NO170013C - Analogifremgangsmaate for fremstilling av terapeutisk aktive di-t-butylfenoler substituert med alkoxy- eller benzyloxygruppe eller en benzylthiogrupp - Google Patents
Analogifremgangsmaate for fremstilling av terapeutisk aktive di-t-butylfenoler substituert med alkoxy- eller benzyloxygruppe eller en benzylthiogruppInfo
- Publication number
- NO170013C NO170013C NO884770A NO884770A NO170013C NO 170013 C NO170013 C NO 170013C NO 884770 A NO884770 A NO 884770A NO 884770 A NO884770 A NO 884770A NO 170013 C NO170013 C NO 170013C
- Authority
- NO
- Norway
- Prior art keywords
- thiography
- alcoxy
- benzyl
- preparation
- benzyloxy group
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
- C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D257/04—Five-membered rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
- C07C255/01—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms
- C07C255/16—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms containing cyano groups and singly-bound oxygen atoms bound to the same carbon atom of an acyclic carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C321/00—Thiols, sulfides, hydropolysulfides or polysulfides
- C07C321/24—Thiols, sulfides, hydropolysulfides, or polysulfides having thio groups bound to carbon atoms of six-membered aromatic rings
- C07C321/28—Sulfides, hydropolysulfides, or polysulfides having thio groups bound to carbon atoms of six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
- C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
- C07C59/66—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings
- C07C59/68—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings the oxygen atom of the ether group being bound to a non-condensed six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C65/21—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing ether groups, groups, groups, or groups
- C07C65/24—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing ether groups, groups, groups, or groups polycyclic
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S424/00—Drug, bio-affecting and body treating compositions
- Y10S424/81—Drug, bio-affecting and body treating compositions involving autoimmunity, allergy, immediate hypersensitivity, delayed hypersensitivity, immunosuppression, immunotolerance, or anergy
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US12046887A | 1987-11-13 | 1987-11-13 |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| NO884770D0 NO884770D0 (no) | 1988-10-26 |
| NO884770L NO884770L (no) | 1989-05-16 |
| NO170013B NO170013B (no) | 1992-05-25 |
| NO170013C true NO170013C (no) | 1992-09-02 |
Family
ID=22390487
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO884770A NO170013C (no) | 1987-11-13 | 1988-10-26 | Analogifremgangsmaate for fremstilling av terapeutisk aktive di-t-butylfenoler substituert med alkoxy- eller benzyloxygruppe eller en benzylthiogrupp |
Country Status (12)
| Country | Link |
|---|---|
| EP (1) | EP0317165B1 (da) |
| JP (1) | JP2520161B2 (da) |
| KR (1) | KR890008087A (da) |
| AU (1) | AU618764B2 (da) |
| CA (1) | CA1325431C (da) |
| DE (1) | DE3887463T2 (da) |
| DK (1) | DK626888A (da) |
| ES (1) | ES2061687T3 (da) |
| IL (1) | IL88110A (da) |
| NO (1) | NO170013C (da) |
| NZ (1) | NZ226621A (da) |
| ZA (1) | ZA887991B (da) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3903989A1 (de) * | 1989-02-10 | 1990-09-20 | Basf Ag | Diphenylheteroalkylderivate, ihre herstellung und daraus hergestellte arzneimittel und kosmetika |
| ATE294158T1 (de) | 1997-05-14 | 2005-05-15 | Atherogenics Inc | Ein monoether von probucol und methoden zur hemmung der vcam-1 expression |
| US6670398B2 (en) | 1997-05-14 | 2003-12-30 | Atherogenics, Inc. | Compounds and methods for treating transplant rejection |
| AU2006202461B2 (en) * | 1997-05-14 | 2009-12-03 | Atherogenics, Inc. | Compositions and methods for the inhibition of the expression of VCAM-1 |
| US6852878B2 (en) | 1998-05-14 | 2005-02-08 | Atherogenics, Inc. | Thioketals and thioethers for inhibiting the expression of VCAM-1 |
| EP1695959A1 (en) * | 1997-05-14 | 2006-08-30 | Atherogenics, Inc. | Compouds and methods for the inhibition of the expression of VCAM-1 |
| WO2005102323A2 (en) | 2004-04-20 | 2005-11-03 | Atherogenics, Inc. | Process of preparing esters and ethers of probucol and derivatives thereof |
| AU2008230861A1 (en) | 2007-03-26 | 2008-10-02 | Salutria Pharmaceuticals, Llc | Methods and compositions of derivatives of probucol for the treatment of diabetes |
| WO2020019994A1 (zh) * | 2018-07-25 | 2020-01-30 | 上海挚盟医药科技有限公司 | 一类具有神经保护作用的化合物及其制备方法和用途 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0079855A1 (de) * | 1981-11-12 | 1983-05-25 | Ciba-Geigy Ag | Alkylierte Hydroxyphenylthioalkansäureester |
| EP0218782B1 (en) * | 1985-05-20 | 1990-05-16 | G.D. Searle & Co. | Lipoxygenase-inhibiting composition and hydroxyphenylthioalkylcarbonyl compounds |
| ZA865090B (en) * | 1985-07-22 | 1988-02-24 | Riker Laboratories Inc | Substituted di-t-butylphenols |
| US4755524A (en) * | 1986-01-31 | 1988-07-05 | G. D. Searle & Co. | Novel phenolic thioethers as inhibitors of 5-lipoxygenase |
| ZA882251B (en) * | 1987-04-06 | 1989-11-29 | Riker Laboratories Inc | Substituted di-t-butylphenols |
| US4973731A (en) * | 1987-04-23 | 1990-11-27 | Riker Laboratories, Inc. | Di-t-butylphenyl alkyl and benzyl ether nitriles |
-
1988
- 1988-10-19 NZ NZ226621A patent/NZ226621A/en unknown
- 1988-10-20 CA CA000580766A patent/CA1325431C/en not_active Expired - Fee Related
- 1988-10-20 IL IL88110A patent/IL88110A/xx not_active IP Right Cessation
- 1988-10-25 ZA ZA887991A patent/ZA887991B/xx unknown
- 1988-10-26 NO NO884770A patent/NO170013C/no unknown
- 1988-11-03 AU AU24668/88A patent/AU618764B2/en not_active Ceased
- 1988-11-09 EP EP88310542A patent/EP0317165B1/en not_active Expired - Lifetime
- 1988-11-09 DE DE3887463T patent/DE3887463T2/de not_active Expired - Fee Related
- 1988-11-09 ES ES88310542T patent/ES2061687T3/es not_active Expired - Lifetime
- 1988-11-10 DK DK626888A patent/DK626888A/da not_active Application Discontinuation
- 1988-11-12 KR KR1019880014935A patent/KR890008087A/ko not_active Application Discontinuation
- 1988-11-14 JP JP63287491A patent/JP2520161B2/ja not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP0317165B1 (en) | 1994-01-26 |
| NO884770L (no) | 1989-05-16 |
| ES2061687T3 (es) | 1994-12-16 |
| DE3887463T2 (de) | 1994-08-25 |
| IL88110A0 (en) | 1989-06-30 |
| DE3887463D1 (de) | 1994-03-10 |
| EP0317165A1 (en) | 1989-05-24 |
| KR890008087A (ko) | 1989-07-08 |
| AU2466888A (en) | 1989-05-18 |
| NO884770D0 (no) | 1988-10-26 |
| DK626888A (da) | 1989-06-19 |
| NO170013B (no) | 1992-05-25 |
| DK626888D0 (da) | 1988-11-10 |
| NZ226621A (en) | 1991-12-23 |
| CA1325431C (en) | 1993-12-21 |
| ZA887991B (en) | 1990-06-27 |
| JPH02160A (ja) | 1990-01-05 |
| IL88110A (en) | 1993-01-14 |
| AU618764B2 (en) | 1992-01-09 |
| JP2520161B2 (ja) | 1996-07-31 |
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