NO20034029L - Substituerte dimetyl-[1-(1-fenyl-cykloheksyl)-piperidin-3-yl metyl]-aminerog anvendelse derav som analgetika - Google Patents

Substituerte dimetyl-[1-(1-fenyl-cykloheksyl)-piperidin-3-yl metyl]-aminerog anvendelse derav som analgetika

Info

Publication number
NO20034029L
NO20034029L NO20034029A NO20034029A NO20034029L NO 20034029 L NO20034029 L NO 20034029L NO 20034029 A NO20034029 A NO 20034029A NO 20034029 A NO20034029 A NO 20034029A NO 20034029 L NO20034029 L NO 20034029L
Authority
NO
Norway
Prior art keywords
piperidin
ylmethyl
phenylcyclohexyl
analgesics
amine
Prior art date
Application number
NO20034029A
Other languages
English (en)
Norwegian (no)
Other versions
NO20034029D0 (no
Inventor
Michael Sattlegger
Elke Reissmueller
Original Assignee
Gruenenthal Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gruenenthal Gmbh filed Critical Gruenenthal Gmbh
Publication of NO20034029D0 publication Critical patent/NO20034029D0/no
Publication of NO20034029L publication Critical patent/NO20034029L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40Oxygen atoms
    • C07D211/44Oxygen atoms attached in position 4
    • C07D211/48Oxygen atoms attached in position 4 having an acyclic carbon atom attached in position 4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40Oxygen atoms
    • C07D211/44Oxygen atoms attached in position 4
    • C07D211/46Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A61P29/02Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/26Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/70Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Plural Heterocyclic Compounds (AREA)
NO20034029A 2001-03-14 2003-09-11 Substituerte dimetyl-[1-(1-fenyl-cykloheksyl)-piperidin-3-yl metyl]-aminerog anvendelse derav som analgetika NO20034029L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10112198A DE10112198A1 (de) 2001-03-14 2001-03-14 Substituierte Dimethyl-[1-(1-phenyl-cyclohexyl)-piperidin-3-ylmethyl]-amine
PCT/EP2002/002723 WO2002072550A1 (de) 2001-03-14 2002-03-13 Substituierte dimethyl`1-(1-phenyl-cyclohexyl)-piperidin-3-ylmethyl!-amine und verwendung als analgetika

Publications (2)

Publication Number Publication Date
NO20034029D0 NO20034029D0 (no) 2003-09-11
NO20034029L true NO20034029L (no) 2003-11-13

Family

ID=7677392

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20034029A NO20034029L (no) 2001-03-14 2003-09-11 Substituerte dimetyl-[1-(1-fenyl-cykloheksyl)-piperidin-3-yl metyl]-aminerog anvendelse derav som analgetika

Country Status (23)

Country Link
US (1) US7049327B2 (es)
EP (1) EP1370529B1 (es)
JP (1) JP2004526726A (es)
KR (1) KR20040012733A (es)
CN (1) CN1496352A (es)
AT (1) ATE315551T1 (es)
BR (1) BR0208243A (es)
CA (1) CA2440758A1 (es)
CZ (1) CZ20032455A3 (es)
DE (2) DE10112198A1 (es)
DK (1) DK1370529T3 (es)
EC (1) ECSP034768A (es)
ES (1) ES2256499T3 (es)
HU (1) HUP0302800A2 (es)
IL (1) IL157893A0 (es)
MX (1) MXPA03007967A (es)
NO (1) NO20034029L (es)
PE (1) PE20020926A1 (es)
PL (1) PL364415A1 (es)
RU (1) RU2003129061A (es)
SK (1) SK11122003A3 (es)
WO (1) WO2002072550A1 (es)
ZA (1) ZA200307964B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105646332B (zh) * 2014-11-09 2018-05-25 复旦大学 氨基甲基哌啶类衍生物及其制备方法和药物用途
WO2018136546A1 (en) * 2017-01-17 2018-07-26 Mebias Discovery Llc Substituted 3-dialkylaminomethyl-piperidin-4-yl-benzamides and methods of making and using same

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL40064A0 (en) * 1972-08-07 1972-10-29 Univ Tel Aviv Phencyclidine and its derivatives as short-time acting midriatics
US4598153A (en) * 1984-12-19 1986-07-01 The United States Of America As Represented By The Department Of Health And Human Services Metaphit, a specific acylating agent for the [3 H] phencyclidine
US5155212A (en) * 1986-05-21 1992-10-13 Abbott Laboratories Phencyclidine and phencyclidine metabolites assay, tracers, immunogens, antibodies and reagent kit
ATE212981T1 (de) * 1994-09-30 2002-02-15 Novartis Erfind Verwalt Gmbh 1-acyl-4-aliphatische aminopiperidin verbindungen
EP0986555A1 (fr) * 1997-06-03 2000-03-22 Societe De Conseils De Recherches Et D'applications Scientifiques (S.C.R.A.S.) Nouveaux derives de phencyclidines, des procedes pour leur preparation et des compositions pharmaceutiques les contenant
ID29137A (id) * 1998-07-27 2001-08-02 Schering Corp Ligan-ligan afinitas tinggi untuk reseptor nosiseptin orl-1
DE10000312A1 (de) * 2000-01-05 2001-07-12 Gruenenthal Gmbh Substituierte Aminomethyl-Phenyl-Cyclohexanderivate

Also Published As

Publication number Publication date
DE50205593D1 (de) 2006-04-06
ATE315551T1 (de) 2006-02-15
SK11122003A3 (sk) 2004-01-08
US20040127516A1 (en) 2004-07-01
JP2004526726A (ja) 2004-09-02
PL364415A1 (en) 2004-12-13
ES2256499T3 (es) 2006-07-16
IL157893A0 (en) 2004-03-28
NO20034029D0 (no) 2003-09-11
ZA200307964B (en) 2004-09-14
CA2440758A1 (en) 2002-09-19
DK1370529T3 (da) 2006-05-22
KR20040012733A (ko) 2004-02-11
PE20020926A1 (es) 2002-10-26
US7049327B2 (en) 2006-05-23
HUP0302800A2 (hu) 2003-11-28
WO2002072550A1 (de) 2002-09-19
DE10112198A1 (de) 2002-09-19
EP1370529A1 (de) 2003-12-17
RU2003129061A (ru) 2005-04-10
ECSP034768A (es) 2003-10-28
CZ20032455A3 (cs) 2003-12-17
MXPA03007967A (es) 2004-10-15
CN1496352A (zh) 2004-05-12
EP1370529B1 (de) 2006-01-11
BR0208243A (pt) 2004-03-09

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