NO20020622L - Polymorfer av torsemid - Google Patents
Polymorfer av torsemidInfo
- Publication number
- NO20020622L NO20020622L NO20020622A NO20020622A NO20020622L NO 20020622 L NO20020622 L NO 20020622L NO 20020622 A NO20020622 A NO 20020622A NO 20020622 A NO20020622 A NO 20020622A NO 20020622 L NO20020622 L NO 20020622L
- Authority
- NO
- Norway
- Prior art keywords
- torsemide
- polymorphs
- Prior art date
Links
- NGBFQHCMQULJNZ-UHFFFAOYSA-N Torsemide Chemical compound CC(C)NC(=O)NS(=O)(=O)C1=CN=CC=C1NC1=CC=CC(C)=C1 NGBFQHCMQULJNZ-UHFFFAOYSA-N 0.000 title 1
- 229960005461 torasemide Drugs 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/64—Sulfonylureas, e.g. glibenclamide, tolbutamide, chlorpropamide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pyridine Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Details Of Garments (AREA)
- Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
- Pressure Welding/Diffusion-Bonding (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US14830599P | 1999-08-11 | 1999-08-11 | |
| US18312700P | 2000-02-17 | 2000-02-17 | |
| US21527300P | 2000-06-30 | 2000-06-30 | |
| PCT/US2000/022081 WO2001010441A1 (en) | 1999-08-11 | 2000-08-11 | Torsemide polymorphs |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO20020622D0 NO20020622D0 (no) | 2002-02-08 |
| NO20020622L true NO20020622L (no) | 2002-03-14 |
Family
ID=27386674
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20020622A NO20020622L (no) | 1999-08-11 | 2002-02-08 | Polymorfer av torsemid |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US6465496B1 (enExample) |
| EP (1) | EP1207880A4 (enExample) |
| JP (1) | JP2003527319A (enExample) |
| KR (1) | KR20020025217A (enExample) |
| CN (1) | CN1378448A (enExample) |
| AU (1) | AU781461C (enExample) |
| BG (1) | BG106400A (enExample) |
| CA (1) | CA2379322A1 (enExample) |
| CZ (1) | CZ2002404A3 (enExample) |
| DE (1) | DE00957398T1 (enExample) |
| ES (1) | ES2204354T1 (enExample) |
| HK (1) | HK1046636A1 (enExample) |
| HR (1) | HRP20020120A2 (enExample) |
| HU (1) | HUP0204318A3 (enExample) |
| IL (1) | IL148031A0 (enExample) |
| LT (1) | LT5004B (enExample) |
| MX (1) | MXPA02001369A (enExample) |
| NO (1) | NO20020622L (enExample) |
| PL (1) | PL354262A1 (enExample) |
| SI (1) | SI20816A (enExample) |
| SK (1) | SK1912002A3 (enExample) |
| TR (1) | TR200200353T2 (enExample) |
| WO (1) | WO2001010441A1 (enExample) |
| YU (1) | YU9502A (enExample) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SK11632003A3 (sk) * | 2000-02-17 | 2004-04-06 | Teva Pharmaceutical Industries Ltd. | Stabilný farmaceutický prípravok obsahujúci modifikáciu II torsemidu |
| DE10013289A1 (de) * | 2000-03-17 | 2001-09-20 | Knoll Ag | Torasemid enthaltende pharmazeutische Zubereitungen |
| HRP20000162B1 (en) | 2000-03-20 | 2004-06-30 | Pliva D D | Amorphous torasemide modification |
| US20030022921A1 (en) * | 2001-02-21 | 2003-01-30 | Minutza Leibovici | Stable pharmaceutical formulation comprising torsemide modification II |
| EP1397343A1 (en) | 2001-05-31 | 2004-03-17 | Orion Corporation Fermion | Process for preparing sertraline hydrochloride polymorphic form ii |
| IN192178B (enExample) | 2001-08-03 | 2004-03-06 | Ranbaxy Lab | |
| US20030119882A1 (en) * | 2001-10-22 | 2003-06-26 | Markus Maegerlein | Solid pharmaceutical composition containing torasemide |
| ITMI20020639A1 (it) * | 2002-03-27 | 2003-09-29 | Cosma S P A | Composizioni farmaceutiche comprendenti come principio attivo 1-isopropil-3°(4-m-toluidino-3-pridil)sulfonil!-urea |
| HRP20020603B1 (en) * | 2002-07-19 | 2008-11-30 | Pliva D.D. | New process for the preparation of modification i n-(1-methylethylaminocarbonyl)-4-(3-methylphenylamino)-3-pyridinesulfonamide |
| CA2424644A1 (en) * | 2003-04-07 | 2004-10-07 | David John Mckenzie | Preparation of torasemide |
| ES2244324B1 (es) * | 2004-03-25 | 2006-11-16 | Ferrer Internacional, S.A. | Composiciones diureticas de liberacion prolongada. |
| AT500576B1 (de) * | 2004-07-28 | 2006-11-15 | Sanochemia Pharmazeutika Ag | Verfahren zur reindarstellung von kristallformen von torsemid |
| KR100845383B1 (ko) * | 2004-12-24 | 2008-07-09 | 일동제약주식회사 | 토르세미드 변형체(ⅰ)의 제조방법 |
| US20070122483A1 (en) * | 2005-11-29 | 2007-05-31 | Sharon Myers | Fluocinolone acetonide drug substance polymorphic interconversion |
| AU2014348523B2 (en) | 2013-11-15 | 2019-01-03 | Akebia Therapeutics, Inc. | Solid forms of {[5-(3-chlorophenyl)-3-hydroxypyridine-2-carbonyl]amino}acetic acid, compositions, and uses thereof |
| CN105949115A (zh) * | 2016-05-26 | 2016-09-21 | 南京正科医药股份有限公司 | 一种新晶型托拉塞米 |
| CN115417810B (zh) * | 2022-09-22 | 2023-10-10 | 南京正科医药股份有限公司 | 一种托拉塞米晶型ⅰ的精制方法 |
| CN117486789A (zh) * | 2023-12-29 | 2024-02-02 | 江西中医药大学 | 一种托拉塞米共晶盐及其制备方法和应用 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US30633A (en) | 1860-11-13 | Improvement in fire-escapes | ||
| US34672A (en) | 1862-03-18 | Improved convertible boat, bridge, and tent | ||
| GB1477664A (en) | 1974-04-17 | 1977-06-22 | Christiaens Sa A | Pyridine derivatives |
| US4055650A (en) | 1974-04-17 | 1977-10-25 | A. Christiaens Societe Anonyme | Certain 4-phenoxy(or phenylthio)-3-n-acylated-sulfonamido-pyridines |
| DE3529529A1 (de) * | 1985-08-17 | 1987-02-19 | Boehringer Mannheim Gmbh | Verfahren zur herstellung einer stabilen modifikation von torasemid |
| DE3623620A1 (de) | 1986-07-12 | 1988-01-21 | Boehringer Mannheim Gmbh | Spritzfertige, waessrige, alkalische injektionsloesungen von torasemid und verfahren zu ihrer herstellung |
| HRP980532B1 (en) * | 1998-10-02 | 2005-06-30 | Pliva | Novel crystalline torasemide modification |
| US5914336A (en) * | 1998-06-02 | 1999-06-22 | Boehringer Mannheim Gmbh | Method of controlling the serum solubility of orally administered torasemide and composition relating thereto |
| US6166045A (en) * | 1998-06-02 | 2000-12-26 | Roche Diagnostics Gmbh | Torasemide of modification III |
| HRP20000162B1 (en) * | 2000-03-20 | 2004-06-30 | Pliva D D | Amorphous torasemide modification |
| CA2403382A1 (en) * | 2000-03-20 | 2001-09-27 | Teva Pharmaceutical Industries Ltd. | Novel processes for preparing torsemide intermediate |
| HRP20000328A2 (en) * | 2000-05-19 | 2002-02-28 | Pliva Farmaceutska Ind Dionik | Novel polymorph v of torasemide |
-
2000
- 2000-08-11 HR HR20020120A patent/HRP20020120A2/hr not_active Application Discontinuation
- 2000-08-11 WO PCT/US2000/022081 patent/WO2001010441A1/en not_active Ceased
- 2000-08-11 EP EP00957398A patent/EP1207880A4/en not_active Withdrawn
- 2000-08-11 DE DE0001207880T patent/DE00957398T1/de active Pending
- 2000-08-11 PL PL00354262A patent/PL354262A1/xx not_active Application Discontinuation
- 2000-08-11 HK HK02108111.5A patent/HK1046636A1/zh unknown
- 2000-08-11 AU AU69026/00A patent/AU781461C/en not_active Ceased
- 2000-08-11 TR TR2002/00353T patent/TR200200353T2/xx unknown
- 2000-08-11 KR KR1020027001867A patent/KR20020025217A/ko not_active Ceased
- 2000-08-11 MX MXPA02001369A patent/MXPA02001369A/es unknown
- 2000-08-11 US US09/638,106 patent/US6465496B1/en not_active Expired - Fee Related
- 2000-08-11 SK SK191-2002A patent/SK1912002A3/sk unknown
- 2000-08-11 CN CN00814045A patent/CN1378448A/zh active Pending
- 2000-08-11 CA CA002379322A patent/CA2379322A1/en not_active Abandoned
- 2000-08-11 SI SI200020037A patent/SI20816A/sl not_active IP Right Cessation
- 2000-08-11 CZ CZ2002404A patent/CZ2002404A3/cs unknown
- 2000-08-11 JP JP2001514958A patent/JP2003527319A/ja not_active Withdrawn
- 2000-08-11 ES ES00957398T patent/ES2204354T1/es active Pending
- 2000-08-11 IL IL14803100A patent/IL148031A0/xx unknown
- 2000-08-11 HU HU0204318A patent/HUP0204318A3/hu unknown
- 2000-08-11 YU YU9502A patent/YU9502A/sh unknown
-
2002
- 2002-02-08 NO NO20020622A patent/NO20020622L/no not_active Application Discontinuation
- 2002-02-08 BG BG106400A patent/BG106400A/xx unknown
- 2002-02-11 LT LT2002017A patent/LT5004B/lt unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ES2204354T1 (es) | 2004-05-01 |
| US6465496B1 (en) | 2002-10-15 |
| HUP0204318A3 (en) | 2005-03-29 |
| CA2379322A1 (en) | 2001-02-15 |
| JP2003527319A (ja) | 2003-09-16 |
| IL148031A0 (en) | 2002-09-12 |
| MXPA02001369A (es) | 2005-08-26 |
| HK1046636A1 (zh) | 2003-01-24 |
| PL354262A1 (en) | 2003-12-29 |
| NO20020622D0 (no) | 2002-02-08 |
| CZ2002404A3 (cs) | 2002-06-12 |
| EP1207880A1 (en) | 2002-05-29 |
| AU781461B2 (en) | 2005-05-26 |
| AU781461C (en) | 2006-02-23 |
| CN1378448A (zh) | 2002-11-06 |
| SK1912002A3 (en) | 2002-07-02 |
| EP1207880A4 (en) | 2004-09-01 |
| WO2001010441A1 (en) | 2001-02-15 |
| LT2002017A (en) | 2002-11-25 |
| HUP0204318A2 (en) | 2003-05-28 |
| DE00957398T1 (de) | 2004-04-15 |
| TR200200353T2 (tr) | 2002-06-21 |
| HRP20020120A2 (en) | 2003-10-31 |
| LT5004B (lt) | 2003-03-25 |
| SI20816A (sl) | 2002-08-31 |
| BG106400A (en) | 2002-08-30 |
| KR20020025217A (ko) | 2002-04-03 |
| YU9502A (sh) | 2005-06-10 |
| AU6902600A (en) | 2001-03-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |