NO153768C - Analogifremgangsmaate for fremstilling av 2-2(2-benzyl-3-merkapto-propionylamino)-derivater av 1-alkanoler og av 4-metyltiosmoersyre. - Google Patents
Analogifremgangsmaate for fremstilling av 2-2(2-benzyl-3-merkapto-propionylamino)-derivater av 1-alkanoler og av 4-metyltiosmoersyre.Info
- Publication number
- NO153768C NO153768C NO821595A NO821595A NO153768C NO 153768 C NO153768 C NO 153768C NO 821595 A NO821595 A NO 821595A NO 821595 A NO821595 A NO 821595A NO 153768 C NO153768 C NO 153768C
- Authority
- NO
- Norway
- Prior art keywords
- methyltyoic
- propionylamino
- alkanols
- mercapto
- benzyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
- C07C319/14—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides
- C07C319/20—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides by reactions not involving the formation of sulfide groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
- C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
- C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/60—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton with the carbon atom of at least one of the carboxyl groups bound to nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C327/00—Thiocarboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/52—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen
- C07C57/58—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/52—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen
- C07C57/58—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings
- C07C57/60—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings having unsaturation outside the rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pain & Pain Management (AREA)
- Neurology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/264,752 US4329495A (en) | 1981-05-18 | 1981-05-18 | Enkephalinase enzyme inhibiting compounds |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO821595L NO821595L (no) | 1982-11-19 |
| NO153768B NO153768B (no) | 1986-02-10 |
| NO153768C true NO153768C (no) | 1986-05-21 |
Family
ID=23007448
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO821595A NO153768C (no) | 1981-05-18 | 1982-05-13 | Analogifremgangsmaate for fremstilling av 2-2(2-benzyl-3-merkapto-propionylamino)-derivater av 1-alkanoler og av 4-metyltiosmoersyre. |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US4329495A (no) |
| EP (1) | EP0066956B1 (no) |
| JP (1) | JPS57193450A (no) |
| KR (1) | KR860001549B1 (no) |
| AR (1) | AR231279A1 (no) |
| AT (1) | ATE8881T1 (no) |
| AU (1) | AU529511B2 (no) |
| CA (1) | CA1179368A (no) |
| DE (1) | DE3260531D1 (no) |
| DK (1) | DK160711B (no) |
| ES (2) | ES512278A0 (no) |
| FI (1) | FI76555C (no) |
| GR (1) | GR75496B (no) |
| HU (1) | HU188058B (no) |
| IE (1) | IE53226B1 (no) |
| IL (1) | IL65799A (no) |
| IN (1) | IN158365B (no) |
| NO (1) | NO153768C (no) |
| NZ (1) | NZ200639A (no) |
| PH (1) | PH18206A (no) |
| PL (1) | PL138043B1 (no) |
| PT (1) | PT74913B (no) |
| YU (1) | YU42468B (no) |
| ZA (1) | ZA823386B (no) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4432972A (en) * | 1981-08-03 | 1984-02-21 | E. R. Squibb & Sons, Inc. | Phosphonamidate compounds |
| US4474799A (en) * | 1981-10-09 | 1984-10-02 | E. R. Squibb & Sons, Inc. | Enkephalinase inhibitors |
| US4474795A (en) * | 1981-10-09 | 1984-10-02 | E. R. Squibb & Sons, Inc. | Enkephalinase inhibitors |
| US4401677A (en) * | 1981-10-09 | 1983-08-30 | E. R. Squibb & Sons, Inc. | Enkephalinase inhibitors |
| JPS58140065A (ja) * | 1982-02-10 | 1983-08-19 | Meito Sangyo Kk | メルカプトベンジル脂肪酸誘導体類及びその製法 |
| FR2540495B1 (fr) * | 1983-02-07 | 1986-02-14 | Roussel Uclaf | Nouveaux derives de o-mercaptopropanamide et de ses homologues, leur procede de preparation, leur application comme medicaments, les compositions les renfermant et les nouveaux intermediaires obtenus |
| FR2540498B1 (fr) * | 1983-02-07 | 1986-02-14 | Roussel Uclaf | Nouveaux medicaments derives d'amides d'acide mercaptoacetique et de l'acide 3-mercaptopropionique et les compositions pharmaceutiques les renfermant |
| FR2556721B1 (fr) * | 1983-12-14 | 1986-05-16 | Roussel Uclaf | Nouveaux derives de o-mercaptopropanamide d'o amino-acides, leur procede de preparation, leur application comme medicaments et les compositions les renfermant |
| FR2559770B1 (fr) * | 1984-02-20 | 1986-10-24 | Roussel Uclaf | Nouveaux derives de n-alkyl-o-mercaptopropanamide, leurs procedes de preparation, leur application comme medicaments, les compositions les renfermant et les nouveaux intermediaires obtenus |
| US4801609B1 (en) * | 1987-03-27 | 1993-11-09 | Mercapto-acylamino acid antihypertensives | |
| EP0254032A3 (en) * | 1986-06-20 | 1990-09-05 | Schering Corporation | Neutral metalloendopeptidase inhibitors in the treatment of hypertension |
| US4929641B1 (en) * | 1988-05-11 | 1994-08-30 | Schering Corp | Mercapto-acylamino acid antihypertensives |
| EP0566157A1 (en) | 1986-06-20 | 1993-10-20 | Schering Corporation | Neutral metalloendopeptidase inhibitors in the treatment of hypertension |
| US5262436A (en) * | 1987-03-27 | 1993-11-16 | Schering Corporation | Acylamino acid antihypertensives in the treatment of congestive heart failure |
| WO1990002117A1 (en) * | 1988-08-24 | 1990-03-08 | Schering Corporation | Mercapto-acylamino acid antihypertensives |
| US4879309A (en) * | 1988-09-27 | 1989-11-07 | Schering Corporation | Mercapto-acylamino acids as antihypertensives |
| ZA902661B (en) * | 1989-04-10 | 1991-01-30 | Schering Corp | Mercapto-acyl amino acids |
| FR2652087B1 (fr) * | 1989-09-15 | 1993-10-15 | Bioprojet Ste Civile | Derives d'amino-acides, leur procede de preparation et leurs applications therapeutiques. |
| US5599951A (en) * | 1989-09-15 | 1997-02-04 | Societe Civile Bioprojet | Amino acid derivatives, the process for their preparation and their applications to therapy |
| WO1991009840A1 (en) * | 1989-12-22 | 1991-07-11 | Schering Corporation | Mercaptocycloacyl aminoacid endopeptidase inhibitors |
| IE911666A1 (en) * | 1990-05-17 | 1991-11-20 | Schering Corp | Disulfide derivatives of mercapto-acylamino acids |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4046889A (en) * | 1976-02-13 | 1977-09-06 | E. R. Squibb & Sons, Inc. | Azetidine-2-carboxylic acid derivatives |
| US4053651A (en) * | 1976-05-10 | 1977-10-11 | E. R. Squibb & Sons, Inc. | Compounds and method for alleviating angiotensin related hypertension |
| JPS56158746A (en) * | 1980-04-11 | 1981-12-07 | Wellcome Found | Pharmaceutical amide |
| FR2480747A1 (fr) * | 1980-04-17 | 1981-10-23 | Roques Bernard | Derives d'acides amines et leur application therapeutique |
-
1981
- 1981-05-18 US US06/264,752 patent/US4329495A/en not_active Expired - Lifetime
-
1982
- 1982-03-30 IN IN263/DEL/82A patent/IN158365B/en unknown
- 1982-05-11 DE DE8282302387T patent/DE3260531D1/de not_active Expired
- 1982-05-11 AT AT82302387T patent/ATE8881T1/de active
- 1982-05-11 EP EP82302387A patent/EP0066956B1/en not_active Expired
- 1982-05-13 GR GR68139A patent/GR75496B/el unknown
- 1982-05-13 NO NO821595A patent/NO153768C/no unknown
- 1982-05-13 HU HU821506A patent/HU188058B/hu not_active IP Right Cessation
- 1982-05-14 PL PL1982236425A patent/PL138043B1/pl unknown
- 1982-05-14 AR AR289397A patent/AR231279A1/es active
- 1982-05-14 PH PH27313A patent/PH18206A/en unknown
- 1982-05-14 CA CA000402956A patent/CA1179368A/en not_active Expired
- 1982-05-17 JP JP57082977A patent/JPS57193450A/ja active Granted
- 1982-05-17 FI FI821736A patent/FI76555C/fi not_active IP Right Cessation
- 1982-05-17 IL IL65799A patent/IL65799A/xx unknown
- 1982-05-17 ZA ZA823386A patent/ZA823386B/xx unknown
- 1982-05-17 ES ES512278A patent/ES512278A0/es active Granted
- 1982-05-17 KR KR8202139A patent/KR860001549B1/ko active
- 1982-05-17 YU YU1042/82A patent/YU42468B/xx unknown
- 1982-05-17 NZ NZ200639A patent/NZ200639A/en unknown
- 1982-05-17 AU AU83759/82A patent/AU529511B2/en not_active Ceased
- 1982-05-17 DK DK221182A patent/DK160711B/da not_active Application Discontinuation
- 1982-05-17 IE IE1168/82A patent/IE53226B1/en unknown
- 1982-05-17 PT PT74913A patent/PT74913B/pt unknown
-
1983
- 1983-02-09 ES ES519668A patent/ES519668A0/es active Granted
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