NO146538C - Analogifremgangsmaate for fremstilling av fysiologisk aktive n-substituerte prostaglandinkarboksamider - Google Patents

Analogifremgangsmaate for fremstilling av fysiologisk aktive n-substituerte prostaglandinkarboksamider

Info

Publication number
NO146538C
NO146538C NO2379/73A NO237973A NO146538C NO 146538 C NO146538 C NO 146538C NO 2379/73 A NO2379/73 A NO 2379/73A NO 237973 A NO237973 A NO 237973A NO 146538 C NO146538 C NO 146538C
Authority
NO
Norway
Prior art keywords
carboxamids
prostaglandine
substituted
preparation
physiologically active
Prior art date
Application number
NO2379/73A
Other languages
English (en)
Norwegian (no)
Other versions
NO146538B (no
Inventor
Thomas Ken Schaaf
Hans-Jurgen Ernst Hess
Leonard Joseph Czuba
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Priority to NO752272A priority Critical patent/NO146773C/no
Publication of NO146538B publication Critical patent/NO146538B/no
Publication of NO146538C publication Critical patent/NO146538C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0041—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing nitrogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/10—Oxygen atoms
    • C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/30—Hetero atoms other than halogen
    • C07D333/34—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/40—Esters thereof
    • C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/4006—Esters of acyclic acids which can have further substituents on alkyl
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/54—Quaternary phosphonium compounds
    • C07F9/5407—Acyclic saturated phosphonium compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Furan Compounds (AREA)
  • Pyrane Compounds (AREA)
NO2379/73A 1972-06-07 1973-06-06 Analogifremgangsmaate for fremstilling av fysiologisk aktive n-substituerte prostaglandinkarboksamider NO146538C (no)

Priority Applications (1)

Application Number Priority Date Filing Date Title
NO752272A NO146773C (no) 1972-06-07 1975-06-25 Utgangsforbindelse for fremstilling av n-substituerte prostaglandin-karboksamider

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US26051872A 1972-06-07 1972-06-07

Publications (2)

Publication Number Publication Date
NO146538B NO146538B (no) 1982-07-12
NO146538C true NO146538C (no) 1982-10-20

Family

ID=22989486

Family Applications (2)

Application Number Title Priority Date Filing Date
NO2379/73A NO146538C (no) 1972-06-07 1973-06-06 Analogifremgangsmaate for fremstilling av fysiologisk aktive n-substituerte prostaglandinkarboksamider
NO740850A NO142784C (no) 1972-06-07 1974-03-11 Forbindelse for fremstilling av n-substituerte prostaglandin-karboksamider

Family Applications After (1)

Application Number Title Priority Date Filing Date
NO740850A NO142784C (no) 1972-06-07 1974-03-11 Forbindelse for fremstilling av n-substituerte prostaglandin-karboksamider

Country Status (24)

Country Link
JP (2) JPS5715591B2 (OSRAM)
AR (1) AR207434A1 (OSRAM)
AT (1) AT340069B (OSRAM)
BE (1) BE800580A (OSRAM)
CA (1) CA985280A (OSRAM)
CH (3) CH591511A5 (OSRAM)
CS (1) CS200166B2 (OSRAM)
DD (2) DD115687A5 (OSRAM)
DE (1) DE2329092A1 (OSRAM)
ES (3) ES415611A1 (OSRAM)
FI (1) FI58327C (OSRAM)
FR (2) FR2187344B1 (OSRAM)
GB (2) GB1439512A (OSRAM)
HU (3) HU170487B (OSRAM)
IE (1) IE38058B1 (OSRAM)
IL (2) IL42385A (OSRAM)
IN (1) IN138966B (OSRAM)
LU (1) LU67754A1 (OSRAM)
NL (2) NL160814C (OSRAM)
NO (2) NO146538C (OSRAM)
PH (2) PH14204A (OSRAM)
SE (3) SE415883B (OSRAM)
YU (1) YU36498B (OSRAM)
ZA (1) ZA733763B (OSRAM)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX3291E (es) * 1975-04-23 1980-08-22 Upjohn Co Procedimiento para preparar analogos de prostaglandinas
US6395787B1 (en) 2000-02-08 2002-05-28 Allergan Sales, Inc. Ocular hypotensive lipids
US6476064B1 (en) * 2001-06-13 2002-11-05 Allergan, Inc. Cyclopentane heptan(ene) acyl sulfonamide, 2-alkyl or 2-arylalkyl, or 2-heteroarylalkenyl derivatives as therapeutic agents

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3187043A (en) * 1962-05-18 1965-06-01 Monsanto Co Monohalophosphonium halides

Also Published As

Publication number Publication date
LU67754A1 (OSRAM) 1973-12-14
IE38058B1 (en) 1977-12-21
NL160814B (nl) 1979-07-16
HU170200B (OSRAM) 1977-04-28
IN138966B (OSRAM) 1976-04-17
HU170487B (OSRAM) 1977-06-28
NO146538B (no) 1982-07-12
DD109211A5 (OSRAM) 1974-10-20
FR2273814A1 (fr) 1976-01-02
HU170491B (OSRAM) 1977-06-28
YU36498B (en) 1984-02-29
NO142784C (no) 1980-10-15
FR2273814B1 (OSRAM) 1977-07-08
SE418744B (sv) 1981-06-22
AT340069B (de) 1977-11-25
SE7608225L (sv) 1976-07-19
FI58327B (fi) 1980-09-30
NL7307867A (OSRAM) 1973-12-11
JPS5715591B2 (OSRAM) 1982-03-31
DE2329092A1 (de) 1974-01-03
IL42385A (en) 1979-10-31
AR207434A1 (es) 1976-10-08
IE38058L (en) 1973-12-07
NO740850L (no) 1973-12-10
YU152673A (en) 1982-02-25
PH13092A (en) 1979-11-27
SE7608224L (sv) 1976-07-19
CH591511A5 (OSRAM) 1977-09-30
CH605887A5 (OSRAM) 1978-10-13
PH14204A (en) 1981-04-01
IL51525A0 (en) 1977-04-29
SE415883B (sv) 1980-11-10
CA985280A (en) 1976-03-09
GB1439512A (en) 1976-06-16
CS200166B2 (en) 1980-08-29
BE800580A (fr) 1973-12-07
GB1439511A (en) 1976-06-16
JPS5731692A (en) 1982-02-20
ES415611A1 (es) 1976-07-16
FI58327C (fi) 1981-01-12
ES430417A1 (es) 1977-03-01
NL160814C (nl) 1979-12-17
DD115687A5 (OSRAM) 1975-10-12
FR2187344B1 (OSRAM) 1977-10-28
CH593929A5 (OSRAM) 1977-12-30
IL42385A0 (en) 1973-07-30
JPS4954350A (OSRAM) 1974-05-27
NL7812163A (nl) 1979-04-27
FR2187344A1 (OSRAM) 1974-01-18
NO142784B (no) 1980-07-07
ZA733763B (en) 1974-04-24
ES430416A1 (es) 1976-10-16
AU5643173A (en) 1974-12-05
ATA504873A (de) 1977-03-15

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