NO175132C - Fremgangsmåte ved fremstilling av legemiddel inneholdende Dipyridamol eller Mopidamol og 0-acetylsalisyre samt deres fysiologisk fordragelige salter - Google Patents

Fremgangsmåte ved fremstilling av legemiddel inneholdende Dipyridamol eller Mopidamol og 0-acetylsalisyre samt deres fysiologisk fordragelige salter

Info

Publication number
NO175132C
NO175132C NO873370A NO873370A NO175132C NO 175132 C NO175132 C NO 175132C NO 873370 A NO873370 A NO 873370A NO 873370 A NO873370 A NO 873370A NO 175132 C NO175132 C NO 175132C
Authority
NO
Norway
Prior art keywords
mopidamol
acetylsalicylic acid
dipyridamol
preparation
physiologically tolerable
Prior art date
Application number
NO873370A
Other languages
English (en)
Norwegian (no)
Other versions
NO175132B (no
NO873370D0 (no
NO873370L (no
Inventor
Wolfgang Eisert
Peter Gruber
Original Assignee
Thomae Gmbh Dr K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=6307286&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO175132(C) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K
Publication of NO873370D0 publication Critical patent/NO873370D0/no
Publication of NO873370L publication Critical patent/NO873370L/no
Publication of NO175132B publication Critical patent/NO175132B/no
Publication of NO175132C publication Critical patent/NO175132C/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50—Pyridazines; Hydrogenated pyridazines
    • A61K31/5025—Pyridazines; Hydrogenated pyridazines ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5084—Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/60—Salicylic acid; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Production Of Liquid Hydrocarbon Mixture For Refining Petroleum (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
NO873370A 1986-08-13 1987-08-12 Fremgangsmåte ved fremstilling av legemiddel inneholdende Dipyridamol eller Mopidamol og 0-acetylsalisyre samt deres fysiologisk fordragelige salter NO175132C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19863627423 DE3627423A1 (de) 1986-08-13 1986-08-13 Arzneimittel enthaltend dipyridamol oder mopidamol und o-acetylsalicylsaeure bzw. deren physiologisch vertraegliche salze, verfahren zu ihrer herstellung und ihre verwendung zur bekaempfung der thrombusbildung

Publications (4)

Publication Number Publication Date
NO873370D0 NO873370D0 (no) 1987-08-12
NO873370L NO873370L (no) 1988-02-15
NO175132B NO175132B (no) 1994-05-30
NO175132C true NO175132C (no) 1994-09-07

Family

ID=6307286

Family Applications (2)

Application Number Title Priority Date Filing Date
NO873370A NO175132C (no) 1986-08-13 1987-08-12 Fremgangsmåte ved fremstilling av legemiddel inneholdende Dipyridamol eller Mopidamol og 0-acetylsalisyre samt deres fysiologisk fordragelige salter
NO1999014C NO1999014I1 (no) 1986-08-13 1999-07-01 Dipyridamol og acetylsalisylsyre

Family Applications After (1)

Application Number Title Priority Date Filing Date
NO1999014C NO1999014I1 (no) 1986-08-13 1999-07-01 Dipyridamol og acetylsalisylsyre

Country Status (26)

Country Link
US (1) US6015577A (da)
EP (1) EP0257344B1 (da)
JP (1) JP2593879B2 (da)
KR (1) KR950009098B1 (da)
AT (1) ATE59961T1 (da)
AU (1) AU603146B2 (da)
BR (1) BR1100593A (da)
CA (1) CA1302272C (da)
CL (1) CL2004001252A1 (da)
DD (1) DD263918A5 (da)
DE (3) DE3627423A1 (da)
DK (1) DK172236B1 (da)
ES (1) ES2020974B3 (da)
FI (1) FI873492A (da)
GR (1) GR3001695T3 (da)
HK (1) HK14494A (da)
HU (1) HU202404B (da)
IE (1) IE60862B1 (da)
IL (1) IL83510A (da)
NL (1) NL990001I2 (da)
NO (2) NO175132C (da)
NZ (1) NZ221424A (da)
PH (1) PH27176A (da)
PT (1) PT85525B (da)
SG (1) SG122593G (da)
ZA (1) ZA875947B (da)

Families Citing this family (34)

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DE19927689A1 (de) * 1999-06-17 2000-12-21 Gruenenthal Gmbh Orale Darreichungsformen zur Verabreichung einer fixen Kombination von Tramadol und Diclofenac
EP1093814A1 (en) * 1999-10-22 2001-04-25 Boehringer Ingelheim Pharma KG Use of dipyridamole or mopidamol in the manufacture of a medicament for the treatment and prevention of fibrin-dependent microcirculation disorders
US7064130B2 (en) * 2001-04-20 2006-06-20 Boehringer Ingelheim Pharma Gmbh & Co. Kg Use of radical-scavenging compounds for treatment and prevention of NO-dependent microcirculation disorders
US20040058056A1 (en) * 2001-07-06 2004-03-25 Shigemasa Osaki Drug diffusion coatings, applications and methods
US7253155B2 (en) * 2001-10-05 2007-08-07 Combinatorx, Inc. Combinations for the treatment of immunoinflammatory disorders
TW200301135A (en) * 2001-12-27 2003-07-01 Otsuka Maryland Res Inst Inc Pharmaceutical compositions comprising a multifunctional phosphodiesterase inhibitor and an adenosine uptake inhibitor
US20030181488A1 (en) * 2002-03-07 2003-09-25 Boehringer Ingelheim Pharma Gmbh & Co. Kg Administration form for the oral application of 3-[(2-{[4-(hexyloxycarbonylamino-imino-methyl)-phenylamino]-methyl}-1-methyl-1H-benzimidazol-5-carbonyl)-pyridin-2-yl-amino]-propionic acid ethyl ester and the salts thereof
DE10209982A1 (de) * 2002-03-07 2003-09-25 Boehringer Ingelheim Pharma Oral zu applizierende Darreichungsform für schwerlösliche basische Wirkstoffe
US7485322B2 (en) * 2002-12-24 2009-02-03 Lek Pharmaceuticals D.D. Modified release pharmaceutical composition
WO2004069254A2 (en) * 2003-02-07 2004-08-19 Boehringer Ingelheim International Gmbh Use of dipyridamole or mopidamole for treatment and prevention of mmp-9-dependent disorders
DE10306179A1 (de) 2003-02-13 2004-08-26 Boehringer Ingelheim Pharma Gmbh & Co. Kg Verwendung von Dipyridamol in Kombination mit Acetylsalicylsäure und einem Angiotensin II-Antagonisten zur Schlaganfall-Prophylaxe
EP1622621A2 (en) * 2003-04-24 2006-02-08 Boehringer Ingelheim International GmbH Use of dipyridamole or mopidamole for treatment and prevention of thrombo-embolic diseases and disorders caused by excessive formation of thrombin and/or by elevated expression of thrombin receptors
US7041286B2 (en) * 2003-07-23 2006-05-09 Nerenberg Arnold P Composition for mitigating a pernicious thrombotic event
TW200517114A (en) * 2003-10-15 2005-06-01 Combinatorx Inc Methods and reagents for the treatment of immunoinflammatory disorders
KR20070026577A (ko) * 2004-05-13 2007-03-08 베링거 인겔하임 인터내셔날 게엠베하 혈소판 억제제 저항성 치료를 위한 디피리다몰의 용도
AU2006226293B2 (en) 2005-03-22 2011-04-07 Losan Pharma Gmbh Solubilized ibuprofen
US20090214645A1 (en) * 2005-08-22 2009-08-27 Andrea Kramer Pharmaceutical compositions comprising a ph-dependent drug, a ph modifier and a retarding agent
KR20140088230A (ko) * 2006-01-27 2014-07-09 앱탈리스 파마테크, 인코포레이티드 약 염기성 약물과 유기산을 포함하는 약물 전달 시스템
US20070190145A1 (en) * 2006-01-27 2007-08-16 Eurand, Inc. Drug delivery systems comprising weakly basic selective serotonin 5-ht3 blocking agent and organic acids
EP1820506B1 (en) * 2006-02-09 2008-03-26 Teva Pharmaceutical Industries Ltd. Dipyridamole extended-release formulations and process for preparing same
US20080003213A1 (en) * 2006-05-22 2008-01-03 Jan Lessem Methods and compositions for the treatment of diseases or conditions associated with increased C-reactive protein, interleukin-6, or interferon-gamma levels
ITRM20060460A1 (it) * 2006-08-31 2006-11-30 Univ Roma Uso di acido acetil salicilico in combinazione con inibitori dei canali mrp4 per il trattamento di pazienti resistenti a detto acido acetil salicilico
EP2120878B1 (en) * 2007-02-09 2014-07-30 Alphapharm PTY LTD A dosage form containing two active pharmaceutical ingredients in different physical forms
US20090075955A1 (en) * 2007-09-19 2009-03-19 Combinatorx, Inc. Therapeutic regimens for the treatment of immunoinflammatory disorders
NZ586332A (en) * 2007-12-17 2012-07-27 Zalicus Inc Therapeutic regimens for the treatment of immunoinflammatory disorders using dipyridamole and prednisolone
WO2009097156A1 (en) * 2008-02-01 2009-08-06 Barr Laboratories, Inc. Pharmaceutical capsules comprising extended release dipyridamole pellets
US8133506B2 (en) * 2008-03-12 2012-03-13 Aptalis Pharmatech, Inc. Drug delivery systems comprising weakly basic drugs and organic acids
CA2716642C (en) * 2008-03-28 2017-02-28 Boehringer Ingelheim International Gmbh Method for manufacturing acid pellets
WO2010036975A2 (en) * 2008-09-25 2010-04-01 Teva Pharmaceutical Industries Ltd. Dipyridamole and acetylsalicylic acid formulations and process for preparing same
US20110003005A1 (en) * 2009-07-06 2011-01-06 Gopi Venkatesh Methods of Treating PDNV and PONV with Extended Release Ondansetron Compositions
EP2361615A1 (en) 2010-02-19 2011-08-31 Alfred E. Tiefenbacher GmbH & Co. KG Dipyridamole prolonged-release tablet
US20120301541A1 (en) * 2011-05-24 2012-11-29 Haronsky Elina Compressed core for pharmaceutical composition
CN103239724A (zh) * 2013-05-27 2013-08-14 成都自豪药业有限公司 抗血栓形成的联合用药物及其药物组合物
US11771659B2 (en) * 2017-06-19 2023-10-03 The Cleveland Clinic Foundation Treating disease and promoting weight loss by inhibiting the TMA/FMO3/TMAO pathway

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2368280A1 (fr) * 1976-10-20 1978-05-19 Theramex Nouvelle composition therapeutique presentant une activite anti-agregante plaquettaire, et son procede de preparation
FR2368272A1 (fr) * 1976-10-20 1978-05-19 Theramex Compositions therapeutiques solides pour combattre l'agregation plaquettaire
LU77353A1 (da) * 1977-05-16 1979-01-19
DE3000979A1 (de) * 1980-01-12 1981-07-23 Dr. Karl Thomae Gmbh, 7950 Biberach Neue dipyridamol-retardformen und verfahren zu ihrer herstellung
FR2513118A1 (fr) * 1981-09-18 1983-03-25 Rocador Sa Composition pharmaceutique a base de dipyridamol et de sel d'aluminium de l'acide acetylsalicylique pour combattre l'agregation plaquettaire
ATE50497T1 (de) * 1984-07-21 1990-03-15 Hoechst Ag Kombinationspraeparat aus pyrimido-pyrimidinen und o-acetylsalicylsaeure bzw. deren pharmakologisch vertraeglichen salzen und dessen verwendung.

Also Published As

Publication number Publication date
AU7679587A (en) 1988-02-18
BR1100593A (pt) 2002-04-02
IL83510A0 (en) 1988-01-31
NO1999014I1 (no) 1999-07-01
CA1302272C (en) 1992-06-02
DE3627423A1 (de) 1988-02-18
EP0257344A1 (de) 1988-03-02
HU202404B (en) 1991-03-28
CL2004001252A1 (es) 2005-03-04
PT85525B (pt) 1990-06-29
DD263918A5 (de) 1989-01-18
DE10299015I1 (de) 2002-10-10
FI873492A0 (fi) 1987-08-12
PH27176A (en) 1993-04-02
US6015577A (en) 2000-01-18
PT85525A (de) 1987-09-01
DK421187D0 (da) 1987-08-12
NL990001I2 (nl) 2000-04-03
DE3767408D1 (de) 1991-02-21
KR880002529A (ko) 1988-05-09
FI873492A (fi) 1988-02-14
ATE59961T1 (de) 1991-02-15
JPS6348219A (ja) 1988-02-29
SG122593G (en) 1994-06-10
NL990001I1 (nl) 1999-03-01
AU603146B2 (en) 1990-11-08
EP0257344B1 (de) 1991-01-16
GR3001695T3 (en) 1992-11-23
ZA875947B (en) 1989-04-26
NO175132B (no) 1994-05-30
DE10299015I2 (de) 2005-06-16
DK421187A (da) 1988-02-14
HUT44937A (en) 1988-05-30
IE872152L (en) 1988-02-13
KR950009098B1 (en) 1995-08-14
HK14494A (en) 1994-03-04
NZ221424A (en) 1989-11-28
ES2020974B3 (es) 1991-10-16
NO873370D0 (no) 1987-08-12
IL83510A (en) 1992-02-16
DK172236B1 (da) 1998-02-02
JP2593879B2 (ja) 1997-03-26
NO873370L (no) 1988-02-15
IE60862B1 (en) 1994-08-24

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