NZ221766A - 2-aminoalkyl napthalene or indan derivatives and pharmaceutical compositions - Google Patents

2-aminoalkyl napthalene or indan derivatives and pharmaceutical compositions

Info

Publication number
NZ221766A
NZ221766A NZ221766A NZ22176687A NZ221766A NZ 221766 A NZ221766 A NZ 221766A NZ 221766 A NZ221766 A NZ 221766A NZ 22176687 A NZ22176687 A NZ 22176687A NZ 221766 A NZ221766 A NZ 221766A
Authority
NZ
New Zealand
Prior art keywords
napthalene
aminoalkyl
pharmaceutical compositions
indan derivatives
derivatives
Prior art date
Application number
NZ221766A
Inventor
M Psiorz
J Heider
A Bomhard
N Hauel
K Noll
B Narr
C Lillie
W Kobinger
J Dammgen
Original Assignee
Thomae Gmbh Dr K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K
Publication of NZ221766A publication Critical patent/NZ221766A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/385Saturated compounds containing a keto group being part of a ring
    • C07C49/417Saturated compounds containing a keto group being part of a ring polycyclic
    • C07C49/423Saturated compounds containing a keto group being part of a ring polycyclic a keto group being part of a condensed ring system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/50Organo-phosphines
    • C07F9/53Organo-phosphine oxides; Organo-phosphine thioxides
    • C07F9/5304Acyclic saturated phosphine oxides or thioxides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Cardiology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Feedback Control In General (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)

Abstract

Naphthalene and indane derivatives of the formula <IMAGE> in which the substituents have the meaning given in the description, their enantiomers, their diastereomers and their acid addition salts with inorganic or organic acids which have useful pharmacological properties, in particular a heart rate-reducing action. The novel compounds can be prepared by processes known per se.
NZ221766A 1986-09-11 1987-09-09 2-aminoalkyl napthalene or indan derivatives and pharmaceutical compositions NZ221766A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19863630903 DE3630903A1 (en) 1986-09-11 1986-09-11 NEW TETRAHYDRONAPHTHALINE AND INDANDERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND THE MEDICINAL PRODUCTS CONTAINING THEM

Publications (1)

Publication Number Publication Date
NZ221766A true NZ221766A (en) 1989-05-29

Family

ID=6309344

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ221766A NZ221766A (en) 1986-09-11 1987-09-09 2-aminoalkyl napthalene or indan derivatives and pharmaceutical compositions

Country Status (16)

Country Link
EP (1) EP0259782B1 (en)
JP (1) JPS6377842A (en)
KR (1) KR880003889A (en)
AT (1) ATE59378T1 (en)
AU (1) AU597719B2 (en)
DD (1) DD263525A5 (en)
DE (2) DE3630903A1 (en)
DK (1) DK472387A (en)
FI (1) FI873917A (en)
HU (1) HU206077B (en)
IL (1) IL83850A (en)
NO (1) NO166528C (en)
NZ (1) NZ221766A (en)
PH (1) PH25680A (en)
PT (1) PT85689B (en)
ZA (1) ZA876768B (en)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8809314D0 (en) * 1988-04-20 1988-05-25 Wellcome Found Anti-hypertensive sulfonanilides
ES2055011T3 (en) * 1988-09-19 1994-08-16 Akzo Nv A PROCEDURE FOR THE PREPARATION OF DERIVATIVES OF TETRAHIDRONAFTALENO AND INDANO.
JP2931986B2 (en) * 1989-02-17 1999-08-09 武田薬品工業株式会社 Aralkylamine derivatives
US5166209A (en) * 1989-04-21 1992-11-24 Burroughs Wellcome Co. Pharmacologically active compounds
US5643784A (en) * 1990-12-04 1997-07-01 H, Lundbeck A/S Indan derivatives
NZ243065A (en) * 1991-06-13 1995-07-26 Lundbeck & Co As H Piperidine derivatives and pharmaceutical compositions
SE9103745D0 (en) * 1991-12-18 1991-12-18 Wikstroem Haakan ARYL-TRIFLATES AND RELATED COMPOUNDS
DK78692D0 (en) * 1992-06-12 1992-06-12 Lundbeck & Co As H DIMER PIPERIDINE AND PIPERAZINE DERIVATIVES
US5508306A (en) * 1992-11-13 1996-04-16 Synaptic Pharmaceutical Corporation Aromatic amine derivatives
AU7692394A (en) * 1993-09-09 1995-03-27 Smithkline Beecham Plc Phosphinic acid derivatives with anti-hyper glycemic and/or anti-obesity activity
US6048877A (en) * 1997-02-21 2000-04-11 Bristol-Myers Squibb Company Tetralone derivatives as antiarrhythmic agents
ES2300119T3 (en) 1997-02-27 2008-06-01 Takeda Pharmaceutical Company Limited AMINA COMPOUNDS, ITS PRODUCTION AND ITS USE AS INHIBITORS OF THE PRODUCTION OF BETA-AMILOID.
US6784314B2 (en) 2000-04-03 2004-08-31 Takeda Chemical Industries, Ltd. Process for producing amine derivatives

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CS159795B2 (en) * 1971-04-19 1975-01-31
CH654294A5 (en) * 1982-07-09 1986-02-14 Yason Srl CARDIAC AND CEREBRAL LEVEL CALCIUM BLOCKING COMPOUNDS, METHOD FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS.
NZ213651A (en) * 1984-10-11 1989-07-27 Hoffmann La Roche Tetrahydronapthalene derivatives and medicaments
DK691488A (en) * 1987-12-14 1989-06-15 Beecham Group Plc UNKNOWN RELATIONSHIPS

Also Published As

Publication number Publication date
IL83850A (en) 1991-09-16
ZA876768B (en) 1989-05-30
DE3767094D1 (en) 1991-02-07
NO873784D0 (en) 1987-09-10
HUT46885A (en) 1988-12-28
HU206077B (en) 1992-08-28
PT85689B (en) 1990-06-29
JPS6377842A (en) 1988-04-08
IL83850A0 (en) 1988-02-29
NO166528B (en) 1991-04-29
DK472387A (en) 1988-03-12
NO873784L (en) 1988-03-14
EP0259782B1 (en) 1990-12-27
PT85689A (en) 1987-10-01
NO166528C (en) 1991-08-07
FI873917A0 (en) 1987-09-10
AU597719B2 (en) 1990-06-07
AU7829787A (en) 1988-03-17
KR880003889A (en) 1988-05-30
EP0259782A1 (en) 1988-03-16
DK472387D0 (en) 1987-09-10
DD263525A5 (en) 1989-01-04
ATE59378T1 (en) 1991-01-15
FI873917A (en) 1988-03-12
PH25680A (en) 1991-09-04
DE3630903A1 (en) 1988-03-24

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