NO164351C - Analogifremgangsmaate for fremstilling av terapeutisk aktive 5-alkyl-l-fenyl-2-piperazinoalkylpyrazolin-3-on-forbindelser. - Google Patents

Analogifremgangsmaate for fremstilling av terapeutisk aktive 5-alkyl-l-fenyl-2-piperazinoalkylpyrazolin-3-on-forbindelser.

Info

Publication number
NO164351C
NO164351C NO854677A NO854677A NO164351C NO 164351 C NO164351 C NO 164351C NO 854677 A NO854677 A NO 854677A NO 854677 A NO854677 A NO 854677A NO 164351 C NO164351 C NO 164351C
Authority
NO
Norway
Prior art keywords
phenyl
compounds
preparation
alkyl
piperazinoalkylpyrazoline
Prior art date
Application number
NO854677A
Other languages
English (en)
Norwegian (no)
Other versions
NO854677L (no
NO164351B (no
Inventor
Daniel Jasserand
Marie-Odile Christen
Dominique Biard
Dimitri Yavordios
Original Assignee
Kali Chemie Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kali Chemie Pharma Gmbh filed Critical Kali Chemie Pharma Gmbh
Publication of NO854677L publication Critical patent/NO854677L/no
Publication of NO164351B publication Critical patent/NO164351B/no
Publication of NO164351C publication Critical patent/NO164351C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/18—One oxygen or sulfur atom
    • C07D231/20—One oxygen atom attached in position 3 or 5
    • C07D231/22—One oxygen atom attached in position 3 or 5 with aryl radicals attached to ring nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Pulmonology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
NO854677A 1984-11-24 1985-11-22 Analogifremgangsmaate for fremstilling av terapeutisk aktive 5-alkyl-l-fenyl-2-piperazinoalkylpyrazolin-3-on-forbindelser. NO164351C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19843442860 DE3442860A1 (de) 1984-11-24 1984-11-24 5-alkyl-1-phenyl-2-piperazinoalkylpyrazolin-3- on-verbindungen sowie verfahren und zwischenprodukte zu ihrer herstellung und diese verbindungen enthaltende arzneimittel

Publications (3)

Publication Number Publication Date
NO854677L NO854677L (no) 1986-05-26
NO164351B NO164351B (no) 1990-06-18
NO164351C true NO164351C (no) 1990-09-26

Family

ID=6251032

Family Applications (1)

Application Number Title Priority Date Filing Date
NO854677A NO164351C (no) 1984-11-24 1985-11-22 Analogifremgangsmaate for fremstilling av terapeutisk aktive 5-alkyl-l-fenyl-2-piperazinoalkylpyrazolin-3-on-forbindelser.

Country Status (18)

Country Link
US (1) US4672063A (es)
EP (1) EP0185909B1 (es)
JP (1) JPS61148164A (es)
AT (1) ATE50448T1 (es)
AU (1) AU578395B2 (es)
CA (1) CA1247101A (es)
DD (1) DD239793A5 (es)
DE (2) DE3442860A1 (es)
DK (1) DK540585A (es)
ES (3) ES8700253A1 (es)
FI (1) FI854603A (es)
GR (1) GR852813B (es)
HU (1) HU195211B (es)
IL (1) IL77124A (es)
NO (1) NO164351C (es)
NZ (1) NZ214289A (es)
PT (1) PT81545B (es)
ZA (1) ZA858418B (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1279645C (en) * 1986-02-27 1991-01-29 Ineke Van Wijngaarden Aryl-substituted (n-piperidinyl)methyl- and (n-piperazinyl)methylazoles having antipsychotic properties
FR2648135B1 (fr) * 1989-06-07 1991-09-27 Pf Medicament Derives de phenyl-1-dihydro-1,4 amino-3 oxo-4 pyridazines, leur preparation et leur application en therapeutique
FR2676733B1 (fr) * 1991-05-22 1993-10-01 Fabre Medicament Pierre Derives de phenyl-1 dihydro-1,4 hydroxy-3 oxo-4 pyridazines, leur preparation et leur application en therapeutique.
US5219856A (en) * 1992-04-06 1993-06-15 E. I. Du Pont De Nemours And Company Angiotensin-II receptor blocking, heterocycle substituted imidazoles
US7842693B2 (en) * 2002-06-12 2010-11-30 Chemocentryx, Inc. Substituted piperazines
US20050256130A1 (en) * 2002-06-12 2005-11-17 Chemocentryx, Inc. Substituted piperazines
CN1867336B (zh) 2002-06-12 2010-05-12 凯莫森特里克斯股份有限公司 1-芳基-4-取代的哌嗪衍生物及其制药用途
US7589199B2 (en) * 2002-06-12 2009-09-15 Chemocentryx, Inc. Substituted piperazines
EP1720545B1 (en) * 2004-03-03 2014-10-29 ChemoCentryx, Inc. Bicyclic and bridged nitrogen heterocycles
US7435831B2 (en) * 2004-03-03 2008-10-14 Chemocentryx, Inc. Bicyclic and bridged nitrogen heterocycles
ES2462240T3 (es) 2006-02-28 2014-05-22 Dart Neuroscience (Cayman) Ltd Piperazinas terapéuticas como inhibidores de PDE4
US8927546B2 (en) * 2006-02-28 2015-01-06 Dart Neuroscience (Cayman) Ltd. Therapeutic piperazines
JP2008148592A (ja) * 2006-12-15 2008-07-03 Sk Sangyo Kk 防風網

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3169966A (en) * 1961-01-24 1965-02-16 Ciba Geigy Corp Aminopyrazoles
US3362956A (en) * 1965-08-19 1968-01-09 Sterling Drug Inc 1-[(heterocyclyl)-lower-alkyl]-4-substituted-piperazines
IT1052130B (it) * 1973-10-15 1981-06-20 Sigma Tau Ind Farmaceuti Derivati del triazolinone e procedimento per la loro preparazione
DE3132916A1 (de) * 1981-08-20 1983-03-03 Kali-Chemie Pharma Gmbh, 3000 Hannover 1-phenylindazol-3-on-verbindungen sowie verfahren und zwischenprodukte zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3132915A1 (de) * 1981-08-20 1983-03-03 Kali-Chemie Pharma Gmbh, 3000 Hannover 1,5-diphenylpyrazolin-3-on-verbindungen sowie verfahren und zwischenprodukte zu ihrer herstellung und diese verbindungen enthaltende arzneimittel

Also Published As

Publication number Publication date
ES555006A0 (es) 1987-03-01
EP0185909B1 (de) 1990-02-21
IL77124A (en) 1990-03-19
DE3576075D1 (de) 1990-03-29
ES8703869A1 (es) 1987-03-01
DK540585A (da) 1986-05-25
DK540585D0 (da) 1985-11-22
JPS61148164A (ja) 1986-07-05
ES549176A0 (es) 1986-10-01
HUT38927A (en) 1986-07-28
PT81545B (pt) 1988-01-22
GR852813B (es) 1986-03-21
AU578395B2 (en) 1988-10-20
NO854677L (no) 1986-05-26
AU5035085A (en) 1986-07-17
CA1247101A (en) 1988-12-20
HU195211B (en) 1988-04-28
EP0185909A1 (de) 1986-07-02
ES8700253A1 (es) 1986-10-01
DD239793A5 (de) 1986-10-08
NZ214289A (en) 1988-10-28
ATE50448T1 (de) 1990-03-15
US4672063A (en) 1987-06-09
ES555007A0 (es) 1987-03-01
ZA858418B (en) 1986-07-30
PT81545A (en) 1985-12-01
ES8703870A1 (es) 1987-03-01
NO164351B (no) 1990-06-18
FI854603A (fi) 1986-05-25
IL77124A0 (en) 1986-04-29
DE3442860A1 (de) 1986-05-28
FI854603A0 (fi) 1985-11-21

Similar Documents

Publication Publication Date Title
HUT38210A (en) Insecticidal, miticidal and nematocidal compositions comprising nitromethylene derivatives as active substance and process for producing the active substances
NO892058D0 (no) Fremgangsnaate for fremstilling av terapeutisk aktive benzamider.
NO164351C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive 5-alkyl-l-fenyl-2-piperazinoalkylpyrazolin-3-on-forbindelser.
EG14365A (en) Derives de l'imidazole et medicaments qui en contiennent
ES481551A1 (es) Procedimiento de preparacion de nuevos compuestos bis (ari- loxicarboxilicos).
MX170732B (es) Composicion de derivados de succinimida y su uso
ATE16010T1 (de) Neue hydrocortison-derivate, ihre herstellung und verwendung.
SE8006953L (sv) Heterocykliska foreningar
DK384485D0 (da) 1,6-naphthyridinderivater med kardilaterende virkning
ES8400743A1 (es) "procedimiento para la preparacion de compuestos de 1-fenilindazol-3-ona".
SE8008189L (sv) Foreningar med antiallergisk och antiulceros verkan, nemligen 1-oxo-1h-tiazolo(3,2-a)pyrimidin-2-karboxamider och mellanprodukter for dessa
JPS5414956A (en) Novel 3-amino-4-homoisotwistan derivative
ES523797A0 (es) Procedimiento para la obtencion de b-lactamantibioticos.
AU551901B2 (en) Substituted thienobenzodiazepinones
FI824479L (fi) Foerfarande och mellanprodukt foer framstaellning av farmakologiskt verksamma (1,2)-anellerade 1,4-bensodiazepinfoereningar
IE42053L (en) Phosphorus thiazole derivatives
SE7706693L (sv) Sett att framstella hydrazinopyridazinderivat
SE7909980L (sv) I-amino-indolin-derivat, deras framstellning och farmaceutiska kompositioner innehallande desamma