NO20062198L - Bradykinin B1 reseptorantagonister - Google Patents

Bradykinin B1 reseptorantagonister

Info

Publication number
NO20062198L
NO20062198L NO20062198A NO20062198A NO20062198L NO 20062198 L NO20062198 L NO 20062198L NO 20062198 A NO20062198 A NO 20062198A NO 20062198 A NO20062198 A NO 20062198A NO 20062198 L NO20062198 L NO 20062198L
Authority
NO
Norway
Prior art keywords
bradykinin
receptor antagonists
peptides
conjugated peptides
present
Prior art date
Application number
NO20062198A
Other languages
English (en)
Inventor
Thomas Storz
Yue Li
Amico Derin C D
Gordon Ng
Colin V Gegg
Jr Benny C Askew
Yuelie Lu
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amgen Inc filed Critical Amgen Inc
Publication of NO20062198L publication Critical patent/NO20062198L/no

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/043—Kallidins; Bradykinins; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10—Peptides having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A—HUMAN NECESSITIES
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    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/18—Kallidins; Bradykinins; Related peptides

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Epidemiology (AREA)
  • Neurology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biomedical Technology (AREA)
  • Dermatology (AREA)
  • Virology (AREA)
  • Neurosurgery (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Diabetes (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Addiction (AREA)
  • Endocrinology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Communicable Diseases (AREA)

Abstract

Foreliggende oppfinnelse vedrører visse biologisk aktive peptider og konjugerte peptider som kan anvendes terapeutisk eller profylaktisk mot sykdommer eller tilstander forbundet med BI som det forårsakende middel. I en foretrukket utførelessform av oppfinnelsen blir biologisk aktive PEG-konjugerte peptider tilveiebrakt. I et aspekt av foreliggende oppfinnelse er farmasøytisk aktive PEG-konjugerte peptider ifølge oppfinnelsen anvendelige for å behandle inflammasjon eller smerte.
NO20062198A 2003-10-22 2006-05-15 Bradykinin B1 reseptorantagonister NO20062198L (no)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US51391303P 2003-10-22 2003-10-22
US53892904P 2004-01-24 2004-01-24
US10/972,236 US7605120B2 (en) 2003-10-22 2004-10-21 Antagonists of the brandykinin B1 receptor
PCT/US2004/034976 WO2005042027A2 (en) 2003-10-22 2004-10-22 Antagonists of the bradykinin b1 receptor

Publications (1)

Publication Number Publication Date
NO20062198L true NO20062198L (no) 2006-07-18

Family

ID=34990807

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20062198A NO20062198L (no) 2003-10-22 2006-05-15 Bradykinin B1 reseptorantagonister

Country Status (15)

Country Link
US (4) US7605120B2 (no)
EP (1) EP1677830B1 (no)
JP (1) JP4896728B2 (no)
KR (2) KR20060105757A (no)
AU (1) AU2004285467A1 (no)
BR (1) BRPI0415755A (no)
CA (1) CA2545499A1 (no)
EA (1) EA009294B1 (no)
EC (1) ECSP066575A (no)
ES (1) ES2395546T3 (no)
IL (1) IL175084A0 (no)
MA (1) MA28160A1 (no)
NO (1) NO20062198L (no)
SG (1) SG149872A1 (no)
WO (1) WO2005042027A2 (no)

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DE102011118029A1 (de) * 2011-06-20 2012-12-20 Universität Leipzig Modifizierte antibiotische Peptide mit variabler systemischer Freisetzung
US9884067B2 (en) 2013-03-14 2018-02-06 University Of Maryland, Baltimore Androgen receptor down-regulating agents and uses thereof
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US11401303B2 (en) * 2020-06-15 2022-08-02 Taian City Qihang Biotechnology Co. Synthetic peptide BRAP and application in preparation of anti-inflammatory drug for COVID-19 thereof
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Also Published As

Publication number Publication date
KR20060105757A (ko) 2006-10-11
US20090137452A1 (en) 2009-05-28
WO2005042027A2 (en) 2005-05-12
MA28160A1 (fr) 2006-09-01
US8288351B2 (en) 2012-10-16
AU2004285467A2 (en) 2005-05-12
EP1677830A2 (en) 2006-07-12
JP4896728B2 (ja) 2012-03-14
US7605120B2 (en) 2009-10-20
KR20080015054A (ko) 2008-02-15
WO2005042027A3 (en) 2006-02-09
US20090137483A1 (en) 2009-05-28
IL175084A0 (en) 2006-08-20
CA2545499A1 (en) 2005-05-12
BRPI0415755A (pt) 2006-12-19
JP2007526240A (ja) 2007-09-13
US20050215470A1 (en) 2005-09-29
AU2004285467A1 (en) 2005-05-12
ES2395546T3 (es) 2013-02-13
EP1677830B1 (en) 2012-10-17
KR100860654B1 (ko) 2008-09-26
EA200600817A1 (ru) 2006-12-29
SG149872A1 (en) 2009-02-27
US20090048149A1 (en) 2009-02-19
ECSP066575A (es) 2006-10-17
US8278280B2 (en) 2012-10-02
EA009294B1 (ru) 2007-12-28

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