NO20062137L - Krystallinske former av [+] og [-]-erytro-meflokinhydroklorid - Google Patents

Krystallinske former av [+] og [-]-erytro-meflokinhydroklorid

Info

Publication number
NO20062137L
NO20062137L NO20062137A NO20062137A NO20062137L NO 20062137 L NO20062137 L NO 20062137L NO 20062137 A NO20062137 A NO 20062137A NO 20062137 A NO20062137 A NO 20062137A NO 20062137 L NO20062137 L NO 20062137L
Authority
NO
Norway
Prior art keywords
erythromefloquine
hydrochloride
crystalline forms
forms
cuboids
Prior art date
Application number
NO20062137A
Other languages
English (en)
Inventor
Andrew Douglas Baxter
Kenneth Walter Sinden
Martin Szelagiewicz
Rolf Hilfiker
Original Assignee
Arakis Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Arakis Ltd filed Critical Arakis Ltd
Publication of NO20062137L publication Critical patent/NO20062137L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/06—Antimalarials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Transplantation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

(+) eller (-)-erytro-meflokinhydroklorid kan eksistere i fire krystallinske former A, B, C og D, hvorav form A er den mest stabile form. Form A kan produseres direkte i morfologiske former så som tykke søyler, kuboider, kuber og kube-lignende former, som lett kan håndteres under prosessering og formulering. (+)- eller (-)-erytro-meflokinhydroklorid danner også solvater med aceton, metyletylketon og tetrahydrofuran.
NO20062137A 2003-12-17 2006-05-12 Krystallinske former av [+] og [-]-erytro-meflokinhydroklorid NO20062137L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0329236.4A GB0329236D0 (en) 2003-12-17 2003-12-17 Crystalline forms of (+)- and (-)- erthro-mefloquine hydrochloride
PCT/GB2004/005331 WO2005058872A1 (en) 2003-12-17 2004-12-17 Crystalline forms of (+)- and (-)-erythro-mefloquine hydrochloride

Publications (1)

Publication Number Publication Date
NO20062137L true NO20062137L (no) 2006-09-11

Family

ID=30471226

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20062137A NO20062137L (no) 2003-12-17 2006-05-12 Krystallinske former av [+] og [-]-erytro-meflokinhydroklorid

Country Status (13)

Country Link
US (1) US20070078161A1 (no)
EP (1) EP1753741A1 (no)
JP (1) JP2007513196A (no)
KR (1) KR20060126985A (no)
CN (1) CN1882566A (no)
AU (1) AU2004299340B2 (no)
CA (1) CA2543076A1 (no)
GB (1) GB0329236D0 (no)
IL (1) IL174969A0 (no)
MX (1) MXPA06006751A (no)
NO (1) NO20062137L (no)
WO (1) WO2005058872A1 (no)
ZA (1) ZA200603075B (no)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0406014D0 (en) * 2004-03-17 2004-04-21 Arakis Ltd Pharmaceutical composition and use
US20140012013A1 (en) * 2011-03-17 2014-01-09 Shionogi & Co., Ltd. Method for producing pyrazole carboxylic acid derivative
ES2639052T3 (es) * 2011-09-07 2017-10-25 Teva Pharmaceuticals International Gmbh Forma polimórfica de hidrocloruro de pridopidina

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE55387T1 (de) * 1983-10-07 1990-08-15 Hoffmann La Roche Mefloquin-hydrochlorid.
ATE210655T1 (de) * 1992-01-31 2001-12-15 Hoffmann La Roche Asymmetrische hydrierung

Also Published As

Publication number Publication date
EP1753741A1 (en) 2007-02-21
AU2004299340B2 (en) 2008-11-13
US20070078161A1 (en) 2007-04-05
IL174969A0 (en) 2006-08-20
ZA200603075B (en) 2007-07-25
WO2005058872A1 (en) 2005-06-30
GB0329236D0 (en) 2004-01-21
KR20060126985A (ko) 2006-12-11
AU2004299340A1 (en) 2005-06-30
MXPA06006751A (es) 2006-08-31
JP2007513196A (ja) 2007-05-24
CA2543076A1 (en) 2005-06-30
CN1882566A (zh) 2006-12-20

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