NO20052330L - Nye substituerte [1,4]benzodioksino[2,3]isoindolforbindelser, fremgangsmate for deres fremstilling og farmasoytiske sammensetninger inneholdende dem - Google Patents

Nye substituerte [1,4]benzodioksino[2,3]isoindolforbindelser, fremgangsmate for deres fremstilling og farmasoytiske sammensetninger inneholdende dem

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Publication number
NO20052330L
NO20052330L NO20052330A NO20052330A NO20052330L NO 20052330 L NO20052330 L NO 20052330L NO 20052330 A NO20052330 A NO 20052330A NO 20052330 A NO20052330 A NO 20052330A NO 20052330 L NO20052330 L NO 20052330L
Authority
NO
Norway
Prior art keywords
alkyl
branched
linear
benzodioxino
processes
Prior art date
Application number
NO20052330A
Other languages
English (en)
Other versions
NO20052330D0 (no
Inventor
Alain Pierre
Pierre Renard
John Hickman
Sylvain Routier
Stephane Leonce
Gerard Coudert
Daniel-Henri Caignard
Nathalie Ayerbe
Franck Lepifre
Original Assignee
Servier Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Servier Lab filed Critical Servier Lab
Publication of NO20052330L publication Critical patent/NO20052330L/no
Publication of NO20052330D0 publication Critical patent/NO20052330D0/no

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/12Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
    • C07D491/14Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D498/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/12Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D498/14Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D498/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/22Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains four or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Oppfinnelsen vedrører forbindelser med formel (I), hvori: * A er som definert i beskrivelsen, * Y representerer en gruppe valgt fra et oksygenatom og en metylengruppe, * R2 representerer et hydrogenatom og i dette tilfelle: representerer R3 en gruppe valgt fra et hydrogenatom og gruppene lineær eller forgrenet (Cl-C6)alkyl, aryl, aryl(Cl-C6)alkyl (hvor alkylenheten er lineær eller forgrenet) og SO2CF3, * eller R2 og R3 danner en binding, * R1 representerer en gruppe valgt fra et hydrogenatom og gruppene lineær eller forgrenet (C1-C6)alkyl, aryl og aryl(Cl-C6)alkyl (hvor alkylenheten er lineær eller forgrenet) eller en lineær eller forgrenet (Cl-C6)alkylenkjede, * Z1 og Z2, representerer hver et hydrogenatom eller Z1 og Z2 danner, sammen med karbonatomene som bærer dem, en fenylgruppe. Oppfinnelsen er nyttig for fremstilling av medikamenter.
NO20052330A 2002-10-18 2005-05-12 Nye substituerte [1,4]benzodioksino[2,3]isoindolforbindelser, fremgangsmate for deres fremstilling og farmasoytiske sammensetninger inneholdende dem NO20052330D0 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0212965A FR2845997B1 (fr) 2002-10-18 2002-10-18 Nouveaux derives de[1,4]benzodioxino[2,3-e]isoindole substitues, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
PCT/FR2003/003069 WO2004037831A1 (fr) 2002-10-18 2003-10-17 NOUVEAUX DERIVES DE [1,4]BENZODIOXINO[2,3-e]ISOINDOLE SUBSTITUES, LEUR PROCEDE DE PREPARATION ET LES COMPOSITIONS PHARMACEUTIQUES QUI LES CONTIENNENT

Publications (2)

Publication Number Publication Date
NO20052330L true NO20052330L (no) 2005-05-12
NO20052330D0 NO20052330D0 (no) 2005-05-12

Family

ID=32050502

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20052330A NO20052330D0 (no) 2002-10-18 2005-05-12 Nye substituerte [1,4]benzodioksino[2,3]isoindolforbindelser, fremgangsmate for deres fremstilling og farmasoytiske sammensetninger inneholdende dem

Country Status (28)

Country Link
US (1) US7202255B2 (no)
EP (1) EP1587810B1 (no)
JP (1) JP2006507280A (no)
KR (1) KR100695600B1 (no)
CN (1) CN100412076C (no)
AR (1) AR041654A1 (no)
AT (1) ATE344800T1 (no)
AU (1) AU2003301532A1 (no)
BR (1) BR0314878A (no)
CA (1) CA2502488A1 (no)
CY (1) CY1105972T1 (no)
DE (1) DE60309605T2 (no)
DK (1) DK1587810T3 (no)
EA (1) EA008498B1 (no)
ES (1) ES2276160T3 (no)
FR (1) FR2845997B1 (no)
GE (1) GEP20074102B (no)
MA (1) MA27340A1 (no)
MX (1) MXPA05004113A (no)
MY (1) MY136142A (no)
NO (1) NO20052330D0 (no)
NZ (1) NZ539195A (no)
PL (1) PL375956A1 (no)
PT (1) PT1587810E (no)
SI (1) SI1587810T1 (no)
UA (1) UA79997C2 (no)
WO (1) WO2004037831A1 (no)
ZA (1) ZA200502829B (no)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW201100423A (en) * 2009-03-31 2011-01-01 Arqule Inc Substituted pyrazolo-pyrrolo-pyridine-dione compounds
CN103086947A (zh) * 2011-11-04 2013-05-08 赵庆春 具有抗血管生成活性的邻苯二甲酰亚胺类化合物及其用途
KR101614599B1 (ko) * 2014-04-09 2016-04-21 주식회사 두산 유기 화합물 및 이를 포함하는 유기 전계 발광 소자

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5705511A (en) * 1994-10-14 1998-01-06 Cephalon, Inc. Fused pyrrolocarbazoles
AU4136197A (en) * 1996-09-09 1998-03-26 Kyowa Hakko Kogyo Co. Ltd. Pyrrolocarbazole derivatives
FR2755691B1 (fr) * 1996-11-08 1998-12-04 Adir Nouveaux derives 7,12-dioxa-benzo[a]anthraceniques substitues, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Also Published As

Publication number Publication date
EA200500573A1 (ru) 2005-12-29
US7202255B2 (en) 2007-04-10
GEP20074102B (en) 2007-05-10
CY1105972T1 (el) 2011-04-06
DE60309605D1 (de) 2006-12-21
FR2845997B1 (fr) 2004-12-24
EA008498B1 (ru) 2007-06-29
CA2502488A1 (fr) 2004-05-06
DE60309605T2 (de) 2007-09-27
SI1587810T1 (sl) 2007-02-28
EP1587810B1 (fr) 2006-11-08
ZA200502829B (en) 2006-08-30
JP2006507280A (ja) 2006-03-02
EP1587810A1 (fr) 2005-10-26
CN1705672A (zh) 2005-12-07
NZ539195A (en) 2007-05-31
AU2003301532A1 (en) 2004-05-13
MY136142A (en) 2008-08-29
PT1587810E (pt) 2007-02-28
MXPA05004113A (es) 2005-06-22
KR100695600B1 (ko) 2007-03-14
US20060040930A1 (en) 2006-02-23
ES2276160T3 (es) 2007-06-16
ATE344800T1 (de) 2006-11-15
BR0314878A (pt) 2005-08-02
UA79997C2 (en) 2007-08-10
PL375956A1 (en) 2005-12-12
AR041654A1 (es) 2005-05-26
FR2845997A1 (fr) 2004-04-23
DK1587810T3 (da) 2007-03-05
CN100412076C (zh) 2008-08-20
MA27340A1 (fr) 2005-05-02
KR20050056251A (ko) 2005-06-14
WO2004037831A1 (fr) 2004-05-06
NO20052330D0 (no) 2005-05-12

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