NO166528C - ANALOGY PROCEDURE FOR THE PREPARATION OF THERAPEUTICALLY ACTIVE NAPHALAND AND INDANDER DERIVATIVES. - Google Patents

ANALOGY PROCEDURE FOR THE PREPARATION OF THERAPEUTICALLY ACTIVE NAPHALAND AND INDANDER DERIVATIVES.

Info

Publication number
NO166528C
NO166528C NO873784A NO873784A NO166528C NO 166528 C NO166528 C NO 166528C NO 873784 A NO873784 A NO 873784A NO 873784 A NO873784 A NO 873784A NO 166528 C NO166528 C NO 166528C
Authority
NO
Norway
Prior art keywords
derivatives
naphaland
indander
preparation
therapeutically active
Prior art date
Application number
NO873784A
Other languages
Norwegian (no)
Other versions
NO166528B (en
NO873784L (en
NO873784D0 (en
Inventor
Manfred Psiorz
Joachim Heider
Andreas Bomhard
Norbert Hauel
Klaus Noll
Berthold Narr
Christian Lillie
Walter Kobinger
Juergen Daemmgen
Original Assignee
Thomae Gmbh Dr K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K
Publication of NO873784D0 publication Critical patent/NO873784D0/en
Publication of NO873784L publication Critical patent/NO873784L/en
Publication of NO166528B publication Critical patent/NO166528B/en
Publication of NO166528C publication Critical patent/NO166528C/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/385—Saturated compounds containing a keto group being part of a ring
    • C07C49/417—Saturated compounds containing a keto group being part of a ring polycyclic
    • C07C49/423—Saturated compounds containing a keto group being part of a ring polycyclic a keto group being part of a condensed ring system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/50—Organo-phosphines
    • C07F9/53—Organo-phosphine oxides; Organo-phosphine thioxides
    • C07F9/5304—Acyclic saturated phosphine oxides or thioxides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Cardiology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Feedback Control In General (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)

Abstract

Naphthalene and indane derivatives of the formula <IMAGE> in which the substituents have the meaning given in the description, their enantiomers, their diastereomers and their acid addition salts with inorganic or organic acids which have useful pharmacological properties, in particular a heart rate-reducing action. The novel compounds can be prepared by processes known per se.
NO873784A 1986-09-11 1987-09-10 ANALOGY PROCEDURE FOR THE PREPARATION OF THERAPEUTICALLY ACTIVE NAPHALAND AND INDANDER DERIVATIVES. NO166528C (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19863630903 DE3630903A1 (en) 1986-09-11 1986-09-11 NEW TETRAHYDRONAPHTHALINE AND INDANDERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND THE MEDICINAL PRODUCTS CONTAINING THEM

Publications (4)

Publication Number Publication Date
NO873784D0 NO873784D0 (en) 1987-09-10
NO873784L NO873784L (en) 1988-03-14
NO166528B NO166528B (en) 1991-04-29
NO166528C true NO166528C (en) 1991-08-07

Family

ID=6309344

Family Applications (1)

Application Number Title Priority Date Filing Date
NO873784A NO166528C (en) 1986-09-11 1987-09-10 ANALOGY PROCEDURE FOR THE PREPARATION OF THERAPEUTICALLY ACTIVE NAPHALAND AND INDANDER DERIVATIVES.

Country Status (16)

Country Link
EP (1) EP0259782B1 (en)
JP (1) JPS6377842A (en)
KR (1) KR880003889A (en)
AT (1) ATE59378T1 (en)
AU (1) AU597719B2 (en)
DD (1) DD263525A5 (en)
DE (2) DE3630903A1 (en)
DK (1) DK472387A (en)
FI (1) FI873917A (en)
HU (1) HU206077B (en)
IL (1) IL83850A (en)
NO (1) NO166528C (en)
NZ (1) NZ221766A (en)
PH (1) PH25680A (en)
PT (1) PT85689B (en)
ZA (1) ZA876768B (en)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8809314D0 (en) * 1988-04-20 1988-05-25 Wellcome Found Anti-hypertensive sulfonanilides
ES2055011T3 (en) * 1988-09-19 1994-08-16 Akzo Nv A PROCEDURE FOR THE PREPARATION OF DERIVATIVES OF TETRAHIDRONAFTALENO AND INDANO.
JP2931986B2 (en) * 1989-02-17 1999-08-09 武田薬品工業株式会社 Aralkylamine derivatives
US5166209A (en) * 1989-04-21 1992-11-24 Burroughs Wellcome Co. Pharmacologically active compounds
US5643784A (en) * 1990-12-04 1997-07-01 H, Lundbeck A/S Indan derivatives
NZ243065A (en) * 1991-06-13 1995-07-26 Lundbeck & Co As H Piperidine derivatives and pharmaceutical compositions
SE9103745D0 (en) * 1991-12-18 1991-12-18 Wikstroem Haakan ARYL-TRIFLATES AND RELATED COMPOUNDS
DK78692D0 (en) * 1992-06-12 1992-06-12 Lundbeck & Co As H DIMER PIPERIDINE AND PIPERAZINE DERIVATIVES
US5508306A (en) * 1992-11-13 1996-04-16 Synaptic Pharmaceutical Corporation Aromatic amine derivatives
DE69411747T2 (en) * 1993-09-09 1999-02-04 Smithkline Beecham P.L.C., Brentford, Middlesex PHOSPHINIC ACID DERIVATIVES WITH ANTI-HYPERGLYZEMIA AND / OR ANTI-FETISH ADDICTION
US6048877A (en) * 1997-02-21 2000-04-11 Bristol-Myers Squibb Company Tetralone derivatives as antiarrhythmic agents
ATE390404T1 (en) 1997-02-27 2008-04-15 Takeda Pharmaceutical AMINE DERIVATIVES, THEIR PREPARATION AND USE AS INHIBITORS OF AMYLOID-BETA PRODUCTION
ES2312423T3 (en) 2000-04-03 2009-03-01 Takeda Pharmaceutical Company Limited PROCEDURE TO PRODUCE AMINA DERIVATIVES.

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CS159795B2 (en) * 1971-04-19 1975-01-31
CH654294A5 (en) * 1982-07-09 1986-02-14 Yason Srl CARDIAC AND CEREBRAL LEVEL CALCIUM BLOCKING COMPOUNDS, METHOD FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS.
NZ213651A (en) * 1984-10-11 1989-07-27 Hoffmann La Roche Tetrahydronapthalene derivatives and medicaments
DK691488A (en) * 1987-12-14 1989-06-15 Beecham Group Plc UNKNOWN RELATIONSHIPS

Also Published As

Publication number Publication date
DE3767094D1 (en) 1991-02-07
NO166528B (en) 1991-04-29
NZ221766A (en) 1989-05-29
DD263525A5 (en) 1989-01-04
PH25680A (en) 1991-09-04
AU7829787A (en) 1988-03-17
IL83850A (en) 1991-09-16
DK472387D0 (en) 1987-09-10
IL83850A0 (en) 1988-02-29
HUT46885A (en) 1988-12-28
ZA876768B (en) 1989-05-30
NO873784L (en) 1988-03-14
PT85689B (en) 1990-06-29
EP0259782A1 (en) 1988-03-16
PT85689A (en) 1987-10-01
HU206077B (en) 1992-08-28
ATE59378T1 (en) 1991-01-15
EP0259782B1 (en) 1990-12-27
FI873917A (en) 1988-03-12
AU597719B2 (en) 1990-06-07
NO873784D0 (en) 1987-09-10
DK472387A (en) 1988-03-12
DE3630903A1 (en) 1988-03-24
KR880003889A (en) 1988-05-30
FI873917A0 (en) 1987-09-10
JPS6377842A (en) 1988-04-08

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