NO20022923D0 - Inhibitorer av farnesyl-protein-transferase - Google Patents
Inhibitorer av farnesyl-protein-transferaseInfo
- Publication number
- NO20022923D0 NO20022923D0 NO20022923A NO20022923A NO20022923D0 NO 20022923 D0 NO20022923 D0 NO 20022923D0 NO 20022923 A NO20022923 A NO 20022923A NO 20022923 A NO20022923 A NO 20022923A NO 20022923 D0 NO20022923 D0 NO 20022923D0
- Authority
- NO
- Norway
- Prior art keywords
- inhibitors
- protein transferase
- farnesyl protein
- farnesyl
- transferase
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/12—Oxygen or sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrrole Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9930317.4A GB9930317D0 (en) | 1999-12-22 | 1999-12-22 | Novel compounds |
| PCT/GB2000/004875 WO2001046138A1 (en) | 1999-12-22 | 2000-12-18 | Inhibitors of farnesyl protein transferase |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO20022923D0 true NO20022923D0 (no) | 2002-06-18 |
| NO20022923L NO20022923L (no) | 2002-06-18 |
Family
ID=10866833
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20022923A NO20022923L (no) | 1999-12-22 | 2002-06-18 | Inhibitorer av farnesyl-protein-transferase |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US6777438B2 (no) |
| EP (1) | EP1242372A1 (no) |
| JP (1) | JP2003518092A (no) |
| KR (1) | KR20020063249A (no) |
| CN (1) | CN1411441A (no) |
| AU (1) | AU2202901A (no) |
| BR (1) | BR0016667A (no) |
| CA (1) | CA2388669A1 (no) |
| GB (1) | GB9930317D0 (no) |
| IL (1) | IL149870A0 (no) |
| MX (1) | MXPA02006110A (no) |
| NO (1) | NO20022923L (no) |
| WO (1) | WO2001046138A1 (no) |
| ZA (1) | ZA200202907B (no) |
Family Cites Families (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1283906C (en) | 1983-05-09 | 1991-05-07 | Makoto Sunagawa | .beta.-LACTAM COMPOUNDS AND PRODUCTION THEREOF |
| JPS60233076A (ja) | 1984-05-03 | 1985-11-19 | Sumitomo Chem Co Ltd | 新規なβ−ラクタム化合物およびその製造法 |
| EP0182213B1 (en) | 1984-11-08 | 1990-09-26 | Sumitomo Pharmaceuticals Company, Limited | Carbapenem compounds and production thereof |
| KR880006244A (ko) | 1986-11-24 | 1988-07-22 | 후지사와 도모 기찌 로 | 3-피롤리디닐티오-1-아자바이스클로[3.2.0]햅트2-엔-2-카르복실산 화합물 및 이의 제조방법 |
| CA2036163C (en) | 1990-02-14 | 2001-06-19 | Makoto Sunagawa | Novel beta-lactam compounds and their production |
| IE910606A1 (en) | 1990-02-23 | 1991-08-28 | Sankyo Co | Carbapenem derivatives having antibiotic activity, their¹preparation and their use |
| GB9107363D0 (en) | 1991-04-08 | 1991-05-22 | Ici Plc | Antibiotic compounds |
| US6083917A (en) | 1990-04-18 | 2000-07-04 | Board Of Regents, The University Of Texas System | Methods and compositions for the identification, characterization and inhibition of farnesyltransferase |
| US5185248A (en) | 1990-05-08 | 1993-02-09 | E. R. Squibb & Sons, Inc. | Farnesyl-protein transferase assay for identifying compounds that block neoplastic transformation |
| GB9107341D0 (en) | 1991-04-08 | 1991-05-22 | Ici Plc | Antibiotic compounds |
| GB9107342D0 (en) | 1991-04-08 | 1991-05-22 | Ici Plc | Antibiotic compounds |
| AU651887B2 (en) | 1991-06-04 | 1994-08-04 | Sankyo Company Limited | 1-methylcarbapenem derivatives, their preparation and their use as antibiotics |
| US5360798A (en) | 1991-07-04 | 1994-11-01 | Shionogi Seiyaku Kabushiki Kaisha | Aminooxypyrrolidinylthiocarbapenem compounds |
| DE69204007T2 (de) | 1991-10-11 | 1996-03-21 | Squibb & Sons Inc | Verwendung von Farnesyl-Protein Transferaseinhibitoren zur Herstellung eines Arzneimittels zur Blockierung von durch Ras-Oncogenen hervorgerufenen neoplastischen Transformationen von Zellen. |
| GB9202298D0 (en) | 1992-02-04 | 1992-03-18 | Ici Plc | Antibiotic compounds |
| FI103046B (fi) | 1992-03-11 | 1999-04-15 | Sankyo Co | Menetelmä lääkeaineina käyttökelpoisten pyrrolidinyylitiokarbapeneemij ohdannaisten valmistamiseksi |
| GB9304156D0 (en) | 1992-03-26 | 1993-04-21 | Zeneca Ltd | Antibiotic compounds |
| CA2091309A1 (en) | 1992-03-26 | 1993-09-27 | Frederic H. Jung | Antibiotic compounds |
| CA2117899A1 (en) | 1992-04-13 | 1993-10-28 | Masayoshi Murata | Substituted 3-pyrrolidinylthio-carbapenems as antimicrobial agents |
| EP0581502B1 (en) | 1992-07-21 | 1998-10-21 | Zeneca Limited | Antibiotic carbapenem compounds |
| CA2099818A1 (en) | 1992-07-21 | 1994-01-22 | Frederic H. Jung | Antibiotic compounds |
| EP0581501B1 (en) | 1992-07-21 | 1998-09-09 | Zeneca Limited | Antibiotic carbapenem compounds |
| EP0590885B1 (en) | 1992-09-28 | 2000-03-15 | Zeneca Limited | Antibiotic carbapenem compounds |
| CA2106330A1 (en) | 1992-10-07 | 1994-04-08 | Patrice J. Siret | Antibiotic compounds |
| CA2118985A1 (en) | 1993-04-02 | 1994-10-03 | Dinesh V. Patel | Heterocyclic inhibitors of farnesyl protein transferase |
| WO1995000497A1 (en) | 1993-06-18 | 1995-01-05 | Merck & Co., Inc. | Inhibitors of farnesyl-protein transferase |
| AU678625B2 (en) | 1993-09-30 | 1997-06-05 | Merck & Co., Inc. | Inhibitors of farnesyl-protein transferase |
| US5468733A (en) | 1993-09-30 | 1995-11-21 | Merck & Co., Inc. | Inhibitors of farnesyl-protein transferase |
| CA2185441A1 (en) | 1994-03-15 | 1995-09-21 | Michael D. Lewis | Isoprenyl transferase inhibitors |
| CA2155448A1 (en) | 1994-08-11 | 1996-02-12 | Katerina Leftheris | Inhibitors of farnesyl protein transferase |
| US5571835A (en) | 1994-09-29 | 1996-11-05 | Merck & Co., Inc. | Inhibitors of farnesyl-protein transferase |
| ES2196163T3 (es) | 1995-07-31 | 2003-12-16 | Shionogi & Co | Derivados de pirrolidina con una actividad de inhibicion de la fosfolipasa a2. |
| GB9515975D0 (en) | 1995-08-04 | 1995-10-04 | Zeneca Ltd | Chemical compounds |
| AU4020897A (en) | 1996-08-17 | 1998-03-06 | Zeneca Limited | 3-mercaptopyrrolidines as farnesyl protein transferase inhibitors |
| US6414145B1 (en) | 1997-01-29 | 2002-07-02 | Zeneca Limited | Imidazolyl compounds as inhibitors of farnesyl-protein tranferase |
| AU7371998A (en) * | 1997-05-07 | 1998-11-27 | University Of Pittsburgh | Inhibitors of protein isoprenyl transferases |
| US6342765B1 (en) | 1997-10-22 | 2002-01-29 | Astrazeneca Uk Limited | Imidazole derivatives and their use as farnesyl protein transferase inhibitors |
| WO1999041235A1 (en) | 1998-02-10 | 1999-08-19 | Astrazeneca Uk Limited | Farnesyl transferase inhibitors |
| US6486156B1 (en) | 1998-12-23 | 2002-11-26 | Astrazeneca Ab | Chemical compounds |
| DE19961894A1 (de) | 1999-12-20 | 2001-06-21 | Basf Ag | Transparente, schlagzähe thermoplastische Formmassen |
-
1999
- 1999-12-22 GB GBGB9930317.4A patent/GB9930317D0/en not_active Ceased
-
2000
- 2000-12-18 AU AU22029/01A patent/AU2202901A/en not_active Abandoned
- 2000-12-18 MX MXPA02006110A patent/MXPA02006110A/es active IP Right Grant
- 2000-12-18 IL IL14987000A patent/IL149870A0/xx unknown
- 2000-12-18 CA CA002388669A patent/CA2388669A1/en not_active Abandoned
- 2000-12-18 BR BR0016667-7A patent/BR0016667A/pt not_active IP Right Cessation
- 2000-12-18 JP JP2001547049A patent/JP2003518092A/ja active Pending
- 2000-12-18 WO PCT/GB2000/004875 patent/WO2001046138A1/en not_active Application Discontinuation
- 2000-12-18 CN CN00817419A patent/CN1411441A/zh active Pending
- 2000-12-18 US US10/168,379 patent/US6777438B2/en not_active Expired - Fee Related
- 2000-12-18 EP EP00985621A patent/EP1242372A1/en not_active Withdrawn
- 2000-12-18 KR KR1020027008023A patent/KR20020063249A/ko not_active Application Discontinuation
-
2002
- 2002-04-12 ZA ZA200202907A patent/ZA200202907B/en unknown
- 2002-06-18 NO NO20022923A patent/NO20022923L/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US6777438B2 (en) | 2004-08-17 |
| WO2001046138A1 (en) | 2001-06-28 |
| MXPA02006110A (es) | 2002-12-05 |
| GB9930317D0 (en) | 2000-02-09 |
| CN1411441A (zh) | 2003-04-16 |
| ZA200202907B (en) | 2003-07-14 |
| KR20020063249A (ko) | 2002-08-01 |
| EP1242372A1 (en) | 2002-09-25 |
| IL149870A0 (en) | 2002-11-10 |
| AU2202901A (en) | 2001-07-03 |
| US20030096842A1 (en) | 2003-05-22 |
| BR0016667A (pt) | 2002-09-03 |
| CA2388669A1 (en) | 2001-06-28 |
| JP2003518092A (ja) | 2003-06-03 |
| NO20022923L (no) | 2002-06-18 |
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