NO175620C - Fremgangsmåte for fremstilling av et antitumorvirksomt legemiddel - Google Patents

Fremgangsmåte for fremstilling av et antitumorvirksomt legemiddel

Info

Publication number
NO175620C
NO175620C NO873244A NO873244A NO175620C NO 175620 C NO175620 C NO 175620C NO 873244 A NO873244 A NO 873244A NO 873244 A NO873244 A NO 873244A NO 175620 C NO175620 C NO 175620C
Authority
NO
Norway
Prior art keywords
pct
preparation
antitumor drug
sec
date
Prior art date
Application number
NO873244A
Other languages
English (en)
Norwegian (no)
Other versions
NO175620B (fr
NO873244L (no
NO873244D0 (no
Inventor
Hansjoerg Eibl
Original Assignee
Max Planck Gesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Max Planck Gesellschaft filed Critical Max Planck Gesellschaft
Publication of NO873244D0 publication Critical patent/NO873244D0/no
Publication of NO873244L publication Critical patent/NO873244L/no
Publication of NO175620B publication Critical patent/NO175620B/no
Publication of NO175620C publication Critical patent/NO175620C/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
    • A61K31/685—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/075—Ethers or acetals
    • A61K31/08—Ethers or acetals acyclic, e.g. paraformaldehyde
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/22—Amides of acids of phosphorus
    • C07F9/24—Esteramides
    • C07F9/2454—Esteramides the amide moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/2458—Esteramides the amide moiety containing a substituent or a structure which is considered as characteristic of aliphatic amines

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Respiratory Apparatuses And Protective Means (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Adhesives Or Adhesive Processes (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
  • Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)
  • Electrically Operated Instructional Devices (AREA)
  • Medicinal Preparation (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Steroid Compounds (AREA)
NO873244A 1985-12-04 1987-08-03 Fremgangsmåte for fremstilling av et antitumorvirksomt legemiddel NO175620C (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE3542893 1985-12-04
DE3606631 1986-02-28
PCT/EP1986/000706 WO1987003478A2 (fr) 1985-12-04 1986-12-04 Medicaments

Publications (4)

Publication Number Publication Date
NO873244D0 NO873244D0 (no) 1987-08-03
NO873244L NO873244L (no) 1987-10-01
NO175620B NO175620B (fr) 1994-08-01
NO175620C true NO175620C (no) 1994-11-09

Family

ID=25838509

Family Applications (2)

Application Number Title Priority Date Filing Date
NO873243A NO174877C (no) 1985-12-04 1987-08-03 Fremgangsmåte for fremstilling av et legemiddel med antitumorvirkning
NO873244A NO175620C (no) 1985-12-04 1987-08-03 Fremgangsmåte for fremstilling av et antitumorvirksomt legemiddel

Family Applications Before (1)

Application Number Title Priority Date Filing Date
NO873243A NO174877C (no) 1985-12-04 1987-08-03 Fremgangsmåte for fremstilling av et legemiddel med antitumorvirkning

Country Status (15)

Country Link
US (2) US4837023A (fr)
EP (4) EP0230575A3 (fr)
JP (2) JPH0637393B2 (fr)
AT (2) ATE75608T1 (fr)
CA (2) CA1338627C (fr)
DE (4) DE3641491A1 (fr)
DK (2) DK172954B1 (fr)
ES (2) ES2032755T3 (fr)
FI (2) FI873363A (fr)
GR (2) GR3002487T3 (fr)
HU (2) HU203201B (fr)
IE (2) IE59777B1 (fr)
NO (2) NO174877C (fr)
PT (2) PT83872B (fr)
WO (2) WO1987003478A2 (fr)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5916884A (en) * 1985-12-04 1999-06-29 Max-Planck-Gesellschaft Zur Foederung Der Wissenschaften Compositions containing a mixture of phosphorus compounds and alkylglycerols
CA2001401A1 (fr) * 1988-10-25 1990-04-25 Claude Piantadosi Derives d'ether ou d'ester lipidique contenant une amine quaternaire et composes therapeutiques
US5182271A (en) * 1989-08-10 1993-01-26 Sandoz Ltd. Thioether, keto-ester and alkyl phospholipids useful in treating multiple sclerosis
DE69026991T2 (de) * 1989-08-10 1997-01-16 Sandoz Ag Phospholipide zur Behandlung der multiplen Sklerose
US5290769A (en) * 1989-09-27 1994-03-01 Asta Pharma Aktiengesellschaft Use of hexadecylphosphocholine for the treatment of psoriasis
EP0916343A1 (fr) * 1989-09-27 1999-05-19 ASTA Medica Aktiengesellschaft utilisation de composés alkyl phosphoriques dans le traitement de maladies psoriatiques
DE4111105A1 (de) * 1991-04-05 1992-10-08 Max Planck Gesellschaft Neue erucyl-, brassidyl- und nervonylderivate
US5369097A (en) * 1991-04-25 1994-11-29 The University Of British Columbia Phosphonates as anti-cancer agents
US5506217A (en) * 1991-04-25 1996-04-09 The University Of British Columbia Phosphonates as anti-cancer agents
ATE158295T1 (de) * 1991-07-04 1997-10-15 Asta Medica Ag Verfahren zur herstellung von alkylphosphocholinen und reinherstellung derselben
US6254879B1 (en) 1991-09-27 2001-07-03 Max-Planck-Gessellschaft zun Förderung der Wissenschaften e.V. Methods of treating protozoal diseases
US5298655A (en) * 1991-09-27 1994-03-29 Merck & Co., Inc. Farnesyl pyrophosphate analogs
DE4132344A1 (de) * 1991-09-27 1993-04-01 Max Planck Gesellschaft Verfahren zur herstellung eines arzneimittels zur oralen oder topischen verabreichung bei der behandlung von leishmaniasis
US6172050B1 (en) 1992-07-11 2001-01-09 Asta Medica Aktiengesellschaft Phospholipid derivatives
DE4222910A1 (de) * 1992-07-11 1994-01-13 Asta Medica Ag Neue Phospholipidderivate
DE4235911A1 (de) * 1992-10-23 1994-04-28 Asta Medica Ag Stabilisierte Hexadecylphosphocholinlösungen in Glycerinalkylethern
EP0702556B1 (fr) * 1993-06-10 2002-10-23 Wake Forest University (phospho)lipides contre l'infection a virus de l'hepatite b
US6551623B1 (en) 1993-09-09 2003-04-22 Lorus Therapeutics Inc. Immunomodulating compositions from bile
ATE244570T1 (de) 1993-09-09 2003-07-15 Lorus Therapeutics Inc Immunmodulierende zusammensetzungen aus galle
AU3216695A (en) * 1994-08-29 1996-03-22 University Of North Carolina At Chapel Hill, The Lipid analogs for treating viral infections
US7135584B2 (en) * 1995-08-07 2006-11-14 Wake Forest University Lipid analogs for treating viral infections
US5574025A (en) * 1994-10-26 1996-11-12 Merck & Co., Inc. Inhibitors of prenyl-protein transferases
AU1573495A (en) * 1995-02-10 1996-08-27 University Of British Columbia, The {4-hexadecyl-3-methoxy-butyl} phosphonic acid and its protienconjugates useful as anti-cancer agents
CA2215339C (fr) 1995-03-16 1999-01-19 Imutec Pharma Inc. Compositions immunomodulatrices d'origine biliaire destinees au traitement de troubles du systeme immunitaire
KR100499190B1 (ko) * 1996-03-29 2006-04-17 교와 핫꼬 고교 가부시끼가이샤 육모제
US20040101569A1 (en) * 1996-05-16 2004-05-27 Lorus Therapeutics Inc. Immunomodulating compositions from bile
US6121245A (en) * 1997-01-29 2000-09-19 Firshein; Richard N. Method of treating cancer using alkylglycerols in conjunction with chemotherapy
SE9701912D0 (sv) * 1997-05-22 1997-05-22 Interhealth Ab Pharmaceutical composition and use thereof
US7582678B2 (en) * 1997-07-09 2009-09-01 D-Pharm Limited Use of branched-chain fatty acids and derivatives thereof for the treatment of pain
PT1051159E (pt) * 1998-01-22 2002-09-30 Zentaris Ag Composicoes farmaceuticas solidas contendo miltefosina para administracao oral no tratamento de leishmaniose
US7026469B2 (en) * 2000-10-19 2006-04-11 Wake Forest University School Of Medicine Compositions and methods of double-targeting virus infections and cancer cells
IL137672A0 (en) 2000-08-03 2001-10-31 Dpharm Ltd Derivatives of branched-chain lipophilic molecules and uses thereof
US7309696B2 (en) 2000-10-19 2007-12-18 Wake Forest University Compositions and methods for targeting cancer cells
WO2002096826A2 (fr) * 2001-05-29 2002-12-05 Koninklijke Philips Electronics N.V. Liaison metal-ceramique
KR100871648B1 (ko) * 2001-08-31 2008-12-03 톰슨 라이센싱 조건부 액세스 시스템을 구현하는 방법, 컨텐트를 전송하는 방법 및 그 장치 및 컨텐트를 수신하고 처리하는 방법 및 그 장치
WO2003090757A1 (fr) * 2002-04-26 2003-11-06 Rudolf Perl Compositions pharmaceutiques de derives phospholipidiques
US20050187191A1 (en) * 2004-02-20 2005-08-25 Kucera Louis S. Methods and compositions for the treatment of respiratory syncytial virus
JP5232009B2 (ja) 2005-12-19 2013-07-10 エテルナ ツェンタリス ゲゼルシャフト ミット ベシュレンクテル ハフツング 低減された細胞毒性を有するアルキルリン脂質誘導体並びにそれらの使用
WO2008074573A1 (fr) * 2006-12-20 2008-06-26 Alphaptose Gmbh Forme posologique topique comprenant des composés de glycérol trisubstitué
JP2011057647A (ja) * 2009-09-14 2011-03-24 Adeka Corp 化粧料
ES2759584T3 (es) 2011-06-24 2020-05-11 Gri Bio Inc Prevención y tratamiento de afecciones inflamatorias
CN102491994B (zh) * 2011-12-07 2014-10-15 宁波九胜创新医药科技有限公司 一种胆碱磷酸烷基酯的制备方法
RU2749132C2 (ru) * 2014-12-09 2021-06-04 Гри Био, Инк. Предотвращение и лечение воспалительных состояний

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3225227A1 (de) * 1982-07-06 1984-01-12 Max Planck Gesellschaft zur Förderung der Wissenschaften e.V., 3400 Göttingen Derivate des n.n-bis-(2-chlor-aethyl)-phosphorsaeureamids
JPS5984824A (ja) * 1982-11-08 1984-05-16 Takeda Chem Ind Ltd 抗腫瘍剤
US4690935A (en) * 1983-03-31 1987-09-01 Wayne State University Inhibition of tumor growth and metastasis with calcium channel blocker compounds

Also Published As

Publication number Publication date
JP2857084B2 (ja) 1999-02-10
WO1987003480A2 (fr) 1987-06-18
EP0225608A3 (fr) 1987-10-28
FI873364A (fi) 1987-08-03
JPH0859677A (ja) 1996-03-05
EP0248047A1 (fr) 1987-12-09
NO175620B (fr) 1994-08-01
WO1987003478A2 (fr) 1987-06-18
NO873244L (no) 1987-10-01
DK398587A (da) 1987-07-30
DE3641379A1 (de) 1987-09-03
ES2032755T3 (es) 1993-03-01
DE19375061I2 (de) 2008-11-20
GR3005168T3 (fr) 1993-05-24
DE3641491A1 (de) 1987-09-17
EP0230575A3 (fr) 1987-12-02
IE863176L (en) 1987-06-04
WO1987003480A3 (fr) 1988-02-25
PT83873A (de) 1987-01-01
FI873364A0 (fi) 1987-08-03
ATE75608T1 (de) 1992-05-15
EP0225608A2 (fr) 1987-06-16
JPS63501719A (ja) 1988-07-14
NO174877C (no) 1994-07-27
NO873243D0 (no) 1987-08-03
NO873244D0 (no) 1987-08-03
NO174877B (no) 1994-04-18
HUT44441A (en) 1988-03-28
EP0248062A1 (fr) 1987-12-09
DE3679908D1 (de) 1991-07-25
JPH0637393B2 (ja) 1994-05-18
WO1987003478A3 (fr) 1987-09-24
HU208143B (en) 1993-08-30
FI873363A0 (fi) 1987-08-03
US4837023A (en) 1989-06-06
CA1338627C (fr) 1996-10-01
ATE64529T1 (de) 1991-07-15
IE59778B1 (en) 1994-04-06
PT83873B (pt) 1989-01-17
GR3002487T3 (en) 1992-12-30
DK172954B1 (da) 1999-10-18
NO873243L (no) 1987-10-02
EP0248062B1 (fr) 1992-05-06
EP0248047B1 (fr) 1991-06-19
US5049552A (en) 1991-09-17
PT83872A (de) 1987-01-01
HU203201B (en) 1991-06-28
CA1280369C (fr) 1991-02-19
HUT44431A (en) 1988-03-28
PT83872B (pt) 1989-01-17
IE59777B1 (en) 1994-04-06
EP0230575A2 (fr) 1987-08-05
FI873363A (fi) 1987-08-03
DK398587D0 (da) 1987-07-30
ES2038215T3 (es) 1993-07-16
IE863177L (en) 1987-06-04
DK393187D0 (da) 1987-07-28
DK393187A (da) 1987-07-28

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Legal Events

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MM1K Lapsed by not paying the annual fees