NO164593C - Analogifremgangsmaate for fremstilling av terapeutisk aktive karbamat- eller urea-derivater. - Google Patents
Analogifremgangsmaate for fremstilling av terapeutisk aktive karbamat- eller urea-derivater.Info
- Publication number
- NO164593C NO164593C NO872832A NO872832A NO164593C NO 164593 C NO164593 C NO 164593C NO 872832 A NO872832 A NO 872832A NO 872832 A NO872832 A NO 872832A NO 164593 C NO164593 C NO 164593C
- Authority
- NO
- Norway
- Prior art keywords
- group
- halogen atoms
- methyl
- preparation
- alkyl
- Prior art date
Links
- KXDHJXZQYSOELW-UHFFFAOYSA-M Carbamate Chemical compound NC([O-])=O KXDHJXZQYSOELW-UHFFFAOYSA-M 0.000 title abstract 2
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical class NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 title 1
- 230000001225 therapeutic effect Effects 0.000 title 1
- 125000005843 halogen group Chemical group 0.000 abstract 3
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 3
- -1 methylenedioxy group Chemical group 0.000 abstract 3
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 3
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 150000002431 hydrogen Chemical group 0.000 abstract 2
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 1
- 125000004209 (C1-C8) alkyl group Chemical group 0.000 abstract 1
- 229940127291 Calcium channel antagonist Drugs 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical group [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 125000005605 benzo group Chemical group 0.000 abstract 1
- 239000000480 calcium channel blocker Substances 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 1
- 125000004186 cyclopropylmethyl group Chemical group [H]C([H])(*)C1([H])C([H])([H])C1([H])[H] 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical group 0.000 abstract 1
- 125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 abstract 1
- 125000001160 methoxycarbonyl group Chemical group [H]C([H])([H])OC(*)=O 0.000 abstract 1
- 125000002816 methylsulfanyl group Chemical group [H]C([H])([H])S[*] 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
- 150000003672 ureas Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
- C07C323/39—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton at least one of the nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom
- C07C323/40—Y being a hydrogen or a carbon atom
- C07C323/41—Y being a hydrogen or an acyclic carbon atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/27—Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
- A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
- C07C319/14—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides
- C07C319/20—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides by reactions not involving the formation of sulfide groups
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Diabetes (AREA)
- Emergency Medicine (AREA)
- Rheumatology (AREA)
- Endocrinology (AREA)
- Epidemiology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8609887A FR2601363B1 (fr) | 1986-07-08 | 1986-07-08 | (dimethylamino)-2 ethyl) ((((methylthio)-2 phenyl) (phenylmethyl)amino)-2 oxo-2 ethyl) carbamates ou urees, leur preparation et leur application en therapeutique. |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| NO872832D0 NO872832D0 (no) | 1987-07-07 |
| NO872832L NO872832L (no) | 1988-01-11 |
| NO164593B NO164593B (no) | 1990-07-16 |
| NO164593C true NO164593C (no) | 1990-10-24 |
Family
ID=9337176
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO872832A NO164593C (no) | 1986-07-08 | 1987-07-07 | Analogifremgangsmaate for fremstilling av terapeutisk aktive karbamat- eller urea-derivater. |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US4840967A (cs) |
| EP (1) | EP0252810B1 (cs) |
| JP (1) | JPS6323856A (cs) |
| KR (1) | KR880001587A (cs) |
| AT (1) | ATE62669T1 (cs) |
| AU (1) | AU595340B2 (cs) |
| CA (1) | CA1277330C (cs) |
| CS (1) | CS357891A3 (cs) |
| DE (1) | DE3769384D1 (cs) |
| DK (1) | DK349287A (cs) |
| FI (1) | FI85583C (cs) |
| FR (1) | FR2601363B1 (cs) |
| GR (1) | GR3002081T3 (cs) |
| HU (1) | HU196169B (cs) |
| IL (1) | IL83092A (cs) |
| NO (1) | NO164593C (cs) |
| NZ (1) | NZ220987A (cs) |
| PT (1) | PT85280B (cs) |
| ZA (1) | ZA874945B (cs) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2641279B1 (fr) * | 1989-01-03 | 1991-02-22 | Synthelabo | Derives de n-(amino-2 ethyl) n-(((methylthio-2 phenyl) (phenylmethyl)amino)-2 oxo ethyl)amides et carbamates, leur preparation et leur application en therapeutique |
| JPH02290464A (ja) * | 1989-04-28 | 1990-11-30 | Takagi Ind Co Ltd | 瞬間湯沸器 |
| EP0903341A1 (en) * | 1997-07-22 | 1999-03-24 | Akzo Nobel N.V. | "Novel ortho-mercaptoaniline compounds" |
| CA2284864A1 (en) | 1998-01-21 | 1999-07-29 | Zymogenetics, Inc. | Dialkyl ureas as calcitonin mimetics |
| WO2003055847A1 (en) * | 2001-12-27 | 2003-07-10 | Taisho Pharmaceutical Co.,Ltd. | Carboxylic acid derivative |
| FR2885129B1 (fr) * | 2005-04-29 | 2007-06-15 | Proskelia Sas | Nouveaux derives de l'ureee substituee parun thiazole ou benzothiazole, leur procede de preparation, leur application a titre de medicaments, les compositions pharmaceutiques les renfermant et utilisation. |
| MX2009006233A (es) * | 2006-12-11 | 2009-06-22 | Wyeth Corp | Moduladores del canal de ion. |
| AU2009282525A1 (en) * | 2008-08-13 | 2010-02-18 | Wntresearch Ab | The use of Wnt5-a peptide derivates for the treatment of melanoma and gastric cancer |
| EP2726880B1 (en) | 2011-07-01 | 2019-04-17 | Wntresearch AB | Treatment of prostate cancer and a method for determining the prognosis for prostate cancer patients |
| CA2955569C (en) | 2014-08-06 | 2023-02-14 | Ascendis Pharma A/S | Prodrugs comprising an aminoalkyl glycine linker |
-
1986
- 1986-07-08 FR FR8609887A patent/FR2601363B1/fr not_active Expired
-
1987
- 1987-07-01 AT AT87401523T patent/ATE62669T1/de not_active IP Right Cessation
- 1987-07-01 DE DE8787401523T patent/DE3769384D1/de not_active Expired - Fee Related
- 1987-07-01 EP EP87401523A patent/EP0252810B1/fr not_active Expired - Lifetime
- 1987-07-06 IL IL83092A patent/IL83092A/xx unknown
- 1987-07-07 ZA ZA874945A patent/ZA874945B/xx unknown
- 1987-07-07 PT PT85280A patent/PT85280B/pt not_active IP Right Cessation
- 1987-07-07 DK DK349287A patent/DK349287A/da not_active Application Discontinuation
- 1987-07-07 NO NO872832A patent/NO164593C/no unknown
- 1987-07-07 CA CA000541475A patent/CA1277330C/en not_active Expired - Fee Related
- 1987-07-07 AU AU75294/87A patent/AU595340B2/en not_active Ceased
- 1987-07-07 FI FI873009A patent/FI85583C/fi not_active IP Right Cessation
- 1987-07-07 US US07/070,580 patent/US4840967A/en not_active Expired - Fee Related
- 1987-07-07 HU HU873054A patent/HU196169B/hu unknown
- 1987-07-07 KR KR1019870007251A patent/KR880001587A/ko not_active Withdrawn
- 1987-07-07 NZ NZ220987A patent/NZ220987A/xx unknown
- 1987-07-07 JP JP62169610A patent/JPS6323856A/ja active Pending
-
1991
- 1991-06-06 GR GR91400752T patent/GR3002081T3/el unknown
- 1991-11-25 CS CS913578A patent/CS357891A3/cs unknown
Also Published As
| Publication number | Publication date |
|---|---|
| FR2601363A1 (fr) | 1988-01-15 |
| CA1277330C (en) | 1990-12-04 |
| NO872832L (no) | 1988-01-11 |
| KR880001587A (ko) | 1988-04-25 |
| EP0252810B1 (fr) | 1991-04-17 |
| EP0252810A2 (fr) | 1988-01-13 |
| FR2601363B1 (fr) | 1988-10-21 |
| IL83092A (en) | 1991-11-21 |
| FI873009A7 (fi) | 1988-01-09 |
| CS357891A3 (en) | 1992-12-16 |
| FI85583C (fi) | 1992-05-11 |
| AU595340B2 (en) | 1990-03-29 |
| HU196169B (en) | 1988-10-28 |
| GR3002081T3 (en) | 1992-12-30 |
| FI873009A0 (fi) | 1987-07-07 |
| US4840967A (en) | 1989-06-20 |
| NO872832D0 (no) | 1987-07-07 |
| IL83092A0 (en) | 1987-12-31 |
| ATE62669T1 (de) | 1991-05-15 |
| PT85280B (pt) | 1990-03-30 |
| JPS6323856A (ja) | 1988-02-01 |
| PT85280A (fr) | 1987-08-01 |
| NO164593B (no) | 1990-07-16 |
| NZ220987A (en) | 1989-12-21 |
| ZA874945B (en) | 1988-02-24 |
| DK349287A (da) | 1988-01-09 |
| DE3769384D1 (de) | 1991-05-23 |
| EP0252810A3 (en) | 1988-09-07 |
| DK349287D0 (da) | 1987-07-07 |
| HUT44482A (en) | 1988-03-28 |
| AU7529487A (en) | 1988-01-14 |
| FI85583B (fi) | 1992-01-31 |
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