SE2005/000951 WO2006001750A1 (en) | 2004-06-24 | 2005-06-20 | Imidazole variants as modulators of gaba receptor for the treatment of gi disorders |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20070427L true NO20070427L (no) | 2007-03-26 |
Family
ID=32733683
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20070427A NO20070427L (no) | 2004-06-24 | 2007-01-23 | Imidazolvarianter som modulatorer av GABA reseptor for behandlingen av gastrointestinale forstyrrelser |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US7718686B2 (no) |
| EP (1) | EP1761531A1 (no) |
| JP (1) | JP2008503571A (no) |
| CN (1) | CN1972942A (no) |
| AU (1) | AU2005257706C1 (no) |
| BR (1) | BRPI0512517A (no) |
| CA (1) | CA2570619A1 (no) |
| IL (1) | IL179609A0 (no) |
| MX (1) | MXPA06015034A (no) |
| NO (1) | NO20070427L (no) |
| NZ (1) | NZ551968A (no) |
| RU (1) | RU2389722C2 (no) |
| SE (1) | SE0401653D0 (no) |
| UA (1) | UA87141C2 (no) |
| WO (1) | WO2006001750A1 (no) |
| ZA (1) | ZA200610429B (no) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE0401653D0 (sv) | 2004-06-24 | 2004-06-24 | Astrazeneca Ab | New compounds |
| ATE414703T1 (de) * | 2005-09-19 | 2008-12-15 | Hoffmann La Roche | Isoxazolderivate als inverse gaba a alpha5 agonisten |
| GB0525068D0 (en) | 2005-12-08 | 2006-01-18 | Novartis Ag | Organic compounds |
| KR20080080214A (ko) * | 2005-12-23 | 2008-09-02 | 아스트라제네카 아베 | 헤테로시클릭 ｇａｂａ-ｂ 조절제 |
| CA2632016A1 (en) | 2005-12-23 | 2007-06-28 | Astrazeneca Ab | Imidazole derivatives for the treatment of gastrointestinal disorders |
| EP1968947A1 (en) * | 2005-12-23 | 2008-09-17 | AstraZeneca AB | Gaba-b receptor modulators |
| KR20080090448A (ko) * | 2005-12-23 | 2008-10-08 | 아스트라제네카 아베 | Ｇａｂａ-ｂ 수용체 조절제로서의 이미다졸 |
| CA2632011A1 (en) * | 2005-12-23 | 2007-06-28 | Astrazeneca Ab | Pyrazoles for the treatment of gerd and ibs |
| WO2008104994A2 (en) * | 2007-02-28 | 2008-09-04 | Advinus Therapeutics Private Limited | 2,2,2-tri-substituted acetamide derivatives as glucokinase activators, their process and pharmaceutical application |
| WO2008130313A1 (en) * | 2007-04-18 | 2008-10-30 | Astrazeneca Ab | Imidazole derivatives as modulators of the gaba receptor for the treatment of gastrointestinal disorders |
| US8349852B2 (en) | 2009-01-13 | 2013-01-08 | Novartis Ag | Quinazolinone derivatives useful as vanilloid antagonists |
| WO2011092290A1 (en) | 2010-02-01 | 2011-08-04 | Novartis Ag | Pyrazolo[5,1b]oxazole derivatives as crf-1 receptor antagonists |
| AR080056A1 (es) | 2010-02-01 | 2012-03-07 | Novartis Ag | Derivados de ciclohexil-amida como antagonistas de los receptores de crf |
| WO2011095450A1 (en) | 2010-02-02 | 2011-08-11 | Novartis Ag | Cyclohexyl amide derivatives as crf receptor antagonists |
| US8722731B2 (en) | 2010-06-07 | 2014-05-13 | Novomedix, Llc | Furanyl compounds and the use thereof |
| US8546416B2 (en) | 2011-05-27 | 2013-10-01 | Novartis Ag | 3-spirocyclic piperidine derivatives as ghrelin receptor agonists |
| CA2867043A1 (en) | 2012-05-03 | 2013-11-07 | Novartis Ag | L-malate salt of 2,7-diaza-spiro[4.5]dec-7-yle derivatives and crystalline forms thereof as ghrelin receptor agonists |
| TW201623257A (zh) | 2014-05-09 | 2016-07-01 | 奧利安公司 | 藥理活性之喹唑啉二酮衍生物 |
| CN107922348A (zh) * | 2015-06-22 | 2018-04-17 | 大日本住友制药株式会社 | 双环杂环酰胺衍生物 |
| CA2990583A1 (en) | 2015-06-22 | 2016-12-29 | Sumitomo Dainippon Pharma Co., Ltd. | 1,4-disubstituted imidazole derivative |
| US10898469B2 (en) | 2016-02-26 | 2021-01-26 | Sumitomo Dainippon Pharma Co., Ltd. | Imidazolylamide derivative |
Family Cites Families (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH449046A (de) | 1963-07-09 | 1967-12-31 | Ciba Geigy | Verfahren zur Herstellung neuer Aminosäuren |
| US3876655A (en) * | 1971-08-18 | 1975-04-08 | Beecham Group Ltd | Anti-inflammatory acyl imidazoles |
| US4659720A (en) * | 1982-12-20 | 1987-04-21 | Merck & Co., Inc. | 5-amino or substituted amino imidazoles useful to treat coccidiosis |
| GB8425872D0 (en) | 1984-10-12 | 1984-11-21 | Ciba Geigy Ag | Chemical compounds |
| GB8624879D0 (en) * | 1986-10-17 | 1986-11-19 | May & Baker Ltd | Compositions of matter |
| GB8820266D0 (en) | 1988-08-26 | 1988-09-28 | Smith Kline French Lab | Compounds |
| GB8911017D0 (en) | 1989-05-13 | 1989-06-28 | Ciba Geigy Ag | Substituted aminoalkylphosphinic acids |
| FR2663934B1 (fr) * | 1990-06-27 | 1994-06-03 | Adir | Nouveaux derives de l'acide 4 - amino butyrique, leur procede de preparation et les preparations pharmaceutiques qui les contiennent. |
| US5214063A (en) * | 1990-06-27 | 1993-05-25 | Adir Et Compagnie | 4-aminobutyric acid compounds, compositions and methods of use for treating disorders related to a dysfunction of GABAB receptors |
| DE4213750A1 (de) * | 1992-04-25 | 1993-10-28 | Basf Ag | Verfahren zur Herstellung von 3-(Hydroxyphenyl)-propionaldehyden und gegebenenfalls der Herstellung von 3-(hydroxyphenyl)-propanolen |
| TW270118B (no) * | 1993-02-26 | 1996-02-11 | Schering Corp | |
| FR2722192A1 (fr) | 1994-07-06 | 1996-01-12 | Adir | Nouveaux derives de l'acide 4-amino butyrique, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| WO1997031900A1 (fr) * | 1996-02-29 | 1997-09-04 | Kissei Pharmaceutical Co., Ltd. | Derives d'imidazole et inhibiteur d'epaississement de la paroi vasculaire |
| SE9603408D0 (sv) | 1996-09-18 | 1996-09-18 | Astra Ab | Medical use |
| SE9904508D0 (sv) | 1999-12-09 | 1999-12-09 | Astra Ab | New compounds |
| SE9904507D0 (sv) | 1999-12-09 | 1999-12-09 | Astra Ab | New compounds |
| WO2001090141A2 (en) | 2000-05-25 | 2001-11-29 | Merck Frosst Canada & Co. | Gb1c isoform and nucleotides |
| AU2001273040A1 (en) * | 2000-06-27 | 2002-01-08 | Du Pont Pharmaceuticals Company | Factor xa inhibitors |
| KR20040033048A (ko) * | 2001-09-14 | 2004-04-17 | 미츠비시 웰파마 가부시키가이샤 | 티아졸리딘 유도체 및 이의 약학적 용도 |
| GB0209481D0 (en) | 2002-04-24 | 2002-06-05 | Novartis Ag | Organic compounds |
| SE0401653D0 (sv) | 2004-06-24 | 2004-06-24 | Astrazeneca Ab | New compounds |
| CA2632011A1 (en) * | 2005-12-23 | 2007-06-28 | Astrazeneca Ab | Pyrazoles for the treatment of gerd and ibs |
| EP1968947A1 (en) * | 2005-12-23 | 2008-09-17 | AstraZeneca AB | Gaba-b receptor modulators |
| KR20080090448A (ko) * | 2005-12-23 | 2008-10-08 | 아스트라제네카 아베 | Ｇａｂａ-ｂ 수용체 조절제로서의 이미다졸 |
| CA2632016A1 (en) * | 2005-12-23 | 2007-06-28 | Astrazeneca Ab | Imidazole derivatives for the treatment of gastrointestinal disorders |
| KR20080080214A (ko) * | 2005-12-23 | 2008-09-02 | 아스트라제네카 아베 | 헤테로시클릭 ｇａｂａ-ｂ 조절제 |
| WO2008130314A1 (en) * | 2007-04-18 | 2008-10-30 | Astrazeneca Ab | Xanthine compounds having a positive allosteric gabab receptor modulator effect |
| WO2008130313A1 (en) * | 2007-04-18 | 2008-10-30 | Astrazeneca Ab | Imidazole derivatives as modulators of the gaba receptor for the treatment of gastrointestinal disorders |
-
2004
- 2004-06-24 SE SE0401653A patent/SE0401653D0/xx unknown
-
2005
- 2005-06-20 AU AU2005257706A patent/AU2005257706C1/en not_active Ceased
- 2005-06-20 CN CNA2005800211603A patent/CN1972942A/zh active Pending
- 2005-06-20 WO PCT/SE2005/000951 patent/WO2006001750A1/en active Application Filing
- 2005-06-20 UA UAA200613007A patent/UA87141C2/ru unknown
- 2005-06-20 MX MXPA06015034A patent/MXPA06015034A/es active IP Right Grant
- 2005-06-20 EP EP05754140A patent/EP1761531A1/en not_active Withdrawn
- 2005-06-20 US US11/570,830 patent/US7718686B2/en not_active Expired - Fee Related
- 2005-06-20 BR BRPI0512517-0A patent/BRPI0512517A/pt not_active IP Right Cessation
- 2005-06-20 RU RU2006146871/04A patent/RU2389722C2/ru not_active IP Right Cessation
- 2005-06-20 CA CA002570619A patent/CA2570619A1/en not_active Abandoned
- 2005-06-20 NZ NZ551968A patent/NZ551968A/en unknown
- 2005-06-20 JP JP2007518000A patent/JP2008503571A/ja active Pending
-
2006
- 2006-11-27 IL IL179609A patent/IL179609A0/en unknown
- 2006-12-12 ZA ZA200610429A patent/ZA200610429B/xx unknown
-
2007
- 2007-01-23 NO NO20070427A patent/NO20070427L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| US7718686B2 (en) | 2010-05-18 |
| MXPA06015034A (es) | 2007-02-08 |
| US20080269216A1 (en) | 2008-10-30 |
| NZ551968A (en) | 2010-07-30 |
| WO2006001750A1 (en) | 2006-01-05 |
| AU2005257706A1 (en) | 2006-01-05 |
| CN1972942A (zh) | 2007-05-30 |
| CA2570619A1 (en) | 2006-01-05 |
| AU2005257706C1 (en) | 2009-01-29 |
| BRPI0512517A (pt) | 2008-03-11 |
| JP2008503571A (ja) | 2008-02-07 |
| UA87141C2 (ru) | 2009-06-25 |
| RU2389722C2 (ru) | 2010-05-20 |
| ZA200610429B (en) | 2008-09-25 |
| AU2005257706B2 (en) | 2008-08-21 |
| EP1761531A1 (en) | 2007-03-14 |
| RU2006146871A (ru) | 2008-07-27 |
| SE0401653D0 (sv) | 2004-06-24 |
| IL179609A0 (en) | 2007-05-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |