NO146057C - Analogifremgangsmaate ved fremstilling av terapeutisk aktive aminoalkoholderivater - Google Patents

Analogifremgangsmaate ved fremstilling av terapeutisk aktive aminoalkoholderivater

Info

Publication number
NO146057C
NO146057C NO781554A NO781554A NO146057C NO 146057 C NO146057 C NO 146057C NO 781554 A NO781554 A NO 781554A NO 781554 A NO781554 A NO 781554A NO 146057 C NO146057 C NO 146057C
Authority
NO
Norway
Prior art keywords
aminoal
preparation
alcohol derivatives
therapeutic active
analogy procedure
Prior art date
Application number
NO781554A
Other languages
English (en)
Norwegian (no)
Other versions
NO781554L (no
NO146057B (no
Inventor
Georges Lambelin
Romeo Roncucci
Joseph Roba
Claude Gillet
Michel Snyers
Original Assignee
Continental Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from LU77237A external-priority patent/LU77237A1/xx
Priority claimed from LU77236A external-priority patent/LU77236A1/xx
Application filed by Continental Pharma filed Critical Continental Pharma
Publication of NO781554L publication Critical patent/NO781554L/no
Publication of NO146057B publication Critical patent/NO146057B/no
Publication of NO146057C publication Critical patent/NO146057C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C323/31—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton
    • C07C323/32—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton having at least one of the nitrogen atoms bound to an acyclic carbon atom of the carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C45/70—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form
    • C07C45/71—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form being hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/02—Systems containing only non-condensed rings with a three-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/04—Systems containing only non-condensed rings with a four-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
    • C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/36—Systems containing two condensed rings the rings having more than two atoms in common
    • C07C2602/42—Systems containing two condensed rings the rings having more than two atoms in common the bicyclo ring system containing seven carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Obesity (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
NO781554A 1977-05-03 1978-05-02 Analogifremgangsmaate ved fremstilling av terapeutisk aktive aminoalkoholderivater NO146057C (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
LU77237A LU77237A1 (da) 1977-05-03 1977-05-03
LU77236A LU77236A1 (da) 1977-05-03 1977-05-03

Publications (3)

Publication Number Publication Date
NO781554L NO781554L (no) 1978-11-06
NO146057B NO146057B (no) 1982-04-13
NO146057C true NO146057C (no) 1982-07-21

Family

ID=26640226

Family Applications (1)

Application Number Title Priority Date Filing Date
NO781554A NO146057C (no) 1977-05-03 1978-05-02 Analogifremgangsmaate ved fremstilling av terapeutisk aktive aminoalkoholderivater

Country Status (21)

Country Link
US (1) US4474977A (da)
JP (1) JPS5940140B2 (da)
AR (1) AR224499A1 (da)
AT (1) AT358020B (da)
CA (1) CA1118438A (da)
CH (1) CH635570A5 (da)
DE (1) DE2817494A1 (da)
DK (1) DK189878A (da)
ES (1) ES469843A1 (da)
FI (1) FI781347A (da)
FR (1) FR2389597B1 (da)
GR (1) GR64990B (da)
IE (1) IE47194B1 (da)
IL (1) IL54608A (da)
IT (1) IT1113140B (da)
MX (1) MX5160E (da)
NL (1) NL7804621A (da)
NO (1) NO146057C (da)
PT (1) PT67969B (da)
SE (1) SE7804897L (da)
YU (1) YU106178A (da)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0103830A3 (de) * 1982-09-22 1985-07-31 Bayer Ag Wachstumsfördernde Phenylethylamin-Derivate
CA2415678A1 (en) * 2000-07-13 2003-01-10 Sankyo Company Limited Amino alcohol derivatives
US6399828B1 (en) * 2001-10-29 2002-06-04 Boehringer Ingelheim Chemicals, Inc. Preparation of amphetamines from phenylpropanolamines
AU2003248614B2 (en) * 2002-07-17 2007-08-30 Lek Pharmaceuticals D.D. Novel derivatives of pyridylethanol (phenylethyl) amines as inhibitors of cholesterol biosynthesis, processes for their preparation, and pharmaceutical compositions containing them
US8592419B2 (en) * 2004-10-29 2013-11-26 Musc Foundation For Research Development Ceramides and apoptosis-signaling ligand
GB0624757D0 (en) * 2006-12-12 2007-01-17 Sosei R & D Ltd Novel compounds
CA2742866C (en) 2008-11-06 2017-10-24 Musc Foundation For Research Development Lysosomotropic inhibitors of acid ceramidase
CN101759665B (zh) * 2008-12-23 2012-03-28 江苏恩华药业股份有限公司 取代苯基哌嗪芳烷醇衍生物及其在制备镇痛药物中的应用

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1799110A (en) * 1928-07-21 1931-03-31 Lilly Co Eli Process of producing ephedrine and structurally-similar compounds and products of such process
NL112967C (da) 1961-05-09
DE1249881B (de) * 1962-10-18 1967-09-14 Aktiebolaget Hassle Apotekare Paul Nordstrome Fabriker Göteborg (Schweden) Verfahren zur Herstellung von Phenylathanolammen und deren Salzen
AT244932B (de) 1963-06-04 1966-02-10 Haessle Ab Verfahren zur Herstellung von neuen Phenyläthanolaminen und ihren Salzen
AT252214B (de) * 1963-10-09 1967-02-10 Bayer Ag Verfahren zur Herstellung von neuen D(-)-N-Akyl-1-phenyl-2-aminoäthanolen und/oder deren Salzen
DE1593837A1 (de) 1967-06-29 1970-10-29 Degussa Verfahren zur Herstellung von neuen Aminoketonen
US3714229A (en) * 1969-07-10 1973-01-30 Merck & Co Inc ESTERS OF 3-HYDROXY- alpha -(1-AMINOETHYL)-BENZYL ALCOHOL
GB1321701A (en) * 1969-10-01 1973-06-27 Continental Pharma Amino-alcohols their salts and process for prepairing the same
US4018825A (en) * 1972-07-27 1977-04-19 Warner-Lambert Company 5-Hydroxy-α-(substituted aminomethyl)-m-xylene-α,α'-diols
US3809714A (en) * 1972-08-31 1974-05-07 Interx Research Corp Novel ester of ((methylamino)methyl) benzyl alcohol
GB1390748A (en) * 1973-04-09 1975-04-16 Continental Pharma Alkyl and cycloalkylthiophenylalkylaminoalkanols their salts and the preparation thereof
US4009179A (en) * 1975-10-15 1977-02-22 E. I. Du Pont De Nemours And Company Di- and tri-substituted oxazolidin-2-one oximes

Also Published As

Publication number Publication date
FR2389597A1 (da) 1978-12-01
JPS5940140B2 (ja) 1984-09-28
ES469843A1 (es) 1979-09-16
US4474977A (en) 1984-10-02
DE2817494A1 (de) 1978-11-09
DK189878A (da) 1978-11-04
SE7804897L (sv) 1978-11-04
ATA317978A (de) 1980-01-15
IT7822985A0 (it) 1978-05-03
FR2389597B1 (da) 1983-08-19
PT67969B (fr) 1979-11-14
IT1113140B (it) 1986-01-20
CH635570A5 (fr) 1983-04-15
AT358020B (de) 1980-08-11
GR64990B (en) 1980-06-11
YU106178A (en) 1983-01-21
NO781554L (no) 1978-11-06
IL54608A (en) 1984-01-31
AR224499A1 (es) 1981-12-15
FI781347A (fi) 1978-11-04
IL54608A0 (en) 1978-07-31
MX5160E (es) 1983-04-11
CA1118438A (en) 1982-02-16
PT67969A (fr) 1978-05-01
NL7804621A (nl) 1978-11-07
NO146057B (no) 1982-04-13
JPS53141230A (en) 1978-12-08
IE780867L (en) 1978-11-03
IE47194B1 (en) 1984-01-11

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