NO165343C - Analogifremgangsmaate til fremstilling av nye, terapeutiskaktive 3-(2-aminoetyl)indoler. - Google Patents

Analogifremgangsmaate til fremstilling av nye, terapeutiskaktive 3-(2-aminoetyl)indoler.

Info

Publication number
NO165343C
NO165343C NO853036A NO853036A NO165343C NO 165343 C NO165343 C NO 165343C NO 853036 A NO853036 A NO 853036A NO 853036 A NO853036 A NO 853036A NO 165343 C NO165343 C NO 165343C
Authority
NO
Norway
Prior art keywords
lower alkyl
phenyl
indoles
aminoethyl
preparation
Prior art date
Application number
NO853036A
Other languages
English (en)
Norwegian (no)
Other versions
NO165343B (no
NO853036L (no
Inventor
Thomas Glaser
Siegfried Raddatz
Joerg Traber
Allen George
Original Assignee
Troponwerke Gmbh & Co Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Troponwerke Gmbh & Co Kg filed Critical Troponwerke Gmbh & Co Kg
Publication of NO853036L publication Critical patent/NO853036L/no
Publication of NO165343B publication Critical patent/NO165343B/no
Publication of NO165343C publication Critical patent/NO165343C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C07D209/16—Tryptamines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Saccharide Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Indole Compounds (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
NO853036A 1984-08-17 1985-07-31 Analogifremgangsmaate til fremstilling av nye, terapeutiskaktive 3-(2-aminoetyl)indoler. NO165343C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19843430284 DE3430284A1 (de) 1984-08-17 1984-08-17 Neue tryptamin-derivate, ein verfahren zu ihrer herstellung und ihre verwendung

Publications (3)

Publication Number Publication Date
NO853036L NO853036L (no) 1986-02-18
NO165343B NO165343B (no) 1990-10-22
NO165343C true NO165343C (no) 1991-01-30

Family

ID=6243280

Family Applications (1)

Application Number Title Priority Date Filing Date
NO853036A NO165343C (no) 1984-08-17 1985-07-31 Analogifremgangsmaate til fremstilling av nye, terapeutiskaktive 3-(2-aminoetyl)indoler.

Country Status (19)

Country Link
US (1) US4870085A (hu)
EP (1) EP0171728B1 (hu)
JP (1) JPS6169774A (hu)
KR (1) KR910006637B1 (hu)
CN (1) CN85101761A (hu)
AT (1) ATE41930T1 (hu)
AU (1) AU580321B2 (hu)
DE (2) DE3430284A1 (hu)
DK (1) DK374085A (hu)
ES (1) ES8801824A1 (hu)
FI (1) FI853134L (hu)
GR (1) GR851986B (hu)
HU (1) HU195208B (hu)
IL (1) IL76088A (hu)
NO (1) NO165343C (hu)
NZ (1) NZ213104A (hu)
PH (1) PH21048A (hu)
PT (1) PT80954B (hu)
ZA (1) ZA856227B (hu)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4808581A (en) * 1986-03-17 1989-02-28 Glaxo Group Limited Imidazolyl- indolylpropanones as 5-HT3 receptor antagonists
NZ219624A (en) * 1986-03-17 1988-11-29 Glaxo Group Ltd Indole derivatives and pharmaceutical compositions
US5162375A (en) * 1988-05-06 1992-11-10 Beecham Group P.L.C. Treatment of neuronal degeneration with 5HT1A agonists
GB8810748D0 (en) * 1988-05-06 1988-06-08 Beecham Wuelfing Gmbh & Co Kg Novel treatment
GB8819024D0 (en) * 1988-08-10 1988-09-14 Glaxo Group Ltd Chemical compounds
AU646871B2 (en) * 1990-06-07 1994-03-10 Astrazeneca Uk Limited Therapeutic heterocyclic compounds
US5317103A (en) * 1991-01-15 1994-05-31 Merck Sharp & Dohme Limited Indole-substituted five-membered heteroaromatic compounds as 5-HT1 agonists
SK278998B6 (sk) * 1991-02-01 1998-05-06 Merck Sharp & Dohme Limited Deriváty imidazolu, triazolu a tetrazolu, spôsob i
IL106445A (en) * 1992-07-30 1998-01-04 Merck Sharp & Dohme History of 1,2,4-Trans-Triazole 4-Transform, Preparation and Pharmaceutical Preparations Containing Them
DK139593D0 (da) * 1993-12-16 1993-12-16 Lundbeck & Co As H Compounds
US5854268A (en) * 1994-08-02 1998-12-29 Merck Sharp & Dohme, Ltd. Azetidine, pyrrolidine and piperidine derivatives
FR2733984B1 (fr) * 1995-05-10 1997-07-04 Rhone Poulenc Rorer Sa Derives de tryptamine, leur preparation et les medicaments les contenant
US5856510A (en) * 1996-12-16 1999-01-05 Allelix Biopharmaceuticals Inc. 5-alkenyl and 5-alkynyl indole compounds
US5998462A (en) * 1996-12-16 1999-12-07 Allelix Biopharmaceuticals Inc. 5-alkyl indole compounds
US6100291A (en) * 1998-03-16 2000-08-08 Allelix Biopharmaceuticals Inc. Pyrrolidine-indole compounds having 5-HT6 affinity
US6133287A (en) * 1998-03-24 2000-10-17 Allelix Biopharmaceuticals Inc. Piperidine-indole compounds having 5-HT6 affinity
CA2356638A1 (en) * 1998-12-23 2000-07-06 Nps Allelix Corp. Indole and indolizidine derivatives for the treatment of migraine
RU2269523C2 (ru) * 2000-04-28 2006-02-10 Акадиа Фармасьютикалз, Инк. Мускариновые агонисты
CN103183629A (zh) * 2013-03-15 2013-07-03 张家港威胜生物医药有限公司 一种重要医药化工中间体5-溴吲哚高效合成工艺
CN104292145A (zh) * 2014-10-12 2015-01-21 湖南华腾制药有限公司 一种6-溴吲哚衍生物的制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3183235A (en) * 1961-06-27 1965-05-11 Sterling Drug Inc 1-[3-, 2-, and 1-indolyl-lower-alkanoyl] piperidines
US3821387A (en) * 1965-10-23 1974-06-28 Robins Co Inc A H The treatment of parkinsonism with 3-(omega-substituted alkyl)-indoles
US3907812A (en) * 1969-07-16 1975-09-23 Sumitomo Chemical Co Butyrophenone derivatives
US3732248A (en) * 1969-12-15 1973-05-08 Pfizer 3-substituted-1-phenyl indolinones
BE795457A (fr) * 1972-02-16 1973-08-16 Clin Midy Amines indoliques, leur preparation et leur application en therapeutiques
FR2506310A1 (fr) * 1981-05-22 1982-11-26 Pharmindustrie ((alkyl- et alcenyl-3 piperidyl-4)-2 ethyl)-3 indoles et leur utilisation comme medicaments
FR2506309A1 (fr) * 1981-05-22 1982-11-26 Pharmindustrie ((tetra- et hexahydro pyridyl-4)-2 ethyl)-3 indoles et leur utilisation comme medicaments

Also Published As

Publication number Publication date
NZ213104A (en) 1988-07-28
PT80954B (pt) 1987-12-30
HU195208B (en) 1988-04-28
EP0171728A1 (de) 1986-02-19
NO165343B (no) 1990-10-22
ZA856227B (en) 1986-04-30
ATE41930T1 (de) 1989-04-15
NO853036L (no) 1986-02-18
JPS6169774A (ja) 1986-04-10
GR851986B (hu) 1985-12-10
EP0171728B1 (de) 1989-04-05
US4870085A (en) 1989-09-26
DE3569242D1 (en) 1989-05-11
DE3430284A1 (de) 1986-02-27
ES546091A0 (es) 1988-02-16
FI853134L (fi) 1986-02-18
KR870002124A (ko) 1987-03-30
HUT39443A (en) 1986-09-29
AU580321B2 (en) 1989-01-12
KR910006637B1 (ko) 1991-08-29
CN85101761A (zh) 1987-02-04
PH21048A (en) 1987-07-03
IL76088A (en) 1990-03-19
PT80954A (de) 1985-09-01
DK374085D0 (da) 1985-08-16
ES8801824A1 (es) 1988-02-16
DK374085A (da) 1986-02-18
FI853134A0 (fi) 1985-08-15
AU4597185A (en) 1986-02-20
IL76088A0 (en) 1985-12-31

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