IT1256163B - PROCESS FOR THE PREPARATION OF AN INTERMEDIATE OF THE ORGANIC SYNTHESIS - Google Patents

PROCESS FOR THE PREPARATION OF AN INTERMEDIATE OF THE ORGANIC SYNTHESIS

Info

Publication number
IT1256163B
IT1256163B ITMI922451A ITMI922451A IT1256163B IT 1256163 B IT1256163 B IT 1256163B IT MI922451 A ITMI922451 A IT MI922451A IT MI922451 A ITMI922451 A IT MI922451A IT 1256163 B IT1256163 B IT 1256163B
Authority
IT
Italy
Prior art keywords
preparation
organic synthesis
triiode
propionylamino
acetoxy
Prior art date
Application number
ITMI922451A
Other languages
Italian (it)
Inventor
Marco Villa
Antonio Nardi
Fabio Benedetti
Original Assignee
Zambon Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zambon Spa filed Critical Zambon Spa
Priority to ITMI922451A priority Critical patent/IT1256163B/en
Publication of ITMI922451A0 publication Critical patent/ITMI922451A0/en
Priority to CH02991/93A priority patent/CH688147A5/en
Priority to GB9320888A priority patent/GB2272218B/en
Priority to NL9301822A priority patent/NL194271C/en
Priority to DE4336154A priority patent/DE4336154A1/en
Priority to FR9312614A priority patent/FR2697249B1/en
Priority to ES09302237A priority patent/ES2073370B1/en
Publication of ITMI922451A1 publication Critical patent/ITMI922451A1/en
Application granted granted Critical
Publication of IT1256163B publication Critical patent/IT1256163B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/02—Preparation of carboxylic acid amides from carboxylic acids or from esters, anhydrides, or halides thereof by reaction with ammonia or amines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Viene descritto un miglioramento ad un processo per la preparazione della bis-(1,3-diidrossipropilammide) dell'acido L-5-(2-acetossi-propionilammino)-2,4,6-triiodo-isoftalico per reazione tra dicloruro dell'acido L-5-(2-acetossi-propionilammino)-2,4,6-triiodo-isoftalico e 2-ammino-1,3-propandiolo in presenza di una base.An improvement to a process for the preparation of the bis- (1,3-dihydroxypropylamide) of the L-5- (2-acetoxy-propionylamino) -2,4,6-triiode-isophthalic acid by reaction between dichloride of the L-5- (2-acetoxy-propionylamino) -2,4,6-triiode-isophthalic acid and 2-amino-1,3-propanediol in the presence of a base.

ITMI922451A 1992-10-27 1992-10-27 PROCESS FOR THE PREPARATION OF AN INTERMEDIATE OF THE ORGANIC SYNTHESIS IT1256163B (en)

Priority Applications (7)

Application Number Priority Date Filing Date Title
ITMI922451A IT1256163B (en) 1992-10-27 1992-10-27 PROCESS FOR THE PREPARATION OF AN INTERMEDIATE OF THE ORGANIC SYNTHESIS
CH02991/93A CH688147A5 (en) 1992-10-27 1993-10-05 Process for the preparation of the compound bis- (1,3-diidrossipropilamide) of L-5- (2-acetoxy-propionylamino) -2,4,6-triiodo-isophthalic.
GB9320888A GB2272218B (en) 1992-10-27 1993-10-11 Process for the preparation of 2,4,6-triiodo-isophthalic acid bis-(1,3-dihydroxypropylamide) derivatives
NL9301822A NL194271C (en) 1992-10-27 1993-10-20 Process for the preparation of the compound L-5- (2-acetoxy-propionylamino) -2,4,6-triiodoisophthalic acid bis- (1,3-dihydropropylamide).
DE4336154A DE4336154A1 (en) 1992-10-27 1993-10-22 Process for the preparation of L-5- (2-acetoxypropionylamino) -2,4,6-triiodo-isophthalic acid-bis-1,3-dihydroxy-polyamide)
FR9312614A FR2697249B1 (en) 1992-10-27 1993-10-22 Process for the preparation of bis (1,3-dihydroxypropylamide) of L-5- (2-acetoxypropionylamino) -2,4,6-triiodoisophthalic acid.
ES09302237A ES2073370B1 (en) 1992-10-27 1993-10-26 PROCEDURE FOR THE PREPARATION OF THE COMPOUND BIS- (1,3-DIHIDROXI-PROPILAMIDA) OF THE ACID L-5- (2-ACETOXI-PROPIONILAMINO) -2,4,6-TRIYODO-ISOFTALICO.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITMI922451A IT1256163B (en) 1992-10-27 1992-10-27 PROCESS FOR THE PREPARATION OF AN INTERMEDIATE OF THE ORGANIC SYNTHESIS

Publications (3)

Publication Number Publication Date
ITMI922451A0 ITMI922451A0 (en) 1992-10-27
ITMI922451A1 ITMI922451A1 (en) 1994-04-27
IT1256163B true IT1256163B (en) 1995-11-29

Family

ID=11364170

Family Applications (1)

Application Number Title Priority Date Filing Date
ITMI922451A IT1256163B (en) 1992-10-27 1992-10-27 PROCESS FOR THE PREPARATION OF AN INTERMEDIATE OF THE ORGANIC SYNTHESIS

Country Status (7)

Country Link
CH (1) CH688147A5 (en)
DE (1) DE4336154A1 (en)
ES (1) ES2073370B1 (en)
FR (1) FR2697249B1 (en)
GB (1) GB2272218B (en)
IT (1) IT1256163B (en)
NL (1) NL194271C (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1283319B1 (en) * 1996-03-29 1998-04-16 Zambon Spa PROCESS FOR THE PREPARATION OF A USEFUL INTERMEDIATE IN THE SYNTHESIS OF HYDURATED CONTRAST MEDIA
US6262303B1 (en) 1998-05-08 2001-07-17 Dibra S.P.A. Process for the preparation of S-N,N′-bis[2-hydroxy-1-(hydroxymethyl)ethyl]-5-[(2-hydroxy-1-oxopropyl)-amino]-2,4,6-triiodo-1,3-benzenedicarboxamide
IT1299202B1 (en) * 1998-05-08 2000-02-29 Dibra Spa PROCESS FOR THE PREPARATION OF S-N, N'-BIS (2-HYDROXY-1- (HYDROXIMETHYL) ETHYL) -5 - ((2-HYDROXY-1-OXOPROPYL) AMINO) -2,4,6-TRIIODE
IT1302200B1 (en) 1998-09-11 2000-07-31 Dibra Spa PROCESS FOR THE PREPARATION OF THE S-N, N'-BIS ° 2-IDROSSI-1- (IDROSSIMETIL) ETILé-5- ° (2-IDROSSI-1-
US6803485B2 (en) 1999-02-26 2004-10-12 Bracco Imaging S.P.A. Process for the preparation of iopamidol

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH608189A5 (en) * 1974-12-13 1978-12-29 Savac Ag
FR2656865B1 (en) * 1990-01-05 1993-03-26 Guerbet Sa NON-IONIC IODINE COMPOUND, PROCESS FOR PREPARING THE SAME, AND CONTRAST PRODUCT CONTAINING THE SAME.
ES2017277A6 (en) * 1989-09-20 1991-01-16 Juste Sa Process for the preparation of new non-ionic iodated contrast media

Also Published As

Publication number Publication date
ES2073370B1 (en) 1996-02-16
DE4336154A1 (en) 1994-04-28
GB9320888D0 (en) 1993-12-01
GB2272218B (en) 1995-11-22
NL9301822A (en) 1994-05-16
ES2073370A1 (en) 1995-08-01
FR2697249A1 (en) 1994-04-29
GB2272218A (en) 1994-05-11
ITMI922451A0 (en) 1992-10-27
ITMI922451A1 (en) 1994-04-27
CH688147A5 (en) 1997-05-30
NL194271B (en) 2001-07-02
FR2697249B1 (en) 1995-04-14
NL194271C (en) 2001-11-05

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Legal Events

Date Code Title Description
0001 Granted
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19971029