FI914114A - CONTAINERS OF IODINERADES, ICKE-IONISERADE FOERENINGAR, FOERFARANDE FOER DERAS FRAMSTAELLNING OCH DESSA INNEHAOLLANDE KONTRASTMELEL. - Google Patents

CONTAINERS OF IODINERADES, ICKE-IONISERADE FOERENINGAR, FOERFARANDE FOER DERAS FRAMSTAELLNING OCH DESSA INNEHAOLLANDE KONTRASTMELEL. Download PDF

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Publication number
FI914114A
FI914114A FI914114A FI914114A FI914114A FI 914114 A FI914114 A FI 914114A FI 914114 A FI914114 A FI 914114A FI 914114 A FI914114 A FI 914114A FI 914114 A FI914114 A FI 914114A
Authority
FI
Finland
Prior art keywords
kontrastmelel
ioniserade
iodinerades
foereningar
icke
Prior art date
Application number
FI914114A
Other languages
Finnish (fi)
Other versions
FI914114A0 (en
FI102746B (en
FI102746B1 (en
Inventor
Michel Schaefer
Maryse Dugast-Zrihen
Michael Guillemot
Didier Doucet
Dominigue Meyer
Original Assignee
Guerbet Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Guerbet Sa filed Critical Guerbet Sa
Publication of FI914114A0 publication Critical patent/FI914114A0/en
Publication of FI914114A publication Critical patent/FI914114A/en
Application granted granted Critical
Publication of FI102746B publication Critical patent/FI102746B/en
Publication of FI102746B1 publication Critical patent/FI102746B1/en

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/04X-ray contrast preparations
    • A61K49/0433X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/28Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
    • C07C237/46Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having carbon atoms of carboxamide groups, amino groups and at least three atoms of bromine or iodine, bound to carbon atoms of the same non-condensed six-membered aromatic ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/04X-ray contrast preparations

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Cephalosporin Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Compounds having general formula (I), wherein R is selected among 2,3-dihydroxypropyl and 1,3-dihydroxy-2-propyl groups. These compounds can be used as contrasting products for X-ray image formation.
FI914114A 1990-01-05 1991-09-02 Iodized, non-ionized compounds, processes for their preparation and those containing contrast agents FI102746B1 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
FR9000106A FR2656865B1 (en) 1990-01-05 1990-01-05 NON-IONIC IODINE COMPOUND, PROCESS FOR PREPARING THE SAME, AND CONTRAST PRODUCT CONTAINING THE SAME.
FR9000106 1990-01-05
FR9000969 1990-12-28
PCT/FR1990/000969 WO1991009836A1 (en) 1990-01-05 1990-12-28 Nonionic iodinated compounds, method for preparing them, and contrast products containing same

Publications (4)

Publication Number Publication Date
FI914114A0 FI914114A0 (en) 1991-09-02
FI914114A true FI914114A (en) 1992-06-29
FI102746B FI102746B (en) 1999-02-15
FI102746B1 FI102746B1 (en) 1999-02-15

Family

ID=9392557

Family Applications (1)

Application Number Title Priority Date Filing Date
FI914114A FI102746B1 (en) 1990-01-05 1991-09-02 Iodized, non-ionized compounds, processes for their preparation and those containing contrast agents

Country Status (25)

Country Link
EP (1) EP0437144B1 (en)
JP (1) JP2529032B2 (en)
KR (1) KR100194506B1 (en)
AT (1) ATE114639T1 (en)
CA (1) CA2050334C (en)
CZ (1) CZ283986B6 (en)
DE (1) DE69014581T2 (en)
DK (1) DK0437144T3 (en)
ES (1) ES2067710T3 (en)
FI (1) FI102746B1 (en)
FR (1) FR2656865B1 (en)
GR (1) GR3015183T3 (en)
HK (1) HK1006019A1 (en)
HU (1) HUT59079A (en)
IE (1) IE65329B1 (en)
IL (1) IL96812A (en)
NO (1) NO180297C (en)
NZ (1) NZ236675A (en)
PL (1) PL165683B1 (en)
PT (1) PT96410B (en)
RO (1) RO108559B1 (en)
SK (1) SK279646B6 (en)
TR (1) TR24944A (en)
WO (1) WO1991009836A1 (en)
ZA (1) ZA9173B (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2687669B1 (en) * 1992-02-24 1997-12-19 Guerbet Sa COMPOUNDS FOR USE IN CONTRAST PRODUCTS FOR RADIOGRAPHY.
IT1256163B (en) * 1992-10-27 1995-11-29 Zambon Spa PROCESS FOR THE PREPARATION OF AN INTERMEDIATE OF THE ORGANIC SYNTHESIS
IT1283319B1 (en) * 1996-03-29 1998-04-16 Zambon Spa PROCESS FOR THE PREPARATION OF A USEFUL INTERMEDIATE IN THE SYNTHESIS OF HYDURATED CONTRAST MEDIA
PT108524B (en) 2015-06-02 2017-12-15 Hovione Farmaciência S A PROCESS FOR THE PREPARATION OF USEFUL INTERMEDIARIES IN THE PREPARATION OF NON-IONIC CONTRACTING AGENTS
CN108947959B (en) * 2017-05-27 2022-09-20 正大天晴药业集团股份有限公司 Preparation method of non-ionic iodine contrast agent intermediate
CN110903275A (en) * 2018-09-14 2020-03-24 苏州科伦药物研究有限公司 Process for producing iobitridol, intermediate therefor, and process for producing the same

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2909439A1 (en) * 1979-03-08 1980-09-18 Schering Ag NEW NON-ionic x-ray contrast agents
DE3429949A1 (en) * 1984-08-10 1986-02-20 Schering AG, 1000 Berlin und 4709 Bergkamen Novel non-ionic 2,4,6-triiodoisophthalic acid bisamides, process for the preparation thereof and the use thereof as X-ray contrast media
IL90326A (en) * 1988-06-02 1993-05-13 Guerbet Sa Non-ionic triiodobenzene compounds and contrast media containing them

Also Published As

Publication number Publication date
DE69014581D1 (en) 1995-01-12
KR920701132A (en) 1992-08-11
NZ236675A (en) 1992-08-26
JPH05132455A (en) 1993-05-28
AU641212B2 (en) 1993-09-16
SK279646B6 (en) 1999-01-11
CA2050334C (en) 1999-09-07
FR2656865B1 (en) 1993-03-26
IL96812A (en) 1995-05-26
CA2050334A1 (en) 1991-07-06
EP0437144B1 (en) 1994-11-30
DK0437144T3 (en) 1995-01-23
HK1006019A1 (en) 1999-02-05
DE69014581T2 (en) 1995-06-08
ES2067710T3 (en) 1995-04-01
ZA9173B (en) 1992-08-26
KR100194506B1 (en) 1999-06-15
TR24944A (en) 1992-07-01
AU7057491A (en) 1991-07-24
PT96410B (en) 1998-06-30
NO180297B (en) 1996-12-16
EP0437144A1 (en) 1991-07-17
WO1991009836A1 (en) 1991-07-11
PL288603A1 (en) 1992-04-06
HUT59079A (en) 1992-04-28
NO180297C (en) 1997-03-26
NO913403L (en) 1991-08-30
RO108559B1 (en) 1994-06-30
NO913403D0 (en) 1991-08-30
ATE114639T1 (en) 1994-12-15
PT96410A (en) 1991-10-15
CZ283986B6 (en) 1998-07-15
FR2656865A1 (en) 1991-07-12
PL165683B1 (en) 1995-01-31
IE910035A1 (en) 1991-07-17
CS648290A3 (en) 1992-02-19
FI914114A0 (en) 1991-09-02
HU912860D0 (en) 1992-02-28
JP2529032B2 (en) 1996-08-28
IL96812A0 (en) 1991-09-16
GR3015183T3 (en) 1995-05-31
IE65329B1 (en) 1995-10-18
FI102746B (en) 1999-02-15
FI102746B1 (en) 1999-02-15

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