NL950008I2 - Topische preparaten voor het verlagen van de intra-oculaire druk. - Google Patents
Topische preparaten voor het verlagen van de intra-oculaire druk.Info
- Publication number
- NL950008I2 NL950008I2 NL950008C NL950008C NL950008I2 NL 950008 I2 NL950008 I2 NL 950008I2 NL 950008 C NL950008 C NL 950008C NL 950008 C NL950008 C NL 950008C NL 950008 I2 NL950008 I2 NL 950008I2
- Authority
- NL
- Netherlands
- Prior art keywords
- intraocular pressure
- lowering intraocular
- topical preparations
- trisubstituted
- lowering
- Prior art date
Links
- 230000004410 intraocular pressure Effects 0.000 title abstract 2
- 230000000699 topical effect Effects 0.000 title abstract 2
- 238000002360 preparation method Methods 0.000 title 1
- -1 2-(trisubstituted phenylimino)-imidazole compounds Chemical class 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/44—Nitrogen atoms not forming part of a nitro radical
- C07D233/50—Nitrogen atoms not forming part of a nitro radical with carbocyclic radicals directly attached to said nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Ophthalmology & Optometry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Fertilizers (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US32336981A | 1981-11-20 | 1981-11-20 |
Publications (2)
Publication Number | Publication Date |
---|---|
NL950008I1 NL950008I1 (nl) | 1995-06-16 |
NL950008I2 true NL950008I2 (nl) | 1996-12-02 |
Family
ID=23258921
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NL950008C NL950008I2 (nl) | 1981-11-20 | 1995-05-08 | Topische preparaten voor het verlagen van de intra-oculaire druk. |
Country Status (6)
Country | Link |
---|---|
EP (1) | EP0081924B1 (enEXAMPLES) |
JP (1) | JPS58116417A (enEXAMPLES) |
AT (1) | ATE18006T1 (enEXAMPLES) |
CA (1) | CA1201066A (enEXAMPLES) |
DE (1) | DE3269242D1 (enEXAMPLES) |
NL (1) | NL950008I2 (enEXAMPLES) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2549049B1 (fr) * | 1983-07-13 | 1986-06-20 | Chauvin Blache Lab | Nouvelles amidines, leur procede de preparation et leur application therapeutique |
EP0236636A3 (en) * | 1986-02-07 | 1988-12-07 | Alcon Laboratories, Inc. | Use of clonidine derivatives for the preparation of ocular hemostatic agents |
FR2592042B1 (fr) * | 1985-12-19 | 1988-03-25 | Ile De France | Nouveaux ortho-anisamides, leur procede d'obtention, et leurs applications therapeutiques |
US4801617A (en) * | 1987-04-06 | 1989-01-31 | Leclerc Gerard | Iminoimidazolidines useful in lowering intraocular pressure |
US5304569A (en) * | 1989-11-13 | 1994-04-19 | Orion-Yhtyma Oy | Compositions and their use in lowering intraocular pressure |
US5124154A (en) * | 1990-06-12 | 1992-06-23 | Insite Vision Incorporated | Aminosteroids for ophthalmic use |
US5340572A (en) * | 1993-02-08 | 1994-08-23 | Insite Vision Incorporated | Alkaline ophthalmic suspensions |
DE19514579A1 (de) | 1995-04-20 | 1996-10-24 | Boehringer Ingelheim Kg | Verwendung von alpha¶1¶¶L¶-Agonisten zur Behandlung der Harninkontinenz |
US6602897B2 (en) | 2000-10-14 | 2003-08-05 | Boehringer Ingelheim Pharma Kg | m-Amino-phenylimino-imidazolidine derivatives for treating urinary incontinence |
IL155338A0 (en) * | 2000-10-14 | 2003-11-23 | Boehringer Ingelheim Pharma | Novel m-amino-phenylimino-imidazolidine derivatives for treating urinary incontinence |
CN100335053C (zh) * | 2005-02-18 | 2007-09-05 | 山东鲁抗辰欣药业有限公司 | 一种药物制剂及其制备方法 |
GB2466622A (en) * | 2008-12-23 | 2010-06-30 | Trinity College Dublin | Alpha2-Adrenoceptor Ligands |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3636219A (en) * | 1964-03-02 | 1972-01-18 | Du Pont | Anticholinergic compositions containing certain thiazolines or imidazolines |
DE1670274A1 (de) * | 1966-10-31 | 1970-07-16 | Boehringer Sohn Ingelheim | Neues Verfahren zur Herstellung von 2-Arylamino-1,3-diazacycloalkenen-(2) |
AT285599B (de) * | 1968-06-21 | 1970-11-10 | Boehringer Sohn Ingelheim | Verfahren zur Herstellung von neuen trisubstituierten 2-Arylaminoimidazolinen und ihren Salzen |
BE759125A (fr) * | 1969-11-19 | 1971-05-18 | Boehringer Sohn Ingelheim | Nouvelles n-allyl-2-arylamino-imidazolines-(2) substituees et procedes pour les fabriquer |
BE759126A (fr) * | 1969-11-19 | 1971-05-18 | Boehringer Sohn Ingelheim | Nouvelles n-cycloalcoyl-arylamino-imidazolines-(2) substituees et procedes pour les fabriquer |
GB1595412A (en) * | 1976-12-14 | 1981-08-12 | Boots Co Ltd | Method for control of pests attacking animals |
DE2806811A1 (de) * | 1978-02-17 | 1979-08-23 | Boehringer Sohn Ingelheim | Neue substituierte 2-phenylimino- imidazolidine, deren saeureadditionssalze, diese enthaltene arzneimittel und verfahren zur herstellung derselben |
DE2806775A1 (de) * | 1978-02-17 | 1979-08-30 | Boehringer Sohn Ingelheim | Neue substituierte 2-phenylimino- imidazolidine deren saeureadditionssalze, diese enthaltende arzneimittel und verfahren zur herstellung derselben |
US4287201A (en) * | 1980-03-03 | 1981-09-01 | Merck & Co., Inc. | Anovulatory method and chicken feed compositions |
EP0043659B1 (en) * | 1980-07-09 | 1985-02-06 | Beecham Group Plc | Clonidine derivatives useful in the treatment of diarrhoea |
-
1982
- 1982-11-09 CA CA000415190A patent/CA1201066A/en not_active Expired
- 1982-11-19 AT AT82306188T patent/ATE18006T1/de active
- 1982-11-19 DE DE8282306188T patent/DE3269242D1/de not_active Expired
- 1982-11-19 EP EP82306188A patent/EP0081924B1/en not_active Expired
- 1982-11-20 JP JP57204428A patent/JPS58116417A/ja active Granted
-
1995
- 1995-05-08 NL NL950008C patent/NL950008I2/nl unknown
Also Published As
Publication number | Publication date |
---|---|
CA1201066A (en) | 1986-02-25 |
EP0081924B1 (en) | 1986-02-19 |
DE3269242D1 (en) | 1986-03-27 |
ATE18006T1 (de) | 1986-03-15 |
EP0081924A1 (en) | 1983-06-22 |
JPS58116417A (ja) | 1983-07-11 |
JPH0453846B2 (enEXAMPLES) | 1992-08-27 |
NL950008I1 (nl) | 1995-06-16 |
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