NO20055367L - Kombinasjoner som innbefatter paroksetin og 2-(S)-4-fluor-2-metyl-fenyl)-piperazin-1-karboksylsyer (1-(R)-(3,5-bis-trifluor-2-metyl-fenyl)-etyl]metylamid for behandling av depresjon og/eller angst - Google Patents

Kombinasjoner som innbefatter paroksetin og 2-(S)-4-fluor-2-metyl-fenyl)-piperazin-1-karboksylsyer (1-(R)-(3,5-bis-trifluor-2-metyl-fenyl)-etyl]metylamid for behandling av depresjon og/eller angst

Info

Publication number
NO20055367L
NO20055367L NO20055367A NO20055367A NO20055367L NO 20055367 L NO20055367 L NO 20055367L NO 20055367 A NO20055367 A NO 20055367A NO 20055367 A NO20055367 A NO 20055367A NO 20055367 L NO20055367 L NO 20055367L
Authority
NO
Norway
Prior art keywords
phenyl
methyl
combinations
anxiety
piperazine
Prior art date
Application number
NO20055367A
Other languages
English (en)
Inventor
Mauro Corsi
Sergio Melotto
Renzo Carletti
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of NO20055367L publication Critical patent/NO20055367L/no

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Neurology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Forehggende oppfirmelse angår terapeutiske kombinasjoner som irmbefatter paroksetin eller fysiologisk akseptable salter eller solvater derav og 2-(S)-(4-fluor-2-metyIfenyl)-piperazin-l-karboksylsyre [1-(R)- (3,5-bis-trifluormetyl-fenyl)-etyl]-metyl-amid eller fysiologisk akseptable salter eller solvater derav, farmasøytiske sammensetninger som irmeholder nevnte kombinasjoner og deres anvendelse ved behandling av depresjon og/eller angst.
NO20055367A 2003-04-17 2005-11-14 Kombinasjoner som innbefatter paroksetin og 2-(S)-4-fluor-2-metyl-fenyl)-piperazin-1-karboksylsyer (1-(R)-(3,5-bis-trifluor-2-metyl-fenyl)-etyl]metylamid for behandling av depresjon og/eller angst NO20055367L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0308968.7A GB0308968D0 (en) 2003-04-17 2003-04-17 Medicaments
PCT/EP2004/004126 WO2004091624A1 (en) 2003-04-17 2004-04-16 Combinations comprising paroxetine and 2- (s) - (4-fluoro-2-methyl-phenyl) -piperazine-1-carboxylic acid [1- (r)- (3,5-bis-trifluoro-2-methyl-phenyl) -ethyl]-methyl amide for treatment of depression and/or anxiety

Publications (1)

Publication Number Publication Date
NO20055367L true NO20055367L (no) 2005-11-14

Family

ID=9956996

Family Applications (2)

Application Number Title Priority Date Filing Date
NO20055368A NO20055368L (no) 2003-04-17 2005-11-14 Kombinasjoner av paroksetin og 4-(S)-(4-acetyl-piperazin-1-yl-)-2-(R)-(4-trifluor-2-metyl-fenyl)-piperidin-1-karboksylsyre{1\\[1-(R)-3,5-bis-trifluormetyl-fenyl)-etyl]metylamid for behandling av depresjon og/eller angst
NO20055367A NO20055367L (no) 2003-04-17 2005-11-14 Kombinasjoner som innbefatter paroksetin og 2-(S)-4-fluor-2-metyl-fenyl)-piperazin-1-karboksylsyer (1-(R)-(3,5-bis-trifluor-2-metyl-fenyl)-etyl]metylamid for behandling av depresjon og/eller angst

Family Applications Before (1)

Application Number Title Priority Date Filing Date
NO20055368A NO20055368L (no) 2003-04-17 2005-11-14 Kombinasjoner av paroksetin og 4-(S)-(4-acetyl-piperazin-1-yl-)-2-(R)-(4-trifluor-2-metyl-fenyl)-piperidin-1-karboksylsyre{1\\[1-(R)-3,5-bis-trifluormetyl-fenyl)-etyl]metylamid for behandling av depresjon og/eller angst

Country Status (18)

Country Link
US (4) US20060241124A1 (no)
EP (4) EP1615641A1 (no)
JP (4) JP2006523652A (no)
KR (2) KR20060003876A (no)
CN (2) CN1809355A (no)
AU (2) AU2004229179A1 (no)
BR (2) BRPI0409377A (no)
CA (2) CA2522313A1 (no)
CO (1) CO5700753A2 (no)
GB (1) GB0308968D0 (no)
IS (2) IS8129A (no)
MA (2) MA27731A1 (no)
MX (2) MXPA05011064A (no)
NO (2) NO20055368L (no)
PL (2) PL377858A1 (no)
RU (2) RU2005135647A (no)
WO (4) WO2004091624A1 (no)
ZA (2) ZA200508067B (no)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0203020D0 (en) 2002-02-08 2002-03-27 Glaxo Group Ltd Chemical compounds
GB0403149D0 (en) * 2004-02-12 2004-03-17 Glaxo Group Ltd Medicament
GB0409098D0 (en) * 2004-04-23 2004-05-26 Glaxo Group Ltd Medicament
GB0426942D0 (en) * 2004-12-08 2005-01-12 Glaxo Group Ltd Medicament
WO2007012968A2 (en) * 2005-07-29 2007-02-01 Aurobindo Pharma Ltd Stable dosage form of an antidepressant
GB0621229D0 (en) * 2006-10-20 2006-12-06 Glaxo Group Ltd Novel use
EP2129381A1 (en) 2007-01-24 2009-12-09 Glaxo Group Limited Pharmaceutical compositions comprising 3, 5-diamin0-6- (2, 3-dichl0phenyl) -l, 2, 4-triazine or r (-) -2, 4-diamino-5- (2, 3-dichlorophenyl) -6-fluoromethyl pyrimidine and an nk1
WO2012175434A1 (en) * 2011-06-20 2012-12-27 Glaxo Group Limited Pharmaceutical formulations comprising vestipitant
CN103446066B (zh) * 2013-09-16 2014-12-24 南通丝乡丝绸有限公司 帕罗西汀冻干粉针及其制备方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL111002A (en) * 1993-09-22 1998-09-24 Glaxo Group Ltd History of piperidine, their preparation and the pharmaceutical preparations containing them
US6117855A (en) * 1996-10-07 2000-09-12 Merck Sharp & Dohme Ltd. Use of a NK-1 receptor antagonist and an antidepressant and/or an anti-anxiety agent
JP2001523245A (ja) * 1997-04-24 2001-11-20 メルク シヤープ エンド ドーム リミテツド 肥満を治療するためのnk−1受容体拮抗薬およびssriの使用
GB9923748D0 (en) * 1999-10-07 1999-12-08 Glaxo Group Ltd Chemical compounds
US6436928B1 (en) * 1999-12-17 2002-08-20 Schering Corporation Selective neurokinin antagonists
JP2003522739A (ja) * 1999-12-17 2003-07-29 シェーリング コーポレイション 選択的ニューロキニンアンタゴニスト
GT200100147A (es) * 2000-07-31 2002-06-25 Derivados de imidazol
GB0025354D0 (en) * 2000-10-17 2000-11-29 Glaxo Group Ltd Chemical compounds
GB0119797D0 (en) * 2001-08-14 2001-10-03 Glaxo Group Ltd Chemical compounds
ATE374183T1 (de) * 2001-11-13 2007-10-15 Schering Corp Nk1-antagonisten
GB0203020D0 (en) * 2002-02-08 2002-03-27 Glaxo Group Ltd Chemical compounds

Also Published As

Publication number Publication date
EP1615641A1 (en) 2006-01-18
CA2522311A1 (en) 2004-10-28
EP1653956A1 (en) 2006-05-10
RU2005135649A (ru) 2006-03-20
AU2004229181A1 (en) 2004-10-28
US20060241124A1 (en) 2006-10-26
PL377858A1 (pl) 2006-02-20
US20060287325A1 (en) 2006-12-21
JP2006523650A (ja) 2006-10-19
MA27731A1 (fr) 2006-01-02
ZA200508067B (en) 2007-02-28
JP2006523649A (ja) 2006-10-19
BRPI0409379A (pt) 2006-04-25
JP2006523652A (ja) 2006-10-19
MA27730A1 (fr) 2006-01-02
GB0308968D0 (en) 2003-05-28
RU2005135647A (ru) 2006-06-10
WO2004091615A1 (en) 2004-10-28
WO2004091617A1 (en) 2004-10-28
NO20055368L (no) 2005-11-14
ZA200508068B (en) 2007-02-28
CA2522313A1 (en) 2004-10-28
AU2004229179A1 (en) 2004-10-28
PL377857A1 (pl) 2006-02-20
CO5700753A2 (es) 2006-11-30
BRPI0409377A (pt) 2006-04-25
MXPA05011063A (es) 2005-12-12
CN1809359A (zh) 2006-07-26
IS8128A (is) 2005-11-15
MXPA05011064A (es) 2006-04-18
IS8129A (is) 2005-11-15
CN1809355A (zh) 2006-07-26
WO2004091624A1 (en) 2004-10-28
KR20060003875A (ko) 2006-01-11
JP2006523651A (ja) 2006-10-19
US20060217395A1 (en) 2006-09-28
KR20060003876A (ko) 2006-01-11
EP1613325A1 (en) 2006-01-11
US20060241143A1 (en) 2006-10-26
WO2004091616A1 (en) 2004-10-28
EP1615642A1 (en) 2006-01-18

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