NO20004089L - Nye triazolo(4,5-d)pyrimidinforbindelser - Google Patents

Nye triazolo(4,5-d)pyrimidinforbindelser

Info

Publication number
NO20004089L
NO20004089L NO20004089A NO20004089A NO20004089L NO 20004089 L NO20004089 L NO 20004089L NO 20004089 A NO20004089 A NO 20004089A NO 20004089 A NO20004089 A NO 20004089A NO 20004089 L NO20004089 L NO 20004089L
Authority
NO
Norway
Prior art keywords
pyrimidine compounds
new triazolo
triazolo
new
pyrimidine
Prior art date
Application number
NO20004089A
Other languages
English (en)
Other versions
NO20004089D0 (no
Inventor
Roger Brown
Garry Pairaudeau
Brian Springthorpe
Stephen Thom
Paul Willis
Original Assignee
Astrazeneca Uk Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from SE9800458A external-priority patent/SE9800458D0/xx
Priority claimed from SE9803669A external-priority patent/SE9803669D0/xx
Application filed by Astrazeneca Uk Ltd filed Critical Astrazeneca Uk Ltd
Publication of NO20004089D0 publication Critical patent/NO20004089D0/no
Publication of NO20004089L publication Critical patent/NO20004089L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

Abstract

Det er beskrevet nye triazolo[4,5-c/]pyrimidinforbindelser ifølge formel (I), anvendelse derav som medikamenter, sammensetninger som inneholder dem og fremgangsmåter for deres fremstilling.
NO20004089A 1998-02-17 2000-08-16 Nye triazolo(4,5-d)pyrimidinforbindelser NO20004089L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE9800458A SE9800458D0 (sv) 1998-02-17 1998-02-17 Novel compounds
SE9803669A SE9803669D0 (sv) 1998-10-26 1998-10-26 Novel compounds
PCT/SE1999/000154 WO1999041254A1 (en) 1998-02-17 1999-02-05 NOVEL TRIAZOLO(4,5-d)PYRIMIDINE COMPOUNDS

Publications (2)

Publication Number Publication Date
NO20004089D0 NO20004089D0 (no) 2000-08-16
NO20004089L true NO20004089L (no) 2000-10-16

Family

ID=26663214

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20004089A NO20004089L (no) 1998-02-17 2000-08-16 Nye triazolo(4,5-d)pyrimidinforbindelser

Country Status (21)

Country Link
US (1) US6369064B1 (no)
EP (1) EP1056749B1 (no)
JP (1) JP2002503663A (no)
KR (1) KR20010078696A (no)
CN (1) CN1291193A (no)
AR (1) AR015515A1 (no)
AT (1) ATE232866T1 (no)
AU (1) AU2650099A (no)
BR (1) BR9907934A (no)
CA (1) CA2316264A1 (no)
DE (1) DE69905451T2 (no)
HU (1) HUP0100328A3 (no)
ID (1) ID27127A (no)
IL (1) IL137812A0 (no)
MX (1) MXPA00007634A (no)
NO (1) NO20004089L (no)
NZ (1) NZ505250A (no)
PL (1) PL342430A1 (no)
SK (1) SK12242000A3 (no)
TR (1) TR200002380T2 (no)
WO (1) WO1999041254A1 (no)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9702773D0 (sv) * 1997-07-22 1997-07-22 Astra Pharma Prod Novel compounds
SE9904129D0 (sv) 1999-11-15 1999-11-15 Astra Pharma Prod Novel compounds
GB0013488D0 (en) * 2000-06-02 2000-07-26 Astrazeneca Ab Chemical compound
TWI290549B (en) * 2000-06-02 2007-12-01 Astrazeneca Ab Process for the preparation of cyclopropyl carboxylic acid ester and derivatives
US7086397B2 (en) * 2002-02-16 2006-08-08 Graham Lindley Spruiell Patient usable emergency medical kit
GB0219746D0 (en) * 2002-08-23 2002-10-02 Inst Of Ex Botany Ascr Azapurine derivatives
US7335648B2 (en) 2003-10-21 2008-02-26 Inspire Pharmaceuticals, Inc. Non-nucleotide composition and method for inhibiting platelet aggregation
US7504497B2 (en) 2003-10-21 2009-03-17 Inspire Pharmaceuticals, Inc. Orally bioavailable compounds and methods for inhibiting platelet aggregation
US7749981B2 (en) 2003-10-21 2010-07-06 Inspire Pharmaceuticals, Inc. Drug-eluting stents coated with non-nucleotide P2Y12 receptor antagonist compound
WO2005040174A1 (en) 2003-10-21 2005-05-06 Inspire Pharmaceuticals, Inc. Tetrahydro-furo`3,4-d!dioxole compounds and compositions and method for inhibiting platelet aggregation
US7932376B2 (en) 2005-05-05 2011-04-26 Inspire Pharmaceuticals, Inc. Pyrimidine-based non-nucleotide composition and method for inhibiting platelet aggregation
JPWO2007020935A1 (ja) * 2005-08-17 2009-02-26 小野薬品工業株式会社 Ｐ２ｙ１２受容体および／またはｐ２ｙ１４受容体ブロッカーを含有してなる疼痛治療剤
JP2010508350A (ja) * 2006-10-31 2010-03-18 ヤンセン ファーマシューティカ エヌ．ベー． Ａｄｐｐ２ｙ１２レセプターアンタゴニストとしてのトリアゾロピリミジン誘導体
EP2340252B1 (en) * 2008-09-09 2015-11-11 AstraZeneca AB A process for preparing [1s- ]1-alpha, 2-alpha, 3-beta (1s*, 2r*) 5-beta] ]-3- [7- [2- (3, 4-dif luorophenyl) -cyclopropylamino]- 5- (propylthio) -3h-1, 2, 3-triazolo [4, 5-d]pyrimidin-3-yl]-5- (2- hydroxyethoxy) cyclopentane-1, 2-diol and to its intermediates
WO2015027431A1 (en) * 2013-08-29 2015-03-05 Merck Sharp & Dohme Corp. 2,2-difluorodioxolo a2a receptor antagonists
WO2015162630A1 (en) * 2014-04-25 2015-10-29 Anlon Chemical Research Organization Novel processes for preparing triazolo [4,5-d]- pyrimidines, including ticagrelor, vianew intermediates and new route of synthesis.
MX2018011453A (es) 2016-03-22 2019-01-10 Merck Sharp & Dohme Moduladores alostericos de receptores de acetilcolina nicotinicos.
CN111116592A (zh) * 2019-11-27 2020-05-08 杭州沧海帆医药科技有限公司 嘧啶并三氮唑类化合物及其医药用途
CN112876485A (zh) * 2021-01-25 2021-06-01 郭丽伟 一种用于治疗子宫平滑肌高频率强直性收缩相关疾病的化合物
EP4436566A1 (en) * 2021-11-22 2024-10-02 Purdue Research Foundation Cell-potent bisubstrate inhibitors for nicotinamide n-methyltransferase (nnmt) and uses thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4742064A (en) 1985-09-10 1988-05-03 Regents Of The University Of Minnesota Antiviral carbocyclic analogs of xylofuranosylpurines
GB8826205D0 (en) 1988-11-09 1988-12-14 Wellcome Found Heterocyclic compounds
US5747496A (en) * 1995-07-11 1998-05-05 Astra Pharmaceuticals Limited Inhibitors of platelet aggregation
EP0946561B1 (en) 1996-12-20 2002-02-13 AstraZeneca AB Triazolo(4,5-d)pyrimidinyl derivatives and their use as medicaments
SE9702774D0 (sv) * 1997-07-22 1997-07-22 Astra Pharma Prod Novel compounds
SE9702772D0 (sv) * 1997-07-22 1997-07-22 Astra Pharma Prod Novel compounds

Also Published As

Publication number Publication date
TR200002380T2 (tr) 2001-03-21
JP2002503663A (ja) 2002-02-05
DE69905451T2 (de) 2003-11-20
HUP0100328A3 (en) 2003-04-28
DE69905451D1 (de) 2003-03-27
ATE232866T1 (de) 2003-03-15
HUP0100328A2 (hu) 2001-09-28
WO1999041254A1 (en) 1999-08-19
NO20004089D0 (no) 2000-08-16
NZ505250A (en) 2002-10-25
EP1056749B1 (en) 2003-02-19
KR20010078696A (ko) 2001-08-21
US6369064B1 (en) 2002-04-09
EP1056749A1 (en) 2000-12-06
AU2650099A (en) 1999-08-30
MXPA00007634A (es) 2003-09-10
IL137812A0 (en) 2001-10-31
CA2316264A1 (en) 1999-08-19
BR9907934A (pt) 2000-10-24
CN1291193A (zh) 2001-04-11
SK12242000A3 (sk) 2001-03-12
AR015515A1 (es) 2001-05-02
ID27127A (id) 2001-03-01
PL342430A1 (en) 2001-06-04

Similar Documents

Publication Publication Date Title
NO20004089L (no) Nye triazolo(4,5-d)pyrimidinforbindelser
NO20000311L (no) Nye forbindelser
NO20000313L (no) Nye forbindelser
UA66801C2 (uk) Триазоло[4,5-d]піримідинові сполуки, спосіб їх одержання (варіанти), фармацевтична композиція на їх основі та спосіб лікування порушень агрегації тромбоцитів
TR200101567T2 (tr) Yeni triazolo(4.5-D)pirimidin bileşimleri.
MY148652A (en) New crystalline form of a triazolo(4,5-d)pyrimidine compound
AU2002305143A1 (en) Pyrazolo'1,5-a!pyridine derivatives
NO992821L (no) Ketobenzamider som calpain-inhibitorer
AU2002239344A1 (en) Pyrazolopyridines
NO20050668L (no) 7,8,9,10-tetrahydro-6H-azepino6,7,8,9-tetrahydro-pyrido og 2,3-dihydro-2H-pyrrolo [2,1-B]-kinazolinon-derivater
NO20055092L (no) Substituerte pyrimidioner
NO20050635L (no) Nye tricykliske spiropiperidiner eller spiropyrrolidiner
NO20006521L (no) 2-(purin-9-yl)-tetrahydrofuran-3,4-diol-derivater
IL158667A0 (en) Imidazo [1,2-a] pyridine derivatives for the prophylaxis and treatment of herpes viral infections
AU2003228770A1 (en) Substituted pyrazolopyrimidines
NO993027L (no) Pyrrolo[3,4-D]pyrimidinonderivater og deres anvendelse som legemidler
AU2002239348A1 (en) Pyrazolopyridine derivatives
NO20070570L (no) Forbindelser.
SE9904129D0 (sv) Novel compounds
SE9802574D0 (sv) Novel compounds
NO20023001L (no) Substituerte piperazinderivater som MTP inhibitorer
BRPI0210746B8 (pt) derivados de 6-'2-(fosfonometóxi)alcóxi-pirimidina e seu método de preparação
ATE213241T1 (de) Amidin- und isothioharnstoffderivate als inhibitoren der stickstoffoxid-synthase
SE9904128D0 (sv) Novel compounds
AU2002357740A1 (en) Pyrazolo-pyridine derivatives as antiherpes agents

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application