NO180297C - Nonionic iodinated compounds and contrast agents containing the same - Google Patents

Nonionic iodinated compounds and contrast agents containing the same

Info

Publication number
NO180297C
NO180297C NO913403A NO913403A NO180297C NO 180297 C NO180297 C NO 180297C NO 913403 A NO913403 A NO 913403A NO 913403 A NO913403 A NO 913403A NO 180297 C NO180297 C NO 180297C
Authority
NO
Norway
Prior art keywords
same
contrast agents
agents containing
iodinated compounds
nonionic iodinated
Prior art date
Application number
NO913403A
Other languages
Norwegian (no)
Other versions
NO913403D0 (en
NO180297B (en
NO913403L (en
Inventor
Michel Schaefer
Maryse Dugast-Zrihen
Michel Guillemot
Didier Doucet
Dominique Meyer
Original Assignee
Guerbet Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Guerbet Sa filed Critical Guerbet Sa
Publication of NO913403D0 publication Critical patent/NO913403D0/en
Publication of NO913403L publication Critical patent/NO913403L/en
Publication of NO180297B publication Critical patent/NO180297B/en
Publication of NO180297C publication Critical patent/NO180297C/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/04—X-ray contrast preparations
    • A61K49/0433—X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/28—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
    • C07C237/46—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having carbon atoms of carboxamide groups, amino groups and at least three atoms of bromine or iodine, bound to carbon atoms of the same non-condensed six-membered aromatic ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/04—X-ray contrast preparations

Abstract

Compounds having general formula (I), wherein R is selected among 2,3-dihydroxypropyl and 1,3-dihydroxy-2-propyl groups. These compounds can be used as contrasting products for X-ray image formation.
NO913403A 1990-01-05 1991-08-30 Nonionic iodinated compounds and contrast agents containing the same NO180297C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9000106A FR2656865B1 (en) 1990-01-05 1990-01-05 NON-IONIC IODINE COMPOUND, PROCESS FOR PREPARING THE SAME, AND CONTRAST PRODUCT CONTAINING THE SAME.
PCT/FR1990/000969 WO1991009836A1 (en) 1990-01-05 1990-12-28 Nonionic iodinated compounds, method for preparing them, and contrast products containing same

Publications (4)

Publication Number Publication Date
NO913403D0 NO913403D0 (en) 1991-08-30
NO913403L NO913403L (en) 1991-08-30
NO180297B NO180297B (en) 1996-12-16
NO180297C true NO180297C (en) 1997-03-26

Family

ID=9392557

Family Applications (1)

Application Number Title Priority Date Filing Date
NO913403A NO180297C (en) 1990-01-05 1991-08-30 Nonionic iodinated compounds and contrast agents containing the same

Country Status (25)

Country Link
EP (1) EP0437144B1 (en)
JP (1) JP2529032B2 (en)
KR (1) KR100194506B1 (en)
AT (1) ATE114639T1 (en)
CA (1) CA2050334C (en)
CZ (1) CZ283986B6 (en)
DE (1) DE69014581T2 (en)
DK (1) DK0437144T3 (en)
ES (1) ES2067710T3 (en)
FI (1) FI102746B1 (en)
FR (1) FR2656865B1 (en)
GR (1) GR3015183T3 (en)
HK (1) HK1006019A1 (en)
HU (1) HUT59079A (en)
IE (1) IE65329B1 (en)
IL (1) IL96812A (en)
NO (1) NO180297C (en)
NZ (1) NZ236675A (en)
PL (1) PL165683B1 (en)
PT (1) PT96410B (en)
RO (1) RO108559B1 (en)
SK (1) SK279646B6 (en)
TR (1) TR24944A (en)
WO (1) WO1991009836A1 (en)
ZA (1) ZA9173B (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2687669B1 (en) * 1992-02-24 1997-12-19 Guerbet Sa COMPOUNDS FOR USE IN CONTRAST PRODUCTS FOR RADIOGRAPHY.
IT1256163B (en) * 1992-10-27 1995-11-29 Zambon Spa PROCESS FOR THE PREPARATION OF AN INTERMEDIATE OF THE ORGANIC SYNTHESIS
IT1283319B1 (en) * 1996-03-29 1998-04-16 Zambon Spa PROCESS FOR THE PREPARATION OF A USEFUL INTERMEDIATE IN THE SYNTHESIS OF HYDURATED CONTRAST MEDIA
PT108524B (en) 2015-06-02 2017-12-15 Hovione Farmaciência S A PROCESS FOR THE PREPARATION OF USEFUL INTERMEDIARIES IN THE PREPARATION OF NON-IONIC CONTRACTING AGENTS
CN108947959B (en) * 2017-05-27 2022-09-20 正大天晴药业集团股份有限公司 Preparation method of non-ionic iodine contrast agent intermediate
CN110903275A (en) * 2018-09-14 2020-03-24 苏州科伦药物研究有限公司 Process for producing iobitridol, intermediate therefor, and process for producing the same

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2909439A1 (en) * 1979-03-08 1980-09-18 Schering Ag NEW NON-ionic x-ray contrast agents
DE3429949A1 (en) * 1984-08-10 1986-02-20 Schering AG, 1000 Berlin und 4709 Bergkamen Novel non-ionic 2,4,6-triiodoisophthalic acid bisamides, process for the preparation thereof and the use thereof as X-ray contrast media
IL90326A (en) * 1988-06-02 1993-05-13 Guerbet Sa Non-ionic triiodobenzene compounds and contrast media containing them

Also Published As

Publication number Publication date
FI914114A (en) 1992-06-29
JP2529032B2 (en) 1996-08-28
DE69014581D1 (en) 1995-01-12
KR100194506B1 (en) 1999-06-15
FI102746B (en) 1999-02-15
TR24944A (en) 1992-07-01
NZ236675A (en) 1992-08-26
JPH05132455A (en) 1993-05-28
FI914114A0 (en) 1991-09-02
FR2656865A1 (en) 1991-07-12
CA2050334A1 (en) 1991-07-06
AU7057491A (en) 1991-07-24
KR920701132A (en) 1992-08-11
ATE114639T1 (en) 1994-12-15
CZ283986B6 (en) 1998-07-15
AU641212B2 (en) 1993-09-16
IE910035A1 (en) 1991-07-17
ES2067710T3 (en) 1995-04-01
IL96812A0 (en) 1991-09-16
PL165683B1 (en) 1995-01-31
DE69014581T2 (en) 1995-06-08
IL96812A (en) 1995-05-26
EP0437144A1 (en) 1991-07-17
EP0437144B1 (en) 1994-11-30
IE65329B1 (en) 1995-10-18
ZA9173B (en) 1992-08-26
WO1991009836A1 (en) 1991-07-11
NO913403D0 (en) 1991-08-30
PT96410B (en) 1998-06-30
SK279646B6 (en) 1999-01-11
HK1006019A1 (en) 1999-02-05
RO108559B1 (en) 1994-06-30
FI102746B1 (en) 1999-02-15
FR2656865B1 (en) 1993-03-26
DK0437144T3 (en) 1995-01-23
PT96410A (en) 1991-10-15
PL288603A1 (en) 1992-04-06
CS648290A3 (en) 1992-02-19
NO180297B (en) 1996-12-16
HU912860D0 (en) 1992-02-28
GR3015183T3 (en) 1995-05-31
NO913403L (en) 1991-08-30
HUT59079A (en) 1992-04-28
CA2050334C (en) 1999-09-07

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Legal Events

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MK1K Patent expired