NO168585C - Analogifremgangsmaate for fremstilling av terapeutisk aktive pyrazolopyridiner - Google Patents

Analogifremgangsmaate for fremstilling av terapeutisk aktive pyrazolopyridiner

Info

Publication number
NO168585C
NO168585C NO882608A NO882608A NO168585C NO 168585 C NO168585 C NO 168585C NO 882608 A NO882608 A NO 882608A NO 882608 A NO882608 A NO 882608A NO 168585 C NO168585 C NO 168585C
Authority
NO
Norway
Prior art keywords
preparation
group
pyrazolopyridines
formula
lower alkyl
Prior art date
Application number
NO882608A
Other languages
English (en)
Other versions
NO882608D0 (no
NO882608L (no
NO168585B (no
Inventor
Youichi Shiokawa
Atsushi Akahane
Hirohito Katayama
Takafumi Mitsunaga
Original Assignee
Fujisawa Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB878713908A external-priority patent/GB8713908D0/en
Priority claimed from GB878719724A external-priority patent/GB8719724D0/en
Priority claimed from GB878730330A external-priority patent/GB8730330D0/en
Application filed by Fujisawa Pharmaceutical Co filed Critical Fujisawa Pharmaceutical Co
Publication of NO882608D0 publication Critical patent/NO882608D0/no
Publication of NO882608L publication Critical patent/NO882608L/no
Publication of NO168585B publication Critical patent/NO168585B/no
Publication of NO168585C publication Critical patent/NO168585C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Hospice & Palliative Care (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyridine Compounds (AREA)
  • Developing Agents For Electrophotography (AREA)
  • Position Input By Displaying (AREA)
NO882608A 1987-06-15 1988-06-14 Analogifremgangsmaate for fremstilling av terapeutisk aktive pyrazolopyridiner NO168585C (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB878713908A GB8713908D0 (en) 1987-06-15 1987-06-15 Pyrazolopyridine compound
GB878719724A GB8719724D0 (en) 1987-08-20 1987-08-20 Pyrazolopyridine compound
GB878730330A GB8730330D0 (en) 1987-12-31 1987-12-31 Pyrazolopyridine compound & processes for preparation thereof

Publications (4)

Publication Number Publication Date
NO882608D0 NO882608D0 (no) 1988-06-14
NO882608L NO882608L (no) 1988-12-16
NO168585B NO168585B (no) 1991-12-02
NO168585C true NO168585C (no) 1992-03-11

Family

ID=27263458

Family Applications (1)

Application Number Title Priority Date Filing Date
NO882608A NO168585C (no) 1987-06-15 1988-06-14 Analogifremgangsmaate for fremstilling av terapeutisk aktive pyrazolopyridiner

Country Status (16)

Country Link
US (6) US4925849A (no)
EP (1) EP0299209B1 (no)
JP (1) JP2674099B2 (no)
KR (1) KR890000483A (no)
CN (1) CN1031376A (no)
AT (1) ATE127801T1 (no)
AU (1) AU615913B2 (no)
DE (1) DE3854454T2 (no)
DK (1) DK323688A (no)
ES (1) ES2076935T3 (no)
FI (1) FI882813A (no)
GR (1) GR3017850T3 (no)
HU (1) HU200180B (no)
IL (1) IL86674A0 (no)
NO (1) NO168585C (no)
PT (1) PT87700B (no)

Families Citing this family (66)

* Cited by examiner, † Cited by third party
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US4925849A (en) * 1987-06-15 1990-05-15 Fujisawa Pharmaceutical Company, Ltd. Pharmaceutically useful pyrazolopyridines
US5338743A (en) * 1988-06-06 1994-08-16 Fujisawa Pharmaceutical Co., Ltd. New use of the adenosine antagonist
GB8901423D0 (en) * 1989-01-23 1989-03-15 Fujisawa Pharmaceutical Co Pyrazolopyridine compound and processes for preparation thereof
DE3942357A1 (de) * 1989-12-21 1991-06-27 Boehringer Mannheim Gmbh 3-aminopyrazolo-heterocyclen, deren verwendung zur bestimmung von wasserstoffperoxid, wasserstoffperoxid-bildenden systemen, peroxidase, peroxidatisch wirksamen substanzen oder von elektronenreichen aromatischen verbindungen, entsprechende bestimmungsverfahren und hierfuer geeignete mittel
GB9015764D0 (en) * 1990-07-18 1990-09-05 Fujisawa Pharmaceutical Co Pyrazolopyridine compound and processes for preparation thereof
ATE211384T1 (de) * 1991-01-29 2002-01-15 Fujisawa Pharmaceutical Co Verwendung von adenosinantagonisten zur vorbeugung und behandlung von pankreatitis und ulcera
GB9107513D0 (en) * 1991-04-10 1991-05-29 Fujisawa Pharmaceutical Co Pyrazolopyridine compound and processes for preparation thereof
DE69228707T2 (de) * 1992-01-29 1999-10-21 E.I. Du Pont De Nemours And Co., Wilmington Substituierte phenylheterozyklische herbizide
US5670455A (en) * 1992-01-29 1997-09-23 E. I. Du Pont De Nemours And Company Substituted phenylheterocyclic herbicides
US6358885B1 (en) 1992-01-29 2002-03-19 Mississippi State University Substituted phenylheterocyclic herbicides
EP0644762B1 (en) * 1992-06-10 1997-12-17 Fujisawa Pharmaceutical Co., Ltd. Pyrazolopyridine compounds for the treatment of anemia
DK0649425T3 (da) * 1992-06-17 1999-09-27 Upjohn Co Pyridino-, pyrrolidino- og azepino-substituerede oximer, som er anvendelige som anti-atherosklerose- og anti-hypercholester
US5541213A (en) * 1993-06-24 1996-07-30 Eisai Co., Ltd. Propenoic acid derivatives diazole propenoic acid compounds which have useful pharmaceutical utility
AU694157B2 (en) * 1993-12-29 1998-07-16 Fujisawa Pharmaceutical Co., Ltd. Pyrazolopyridine adenosine antagonists
US5646156A (en) * 1994-04-25 1997-07-08 Merck & Co., Inc. Inhibition of eosinophil activation through A3 adenosine receptor antagonism
PT823254E (pt) * 1995-04-27 2003-03-31 Fujisawa Pharmaceutical Co Nova utilizacao de compostos de pirazolopiridina
US6214843B1 (en) * 1996-04-25 2001-04-10 Fujitsawa Pharmaceutical Co., Ltd. Preventives and remedies for ischemic intestinal lesion and ileus
AUPO111096A0 (en) * 1996-07-18 1996-08-08 Fujisawa Pharmaceutical Co., Ltd. New compound
WO1998041237A1 (fr) * 1997-03-18 1998-09-24 Fujisawa Pharmaceutical Co., Ltd. Medicaments pour la prevention et la therapie de l'hyperphosphatemie
EP1568690A1 (en) * 1997-04-22 2005-08-31 Euro-Celtique S.A. The use of carbocyclic and heterocyclic substituted semicarbazones and thiosemicarbazones as sodium channel blockers
KR20010020201A (ko) 1997-04-22 2001-03-15 코센시스 인크 탄소고리 및 헤테로고리 치환된 세미카르바존 및 티오세미카르바존과 그들의 사용 방법
ES2231757T3 (es) 1997-09-05 2005-05-16 Glaxo Group Limited Composiciones farmaceutica que comprenden derivados de 2,3-diaril-pirazolo (1,5-b) piridazina.
AUPP672198A0 (en) * 1998-10-23 1998-11-19 Fujisawa Pharmaceutical Co., Ltd. Pyrazolopyridine compound and pharmaceutical use thereof
US7223772B1 (en) 1998-11-03 2007-05-29 Smithkline Beecham Corporation Pyrazolopyridine derivatives as selective cox-2 inhibitors
WO2000052008A1 (en) 1999-02-27 2000-09-08 Glaxo Group Limited Pyrazolopyridines
US20040152659A1 (en) * 1999-05-12 2004-08-05 Fujisawa Pharmaceutical Co. Ltd. Method for the treatment of parkinson's disease comprising administering an A1A2a receptor dual antagonist
FR2801308B1 (fr) * 1999-11-19 2003-05-09 Oreal COMPOSITIONS DE TEINTURE DE FIBRES KERATINIQUES CONTENANT DE DES 3-AMINO PYRAZOLO-[1,(-a]-PYRIDINES, PROCEDE DE TEINTURE, NOUVELLES 3-AMINO PYRAZOLO-[1,5-a]-PYRIDINES
GB9930358D0 (en) 1999-12-22 2000-02-09 Glaxo Group Ltd Process for the preparation of chemical compounds
PE20020506A1 (es) * 2000-08-22 2002-07-09 Glaxo Group Ltd Derivados de pirazol fusionados como inhibidores de la proteina cinasa
AUPQ969800A0 (en) * 2000-08-28 2000-09-21 Fujisawa Pharmaceutical Co., Ltd. Pyrazolopyridine compound and pharmaceutical use thereof
EP1341788B1 (en) * 2000-12-15 2005-08-10 Glaxo Group Limited Pyrazolopyridines
JP2004515550A (ja) * 2000-12-15 2004-05-27 グラクソ グループ リミテッド 治療用化合物
TWI312347B (en) 2001-02-08 2009-07-21 Eisai R&D Man Co Ltd Bicyclic nitrogen-containing condensed ring compounds
AU2002248531A1 (en) * 2001-03-08 2002-09-24 Smithkline Beecham Corporation Pyrazolopyriadine derivatives
JP4237497B2 (ja) * 2001-03-30 2009-03-11 スミスクライン ビーチャム コーポレーション ピラゾロピリジン類、その調製方法及びその治療用化合物としての使用
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WO2002083672A1 (en) * 2001-04-10 2002-10-24 Smithkline Beecham Corporation Antiviral pyrazolopyridine compounds
EP1389618B1 (en) * 2001-04-27 2011-06-15 Eisai R&D Management Co., Ltd. Pyrazolo 1,5-a pyridines and medicines containing the same
US6756498B2 (en) 2001-04-27 2004-06-29 Smithkline Beecham Corporation Process for the preparation of chemical compounds
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AUPR548601A0 (en) * 2001-06-06 2001-06-28 Fujisawa Pharmaceutical Co., Ltd. Pyrazolopyrazinecompound and pharmaceutical use thereof
WO2003000689A1 (en) * 2001-06-21 2003-01-03 Smithkline Beecham Corporation Imidazo`1,2-a!pyridine derivatives for the prophylaxis and treatment of herpes viral infections
EP1423389B1 (en) * 2001-09-07 2007-06-06 SmithKline Beecham Corporation Pyrazolo-pyridines for the treatment of herpes infections
WO2003031446A1 (en) * 2001-10-05 2003-04-17 Smithkline Beecham Corporation Imidazo-pyridine derivatives for use in the treatment of herpes viral infection
US7199120B2 (en) * 2001-12-11 2007-04-03 Smithkline Beecham Corporation Pyrazolo-pyridine derivatives as antiherpes agents
US20040021778A1 (en) * 2002-08-05 2004-02-05 Oldani Jerome L. Security system with remote access and control
AU2003275266A1 (en) * 2002-10-03 2004-05-04 Smithkline Beecham Corporation Therapeutic compounds based on pyrazolopyridine derivatives
PT1555265E (pt) * 2002-10-22 2009-05-12 Eisai R&D Man Co Ltd Compostos de 7-fenil pirazolopiridina
US7176216B2 (en) * 2002-10-22 2007-02-13 Eisai Co., Ltd. 7-phenylpyrazolopyridine compounds
TW200517114A (en) 2003-10-15 2005-06-01 Combinatorx Inc Methods and reagents for the treatment of immunoinflammatory disorders
EP1689390B1 (en) 2003-11-21 2011-02-09 Zalicus Inc. Methods and reagents for the treatment of inflammatory disorders
ZA200804550B (en) 2005-11-09 2009-08-26 Combinatorx Inc Methods, compositions, and kits for the treatment of medical conditions
AU2007258567B2 (en) * 2006-06-06 2012-04-19 Medicinova, Inc. Substituted pyrazolo (1,5-alpha) pyridine compounds and their methods of use
EP1939180A1 (en) * 2006-12-20 2008-07-02 sanofi-aventis Heteroarylacrylamides and their use as pharmaceuticals for the stimulation of the expression of endothelial NO synthase
US7536799B2 (en) * 2007-06-07 2009-05-26 Keson Industries Chalk line apparatus with strategically located chalk fill opening
JP4654325B2 (ja) * 2008-04-15 2011-03-16 エーザイ・アール・アンド・ディー・マネジメント株式会社 ３−フェニルピラゾロ［５，１−ｂ］チアゾール化合物
US20100092479A1 (en) * 2008-08-18 2010-04-15 Combinatorx (Singapore) Pte. Ltd. Compositions and methods for treatment of viral diseases
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AR078521A1 (es) * 2009-10-08 2011-11-16 Eisai R&D Man Co Ltd Compuesto pirazolotiazol
EP2487177A1 (en) * 2009-10-08 2012-08-15 Eisai R&D Management Co., Ltd. Pyrazoloxazole compound
UY34763A (es) 2012-04-26 2013-10-31 Bristol Myers Squibb Co Inhibidores de la agregación plaquetaria
WO2013163241A1 (en) 2012-04-26 2013-10-31 Bristol-Myers Squibb Company Imidazothiadiazole and imidazopyridazine derivatives as protease activated receptor 4 (par4) inhibitors for treating platelet aggregation
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US9617279B1 (en) 2014-06-24 2017-04-11 Bristol-Myers Squibb Company Imidazooxadiazole compounds
US9598419B1 (en) 2014-06-24 2017-03-21 Universite De Montreal Imidazotriazine and imidazodiazine compounds
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JPS5229318B2 (no) * 1972-03-30 1977-08-01
US4017597A (en) * 1974-10-30 1977-04-12 Monsanto Company Unitized solid phase immunoassay kit and method
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JPS5154583A (en) * 1974-11-01 1976-05-13 Kyorin Seiyaku Kk Shinkipirazoro * 1 55a * pirijinjudotaino seizoho
JPS595185A (ja) * 1982-06-16 1984-01-12 メイ・アンド・ベイガ−・リミテツド 新規なピラゾロピリジン誘導体
JPS60248689A (ja) * 1984-05-24 1985-12-09 Mitsubishi Paper Mills Ltd ３−（３′−ピラゾロ〔１，５−ａ〕ピリジル）アクロレイン誘導体
US4925849A (en) * 1987-06-15 1990-05-15 Fujisawa Pharmaceutical Company, Ltd. Pharmaceutically useful pyrazolopyridines

Also Published As

Publication number Publication date
EP0299209A3 (en) 1990-05-09
JP2674099B2 (ja) 1997-11-05
US5102869A (en) 1992-04-07
HUT47110A (en) 1989-01-30
EP0299209B1 (en) 1995-09-13
GR3017850T3 (en) 1996-01-31
NO882608D0 (no) 1988-06-14
US4994453A (en) 1991-02-19
FI882813A0 (fi) 1988-06-13
DE3854454T2 (de) 1996-02-15
ATE127801T1 (de) 1995-09-15
US4925849A (en) 1990-05-15
CN1031376A (zh) 1989-03-01
US5102878A (en) 1992-04-07
PT87700B (pt) 1992-10-30
IL86674A0 (en) 1988-11-30
EP0299209A2 (en) 1989-01-18
AU615913B2 (en) 1991-10-17
DK323688A (da) 1988-12-16
DE3854454D1 (de) 1995-10-19
KR890000483A (ko) 1989-03-14
HU200180B (en) 1990-04-28
FI882813A (fi) 1988-12-16
NO882608L (no) 1988-12-16
US5087629A (en) 1992-02-11
AU1760288A (en) 1988-12-15
ES2076935T3 (es) 1995-11-16
US5296490A (en) 1994-03-22
NO168585B (no) 1991-12-02
PT87700A (pt) 1988-07-01
JPS6445385A (en) 1989-02-17
DK323688D0 (da) 1988-06-14

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