NO20052954L - Diterpenoidforbindelser, sammensetninger derav og deres anvendelse som anti-cancer eller anti-fungale midler - Google Patents

Diterpenoidforbindelser, sammensetninger derav og deres anvendelse som anti-cancer eller anti-fungale midler

Info

Publication number
NO20052954L
NO20052954L NO20052954A NO20052954A NO20052954L NO 20052954 L NO20052954 L NO 20052954L NO 20052954 A NO20052954 A NO 20052954A NO 20052954 A NO20052954 A NO 20052954A NO 20052954 L NO20052954 L NO 20052954L
Authority
NO
Norway
Prior art keywords
cancer
compositions
compounds
methods
useful
Prior art date
Application number
NO20052954A
Other languages
English (en)
Other versions
NO20052954D0 (no
Inventor
Giorgio Attardo
Pierre Beauparlant
Angela M Stafford
Rosa Ubillas
James B Mcalpine
Samuel Fortin
Sasmita Triphathy
Original Assignee
Galileo Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Galileo Pharmaceuticals Inc filed Critical Galileo Pharmaceuticals Inc
Publication of NO20052954D0 publication Critical patent/NO20052954D0/no
Publication of NO20052954L publication Critical patent/NO20052954L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/74—Esters of carboxylic acids having an esterified carboxyl group bound to a carbon atom of a ring other than a six-membered aromatic ring
    • C07C69/757—Esters of carboxylic acids having an esterified carboxyl group bound to a carbon atom of a ring other than a six-membered aromatic ring having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/04—Saturated compounds containing keto groups bound to acyclic carbon atoms
    • C07C49/12—Ketones containing more than one keto group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A61K31/121—Ketones acyclic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/10—Drugs for disorders of the urinary system of the bladder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/03—Ethers having all ether-oxygen atoms bound to acyclic carbon atoms
    • C07C43/14—Unsaturated ethers
    • C07C43/162—Unsaturated ethers containing rings other than six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/27—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation
    • C07C45/29—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation of hydroxy groups
    • C07C45/292—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation of hydroxy groups with chromium derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/20—Unsaturated compounds containing keto groups bound to acyclic carbon atoms
    • C07C49/225—Unsaturated compounds containing keto groups bound to acyclic carbon atoms containing six-membered aromatic rings and other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/753—Unsaturated compounds containing a keto groups being part of a ring containing ether groups, groups, groups, or groups
    • C07C49/755—Unsaturated compounds containing a keto groups being part of a ring containing ether groups, groups, groups, or groups a keto group being part of a condensed ring system with two or three rings, at least one ring being a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00—Systems containing at least three condensed rings
    • C07C2603/02—Ortho- or ortho- and peri-condensed systems
    • C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
    • C07C2603/22—Ortho- or ortho- and peri-condensed systems containing three rings containing only six-membered rings
    • C07C2603/26—Phenanthrenes; Hydrogenated phenanthrenes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Communicable Diseases (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Det beskrives diterpenoidforbindelser, preparater inneholdende en effektiv mengde av en diterpenoid forbindelse samt metoder som er brukbare for terapi eller prevensjon av cancer eller en neoplastisk lidelse omfattende administrering av en effektiv mengde av en diterpenoid forbindelse. Forbindelsene, preparatene og metodene er også brukbare for å inhibere veksten av en cancercelle eller en neoplastisk celle, eller for indusering av apoptose i en cancer- eller neoplastisk celle. Forbindelsene, preparatene og metodene ifølge oppfinnelsen er videre brukbare for terapi eller prevensjon av en fungal infeksjon. Forbindelsene, preparatene og metodene ifølge oppfinnelsen er også brukbare for inhibering av veksten av en fungus.
NO20052954A 2002-12-05 2005-06-16 Diterpenoidforbindelser, sammensetninger derav og deres anvendelse som anti-cancer eller anti-fungale midler NO20052954L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US43109602P 2002-12-05 2002-12-05
PCT/US2003/038659 WO2004052282A2 (en) 2002-12-05 2003-12-04 Diterpenoid compounds, compositions thereof and their use as anti-cancer or anti-fungal agents

Publications (2)

Publication Number Publication Date
NO20052954D0 NO20052954D0 (no) 2005-06-16
NO20052954L true NO20052954L (no) 2005-09-01

Family

ID=32507669

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20052954A NO20052954L (no) 2002-12-05 2005-06-16 Diterpenoidforbindelser, sammensetninger derav og deres anvendelse som anti-cancer eller anti-fungale midler

Country Status (12)

Country Link
US (1) US7217844B2 (no)
EP (1) EP1578711A4 (no)
JP (1) JP2006515292A (no)
KR (1) KR20050105975A (no)
CN (1) CN1745054A (no)
AU (1) AU2003297671A1 (no)
BR (1) BR0317052A (no)
CA (1) CA2508002A1 (no)
NO (1) NO20052954L (no)
PL (1) PL377303A1 (no)
WO (1) WO2004052282A2 (no)
ZA (1) ZA200504466B (no)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20080131968A1 (en) * 2002-08-28 2008-06-05 Nomir Medical Technologies, Inc. Near-infrared electromagnetic modification of cellular steady-state membrane potentials
US7795311B2 (en) * 2007-10-15 2010-09-14 Pittsburg State University Methods and compositions for the management of soil-borne fungal diseases
US8546572B2 (en) * 2008-03-31 2013-10-01 Sun Pharmaceutical Industries Limited Process for the preparation of morphinane analogues
CN101880269B (zh) * 2010-06-30 2012-05-23 浙江工商大学 二萜单体及从大青中分离制备二萜单体的方法
CN108929857B (zh) * 2017-05-26 2021-10-29 中国海洋大学 一种柳珊瑚来源的海洋真菌及其在制备拓扑异构酶i抑制剂中的应用

Also Published As

Publication number Publication date
NO20052954D0 (no) 2005-06-16
PL377303A1 (pl) 2006-01-23
EP1578711A2 (en) 2005-09-28
US7217844B2 (en) 2007-05-15
WO2004052282A2 (en) 2004-06-24
ZA200504466B (en) 2006-10-25
KR20050105975A (ko) 2005-11-08
US20050070540A1 (en) 2005-03-31
CA2508002A1 (en) 2004-06-24
WO2004052282A3 (en) 2004-10-07
EP1578711A4 (en) 2006-09-27
CN1745054A (zh) 2006-03-08
AU2003297671A1 (en) 2004-06-30
JP2006515292A (ja) 2006-05-25
BR0317052A (pt) 2005-10-25

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