IL83850A0 - Naphthalene and indan derivatives,their preparation and pharmaceutical compositions containing them - Google Patents

Naphthalene and indan derivatives,their preparation and pharmaceutical compositions containing them

Info

Publication number
IL83850A0
IL83850A0 IL83850A IL8385087A IL83850A0 IL 83850 A0 IL83850 A0 IL 83850A0 IL 83850 A IL83850 A IL 83850A IL 8385087 A IL8385087 A IL 8385087A IL 83850 A0 IL83850 A0 IL 83850A0
Authority
IL
Israel
Prior art keywords
naphthalene
preparation
pharmaceutical compositions
compositions containing
indan derivatives
Prior art date
Application number
IL83850A
Other versions
IL83850A (en
Original Assignee
Thomae Gmbh Dr K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K
Publication of IL83850A0 publication Critical patent/IL83850A0/en
Publication of IL83850A publication Critical patent/IL83850A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/50—Organo-phosphines
    • C07F9/53—Organo-phosphine oxides; Organo-phosphine thioxides
    • C07F9/5304—Acyclic saturated phosphine oxides or thioxides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/385—Saturated compounds containing a keto group being part of a ring
    • C07C49/417—Saturated compounds containing a keto group being part of a ring polycyclic
    • C07C49/423—Saturated compounds containing a keto group being part of a ring polycyclic a keto group being part of a condensed ring system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Abstract

Naphthalene and indane derivatives of the formula <IMAGE> in which the substituents have the meaning given in the description, their enantiomers, their diastereomers and their acid addition salts with inorganic or organic acids which have useful pharmacological properties, in particular a heart rate-reducing action. The novel compounds can be prepared by processes known per se.
IL83850A 1986-09-11 1987-09-10 N-phenylalkyl-amino-alkyl-tetrahydronaphthalene or indane derivatives,their preparation and pharmaceutical compositions containing them IL83850A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19863630903 DE3630903A1 (en) 1986-09-11 1986-09-11 NEW TETRAHYDRONAPHTHALINE AND INDANDERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND THE MEDICINAL PRODUCTS CONTAINING THEM

Publications (2)

Publication Number Publication Date
IL83850A0 true IL83850A0 (en) 1988-02-29
IL83850A IL83850A (en) 1991-09-16

Family

ID=6309344

Family Applications (1)

Application Number Title Priority Date Filing Date
IL83850A IL83850A (en) 1986-09-11 1987-09-10 N-phenylalkyl-amino-alkyl-tetrahydronaphthalene or indane derivatives,their preparation and pharmaceutical compositions containing them

Country Status (16)

Country Link
EP (1) EP0259782B1 (en)
JP (1) JPS6377842A (en)
KR (1) KR880003889A (en)
AT (1) ATE59378T1 (en)
AU (1) AU597719B2 (en)
DD (1) DD263525A5 (en)
DE (2) DE3630903A1 (en)
DK (1) DK472387A (en)
FI (1) FI873917A (en)
HU (1) HU206077B (en)
IL (1) IL83850A (en)
NO (1) NO166528C (en)
NZ (1) NZ221766A (en)
PH (1) PH25680A (en)
PT (1) PT85689B (en)
ZA (1) ZA876768B (en)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8809314D0 (en) * 1988-04-20 1988-05-25 Wellcome Found Anti-hypertensive sulfonanilides
ES2055011T3 (en) * 1988-09-19 1994-08-16 Akzo Nv A PROCEDURE FOR THE PREPARATION OF DERIVATIVES OF TETRAHIDRONAFTALENO AND INDANO.
JP2931986B2 (en) * 1989-02-17 1999-08-09 武田薬品工業株式会社 Aralkylamine derivatives
US5166209A (en) * 1989-04-21 1992-11-24 Burroughs Wellcome Co. Pharmacologically active compounds
US5643784A (en) * 1990-12-04 1997-07-01 H, Lundbeck A/S Indan derivatives
NZ243065A (en) * 1991-06-13 1995-07-26 Lundbeck & Co As H Piperidine derivatives and pharmaceutical compositions
SE9103745D0 (en) * 1991-12-18 1991-12-18 Wikstroem Haakan ARYL-TRIFLATES AND RELATED COMPOUNDS
DK78692D0 (en) * 1992-06-12 1992-06-12 Lundbeck & Co As H DIMER PIPERIDINE AND PIPERAZINE DERIVATIVES
US5508306A (en) * 1992-11-13 1996-04-16 Synaptic Pharmaceutical Corporation Aromatic amine derivatives
AU7692394A (en) * 1993-09-09 1995-03-27 Smithkline Beecham Plc Phosphinic acid derivatives with anti-hyper glycemic and/or anti-obesity activity
US6048877A (en) * 1997-02-21 2000-04-11 Bristol-Myers Squibb Company Tetralone derivatives as antiarrhythmic agents
CA2276278C (en) 1997-02-27 2009-04-07 Takeda Chemical Industries, Ltd. Amine compounds, their production and use
DE60136446D1 (en) 2000-04-03 2008-12-18 Takeda Pharmaceutical PROCESS FOR THE PREPARATION OF AMINE DERIVATIVES

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CS159795B2 (en) * 1971-04-19 1975-01-31
CH654294A5 (en) * 1982-07-09 1986-02-14 Yason Srl CARDIAC AND CEREBRAL LEVEL CALCIUM BLOCKING COMPOUNDS, METHOD FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS.
NZ213651A (en) * 1984-10-11 1989-07-27 Hoffmann La Roche Tetrahydronapthalene derivatives and medicaments
DK691488A (en) * 1987-12-14 1989-06-15 Beecham Group Plc UNKNOWN RELATIONSHIPS

Also Published As

Publication number Publication date
EP0259782A1 (en) 1988-03-16
DD263525A5 (en) 1989-01-04
NO873784D0 (en) 1987-09-10
NO166528C (en) 1991-08-07
PT85689B (en) 1990-06-29
IL83850A (en) 1991-09-16
AU597719B2 (en) 1990-06-07
HU206077B (en) 1992-08-28
FI873917A (en) 1988-03-12
NO166528B (en) 1991-04-29
NZ221766A (en) 1989-05-29
ZA876768B (en) 1989-05-30
FI873917A0 (en) 1987-09-10
EP0259782B1 (en) 1990-12-27
ATE59378T1 (en) 1991-01-15
PH25680A (en) 1991-09-04
JPS6377842A (en) 1988-04-08
AU7829787A (en) 1988-03-17
KR880003889A (en) 1988-05-30
DK472387A (en) 1988-03-12
DE3630903A1 (en) 1988-03-24
DK472387D0 (en) 1987-09-10
NO873784L (en) 1988-03-14
HUT46885A (en) 1988-12-28
DE3767094D1 (en) 1991-02-07
PT85689A (en) 1987-10-01

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IL83850A0 (en) Naphthalene and indan derivatives,their preparation and pharmaceutical compositions containing them
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Legal Events

Date Code Title Description
MM9K Patent not in force due to non-payment of renewal fees