NO20054291L - Trimmed macrocyclic substituted benzene derivatives - Google Patents

Trimmed macrocyclic substituted benzene derivatives

Info

Publication number
NO20054291L
NO20054291L NO20054291A NO20054291A NO20054291L NO 20054291 L NO20054291 L NO 20054291L NO 20054291 A NO20054291 A NO 20054291A NO 20054291 A NO20054291 A NO 20054291A NO 20054291 L NO20054291 L NO 20054291L
Authority
NO
Norway
Prior art keywords
trimmed
substituted benzene
benzene derivatives
macrocyclic
macrocyclic substituted
Prior art date
Application number
NO20054291A
Other languages
Norwegian (no)
Other versions
NO20054291D0 (en
Inventor
Hanns-Joachim Weinmann
Johannes Platzek
Heiko Schirmer
Jose Luis Martin
Juan R Harto
Bjorn Riefke
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of NO20054291D0 publication Critical patent/NO20054291D0/en
Publication of NO20054291L publication Critical patent/NO20054291L/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10—Organic compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/0002—General or multifunctional contrast agents, e.g. chelated agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/04—X-ray contrast preparations
    • A61K49/0433—X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/04—X-ray contrast preparations
    • A61K49/0433—X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
    • A61K49/0438—Organic X-ray contrast-enhancing agent comprising an iodinated group or an iodine atom, e.g. iopamidol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/085—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier conjugated systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0497—Organic compounds conjugates with a carrier being an organic compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Radiology & Medical Imaging (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Optics & Photonics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

Metallkompleksene med den generelle formel (I), hvori Hal står for brom eller jod og Aog A2 har forskjellige betydninger, er egnede som kontrastmidler.The metal complexes of the general formula (I), in which Hal stands for bromine or iodine and Aog A2 have different meanings, are suitable as contrast agents.

NO20054291A 2003-02-19 2005-09-16 Trimmed macrocyclic substituted benzene derivatives NO20054291L (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10307759A DE10307759B3 (en) 2003-02-19 2003-02-19 Trimers of macrocyclically substituted benzene derivatives, their production and use as contrast media and pharmaceutical compositions containing them
PCT/EP2003/014149 WO2004074267A1 (en) 2003-02-19 2003-12-12 Trimeric macrocyclically substituted benzene derivatives

Publications (2)

Publication Number Publication Date
NO20054291D0 NO20054291D0 (en) 2005-09-16
NO20054291L true NO20054291L (en) 2005-11-17

Family

ID=32891780

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20054291A NO20054291L (en) 2003-02-19 2005-09-16 Trimmed macrocyclic substituted benzene derivatives

Country Status (16)

Country Link
EP (1) EP1594851A1 (en)
JP (1) JP2006514664A (en)
KR (1) KR20050105474A (en)
CN (1) CN1753878A (en)
AR (1) AR043205A1 (en)
AU (1) AU2003290032B2 (en)
BR (1) BR0318125A (en)
CA (1) CA2516467A1 (en)
CR (1) CR7937A (en)
DE (1) DE10307759B3 (en)
EC (1) ECSP056026A (en)
MX (1) MXPA05008781A (en)
NO (1) NO20054291L (en)
RU (1) RU2005128834A (en)
WO (1) WO2004074267A1 (en)
ZA (1) ZA200507437B (en)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2165768B1 (en) 1999-07-14 2003-04-01 Almirall Prodesfarma Sa NEW DERIVATIVES OF QUINUCLIDINE AND PHARMACEUTICAL COMPOSITIONS THAT CONTAIN THEM.
DE102004023093B3 (en) * 2004-05-05 2006-03-02 Schering Ag Trimere macrocyclic substituted halogen-benzene derivatives
DE102004026103A1 (en) * 2004-05-25 2005-12-22 Schering Ag Trimere macrocyclic substituted aminoisophthalic acid-halogenated benzene derivatives
ES2257152B1 (en) * 2004-05-31 2007-07-01 Laboratorios Almirall S.A. COMBINATIONS THAT INCLUDE ANTIMUSCARINIC AGENTS AND BETA-ADRENERGIC AGONISTS.
DE102007058220A1 (en) 2007-12-03 2009-06-04 Bayer Schering Pharma Aktiengesellschaft New metal complexes useful e.g. for manufacturing agent for X-ray diagnostics and magnetic resonance tomography-diagnostics of brain infarcts and liver tumor, and/or space-process in liver and abdomen tumors and musculoskeletal tumors
EP2100599A1 (en) 2008-03-13 2009-09-16 Laboratorios Almirall, S.A. Inhalation composition containing aclidinium for treatment of asthma and chronic obstructive pulmonary disease
EP2100598A1 (en) 2008-03-13 2009-09-16 Laboratorios Almirall, S.A. Inhalation composition containing aclidinium for treatment of asthma and chronic obstructive pulmonary disease
WO2012027727A2 (en) * 2010-08-26 2012-03-01 Kunyuan Cui Lipomacrocycles and uses thereof
EP2510928A1 (en) 2011-04-15 2012-10-17 Almirall, S.A. Aclidinium for use in improving the quality of sleep in respiratory patients
CN104672259B (en) * 2015-02-02 2017-04-05 湖北大学 A kind of rare-earth europium containing iodine (III) complex and its preparation method and application
CN104721844B (en) * 2015-02-02 2017-11-03 湖北大学 A kind of new CT, MRI, the functional microsphere of rare-earth fluorescent three and its preparation method and application
EP3101012A1 (en) 2015-06-04 2016-12-07 Bayer Pharma Aktiengesellschaft New gadolinium chelate compounds for use in magnetic resonance imaging
CN105254529B (en) * 2015-09-21 2017-05-31 西南石油大学 A kind of preparation method of tree-like schiff bases corrosion inhibiter
KR102464647B1 (en) 2016-11-28 2022-11-08 바이엘 파마 악티엔게젤샤프트 High Relaxation Gadolinium Chelate Compounds for Use in Magnetic Resonance Imaging
CN107445911B (en) * 2017-06-19 2019-07-05 南京科技职业学院 Two core mr contrast agents containing gadolinium of one kind and its preparation and application
CN113164628A (en) 2018-11-23 2021-07-23 拜耳股份有限公司 Contrast medium preparation and preparation method thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5324503A (en) * 1992-02-06 1994-06-28 Mallinckrodt Medical, Inc. Iodo-phenylated chelates for x-ray contrast
AU6996594A (en) * 1993-06-02 1994-12-20 Bracco S.P.A. Iodinated paramagnetic chelates, and their use as contrast agents
FR2736051B3 (en) * 1995-06-29 1997-09-26 Guerbet Sa METAL COMPLEXES OF POLYAMINOACIDS, THEIR PREPARATION PROCESS AND THEIR USE IN DIAGNOSTIC IMAGING
FR2793795B1 (en) * 1999-05-21 2001-08-03 Guerbet Sa ISOMERS OF TETRAMIDS OF THE ACID GADOLINIUM COMPLEX (1,4,7,10-TETRAZACYCLODODECANE) 1,4,7,10-TETRA (2-GLUTARIC) THEIR PREPARATION PROCESS AND THEIR APPLICATION IN MEDICAL IMAGING
FR2794744B1 (en) * 1999-06-09 2001-09-21 Guerbet Sa METAL COMPLEXES OF BICYCLIC POLYAMINOACIDS, THEIR PREPARATION PROCESS AND THEIR APPLICATION IN MEDICAL IMAGING

Also Published As

Publication number Publication date
ZA200507437B (en) 2007-02-28
NO20054291D0 (en) 2005-09-16
EP1594851A1 (en) 2005-11-16
AU2003290032A1 (en) 2004-09-09
WO2004074267A1 (en) 2004-09-02
RU2005128834A (en) 2006-03-20
DE10307759B3 (en) 2004-11-18
CA2516467A1 (en) 2004-09-02
AR043205A1 (en) 2005-07-20
MXPA05008781A (en) 2006-03-10
CN1753878A (en) 2006-03-29
KR20050105474A (en) 2005-11-04
JP2006514664A (en) 2006-05-11
CR7937A (en) 2006-02-07
ECSP056026A (en) 2006-01-27
AU2003290032B2 (en) 2009-04-23
BR0318125A (en) 2006-02-07

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