CR7937A - BENEFIT DERIVATIVES REPLACED WITH MACROCICLIC TRIMEROS - Google Patents
BENEFIT DERIVATIVES REPLACED WITH MACROCICLIC TRIMEROSInfo
- Publication number
- CR7937A CR7937A CR7937A CR7937A CR7937A CR 7937 A CR7937 A CR 7937A CR 7937 A CR7937 A CR 7937A CR 7937 A CR7937 A CR 7937A CR 7937 A CR7937 A CR 7937A
- Authority
- CR
- Costa Rica
- Prior art keywords
- trimeros
- macrociclic
- benefit
- derivatives replaced
- derivatives
- Prior art date
Links
- 239000002184 metal Substances 0.000 abstract 2
- ZCYVEMRRCGMTRW-UHFFFAOYSA-N 7553-56-2 Chemical compound [I] ZCYVEMRRCGMTRW-UHFFFAOYSA-N 0.000 abstract 1
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical compound [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 abstract 1
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Substances BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 abstract 1
- 229910052794 bromium Inorganic materials 0.000 abstract 1
- 229940039231 contrast media Drugs 0.000 abstract 1
- 239000002872 contrast media Substances 0.000 abstract 1
- 229910052740 iodine Inorganic materials 0.000 abstract 1
- 239000011630 iodine Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
- A61K49/10—Organic compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
- C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/0002—General or multifunctional contrast agents, e.g. chelated agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/04—X-ray contrast preparations
- A61K49/0433—X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/04—X-ray contrast preparations
- A61K49/0433—X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
- A61K49/0438—Organic X-ray contrast-enhancing agent comprising an iodinated group or an iodine atom, e.g. iopamidol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
- A61K49/085—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier conjugated systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0497—Organic compounds conjugates with a carrier being an organic compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Radiology & Medical Imaging (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Optics & Photonics (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Abstract
El invento se refiere a complejos metalicos de la formula (I), donde Hal representa bromo o yodo y A1 y A2 tienen significados diferentes. Los complejos metalicos de acuerdo con el invento son adecuados para ser usados como medios de contraste.The invention relates to metal complexes of the formula (I), where Hal represents bromine or iodine and A1 and A2 have different meanings. The metal complexes according to the invention are suitable for use as contrast media.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE10307759A DE10307759B3 (en) | 2003-02-19 | 2003-02-19 | Trimers of macrocyclically substituted benzene derivatives, their production and use as contrast media and pharmaceutical compositions containing them |
Publications (1)
Publication Number | Publication Date |
---|---|
CR7937A true CR7937A (en) | 2006-02-07 |
Family
ID=32891780
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CR7937A CR7937A (en) | 2003-02-19 | 2005-08-09 | BENEFIT DERIVATIVES REPLACED WITH MACROCICLIC TRIMEROS |
Country Status (16)
Country | Link |
---|---|
EP (1) | EP1594851A1 (en) |
JP (1) | JP2006514664A (en) |
KR (1) | KR20050105474A (en) |
CN (1) | CN1753878A (en) |
AR (1) | AR043205A1 (en) |
AU (1) | AU2003290032B2 (en) |
BR (1) | BR0318125A (en) |
CA (1) | CA2516467A1 (en) |
CR (1) | CR7937A (en) |
DE (1) | DE10307759B3 (en) |
EC (1) | ECSP056026A (en) |
MX (1) | MXPA05008781A (en) |
NO (1) | NO20054291L (en) |
RU (1) | RU2005128834A (en) |
WO (1) | WO2004074267A1 (en) |
ZA (1) | ZA200507437B (en) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2165768B1 (en) | 1999-07-14 | 2003-04-01 | Almirall Prodesfarma Sa | NEW DERIVATIVES OF QUINUCLIDINE AND PHARMACEUTICAL COMPOSITIONS THAT CONTAIN THEM. |
DE102004023093B3 (en) * | 2004-05-05 | 2006-03-02 | Schering Ag | Trimere macrocyclic substituted halogen-benzene derivatives |
DE102004026103A1 (en) * | 2004-05-25 | 2005-12-22 | Schering Ag | Trimere macrocyclic substituted aminoisophthalic acid-halogenated benzene derivatives |
ES2257152B1 (en) * | 2004-05-31 | 2007-07-01 | Laboratorios Almirall S.A. | COMBINATIONS THAT INCLUDE ANTIMUSCARINIC AGENTS AND BETA-ADRENERGIC AGONISTS. |
DE102007058220A1 (en) | 2007-12-03 | 2009-06-04 | Bayer Schering Pharma Aktiengesellschaft | New metal complexes useful e.g. for manufacturing agent for X-ray diagnostics and magnetic resonance tomography-diagnostics of brain infarcts and liver tumor, and/or space-process in liver and abdomen tumors and musculoskeletal tumors |
EP2100599A1 (en) | 2008-03-13 | 2009-09-16 | Laboratorios Almirall, S.A. | Inhalation composition containing aclidinium for treatment of asthma and chronic obstructive pulmonary disease |
EP2100598A1 (en) | 2008-03-13 | 2009-09-16 | Laboratorios Almirall, S.A. | Inhalation composition containing aclidinium for treatment of asthma and chronic obstructive pulmonary disease |
WO2012027727A2 (en) * | 2010-08-26 | 2012-03-01 | Kunyuan Cui | Lipomacrocycles and uses thereof |
EP2510928A1 (en) | 2011-04-15 | 2012-10-17 | Almirall, S.A. | Aclidinium for use in improving the quality of sleep in respiratory patients |
CN104672259B (en) * | 2015-02-02 | 2017-04-05 | 湖北大学 | A kind of rare-earth europium containing iodine (III) complex and its preparation method and application |
CN104721844B (en) * | 2015-02-02 | 2017-11-03 | 湖北大学 | A kind of new CT, MRI, the functional microsphere of rare-earth fluorescent three and its preparation method and application |
EP3101012A1 (en) | 2015-06-04 | 2016-12-07 | Bayer Pharma Aktiengesellschaft | New gadolinium chelate compounds for use in magnetic resonance imaging |
CN105254529B (en) * | 2015-09-21 | 2017-05-31 | 西南石油大学 | A kind of preparation method of tree-like schiff bases corrosion inhibiter |
KR102464647B1 (en) | 2016-11-28 | 2022-11-08 | 바이엘 파마 악티엔게젤샤프트 | High Relaxation Gadolinium Chelate Compounds for Use in Magnetic Resonance Imaging |
CN107445911B (en) * | 2017-06-19 | 2019-07-05 | 南京科技职业学院 | Two core mr contrast agents containing gadolinium of one kind and its preparation and application |
CN113164628A (en) | 2018-11-23 | 2021-07-23 | 拜耳股份有限公司 | Contrast medium preparation and preparation method thereof |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5324503A (en) * | 1992-02-06 | 1994-06-28 | Mallinckrodt Medical, Inc. | Iodo-phenylated chelates for x-ray contrast |
AU6996594A (en) * | 1993-06-02 | 1994-12-20 | Bracco S.P.A. | Iodinated paramagnetic chelates, and their use as contrast agents |
FR2736051B3 (en) * | 1995-06-29 | 1997-09-26 | Guerbet Sa | METAL COMPLEXES OF POLYAMINOACIDS, THEIR PREPARATION PROCESS AND THEIR USE IN DIAGNOSTIC IMAGING |
FR2793795B1 (en) * | 1999-05-21 | 2001-08-03 | Guerbet Sa | ISOMERS OF TETRAMIDS OF THE ACID GADOLINIUM COMPLEX (1,4,7,10-TETRAZACYCLODODECANE) 1,4,7,10-TETRA (2-GLUTARIC) THEIR PREPARATION PROCESS AND THEIR APPLICATION IN MEDICAL IMAGING |
FR2794744B1 (en) * | 1999-06-09 | 2001-09-21 | Guerbet Sa | METAL COMPLEXES OF BICYCLIC POLYAMINOACIDS, THEIR PREPARATION PROCESS AND THEIR APPLICATION IN MEDICAL IMAGING |
-
2003
- 2003-02-19 DE DE10307759A patent/DE10307759B3/en not_active Expired - Fee Related
- 2003-12-12 MX MXPA05008781A patent/MXPA05008781A/en active IP Right Grant
- 2003-12-12 KR KR1020057015199A patent/KR20050105474A/en not_active Application Discontinuation
- 2003-12-12 CN CNA2003801098702A patent/CN1753878A/en active Pending
- 2003-12-12 CA CA002516467A patent/CA2516467A1/en not_active Abandoned
- 2003-12-12 BR BR0318125-1A patent/BR0318125A/en not_active IP Right Cessation
- 2003-12-12 EP EP03782386A patent/EP1594851A1/en not_active Withdrawn
- 2003-12-12 JP JP2004568408A patent/JP2006514664A/en not_active Withdrawn
- 2003-12-12 WO PCT/EP2003/014149 patent/WO2004074267A1/en active Application Filing
- 2003-12-12 AU AU2003290032A patent/AU2003290032B2/en not_active Expired - Fee Related
- 2003-12-12 RU RU2005128834/04A patent/RU2005128834A/en not_active Application Discontinuation
-
2004
- 2004-02-18 AR ARP040100490A patent/AR043205A1/en unknown
-
2005
- 2005-08-09 CR CR7937A patent/CR7937A/en not_active Application Discontinuation
- 2005-09-15 ZA ZA200507437A patent/ZA200507437B/en unknown
- 2005-09-16 NO NO20054291A patent/NO20054291L/en not_active Application Discontinuation
- 2005-09-19 EC EC2005006026A patent/ECSP056026A/en unknown
Also Published As
Publication number | Publication date |
---|---|
ZA200507437B (en) | 2007-02-28 |
NO20054291D0 (en) | 2005-09-16 |
EP1594851A1 (en) | 2005-11-16 |
NO20054291L (en) | 2005-11-17 |
AU2003290032A1 (en) | 2004-09-09 |
WO2004074267A1 (en) | 2004-09-02 |
RU2005128834A (en) | 2006-03-20 |
DE10307759B3 (en) | 2004-11-18 |
CA2516467A1 (en) | 2004-09-02 |
AR043205A1 (en) | 2005-07-20 |
MXPA05008781A (en) | 2006-03-10 |
CN1753878A (en) | 2006-03-29 |
KR20050105474A (en) | 2005-11-04 |
JP2006514664A (en) | 2006-05-11 |
ECSP056026A (en) | 2006-01-27 |
AU2003290032B2 (en) | 2009-04-23 |
BR0318125A (en) | 2006-02-07 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FA | Abandonment or withdrawal (granting procedure) |