NO20061117L - Metode for syntese av 3-(3-Fluor-4-hydroksyfenyl)-7-hydroksynaftonitril - Google Patents

Metode for syntese av 3-(3-Fluor-4-hydroksyfenyl)-7-hydroksynaftonitril

Info

Publication number
NO20061117L
NO20061117L NO20061117A NO20061117A NO20061117L NO 20061117 L NO20061117 L NO 20061117L NO 20061117 A NO20061117 A NO 20061117A NO 20061117 A NO20061117 A NO 20061117A NO 20061117 L NO20061117 L NO 20061117L
Authority
NO
Norway
Prior art keywords
hydroxynaphthonitrile
hydroxyphenyl
fluoro
synthesis
preparing
Prior art date
Application number
NO20061117A
Other languages
English (en)
Inventor
Panolil Raveendranath
Karen Wiggins Sutherland
Yanzhong Wu
Jianxin Ren
Mousumi Ghosh
Mahmut Levent
Original Assignee
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34312297&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO20061117(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Wyeth Corp filed Critical Wyeth Corp
Publication of NO20061117L publication Critical patent/NO20061117L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/49—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C255/54—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and etherified hydroxy groups bound to the carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C253/00—Preparation of carboxylic acid nitriles
    • C07C253/30—Preparation of carboxylic acid nitriles by reactions not involving the formation of cyano groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/49—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C255/53—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and hydroxy groups bound to the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C37/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring
    • C07C37/01—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by replacing functional groups bound to a six-membered aromatic ring by hydroxy groups, e.g. by hydrolysis
    • C07C37/055—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by replacing functional groups bound to a six-membered aromatic ring by hydroxy groups, e.g. by hydrolysis the substituted group being bound to oxygen, e.g. ether group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C41/00—Preparation of ethers; Preparation of compounds having groups, groups or groups
    • C07C41/01—Preparation of ethers
    • C07C41/18—Preparation of ethers by reactions not forming ether-oxygen bonds
    • C07C41/24—Preparation of ethers by reactions not forming ether-oxygen bonds by elimination of halogens, e.g. elimination of HCl

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Rheumatology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Fremgangsmåte for fremstilling av en forbindelse med formel I hvor R1er CN, F eller Cl; R2 er H eller Br; og R3 og R4 er hver uavhengig H eller F. Disse forbindelser er anvendelige ved behandling av kronisk inflammatoriske sykdommer, så som revmatoid artritt.
NO20061117A 2003-09-09 2006-03-08 Metode for syntese av 3-(3-Fluor-4-hydroksyfenyl)-7-hydroksynaftonitril NO20061117L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US50170003P 2003-09-09 2003-09-09
PCT/US2004/028645 WO2005026105A2 (en) 2003-09-09 2004-09-02 Process for the synthesis of 3-(3-fluoro-4-hydroxyphenyl)-7-hydroxynaphthonitrile

Publications (1)

Publication Number Publication Date
NO20061117L true NO20061117L (no) 2006-03-22

Family

ID=34312297

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20061117A NO20061117L (no) 2003-09-09 2006-03-08 Metode for syntese av 3-(3-Fluor-4-hydroksyfenyl)-7-hydroksynaftonitril

Country Status (26)

Country Link
US (1) US7557237B2 (no)
EP (1) EP1663929A2 (no)
JP (1) JP2007505119A (no)
KR (1) KR20060088876A (no)
CN (1) CN1894185A (no)
AR (1) AR045613A1 (no)
AU (1) AU2004272571A1 (no)
BR (1) BRPI0413724A (no)
CA (1) CA2536768A1 (no)
CO (1) CO5670331A2 (no)
CR (1) CR8263A (no)
EC (1) ECSP066416A (no)
GT (1) GT200400179A (no)
IL (1) IL173922A0 (no)
MX (1) MXPA06002450A (no)
NI (1) NI200600063A (no)
NO (1) NO20061117L (no)
NZ (1) NZ569134A (no)
PA (1) PA8611901A1 (no)
PE (1) PE20050947A1 (no)
RU (1) RU2006105916A (no)
SG (1) SG146646A1 (no)
TW (1) TW200510280A (no)
UA (1) UA84166C2 (no)
WO (1) WO2005026105A2 (no)
ZA (1) ZA200601986B (no)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104114521A (zh) 2012-02-17 2014-10-22 旭硝子株式会社 含氟芳香族化合物及其制造方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5554621A (en) 1995-06-07 1996-09-10 Bristol-Myers Squibb Company Dihydropyridine NPY antagonists: nitrogen heterocyclic derivatives
WO1998011040A1 (en) 1996-09-13 1998-03-19 Albemarle Corporation Production of 6-bromo-2-naphthol and derivatives
US5840996A (en) 1997-05-08 1998-11-24 Albemarle Corporation Production of brominated methoxynaphthalene compounds
US6914074B2 (en) 2001-12-13 2005-07-05 Wyeth Substituted phenyl naphthalenes as estrogenic agents

Also Published As

Publication number Publication date
GT200400179A (es) 2005-04-18
JP2007505119A (ja) 2007-03-08
MXPA06002450A (es) 2006-06-20
US20050054870A1 (en) 2005-03-10
NZ569134A (en) 2009-10-30
UA84166C2 (ru) 2008-09-25
BRPI0413724A (pt) 2006-10-17
ECSP066416A (es) 2006-09-18
TW200510280A (en) 2005-03-16
WO2005026105A3 (en) 2005-06-23
CO5670331A2 (es) 2006-08-31
NI200600063A (es) 2006-06-21
PA8611901A1 (es) 2006-06-02
WO2005026105A2 (en) 2005-03-24
RU2006105916A (ru) 2007-10-20
US7557237B2 (en) 2009-07-07
EP1663929A2 (en) 2006-06-07
CN1894185A (zh) 2007-01-10
CR8263A (es) 2006-10-06
AU2004272571A1 (en) 2005-03-24
IL173922A0 (en) 2006-07-05
SG146646A1 (en) 2008-10-30
CA2536768A1 (en) 2005-03-24
PE20050947A1 (es) 2005-12-13
AR045613A1 (es) 2005-11-02
ZA200601986B (en) 2009-09-30
KR20060088876A (ko) 2006-08-07

Similar Documents

Publication Publication Date Title
NO20072872L (no) Kjemisk prosess
NO20050065L (no) Kjemiske forbindelser
TW200624421A (en) Method for preparing n-phenylpyrazole-1-carboxamides
NO20062517L (no) 2-cyanopyrrolidinkarboksamidforbindelse
NO20064669L (no) Dipeptidylpeptidaseinhibitorer
HK1081543A1 (en) Process for preparing 5-(1,3-oxazol-2-yl) benzoic acid derivatives
BG108650A (en) Azabicyclic-substituted fused-heteroaryl compounds for the treatment of disease
NO20053890L (no) Syntese av 4-amino-2-butenolklorider og anvendelse derav for fremstilling av 3-cyanokinoliner
CY1106969T1 (el) Αναστολεις dpp-iv
NO20062021L (no) Omleirede pentanoler, fremgangsmpte for fremstilling av dette, og deres anvendelse som antiflogistika
EA200100826A1 (ru) 16-галогенопроизводные эпотилона, способ их получения и их применение в фармацевтике
EP1740559A4 (en) 1,3,5-SUBSTITUTED PHENYL DERIVATIVES USEFUL AS INHIBITORS OF BETA-SECRETASE FOR THE TREATMENT OF ALZHEIMER'S DISEASE
NO20052796L (no) Indolylpyrazinonderivater anvendelige for behandling av hyper-proliferative forstyrrelser og sykdommer assosiert med angiogenese
NO20065178L (no) Tienopyridinderivater
DK1104431T3 (da) Metallocenyl-phthalocyaniner
EP1807396A4 (en) 2-AMINOPYRIDINE COMPOUNDS USEFUL AS INHIBITORS OF BETA-SECRETASE FOR THE TREATMENT OF ALZHEIMER'S DISEASE
NO20062629L (no) Oksazolderivater av tetrackliner
NO20055694L (no) Fremgangsmate for fremstilling av (4-hydroksy-6-oksotetrahydropyran-2-yl)acetonitril og derivater derav
NO20055750L (no) Nye kjemiske forbindelser
HUP0302923A2 (hu) Eljárás indol-karbazol-származékok glikozidálására fázisátvivő katalizátorral
NO20064012L (no) Kjemisk prosess
NO20072060L (no) 2-acylaminotiazolderivater
MX2008001778A (es) Combinacion de un agente hipnotico y un compuesto de bis arilo y heteroarilo sustituido y aplicacion terapeutica de la misma.
NO20050885D0 (no) Ny fremgangsmate for syntesen av 1,3-dihydro-2H-3-benzazepin-2-onforbindelser, og anvendelse i syntesen av ivabradin og addisjonssalter derav med en farmasoytisk akseptabel syre
EA200801123A1 (ru) Производные 6-гетероарилпиридоиндолона, способ их получения и применение их в терапии

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application