TH74687A - 8- [3-amino-piperidin-1-il] - xanthine, its preparation and its use as a pharmacological component. - Google Patents
8- [3-amino-piperidin-1-il] - xanthine, its preparation and its use as a pharmacological component.Info
- Publication number
- TH74687A TH74687A TH501000636A TH0501000636A TH74687A TH 74687 A TH74687 A TH 74687A TH 501000636 A TH501000636 A TH 501000636A TH 0501000636 A TH0501000636 A TH 0501000636A TH 74687 A TH74687 A TH 74687A
- Authority
- TH
- Thailand
- Prior art keywords
- xanthine
- piperidin
- amino
- preparation
- pharmacological component
- Prior art date
Links
- LRFVTYWOQMYALW-UHFFFAOYSA-N Xanthine Natural products O=C1NC(=O)NC2=C1NC=N2 LRFVTYWOQMYALW-UHFFFAOYSA-N 0.000 title abstract 5
- 230000000144 pharmacologic effect Effects 0.000 title abstract 3
- 229940075420 xanthine Drugs 0.000 title abstract 3
- 239000000126 substance Substances 0.000 claims abstract 3
- 125000004847 2-fluorobenzyl group Chemical group [H]C1=C([H])C(F)=C(C([H])=C1[H])C([H])([H])* 0.000 claims 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 claims 1
- 150000001875 compounds Chemical class 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 229940079593 drugs Drugs 0.000 claims 1
- 102000016622 Dipeptidyl Peptidase 4 Human genes 0.000 abstract 3
- 101700062901 DPP Proteins 0.000 abstract 2
- CDAISMWEOUEBRE-GPIVLXJGSA-N Inositol Chemical compound O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@H](O)[C@@H]1O CDAISMWEOUEBRE-GPIVLXJGSA-N 0.000 abstract 2
- 229960000367 Inositol Drugs 0.000 abstract 2
- 230000002401 inhibitory effect Effects 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 239000011780 sodium chloride Substances 0.000 abstract 2
- 239000000758 substrate Substances 0.000 abstract 2
- 230000024881 catalytic activity Effects 0.000 abstract 1
Abstract
DC60 (16/05/48) การประดิษฐ์นี้ เกี่ยวกับซับสทิทิวเทดแซนธีนของสูตรทั่วไป (สูตรเคมี) (I), ซึ่ง R นิยามตามข้อถือสิทธิข้อ 1 ทอโทเมอร์, สเตอรีโอไอโซเมอร์, ของผสมของมัน และ เกลือของมัน, ซึ่งมีสมบัติเภสัชวิทยาที่มีค่า, โดยเฉพาะ ผลในการยับยั้งแอคติวิตีของเอนไซม์ได เปปทิดิลเปปทิเดส-IV (DPP-IV) การประดิษฐ์นี้ เกี่ยวกับซับสทิทิวเทดแซนธีนของสูตรทั่วไป (สูตรเคมี) (I), ซึ่ง R นิยามตามข้อถือสิทธิข้อ 1 ทอโทเมอร์, สเตอรีโอไอโซเมอร์, ของผสมของมัน และ เกลือของมัน , ซึ่งมีสมบัติเภสัชวิทยาที่มีค่า, โดยเฉพาะ ผลในการยับยั้งแอคติวิตีของเอน ไซม์ได เปปทิดิลเปปทิเดส -IV (DPP-IV) สิทธิบัตรยา DC60 (16/05/48) invention of this Regarding the substrate of xanthine of the general formula (chemical formula) (I), which R is defined in Clause 1, inositol, stereosomer, mixtures. Its and its salts, which have valuable pharmacological properties, are especially effective in inhibiting the enzyme activity. Peptidil Peptidase-IV (DPP-IV). Regarding the substrate of xanthine of the general formula (chemical formula) (I), which R is defined in Clause 1, inositol, stereosomer, mixtures. Its and its salts, which have valuable pharmacological properties, in particular the inhibitory effect of the enzyme dipeptidyl peptidase-IV (DPP-IV).
Claims (1)
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TH74687A true TH74687A (en) | 2006-01-19 |
Family
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