NO127137B - - Google Patents
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- Publication number
- NO127137B NO127137B NO36369A NO36369A NO127137B NO 127137 B NO127137 B NO 127137B NO 36369 A NO36369 A NO 36369A NO 36369 A NO36369 A NO 36369A NO 127137 B NO127137 B NO 127137B
- Authority
- NO
- Norway
- Prior art keywords
- methylthiophenthiazine
- methylthiodiphenylamine
- melting point
- cooled
- mixture
- Prior art date
Links
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 claims description 3
- 238000004519 manufacturing process Methods 0.000 claims description 3
- 238000000034 method Methods 0.000 claims description 2
- 238000007363 ring formation reaction Methods 0.000 claims description 2
- 239000005864 Sulphur Substances 0.000 claims 1
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 6
- 238000002844 melting Methods 0.000 description 5
- 230000008018 melting Effects 0.000 description 5
- UHOVQNZJYSORNB-UHFFFAOYSA-N Benzene Chemical compound C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 description 3
- 239000000203 mixture Substances 0.000 description 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 2
- IMNFDUFMRHMDMM-UHFFFAOYSA-N N-Heptane Chemical compound CCCCCCC IMNFDUFMRHMDMM-UHFFFAOYSA-N 0.000 description 2
- 238000009835 boiling Methods 0.000 description 2
- 229910052717 sulfur Inorganic materials 0.000 description 2
- 239000011593 sulfur Substances 0.000 description 2
- WJFKNYWRSNBZNX-UHFFFAOYSA-N 10H-phenothiazine Chemical class C1=CC=C2NC3=CC=CC=C3SC2=C1 WJFKNYWRSNBZNX-UHFFFAOYSA-N 0.000 description 1
- 241001480043 Arthrodermataceae Species 0.000 description 1
- RWSOTUBLDIXVET-UHFFFAOYSA-N Dihydrogen sulfide Chemical compound S RWSOTUBLDIXVET-UHFFFAOYSA-N 0.000 description 1
- 239000003963 antioxidant agent Substances 0.000 description 1
- 230000003078 antioxidant effect Effects 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 239000013078 crystal Substances 0.000 description 1
- 238000006114 decarboxylation reaction Methods 0.000 description 1
- 230000037304 dermatophytes Effects 0.000 description 1
- 230000000855 fungicidal effect Effects 0.000 description 1
- 239000000417 fungicide Substances 0.000 description 1
- 239000003317 industrial substance Substances 0.000 description 1
- PNDPGZBMCMUPRI-UHFFFAOYSA-N iodine Chemical compound II PNDPGZBMCMUPRI-UHFFFAOYSA-N 0.000 description 1
- 239000000314 lubricant Substances 0.000 description 1
- 239000012299 nitrogen atmosphere Substances 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 238000000746 purification Methods 0.000 description 1
- 238000001953 recrystallisation Methods 0.000 description 1
- 238000004073 vulcanization Methods 0.000 description 1
Classifications
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F26—DRYING
- F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
- F26B21/00—Arrangements or duct systems, e.g. in combination with pallet boxes, for supplying and controlling air or gases for drying solid materials or objects
- F26B21/06—Controlling, e.g. regulating, parameters of gas supply
- F26B21/08—Humidity
- F26B21/083—Humidity by using sorbent or hygroscopic materials, e.g. chemical substances, molecular sieves
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D53/00—Separation of gases or vapours; Recovering vapours of volatile solvents from gases; Chemical or biological purification of waste gases, e.g. engine exhaust gases, smoke, fumes, flue gases, aerosols
- B01D53/02—Separation of gases or vapours; Recovering vapours of volatile solvents from gases; Chemical or biological purification of waste gases, e.g. engine exhaust gases, smoke, fumes, flue gases, aerosols by adsorption, e.g. preparative gas chromatography
-
- C—CHEMISTRY; METALLURGY
- C01—INORGANIC CHEMISTRY
- C01B—NON-METALLIC ELEMENTS; COMPOUNDS THEREOF; METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C
- C01B17/00—Sulfur; Compounds thereof
- C01B17/48—Sulfur dioxide; Sulfurous acid
- C01B17/50—Preparation of sulfur dioxide
- C01B17/56—Separation; Purification
-
- C—CHEMISTRY; METALLURGY
- C01—INORGANIC CHEMISTRY
- C01B—NON-METALLIC ELEMENTS; COMPOUNDS THEREOF; METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C
- C01B17/00—Sulfur; Compounds thereof
- C01B17/69—Sulfur trioxide; Sulfuric acid
- C01B17/74—Preparation
- C01B17/76—Preparation by contact processes
- C01B17/80—Apparatus
- C01B17/806—Absorbers; Heat exchangers
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Inorganic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Mechanical Engineering (AREA)
- General Engineering & Computer Science (AREA)
- Analytical Chemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Gas Separation By Absorption (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Treating Waste Gases (AREA)
- Drying Of Gases (AREA)
Description
Fremgangsmåte for fremstilling av 3-metyltiofentiazin.
Nærværende oppfinnelse angår en
fremgangsmåte for fremstilling av fentia-zinderivatet 3-metyltiofentiazin.
Ifølge oppfinnelsen fremstilles 3-metyltiofentiazin (Beilstein-nomenklatur), en
hittil ukjent forbindelse ved syklisering av
3-metyltiodifenylamin med svovel.
3-metyltiofentiazin er et viktig indu-strielt kjemikalium. Det kan brukes som
vulkaniseringsaksellerator, antioksydant
for smøremidler, som anthelmintica og som
fungicid, særlig mot dermatofyter. Det er
også verdifullt som mellomprodukt for
fremstilling av terapeutisk anvendelige N-aminoalkylfentiaziner.
Oppfinnelsen illustreres ved det føl-gende utførelseseksempel, i hvilket smelte-punktene som er angitt, er bestemt med
Koflerapparat.
Eksempel: 3-metyltiodifenylamin (539 g) blan-des intimt med svovel (160,4 g) og etter til-setting av noen få milligram jod, oppvar-mes blandingen til 175° C i 4 timer i nitro-genatmosfære og økes deretter gradvis i
løpet av 45 minutter til 225° C. Utvikling
av svovelvannstoff har hørt opp når denne
temperatur er nådd, og blandingen kjøles
til 150° C og helles i kokende metanol (2500 cm<*>). En uoppløselig olje skiller seg ut, oppløsningen kjøles til ca. 15° C og får henstå i 17 timer ved denne temperatur. Etter at den metanoliske oppløsning er de-kantert, konsentreres den under redusert trykk. Ca. 2200 cm<:1> metanol destilleres av, og innholdet av flasken kjøles derpå til 10° C og filtreres. Der oppnås slik gule krystal-ler (509 g), smeltepunkt 126° C.
Rensning kan utføres ved omkrystalli-sering fra etanol og fra en blanding av ben-zol og heptan. 3-metyltiofentiazin (230 g) oppnås tilslutt, smeltepunkt 136° C.
Utgangs 3-metyltiodifenylaminet (ko-kepunkt 160—186° C/0,12 mm Hg og smeltepunkt 58° C) oppnås ved dekarboksyle-ring av 2-karboksy-3'-metyltiodifenylamin, smeltepunkt 140—141° C.
Claims (1)
- Fremgangsmåte for fremstilling av 3-metyltiofentiazin (Beilstein-nomenklatur), karakterisert ved cyklisering av 3-metyltiodifenylamin med svovel.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE1968M0077146 DE1719559B2 (de) | 1968-02-03 | 1968-02-03 | Absorptionsvorrichtung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO127137B true NO127137B (no) | 1973-05-14 |
Family
ID=7317458
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO36369A NO127137B (no) | 1968-02-03 | 1969-01-30 |
Country Status (8)
| Country | Link |
|---|---|
| BE (1) | BE727810A (no) |
| CA (1) | CA926771A (no) |
| DE (1) | DE1719559B2 (no) |
| ES (1) | ES362642A1 (no) |
| NL (1) | NL6901613A (no) |
| NO (1) | NO127137B (no) |
| SE (1) | SE361826B (no) |
| YU (1) | YU32910B (no) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2740039A1 (de) * | 1977-09-06 | 1979-03-15 | Heinz Hoelter | 2-stufen-gaswaescher |
| FR2457456A1 (fr) * | 1979-05-23 | 1980-12-19 | Commissariat Energie Atomique | Procede de sechage de produits, notamment de produits agricoles, a l'aide du pouvoir calorifique du rayonnement solaire et dispositif pour la mise en oeuvre de ce procede |
| FI62002C (fi) * | 1981-04-15 | 1982-11-10 | Outokumpu Oy | Foerfarande och anordning foer separering av kvicksilver ur svveldioxidhaltiga heta och fuktiga gaser |
| FR2938448B1 (fr) * | 2008-11-20 | 2014-09-26 | Total Raffinage Marketing | Dispositif et procede pour le traitement et la compression des gaz |
| DE102008058637B4 (de) | 2008-11-22 | 2017-01-05 | Outotec Oyj | Abscheideeinrichtung |
-
1968
- 1968-02-03 DE DE1968M0077146 patent/DE1719559B2/de active Granted
- 1968-12-27 SE SE1788968A patent/SE361826B/xx unknown
-
1969
- 1969-01-17 ES ES362642A patent/ES362642A1/es not_active Expired
- 1969-01-30 NO NO36369A patent/NO127137B/no unknown
- 1969-01-30 CA CA041615A patent/CA926771A/en not_active Expired
- 1969-01-31 NL NL6901613A patent/NL6901613A/xx unknown
- 1969-01-31 BE BE727810D patent/BE727810A/xx unknown
- 1969-02-03 YU YU24669A patent/YU32910B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA926771A (en) | 1973-05-22 |
| BE727810A (no) | 1969-07-01 |
| DE1719559A1 (de) | 1972-02-24 |
| DE1719559B2 (de) | 1976-12-02 |
| SE361826B (no) | 1973-11-19 |
| NL6901613A (no) | 1969-08-05 |
| ES362642A1 (es) | 1970-11-16 |
| YU32910B (en) | 1975-10-31 |
| YU24669A (en) | 1975-04-30 |
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