NZ221766A - 2-aminoalkyl napthalene or indan derivatives and pharmaceutical compositions - Google Patents
2-aminoalkyl napthalene or indan derivatives and pharmaceutical compositionsInfo
- Publication number
- NZ221766A NZ221766A NZ221766A NZ22176687A NZ221766A NZ 221766 A NZ221766 A NZ 221766A NZ 221766 A NZ221766 A NZ 221766A NZ 22176687 A NZ22176687 A NZ 22176687A NZ 221766 A NZ221766 A NZ 221766A
- Authority
- NZ
- New Zealand
- Prior art keywords
- napthalene
- aminoalkyl
- pharmaceutical compositions
- indan derivatives
- derivatives
- Prior art date
Links
- PQNFLJBBNBOBRQ-UHFFFAOYSA-N indane Chemical class C1=CC=C2CCCC2=C1 PQNFLJBBNBOBRQ-UHFFFAOYSA-N 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- UFWIBTONFRDIAS-UHFFFAOYSA-N Naphthalene Chemical compound C1=CC=CC2=CC=CC=C21 UFWIBTONFRDIAS-UHFFFAOYSA-N 0.000 abstract 2
- HBAQYPYDRFILMT-UHFFFAOYSA-N 8-[3-(1-cyclopropylpyrazol-4-yl)-1H-pyrazolo[4,3-d]pyrimidin-5-yl]-3-methyl-3,8-diazabicyclo[3.2.1]octan-2-one Chemical class C1(CC1)N1N=CC(=C1)C1=NNC2=C1N=C(N=C2)N1C2C(N(CC1CC2)C)=O HBAQYPYDRFILMT-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000003392 indanyl group Chemical class C1(CCC2=CC=CC=C12)* 0.000 abstract 1
- 150000007522 mineralic acids Chemical class 0.000 abstract 1
- 150000007524 organic acids Chemical class 0.000 abstract 1
- 235000005985 organic acids Nutrition 0.000 abstract 1
- 230000000144 pharmacologic effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/385—Saturated compounds containing a keto group being part of a ring
- C07C49/417—Saturated compounds containing a keto group being part of a ring polycyclic
- C07C49/423—Saturated compounds containing a keto group being part of a ring polycyclic a keto group being part of a condensed ring system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/50—Organo-phosphines
- C07F9/53—Organo-phosphine oxides; Organo-phosphine thioxides
- C07F9/5304—Acyclic saturated phosphine oxides or thioxides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Heart & Thoracic Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- Cardiology (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Feedback Control In General (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
Abstract
Naphthalene and indane derivatives of the formula <IMAGE> in which the substituents have the meaning given in the description, their enantiomers, their diastereomers and their acid addition salts with inorganic or organic acids which have useful pharmacological properties, in particular a heart rate-reducing action. The novel compounds can be prepared by processes known per se.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19863630903 DE3630903A1 (en) | 1986-09-11 | 1986-09-11 | NEW TETRAHYDRONAPHTHALINE AND INDANDERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND THE MEDICINAL PRODUCTS CONTAINING THEM |
Publications (1)
Publication Number | Publication Date |
---|---|
NZ221766A true NZ221766A (en) | 1989-05-29 |
Family
ID=6309344
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NZ221766A NZ221766A (en) | 1986-09-11 | 1987-09-09 | 2-aminoalkyl napthalene or indan derivatives and pharmaceutical compositions |
Country Status (16)
Country | Link |
---|---|
EP (1) | EP0259782B1 (en) |
JP (1) | JPS6377842A (en) |
KR (1) | KR880003889A (en) |
AT (1) | ATE59378T1 (en) |
AU (1) | AU597719B2 (en) |
DD (1) | DD263525A5 (en) |
DE (2) | DE3630903A1 (en) |
DK (1) | DK472387A (en) |
FI (1) | FI873917A (en) |
HU (1) | HU206077B (en) |
IL (1) | IL83850A (en) |
NO (1) | NO166528C (en) |
NZ (1) | NZ221766A (en) |
PH (1) | PH25680A (en) |
PT (1) | PT85689B (en) |
ZA (1) | ZA876768B (en) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8809314D0 (en) * | 1988-04-20 | 1988-05-25 | Wellcome Found | Anti-hypertensive sulfonanilides |
ES2055011T3 (en) * | 1988-09-19 | 1994-08-16 | Akzo Nv | A PROCEDURE FOR THE PREPARATION OF DERIVATIVES OF TETRAHIDRONAFTALENO AND INDANO. |
JP2931986B2 (en) * | 1989-02-17 | 1999-08-09 | 武田薬品工業株式会社 | Aralkylamine derivatives |
US5166209A (en) * | 1989-04-21 | 1992-11-24 | Burroughs Wellcome Co. | Pharmacologically active compounds |
US5643784A (en) * | 1990-12-04 | 1997-07-01 | H, Lundbeck A/S | Indan derivatives |
NZ243065A (en) * | 1991-06-13 | 1995-07-26 | Lundbeck & Co As H | Piperidine derivatives and pharmaceutical compositions |
SE9103745D0 (en) * | 1991-12-18 | 1991-12-18 | Wikstroem Haakan | ARYL-TRIFLATES AND RELATED COMPOUNDS |
DK78692D0 (en) * | 1992-06-12 | 1992-06-12 | Lundbeck & Co As H | DIMER PIPERIDINE AND PIPERAZINE DERIVATIVES |
US5508306A (en) * | 1992-11-13 | 1996-04-16 | Synaptic Pharmaceutical Corporation | Aromatic amine derivatives |
AU7692394A (en) * | 1993-09-09 | 1995-03-27 | Smithkline Beecham Plc | Phosphinic acid derivatives with anti-hyper glycemic and/or anti-obesity activity |
US6048877A (en) * | 1997-02-21 | 2000-04-11 | Bristol-Myers Squibb Company | Tetralone derivatives as antiarrhythmic agents |
ES2300119T3 (en) | 1997-02-27 | 2008-06-01 | Takeda Pharmaceutical Company Limited | AMINA COMPOUNDS, ITS PRODUCTION AND ITS USE AS INHIBITORS OF THE PRODUCTION OF BETA-AMILOID. |
US6784314B2 (en) | 2000-04-03 | 2004-08-31 | Takeda Chemical Industries, Ltd. | Process for producing amine derivatives |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CS159795B2 (en) * | 1971-04-19 | 1975-01-31 | ||
CH654294A5 (en) * | 1982-07-09 | 1986-02-14 | Yason Srl | CARDIAC AND CEREBRAL LEVEL CALCIUM BLOCKING COMPOUNDS, METHOD FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS. |
NZ213651A (en) * | 1984-10-11 | 1989-07-27 | Hoffmann La Roche | Tetrahydronapthalene derivatives and medicaments |
DK691488A (en) * | 1987-12-14 | 1989-06-15 | Beecham Group Plc | UNKNOWN RELATIONSHIPS |
-
1986
- 1986-09-11 DE DE19863630903 patent/DE3630903A1/en not_active Withdrawn
-
1987
- 1987-09-03 DE DE8787112865T patent/DE3767094D1/en not_active Expired - Fee Related
- 1987-09-03 EP EP87112865A patent/EP0259782B1/en not_active Expired - Lifetime
- 1987-09-03 AT AT87112865T patent/ATE59378T1/en not_active IP Right Cessation
- 1987-09-09 DD DD87306821A patent/DD263525A5/en not_active IP Right Cessation
- 1987-09-09 NZ NZ221766A patent/NZ221766A/en unknown
- 1987-09-10 PH PH35795A patent/PH25680A/en unknown
- 1987-09-10 IL IL83850A patent/IL83850A/en not_active IP Right Cessation
- 1987-09-10 FI FI873917A patent/FI873917A/en not_active IP Right Cessation
- 1987-09-10 NO NO873784A patent/NO166528C/en unknown
- 1987-09-10 KR KR870010008A patent/KR880003889A/en not_active Application Discontinuation
- 1987-09-10 HU HU874035A patent/HU206077B/en unknown
- 1987-09-10 ZA ZA876768A patent/ZA876768B/en unknown
- 1987-09-10 DK DK472387A patent/DK472387A/en not_active Application Discontinuation
- 1987-09-10 JP JP62227532A patent/JPS6377842A/en active Pending
- 1987-09-11 PT PT85689A patent/PT85689B/en not_active IP Right Cessation
- 1987-09-11 AU AU78297/87A patent/AU597719B2/en not_active Ceased
Also Published As
Publication number | Publication date |
---|---|
IL83850A (en) | 1991-09-16 |
ZA876768B (en) | 1989-05-30 |
DE3767094D1 (en) | 1991-02-07 |
NO873784D0 (en) | 1987-09-10 |
HUT46885A (en) | 1988-12-28 |
HU206077B (en) | 1992-08-28 |
PT85689B (en) | 1990-06-29 |
JPS6377842A (en) | 1988-04-08 |
IL83850A0 (en) | 1988-02-29 |
NO166528B (en) | 1991-04-29 |
DK472387A (en) | 1988-03-12 |
NO873784L (en) | 1988-03-14 |
EP0259782B1 (en) | 1990-12-27 |
PT85689A (en) | 1987-10-01 |
NO166528C (en) | 1991-08-07 |
FI873917A0 (en) | 1987-09-10 |
AU597719B2 (en) | 1990-06-07 |
AU7829787A (en) | 1988-03-17 |
KR880003889A (en) | 1988-05-30 |
EP0259782A1 (en) | 1988-03-16 |
DK472387D0 (en) | 1987-09-10 |
DD263525A5 (en) | 1989-01-04 |
ATE59378T1 (en) | 1991-01-15 |
FI873917A (en) | 1988-03-12 |
PH25680A (en) | 1991-09-04 |
DE3630903A1 (en) | 1988-03-24 |
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