NO20052916L - Fremgangsmate for rensingen av TNF-bindende proteiner ved anvendelse av IMAC - Google Patents

Fremgangsmate for rensingen av TNF-bindende proteiner ved anvendelse av IMAC

Info

Publication number
NO20052916L
NO20052916L NO20052916A NO20052916A NO20052916L NO 20052916 L NO20052916 L NO 20052916L NO 20052916 A NO20052916 A NO 20052916A NO 20052916 A NO20052916 A NO 20052916A NO 20052916 L NO20052916 L NO 20052916L
Authority
NO
Norway
Prior art keywords
binding proteins
imac
purification
tnf binding
metal
Prior art date
Application number
NO20052916A
Other languages
English (en)
Other versions
NO20052916D0 (no
Inventor
Mara Rossi
Original Assignee
Ares Trading Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ares Trading Sa filed Critical Ares Trading Sa
Publication of NO20052916L publication Critical patent/NO20052916L/no
Publication of NO20052916D0 publication Critical patent/NO20052916D0/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7151—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for tumor necrosis factor [TNF], for lymphotoxin [LT]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/22—Affinity chromatography or related techniques based upon selective absorption processes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/38—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 and B01D15/30 - B01D15/36, e.g. affinity, ligand exchange or chiral chromatography
    • B01D15/3804—Affinity chromatography
    • B01D15/3828—Ligand exchange chromatography, e.g. complexation, chelation or metal interaction chromatography

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

En ny renseprosess for tumomekrosefaktorbindende proteiner beskrives. Derme fremgangsmåten er kjermetegnet ved anvendelsen av et fangetrirm i immobUisert metallaffinitetskromatografi (IMAe) ved anvendelse av kobber som metall. Dette medfører fordeler i form av utbytte, renhet til det endelige produktet og anvendelighet i industriskala.
NO20052916A 2002-11-15 2005-06-15 Fremgangsmate for rensingen av TNF-bindende proteiner ved anvendelse av IMAC NO20052916D0 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP02025755 2002-11-15
PCT/EP2003/050824 WO2004046184A1 (en) 2002-11-15 2003-11-13 Process for the purification of tnf-binding proteins using imac

Publications (2)

Publication Number Publication Date
NO20052916L true NO20052916L (no) 2005-06-15
NO20052916D0 NO20052916D0 (no) 2005-06-15

Family

ID=32319541

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20052916A NO20052916D0 (no) 2002-11-15 2005-06-15 Fremgangsmate for rensingen av TNF-bindende proteiner ved anvendelse av IMAC

Country Status (18)

Country Link
US (1) US20060128616A1 (no)
EP (1) EP1560851A1 (no)
JP (1) JP2006517187A (no)
KR (1) KR20050074997A (no)
CN (1) CN100375753C (no)
AR (1) AR042038A1 (no)
AU (1) AU2003298287A1 (no)
BG (1) BG109152A (no)
BR (1) BR0315807A (no)
CA (1) CA2505385A1 (no)
EA (1) EA200500762A1 (no)
HR (1) HRP20050406A2 (no)
MX (1) MXPA05005246A (no)
NO (1) NO20052916D0 (no)
PL (1) PL376745A1 (no)
RS (1) RS20050355A (no)
WO (1) WO2004046184A1 (no)
ZA (1) ZA200503702B (no)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102234332B (zh) * 2010-04-26 2014-12-17 浙江海正药业股份有限公司 一种重组人血白蛋白及其融合蛋白的分离纯化工艺
WO2017049529A1 (en) 2015-09-24 2017-03-30 Innolife Co., Ltd. A pharmaceutical composition comprising a copper chelating tetramine and the use thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5283339A (en) * 1988-11-23 1994-02-01 California Institute Of Technology Immobilized metal aqueous two-phase extraction and precipitation
US5169936A (en) * 1989-04-14 1992-12-08 Biogen, Inc. Protein purification on immobilized metal affinity resins effected by elution using a weak ligand
DK0393438T3 (da) * 1989-04-21 2005-05-30 Amgen Inc TNF-receptor, TNF-bindende proteiner og DNAér, der koder herfor
ATE213639T1 (de) * 1993-07-09 2002-03-15 Avant Immunotherapeutics Inc Proteinreinigung
US5932102A (en) * 1998-01-12 1999-08-03 Schering Corporation Immobilized metal, affinity chromatography

Also Published As

Publication number Publication date
CN1738835A (zh) 2006-02-22
HK1082751A1 (en) 2006-06-16
EA200500762A1 (ru) 2005-12-29
RS20050355A (sr) 2007-06-04
NO20052916D0 (no) 2005-06-15
ZA200503702B (en) 2006-08-30
BR0315807A (pt) 2005-09-20
EP1560851A1 (en) 2005-08-10
AR042038A1 (es) 2005-06-08
HRP20050406A2 (en) 2006-02-28
US20060128616A1 (en) 2006-06-15
WO2004046184A1 (en) 2004-06-03
KR20050074997A (ko) 2005-07-19
JP2006517187A (ja) 2006-07-20
CN100375753C (zh) 2008-03-19
PL376745A1 (pl) 2006-01-09
CA2505385A1 (en) 2004-06-03
AU2003298287A1 (en) 2004-06-15
MXPA05005246A (es) 2005-07-25
BG109152A (bg) 2006-04-28

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Legal Events

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