NO20050338L - Nukleotidsekvenser som koder for torsingener torsinproteiner og fremgangsmater for anvendelse av det samme for behandling av proteinaggregering - Google Patents

Nukleotidsekvenser som koder for torsingener torsinproteiner og fremgangsmater for anvendelse av det samme for behandling av proteinaggregering

Info

Publication number
NO20050338L
NO20050338L NO20050338A NO20050338A NO20050338L NO 20050338 L NO20050338 L NO 20050338L NO 20050338 A NO20050338 A NO 20050338A NO 20050338 A NO20050338 A NO 20050338A NO 20050338 L NO20050338 L NO 20050338L
Authority
NO
Norway
Prior art keywords
methods
tor
torsin
protein aggregation
genes
Prior art date
Application number
NO20050338A
Other languages
English (en)
Norwegian (no)
Inventor
Guy A Caldwell
Kim A Caldwell
Original Assignee
Univ Alabama
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Alabama filed Critical Univ Alabama
Publication of NO20050338L publication Critical patent/NO20050338L/no

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • A61P21/04Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/158Expression markers
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00Screening for compounds of potential therapeutic value
    • G01N2500/04Screening involving studying the effect of compounds C directly on molecule A (e.g. C are potential ligands for a receptor A, or potential substrates for an enzyme A)

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Neurology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Psychology (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • General Engineering & Computer Science (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Peptides Or Proteins (AREA)
NO20050338A 2002-06-24 2005-01-21 Nukleotidsekvenser som koder for torsingener torsinproteiner og fremgangsmater for anvendelse av det samme for behandling av proteinaggregering NO20050338L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/177,104 US20030235823A1 (en) 2002-06-24 2002-06-24 Nucleotide sequences that code for torsin genes, torsin proteins, and methods of using the same to treat protein-aggregation
PCT/US2003/016229 WO2004000996A2 (en) 2002-06-24 2003-06-24 Nucleotide sequences that code for torsin genes, torsin proteins, and methods of using the same to treat protein-aggregation

Publications (1)

Publication Number Publication Date
NO20050338L true NO20050338L (no) 2005-02-21

Family

ID=29734294

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20050338A NO20050338L (no) 2002-06-24 2005-01-21 Nukleotidsekvenser som koder for torsingener torsinproteiner og fremgangsmater for anvendelse av det samme for behandling av proteinaggregering

Country Status (7)

Country Link
US (3) US20030235823A1 (ja)
EP (1) EP1572951A2 (ja)
JP (1) JP2006517383A (ja)
AU (1) AU2003243299A1 (ja)
CA (1) CA2490746A1 (ja)
NO (1) NO20050338L (ja)
WO (1) WO2004000996A2 (ja)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7838287B2 (en) * 2001-01-25 2010-11-23 Evolva Sa Library of a collection of cells
US8008459B2 (en) * 2001-01-25 2011-08-30 Evolva Sa Concatemers of differentially expressed multiple genes
CA2511229A1 (en) * 2002-01-25 2003-07-31 Evolva Ltd. Methods for multiple parameter screening and evolution of cells to produce small molecules with multiple functionalities
ATE527366T1 (de) * 2002-08-01 2011-10-15 Evolva Ltd Verfahren zur mischung von vielen heterologen genen
NZ538145A (en) * 2002-08-07 2008-05-30 Univ Delaware Compositions and methods for the treatment of diseases exhibiting protein misassembly and aggregation
AU2004213797B2 (en) * 2003-02-14 2009-09-17 Biogen Ma Inc. An expression cassette and vector for transient or stable expression of exogenous molecules
DE602004013319T2 (de) * 2003-07-11 2009-07-09 Remynd Nv Hefemodell für die toxizität amyloidogener proteine
JP2008531019A (ja) * 2005-02-25 2008-08-14 ザ・ボード・オブ・トラスティーズ・オブ・ザ・ユニバーシティー・オブ・アラバマ・フォー・アンド・オン・ビハーフ・オブ・ザ・ユニバーシティー・オブ・アラバマ タンパク質のミスフォールディングおよび凝集の制御因子ならびにその制御因子の使用の方法
US20070212333A1 (en) * 2005-10-11 2007-09-13 University Of Illinois Urbana Methods and compositions for the treatment of dystonia
US20100129796A1 (en) * 2008-11-24 2010-05-27 Micah Halpern Dye probe fluorescence resonance energy transfer genotyping

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6921814B2 (en) * 1997-06-19 2005-07-26 The General Hospital Corporation Torsin, torsin-related genes and methods of detecting neuronal disease
CA2294472C (en) * 1997-06-19 2010-06-15 The General Hospital Corporation Torsin, torsin genes, and methods of use

Also Published As

Publication number Publication date
EP1572951A2 (en) 2005-09-14
US20030235823A1 (en) 2003-12-25
WO2004000996A2 (en) 2003-12-31
US20050227279A1 (en) 2005-10-13
JP2006517383A (ja) 2006-07-27
CA2490746A1 (en) 2003-12-31
US20060068472A1 (en) 2006-03-30
AU2003243299A1 (en) 2004-01-06

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