NO20060279L - Thienopyridonderivater som kinaseinhibitorer - Google Patents

Thienopyridonderivater som kinaseinhibitorer

Info

Publication number
NO20060279L
NO20060279L NO20060279A NO20060279A NO20060279L NO 20060279 L NO20060279 L NO 20060279L NO 20060279 A NO20060279 A NO 20060279A NO 20060279 A NO20060279 A NO 20060279A NO 20060279 L NO20060279 L NO 20060279L
Authority
NO
Norway
Prior art keywords
kinase inhibitors
thienopyridone derivatives
derivatives
thienopyridone
inhibitors
Prior art date
Application number
NO20060279A
Other languages
English (en)
Inventor
Jeremy Martin Davis
Daniel Christopher Brookings
Barry John Langham
Original Assignee
Celltech R&D Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0314492A external-priority patent/GB0314492D0/en
Priority claimed from GB0329485A external-priority patent/GB0329485D0/en
Application filed by Celltech R&D Ltd filed Critical Celltech R&D Ltd
Publication of NO20060279L publication Critical patent/NO20060279L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

En serie av tieno[2,3-b]pyridin-6(7H)-on-derivater, substituert i 2-stillingen med en karbonyl- eller sulfonyl-kjedet pyrrolidin-1-yl eller beslektet gruppe er inhibitorer av p38 MAP-kinase, og er følgelig anvendbare innen medisin, for eksempel ved behandling og/eller forhindring av immun- eller inflammatoriske sykdommer
NO20060279A 2003-06-20 2006-01-19 Thienopyridonderivater som kinaseinhibitorer NO20060279L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0314492A GB0314492D0 (en) 2003-06-20 2003-06-20 Chemical compounds
GB0329485A GB0329485D0 (en) 2003-12-19 2003-12-19 Chemical compounds
PCT/GB2004/002621 WO2004113347A1 (en) 2003-06-20 2004-06-18 Thienopyridone derivatives as kinase inhibitors

Publications (1)

Publication Number Publication Date
NO20060279L true NO20060279L (no) 2006-03-20

Family

ID=33542685

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20060279A NO20060279L (no) 2003-06-20 2006-01-19 Thienopyridonderivater som kinaseinhibitorer

Country Status (12)

Country Link
US (1) US7521460B2 (no)
EP (1) EP1641804A1 (no)
JP (1) JP2007516161A (no)
KR (1) KR20060021905A (no)
AU (1) AU2004249495A1 (no)
BR (1) BRPI0410653A (no)
CA (1) CA2528602A1 (no)
EA (1) EA010297B1 (no)
IL (1) IL172132A0 (no)
MX (1) MXPA05013227A (no)
NO (1) NO20060279L (no)
WO (1) WO2004113347A1 (no)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0214268D0 (en) * 2002-06-20 2002-07-31 Celltech R&D Ltd Chemical compounds
GB0218800D0 (en) * 2002-08-13 2002-09-18 Celltech R&D Ltd Chemical compounds
US20060247269A1 (en) * 2003-06-20 2006-11-02 Brookings Daniel C Thienopyridone derivatives as kinase inhibitors
US7795256B2 (en) * 2003-10-24 2010-09-14 Ucb Pharma S.A. Thieno-pyridinone derivatives as kinase inhibitors
RS53599B1 (en) 2005-05-10 2015-02-27 Intermune, Inc. PIRIDON DERIVATIVES FOR STRESS MODULATION OF ACTIVATED PROTEIN KINASE SYSTEMS
EP1934174B1 (en) * 2005-10-07 2011-04-06 Exelixis, Inc. Azetidines as mek inhibitors for the treatment of proliferative diseases
AU2006318428A1 (en) * 2005-11-23 2007-05-31 Intermune, Inc. Method of modulating stress-activated protein kinase system
GB0601962D0 (en) 2006-01-31 2006-03-15 Ucb Sa Therapeutic agents
US8633201B2 (en) 2006-04-07 2014-01-21 Boehringer Ingelheim International Gmbh Thienopyrimidines having Mnk1/Mnk2 inhibiting activity for pharmaceutical compositions
EP1889847A1 (en) 2006-07-10 2008-02-20 DeveloGen Aktiengesellschaft Pyrrolopyrimidines for pharmaceutical compositions
WO2008064829A2 (en) * 2006-11-30 2008-06-05 Ucb Pharma, S.A. Novel aminothienopyridinone derivatives processes for preparing them and pharmaceutical compositions thereof
US7999006B2 (en) * 2006-12-14 2011-08-16 Exelixis, Inc. Methods of using MEK inhibitors
WO2008124085A2 (en) * 2007-04-03 2008-10-16 Exelixis, Inc. Methods of using combinations of mek and jak-2 inhibitors
GB0714384D0 (en) 2007-07-23 2007-09-05 Ucb Pharma Sa theraputic agents
WO2009093008A1 (en) 2008-01-21 2009-07-30 Ucb Pharma S.A. Thieno-pyridine derivatives as mek inhibitors
ES2567283T3 (es) 2008-06-03 2016-04-21 Intermune, Inc. Compuestos y métodos para tratar trastornos inflamatorios y fibróticos
GB0811304D0 (en) 2008-06-19 2008-07-30 Ucb Pharma Sa Therapeutic agents
KR20110045019A (ko) 2008-08-26 2011-05-03 베링거 인겔하임 인터내셔날 게엠베하 약제학적 조성물을 위한 티에노피리미딘
UY33241A (es) 2010-02-26 2011-09-30 Boehringer Ingelheim Int ?Tienopirimidinas que contienen heterocicloalquilo para composiciones farmacéuticas?.
EP2539343B1 (en) 2010-02-26 2015-12-30 Evotec International GmbH Thienopyrimidines containing a substituted alkyl group for pharmaceutical compositions
EP2539345B1 (en) 2010-02-26 2015-07-22 Boehringer Ingelheim International GmbH 4-[cycloalkyloxy(hetero)arylamino]-thieno[2,3-d]pyrimidines having mnk1/ mnk2 inhibiting activity for pharmaceutical compositions
CA2806670A1 (en) 2010-07-26 2012-02-09 Biomatrica, Inc. Compositions for stabilizing dna, rna and proteins in blood and other biological samples during shipping and storage at ambient temperatures
CA2806734A1 (en) 2010-07-26 2012-02-09 Biomatrica, Inc. Compositions for stabilizing dna, rna and proteins in saliva and other biological samples during shipping and storage at ambient temperatures
AR092742A1 (es) 2012-10-02 2015-04-29 Intermune Inc Piridinonas antifibroticas
MX2015004660A (es) 2012-10-12 2015-08-07 Exelixis Inc Proceso novedoso para la elaboración de compuestos para su uso en el tratamiento del cáncer.
ES2916805T3 (es) * 2012-11-21 2022-07-06 Zoetis Services Llc Síntesis de derivados de isoxazolina espirocíclicos
EP2934572A4 (en) 2012-12-20 2016-11-23 Biomatrica Inc FORMULATIONS AND METHODS FOR STABILIZING PCR REAGENTS
US20160135446A1 (en) 2013-06-13 2016-05-19 Biomatrica, Inc. Cell stabilization
CN110452216B (zh) 2014-04-02 2022-08-26 英特穆恩公司 抗纤维化吡啶酮类
WO2015191632A1 (en) 2014-06-10 2015-12-17 Biomatrica, Inc. Stabilization of thrombocytes at ambient temperatures
ES2946184T3 (es) 2015-12-08 2023-07-13 Biomatrica Inc Reducción de la velocidad de eritrosedimentación

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6048863A (en) * 1994-04-19 2000-04-11 Takeda Chemical Industries, Ltd. Condensed-ring thiophene derivatives and thienopyrimidine derivatives, their production and use
EP1086085A1 (en) * 1998-06-12 2001-03-28 Vertex Pharmaceuticals Incorporated INHIBITORS OF p38
GB0124848D0 (en) 2001-10-16 2001-12-05 Celltech R&D Ltd Chemical compounds
GB0214268D0 (en) * 2002-06-20 2002-07-31 Celltech R&D Ltd Chemical compounds
GB0218800D0 (en) * 2002-08-13 2002-09-18 Celltech R&D Ltd Chemical compounds
US20060247269A1 (en) * 2003-06-20 2006-11-02 Brookings Daniel C Thienopyridone derivatives as kinase inhibitors
US7795256B2 (en) * 2003-10-24 2010-09-14 Ucb Pharma S.A. Thieno-pyridinone derivatives as kinase inhibitors

Also Published As

Publication number Publication date
EA200600064A1 (ru) 2006-08-25
KR20060021905A (ko) 2006-03-08
JP2007516161A (ja) 2007-06-21
AU2004249495A1 (en) 2004-12-29
IL172132A0 (en) 2006-04-10
US7521460B2 (en) 2009-04-21
CA2528602A1 (en) 2004-12-29
WO2004113347A1 (en) 2004-12-29
US20070099894A1 (en) 2007-05-03
MXPA05013227A (es) 2006-03-09
EP1641804A1 (en) 2006-04-05
BRPI0410653A (pt) 2006-07-04
EA010297B1 (ru) 2008-08-29

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