NO20005328L - Fosfonsyrediesterderivater - Google Patents

Fosfonsyrediesterderivater

Info

Publication number
NO20005328L
NO20005328L NO20005328A NO20005328A NO20005328L NO 20005328 L NO20005328 L NO 20005328L NO 20005328 A NO20005328 A NO 20005328A NO 20005328 A NO20005328 A NO 20005328A NO 20005328 L NO20005328 L NO 20005328L
Authority
NO
Norway
Prior art keywords
lower alkyl
amino
represent
carbon atoms
hydrogen
Prior art date
Application number
NO20005328A
Other languages
English (en)
Norwegian (no)
Other versions
NO20005328D0 (no
Inventor
Yasuhiro Sakai
Kazuyoshi Miyata
Kenichi Kawamura
Yoshihiko Tsuda
Yasuhide Inoue
Original Assignee
Otsuka Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Pharma Co Ltd filed Critical Otsuka Pharma Co Ltd
Publication of NO20005328D0 publication Critical patent/NO20005328D0/no
Publication of NO20005328L publication Critical patent/NO20005328L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/38Phosphonic acids RP(=O)(OH)2; Thiophosphonic acids, i.e. RP(=X)(XH)2 (X = S, Se)
    • C07F9/40Esters thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/38Phosphonic acids RP(=O)(OH)2; Thiophosphonic acids, i.e. RP(=X)(XH)2 (X = S, Se)
    • C07F9/40Esters thereof
    • C07F9/4003Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/4062Esters of acids containing the structure -C(=X)-P(=X)(XR)2 or NC-P(=X)(XR)2, (X = O, S, Se)
    • C07F9/4065Esters of acids containing the structure -C(=X)-P(=X)(XR)2, (X = O, S, Se)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/38Phosphonic acids RP(=O)(OH)2; Thiophosphonic acids, i.e. RP(=X)(XH)2 (X = S, Se)
    • C07F9/40Esters thereof
    • C07F9/4003Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/4006Esters of acyclic acids which can have further substituents on alkyl
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/576Six-membered rings
    • C07F9/58Pyridine rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/645Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
    • C07F9/6509Six-membered rings
    • C07F9/650952Six-membered rings having the nitrogen atoms in the positions 1 and 4

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Diabetes (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Lubricants (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
NO20005328A 1998-04-24 2000-10-23 Fosfonsyrediesterderivater NO20005328L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP11553698A JP4032193B2 (ja) 1998-04-24 1998-04-24 ホスホン酸ジエステル誘導体
PCT/JP1999/002114 WO1999055713A1 (fr) 1998-04-24 1999-04-21 Derives de diester phosphonique

Publications (2)

Publication Number Publication Date
NO20005328D0 NO20005328D0 (no) 2000-10-23
NO20005328L true NO20005328L (no) 2000-12-22

Family

ID=14664971

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20005328A NO20005328L (no) 1998-04-24 2000-10-23 Fosfonsyrediesterderivater

Country Status (12)

Country Link
US (1) US6468992B1 (zh)
EP (1) EP1074556B1 (zh)
JP (1) JP4032193B2 (zh)
KR (1) KR100753378B1 (zh)
CN (1) CN1177852C (zh)
AT (1) ATE251632T1 (zh)
AU (1) AU756940B2 (zh)
CA (1) CA2330111A1 (zh)
DE (1) DE69911946T2 (zh)
NO (1) NO20005328L (zh)
TW (1) TWI230711B (zh)
WO (1) WO1999055713A1 (zh)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL132315A0 (en) * 1999-10-11 2001-03-19 Yissum Res Dev Co Compositions comprising oxophosphonate-based metalloproteinase inhibitors
US7956360B2 (en) * 2004-06-03 2011-06-07 The Regents Of The University Of California Growth of planar reduced dislocation density M-plane gallium nitride by hydride vapor phase epitaxy
CN101490064B (zh) * 2006-07-06 2012-10-10 百时美施贵宝公司 新颖葡萄糖激酶活化剂及其使用方法
US7910747B2 (en) 2006-07-06 2011-03-22 Bristol-Myers Squibb Company Phosphonate and phosphinate pyrazolylamide glucokinase activators
US8993544B2 (en) 2009-02-09 2015-03-31 Yissum Research Development Company Of The Hebrew University Of Jerusalem, Ltd. Carbamoylphosphonates as inhibitors and uses thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2835547B2 (ja) * 1991-12-25 1998-12-14 株式会社大塚製薬工場 糖尿病治療剤
KR100324866B1 (ko) * 1995-12-27 2002-10-19 가부시키가이샤오쓰카세이야쿠코죠 포스폰산디에스테르유도체
JP3785514B2 (ja) 1996-02-20 2006-06-14 株式会社大塚製薬工場 ホスホン酸ジエステル誘導体

Also Published As

Publication number Publication date
KR100753378B1 (ko) 2007-08-30
ATE251632T1 (de) 2003-10-15
AU756940B2 (en) 2003-01-30
EP1074556A1 (en) 2001-02-07
NO20005328D0 (no) 2000-10-23
CA2330111A1 (en) 1999-11-04
AU3533999A (en) 1999-11-16
US6468992B1 (en) 2002-10-22
EP1074556B1 (en) 2003-10-08
JPH11302291A (ja) 1999-11-02
JP4032193B2 (ja) 2008-01-16
CN1177852C (zh) 2004-12-01
DE69911946D1 (de) 2003-11-13
WO1999055713A1 (fr) 1999-11-04
CN1296489A (zh) 2001-05-23
KR20010042580A (ko) 2001-05-25
EP1074556A4 (en) 2002-04-24
TWI230711B (en) 2005-04-11
DE69911946T2 (de) 2004-05-13

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Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application