NO159929C - Analogifremgangsmaate til fremstilling av terapeutisk aktive n-substituerte 2-pyridylindoler. - Google Patents

Analogifremgangsmaate til fremstilling av terapeutisk aktive n-substituerte 2-pyridylindoler.

Info

Publication number
NO159929C
NO159929C NO823869A NO823869A NO159929C NO 159929 C NO159929 C NO 159929C NO 823869 A NO823869 A NO 823869A NO 823869 A NO823869 A NO 823869A NO 159929 C NO159929 C NO 159929C
Authority
NO
Norway
Prior art keywords
substituted
preparation
therapeutically active
analogue procedure
pyridyl indoles
Prior art date
Application number
NO823869A
Other languages
English (en)
Norwegian (no)
Other versions
NO823869L (no
NO159929B (no
Inventor
Harris Burt Renfroe
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of NO823869L publication Critical patent/NO823869L/no
Publication of NO159929B publication Critical patent/NO159929B/no
Publication of NO159929C publication Critical patent/NO159929C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C243/00—Compounds containing chains of nitrogen atoms singly-bound to each other, e.g. hydrazines, triazanes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
NO823869A 1981-11-19 1982-11-18 Analogifremgangsmaate til fremstilling av terapeutisk aktive n-substituerte 2-pyridylindoler. NO159929C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US32301881A 1981-11-19 1981-11-19

Publications (3)

Publication Number Publication Date
NO823869L NO823869L (no) 1983-05-20
NO159929B NO159929B (no) 1988-11-14
NO159929C true NO159929C (no) 1989-02-22

Family

ID=23257445

Family Applications (1)

Application Number Title Priority Date Filing Date
NO823869A NO159929C (no) 1981-11-19 1982-11-18 Analogifremgangsmaate til fremstilling av terapeutisk aktive n-substituerte 2-pyridylindoler.

Country Status (22)

Country Link
EP (1) EP0080154B1 (ko)
JP (1) JPS5892677A (ko)
KR (1) KR880002010B1 (ko)
AR (3) AR241428A1 (ko)
AT (1) ATE15196T1 (ko)
AU (1) AU564233B2 (ko)
CA (1) CA1197249A (ko)
DD (1) DD204924A5 (ko)
DE (1) DE3265892D1 (ko)
DK (1) DK169104B1 (ko)
ES (4) ES8501755A1 (ko)
FI (1) FI75344C (ko)
GB (1) GB2111050B (ko)
GR (1) GR77035B (ko)
HU (1) HU190425B (ko)
IE (1) IE54156B1 (ko)
IL (1) IL67284A (ko)
NO (1) NO159929C (ko)
NZ (1) NZ202551A (ko)
PH (1) PH19212A (ko)
PT (1) PT75870B (ko)
ZA (1) ZA828505B (ko)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4511573A (en) * 1983-05-17 1985-04-16 Ciba-Geigy Corporation 3-Substituted-2-(heteroaryl) indoles
GB8524157D0 (en) * 1984-10-19 1985-11-06 Ici America Inc Heterocyclic amides
US4675332A (en) * 1984-12-10 1987-06-23 Warner-Lambert Company Acidic tetrazolyl substituted indole compounds and their use as antiallergy agents
US4609733A (en) * 1984-12-27 1986-09-02 Ciba-Geigy Corporation 3-keto-substituted-N-pyridylindoles
GB8626296D0 (en) * 1986-11-04 1986-12-03 Ici Plc Therapeutic agents
GB8626297D0 (en) * 1986-11-04 1986-12-03 Ici Plc Pharmaceutical compositions
GB9319100D0 (en) * 1993-09-15 1993-11-03 Pfizer Ltd 3-(3-pyridinyl)h-indoles
CA2140722A1 (en) * 1994-01-24 1995-07-25 Joseph A. Jakubowski Beta-carboline thromboxane synthase inhibitors
US6828344B1 (en) * 1998-02-25 2004-12-07 Genetics Institute, Llc Inhibitors of phospholipase enzymes
GB0307891D0 (en) * 2003-04-04 2003-05-14 Angeletti P Ist Richerche Bio Chemical compounds,compositions and uses
AR072297A1 (es) * 2008-06-27 2010-08-18 Novartis Ag Derivados de indol-2-il-piridin-3-ilo, composicion farmaceutica que los comprende y su uso en medicamentos para el tratamiento de enfermedades mediadas por la sintasa aldosterona.
BR112020011668A2 (pt) * 2017-12-15 2020-11-17 Bristol-Myers Squibb Company compostos de éter de indol substituído

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3468894A (en) * 1966-11-29 1969-09-23 Geigy Chem Corp Certain 2-pyridyl-substituted indole derivatives
DE2909779A1 (de) * 1979-03-13 1980-09-18 Thomae Gmbh Dr K Neue indolderivate, deren herstellung und deren verwendung als arzneimittel

Also Published As

Publication number Publication date
EP0080154B1 (de) 1985-08-28
EP0080154A3 (en) 1983-09-28
ES8608508A1 (es) 1986-06-16
IE54156B1 (en) 1989-07-05
AU564233B2 (en) 1987-08-06
PT75870B (en) 1986-01-21
ES517439A0 (es) 1984-12-01
HU190425B (en) 1986-09-29
ZA828505B (en) 1983-09-28
PT75870A (en) 1982-12-01
ES530126A0 (es) 1985-11-16
ATE15196T1 (de) 1985-09-15
DE3265892D1 (en) 1985-10-03
DD204924A5 (de) 1983-12-14
NZ202551A (en) 1985-11-08
DK514182A (da) 1983-05-20
GB2111050A (en) 1983-06-29
AR241428A1 (es) 1992-07-31
NO823869L (no) 1983-05-20
JPS5892677A (ja) 1983-06-02
CA1197249A (en) 1985-11-26
KR880002010B1 (ko) 1988-10-12
IL67284A (en) 1986-03-31
FI75344C (fi) 1988-06-09
NO159929B (no) 1988-11-14
ES8601962A1 (es) 1985-11-16
FI823938A0 (fi) 1982-11-17
PH19212A (en) 1986-02-04
ES8501755A1 (es) 1984-12-01
EP0080154A2 (de) 1983-06-01
ES530127A0 (es) 1986-06-16
AR243519A1 (es) 1993-08-31
KR840002368A (ko) 1984-06-25
GR77035B (ko) 1984-09-04
AU9067582A (en) 1983-05-26
ES530128A0 (es) 1985-12-01
FI75344B (fi) 1988-02-29
FI823938L (fi) 1983-05-20
JPH029031B2 (ko) 1990-02-28
DK169104B1 (da) 1994-08-15
GB2111050B (en) 1985-09-11
ES8602750A1 (es) 1985-12-01
AR243177A1 (es) 1993-07-30

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