NO20062688L - 8- [3-Amino-piperidin-1-YL] -Xanthine, Preparation and Use as DPP Inhibitors - Google Patents
8- [3-Amino-piperidin-1-YL] -Xanthine, Preparation and Use as DPP InhibitorsInfo
- Publication number
- NO20062688L NO20062688L NO20062688A NO20062688A NO20062688L NO 20062688 L NO20062688 L NO 20062688L NO 20062688 A NO20062688 A NO 20062688A NO 20062688 A NO20062688 A NO 20062688A NO 20062688 L NO20062688 L NO 20062688L
- Authority
- NO
- Norway
- Prior art keywords
- xanthine
- piperidin
- amino
- preparation
- dpp
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
- C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
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Abstract
Det beskrives substituerte xantiner med den generelle formel (I), hvor R er som definert i patentkrav 1, deres tautomerer, deres stereoisomerer, deres blandinger og deres salter, som oppviser verdifulle farmakologiske egenskaper, spesielt en hemmende virkning på aktiviteten av enzymet dipeptidyl-peptidase-IV (DPP-IV).Substituted xanthines of general formula (I) are described, wherein R is as defined in claim 1, their tautomers, their stereoisomers, their mixtures and their salts, which exhibit valuable pharmacological properties, in particular an inhibitory effect on the activity of the enzyme dipeptidyl peptidase. -IV (DPP-IV).
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE102004008112A DE102004008112A1 (en) | 2004-02-18 | 2004-02-18 | New 8-aminopiperidinyl-xanthine derivatives, useful for treating e.g. diabetes, arthritis and osteoporosis, are inhibitors of dipeptidylpeptidase-IV |
DE102004012921A DE102004012921A1 (en) | 2004-03-17 | 2004-03-17 | New 7-butynyl-8-(3-amino-1-piperidinyl)xanthine derivatives useful as dipeptidyl peptidase IV inhibitors, e.g. for treating diabetes, arthritis, obesity and osteoporosis |
DE102004032263A DE102004032263A1 (en) | 2004-07-03 | 2004-07-03 | New 7-butynyl-8-(3-amino-1-piperidinyl)xanthine derivatives useful as dipeptidyl peptidase IV inhibitors, e.g. for treating diabetes, arthritis, obesity and osteoporosis |
PCT/EP2005/001427 WO2005085246A1 (en) | 2004-02-18 | 2005-02-12 | 8-[3-amino-piperidin-1-yl]-xanthine, the production thereof and the use in the form of a dpp inhibitor |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20062688L true NO20062688L (en) | 2006-09-14 |
Family
ID=34922894
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20062688A NO20062688L (en) | 2004-02-18 | 2006-06-09 | 8- [3-Amino-piperidin-1-YL] -Xanthine, Preparation and Use as DPP Inhibitors |
Country Status (30)
Country | Link |
---|---|
EP (2) | EP2119717B1 (en) |
JP (2) | JP4733058B2 (en) |
KR (1) | KR101207224B1 (en) |
CN (1) | CN102199151A (en) |
AR (1) | AR047614A1 (en) |
AT (1) | ATE430150T1 (en) |
AU (1) | AU2005219508B2 (en) |
BR (1) | BRPI0507873B8 (en) |
CA (1) | CA2555050C (en) |
CY (1) | CY1109284T1 (en) |
DE (1) | DE502005007196D1 (en) |
DK (1) | DK1758905T3 (en) |
EA (2) | EA010854B1 (en) |
EC (1) | ECSP066775A (en) |
ES (1) | ES2326666T3 (en) |
HK (1) | HK1103402A1 (en) |
HR (1) | HRP20090346T1 (en) |
IL (2) | IL176920A (en) |
ME (1) | ME01108B (en) |
MY (1) | MY144322A (en) |
NO (1) | NO20062688L (en) |
NZ (1) | NZ548901A (en) |
PE (1) | PE20060210A1 (en) |
PL (1) | PL1758905T3 (en) |
PT (1) | PT1758905E (en) |
RS (1) | RS50982B (en) |
SI (1) | SI1758905T1 (en) |
TW (1) | TWI350756B (en) |
UY (1) | UY28749A1 (en) |
WO (1) | WO2005085246A1 (en) |
Families Citing this family (86)
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DE102004009039A1 (en) | 2004-02-23 | 2005-09-08 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | 8- [3-Amino-piperidin-1-yl] xanthines, their preparation and use as pharmaceuticals |
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