NO20015465L - Spraytörking av trombin-inhibitorer - Google Patents

Spraytörking av trombin-inhibitorer

Info

Publication number
NO20015465L
NO20015465L NO20015465A NO20015465A NO20015465L NO 20015465 L NO20015465 L NO 20015465L NO 20015465 A NO20015465 A NO 20015465A NO 20015465 A NO20015465 A NO 20015465A NO 20015465 L NO20015465 L NO 20015465L
Authority
NO
Norway
Prior art keywords
thrombin inhibitors
spray drying
tautomers
formula
preparation
Prior art date
Application number
NO20015465A
Other languages
English (en)
Other versions
NO20015465D0 (no
Inventor
Bernd Schaefer
Guido Harms
Hermann Ascherl
Georg Arnold Krei
Original Assignee
Basf Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Ag filed Critical Basf Ag
Publication of NO20015465D0 publication Critical patent/NO20015465D0/no
Publication of NO20015465L publication Critical patent/NO20015465L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06078—Dipeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Application Of Or Painting With Fluid Materials (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Oppfinnelsen vedrører en fremgangsmåte for fremstilling av trombin-inhibitorer som har en konstant vekt og som har formel (l), hvori n representerer O, 1, 2, og tautomerene derav, hvorved en vandig løsning av den aktive substans sprøytetørkes.
NO20015465A 1999-05-10 2001-11-08 Spraytörking av trombin-inhibitorer NO20015465L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19921346A DE19921346A1 (de) 1999-05-10 1999-05-10 Sprühtrocknung von Thrombininhibitoren
PCT/EP2000/003965 WO2000068254A1 (de) 1999-05-10 2000-05-03 Sprühtrocknung von thrombininhibitoren

Publications (2)

Publication Number Publication Date
NO20015465D0 NO20015465D0 (no) 2001-11-08
NO20015465L true NO20015465L (no) 2001-11-09

Family

ID=7907478

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20015465A NO20015465L (no) 1999-05-10 2001-11-08 Spraytörking av trombin-inhibitorer

Country Status (20)

Country Link
US (1) US6693120B1 (no)
EP (1) EP1177208A1 (no)
JP (1) JP2003501349A (no)
KR (1) KR20020010647A (no)
CN (1) CN1350545A (no)
AU (1) AU4560900A (no)
BG (1) BG106089A (no)
BR (1) BR0010440A (no)
CA (1) CA2373068A1 (no)
CZ (1) CZ20014039A3 (no)
DE (1) DE19921346A1 (no)
HK (1) HK1045530A1 (no)
HU (1) HUP0201286A3 (no)
IL (1) IL146361A0 (no)
NO (1) NO20015465L (no)
PL (1) PL351668A1 (no)
RU (1) RU2001133346A (no)
SK (1) SK16172001A3 (no)
TR (1) TR200103246T2 (no)
WO (1) WO2000068254A1 (no)

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE261162C (no)
GB956944A (en) 1962-06-22 1964-04-29 Commercial Solvents Corp Improved method of preparing free flowing materials containing chloine chloride
FR2097079A1 (en) 1970-07-31 1972-03-03 Melle Usine De Aluminium n-acetyl glycinates - by spray-drying of solns
EP0040472B1 (en) 1980-05-20 1986-01-29 Mallinckrodt, Inc. (a Delaware corporation) Spray dried n-acetyl-p-aminophenol compositions and method for manufacture thereof
DD261162A1 (de) * 1986-03-11 1988-10-19 Jenapharm Veb Verfahren zur isolierung von pharmazeutisch verwendbarem cloxacillin-natrium
US4861591A (en) 1987-11-18 1989-08-29 American Home Products Corporation Formulations for hygroscopic pharmaceuticals
DE4315878A1 (de) 1993-05-12 1994-11-17 Basf Ag Magnesiumsalz von 3-Isopropyl-2,1,3-benzothiadiazin-4-on-2,2 -dioxid, Verfahren zu seiner Herstellung und seine Verwendung zur Bekämpfung von unerwünschtem Pflanzenwuchs
MX9706069A (es) 1995-02-17 1997-10-31 Basf Ag Nuevos inhibidores de la trombina.
ATE279435T1 (de) * 1999-05-10 2004-10-15 Abbott Gmbh & Co Kg Salze von thrombininhibitoren

Also Published As

Publication number Publication date
DE19921346A1 (de) 2000-11-16
CA2373068A1 (en) 2000-11-16
AU4560900A (en) 2000-11-21
PL351668A1 (en) 2003-05-19
SK16172001A3 (sk) 2002-06-04
BG106089A (en) 2002-06-28
NO20015465D0 (no) 2001-11-08
KR20020010647A (ko) 2002-02-04
TR200103246T2 (tr) 2002-04-22
CN1350545A (zh) 2002-05-22
CZ20014039A3 (cs) 2003-02-12
WO2000068254A1 (de) 2000-11-16
HUP0201286A2 (en) 2002-09-28
IL146361A0 (en) 2002-07-25
HK1045530A1 (zh) 2002-11-29
JP2003501349A (ja) 2003-01-14
BR0010440A (pt) 2002-02-19
RU2001133346A (ru) 2004-01-20
US6693120B1 (en) 2004-02-17
HUP0201286A3 (en) 2002-11-28
EP1177208A1 (de) 2002-02-06

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Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application