ATE18006T1 - Lokale zusammensetzungen zur reduktion intraokularen druckes. - Google Patents

Lokale zusammensetzungen zur reduktion intraokularen druckes.

Info

Publication number
ATE18006T1
ATE18006T1 AT82306188T AT82306188T ATE18006T1 AT E18006 T1 ATE18006 T1 AT E18006T1 AT 82306188 T AT82306188 T AT 82306188T AT 82306188 T AT82306188 T AT 82306188T AT E18006 T1 ATE18006 T1 AT E18006T1
Authority
AT
Austria
Prior art keywords
intraocular pressure
reducing intraocular
local compositions
compositions
local
Prior art date
Application number
AT82306188T
Other languages
German (de)
English (en)
Inventor
Billie Murray York Jr
Icilio Cavero
Salomon Z Langer
Original Assignee
Alcon Lab Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alcon Lab Inc filed Critical Alcon Lab Inc
Application granted granted Critical
Publication of ATE18006T1 publication Critical patent/ATE18006T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/44—Nitrogen atoms not forming part of a nitro radical
    • C07D233/50—Nitrogen atoms not forming part of a nitro radical with carbocyclic radicals directly attached to said nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Ophthalmology & Optometry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Fertilizers (AREA)
AT82306188T 1981-11-20 1982-11-19 Lokale zusammensetzungen zur reduktion intraokularen druckes. ATE18006T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US32336981A 1981-11-20 1981-11-20
EP82306188A EP0081924B1 (en) 1981-11-20 1982-11-19 Topical compostions for lowering intraocular pressure

Publications (1)

Publication Number Publication Date
ATE18006T1 true ATE18006T1 (de) 1986-03-15

Family

ID=23258921

Family Applications (1)

Application Number Title Priority Date Filing Date
AT82306188T ATE18006T1 (de) 1981-11-20 1982-11-19 Lokale zusammensetzungen zur reduktion intraokularen druckes.

Country Status (6)

Country Link
EP (1) EP0081924B1 (enEXAMPLES)
JP (1) JPS58116417A (enEXAMPLES)
AT (1) ATE18006T1 (enEXAMPLES)
CA (1) CA1201066A (enEXAMPLES)
DE (1) DE3269242D1 (enEXAMPLES)
NL (1) NL950008I2 (enEXAMPLES)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2549049B1 (fr) * 1983-07-13 1986-06-20 Chauvin Blache Lab Nouvelles amidines, leur procede de preparation et leur application therapeutique
EP0236636A3 (en) * 1986-02-07 1988-12-07 Alcon Laboratories, Inc. Use of clonidine derivatives for the preparation of ocular hemostatic agents
FR2592042B1 (fr) * 1985-12-19 1988-03-25 Ile De France Nouveaux ortho-anisamides, leur procede d'obtention, et leurs applications therapeutiques
US4801617A (en) * 1987-04-06 1989-01-31 Leclerc Gerard Iminoimidazolidines useful in lowering intraocular pressure
US5304569A (en) * 1989-11-13 1994-04-19 Orion-Yhtyma Oy Compositions and their use in lowering intraocular pressure
US5124154A (en) * 1990-06-12 1992-06-23 Insite Vision Incorporated Aminosteroids for ophthalmic use
US5340572A (en) * 1993-02-08 1994-08-23 Insite Vision Incorporated Alkaline ophthalmic suspensions
DE19514579A1 (de) 1995-04-20 1996-10-24 Boehringer Ingelheim Kg Verwendung von alpha¶1¶¶L¶-Agonisten zur Behandlung der Harninkontinenz
US6602897B2 (en) 2000-10-14 2003-08-05 Boehringer Ingelheim Pharma Kg m-Amino-phenylimino-imidazolidine derivatives for treating urinary incontinence
IL155338A0 (en) * 2000-10-14 2003-11-23 Boehringer Ingelheim Pharma Novel m-amino-phenylimino-imidazolidine derivatives for treating urinary incontinence
CN100335053C (zh) * 2005-02-18 2007-09-05 山东鲁抗辰欣药业有限公司 一种药物制剂及其制备方法
GB2466622A (en) * 2008-12-23 2010-06-30 Trinity College Dublin Alpha2-Adrenoceptor Ligands

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3636219A (en) * 1964-03-02 1972-01-18 Du Pont Anticholinergic compositions containing certain thiazolines or imidazolines
DE1670274A1 (de) * 1966-10-31 1970-07-16 Boehringer Sohn Ingelheim Neues Verfahren zur Herstellung von 2-Arylamino-1,3-diazacycloalkenen-(2)
AT285599B (de) * 1968-06-21 1970-11-10 Boehringer Sohn Ingelheim Verfahren zur Herstellung von neuen trisubstituierten 2-Arylaminoimidazolinen und ihren Salzen
BE759125A (fr) * 1969-11-19 1971-05-18 Boehringer Sohn Ingelheim Nouvelles n-allyl-2-arylamino-imidazolines-(2) substituees et procedes pour les fabriquer
BE759126A (fr) * 1969-11-19 1971-05-18 Boehringer Sohn Ingelheim Nouvelles n-cycloalcoyl-arylamino-imidazolines-(2) substituees et procedes pour les fabriquer
GB1595412A (en) * 1976-12-14 1981-08-12 Boots Co Ltd Method for control of pests attacking animals
DE2806811A1 (de) * 1978-02-17 1979-08-23 Boehringer Sohn Ingelheim Neue substituierte 2-phenylimino- imidazolidine, deren saeureadditionssalze, diese enthaltene arzneimittel und verfahren zur herstellung derselben
DE2806775A1 (de) * 1978-02-17 1979-08-30 Boehringer Sohn Ingelheim Neue substituierte 2-phenylimino- imidazolidine deren saeureadditionssalze, diese enthaltende arzneimittel und verfahren zur herstellung derselben
US4287201A (en) * 1980-03-03 1981-09-01 Merck & Co., Inc. Anovulatory method and chicken feed compositions
EP0043659B1 (en) * 1980-07-09 1985-02-06 Beecham Group Plc Clonidine derivatives useful in the treatment of diarrhoea

Also Published As

Publication number Publication date
CA1201066A (en) 1986-02-25
EP0081924B1 (en) 1986-02-19
DE3269242D1 (en) 1986-03-27
NL950008I2 (nl) 1996-12-02
EP0081924A1 (en) 1983-06-22
JPS58116417A (ja) 1983-07-11
JPH0453846B2 (enEXAMPLES) 1992-08-27
NL950008I1 (nl) 1995-06-16

Similar Documents

Publication Publication Date Title
EG15458A (en) Improvements in or relating to 3-aryloxy-3-phenylpropylamines
ATE52495T1 (de) 2-(2'-nitrobenzoyl)-1,3-cyclohexandionen.
DE3674569D1 (de) 2-((3,5-dihalo-4-aminobenzyl))imidazole.
FI854592L (fi) Fungicida azolfoereningar.
JPS5756480A (en) Novel substituted pyradinyl-1,2,4- oxadiazol-5-one and manufacture
DE3275184D1 (de) 2-(trisubstituted phenylimino)-imidazolines
SE8600174L (sv) Nytt forfarande for framstellning av n-(2-pyrimidinyl)-piperazinylalkylazaspiroalkandioner
ATE18006T1 (de) Lokale zusammensetzungen zur reduktion intraokularen druckes.
BG42185A3 (en) Method for preparing pyridylic compounds
BG40147A3 (bg) Метод за получаване на хетероциклични съединения
DE3770361D1 (de) Azolderivate, geeignet zur bekaempfung von pflanzen-krankheiten.
BG38940A3 (en) Method for preparing penicillanoyloxymethyl penicillanate- 1, 1- dioxide
GR3002981T3 (en) 1-((2-fluorophenyl)(4-fluorophenyl)phenylmethyl)-1h-imidazole
DE3264578D1 (en) Thio-substituted-1,3,5-triazine-diamines and -triamines useful as prevulcanization inhibitors
MA21041A1 (fr) Derive d'imidazole .
IT8120307A0 (it) Disposizione per il trattamento termico di pezzi d'opera.
AU546890B2 (en) 4-aminomethyl-5-acyl-1,3 dihydro-2h-imidazol-2-ones
IT8024353A0 (it) Procedimento per la preparazione di 2,5-dimetil 2,4-esadiene.
BG41127A3 (en) Method for preparing 1, 4- dihydropyridine derivatives
ES512696A0 (es) "procedimiento de obtener compuestos metilquinoxalin-1,4-dioxidicos".
IE821041L (en) Imidazolones
BG40811A3 (en) Method for preparing 2- metoxyethyl- 4- hydroxy- 2- methyl- 2h- 1, 2- benzothiazine- 3- carboxylate- 1, 1- dioxide
DK464982A (da) Fremgangsmaade til fremstilling af 1-(2,4-dichlorphenoxy)-3-(3,4-dimethoxy-beta-phenethylamino)-propanol-(2)
IT8024108A0 (it) Derivati del2-solfinil-5-solfonil-1,3,4-tiadiazolo, procedimento per la fabbricazione di questi composti nonche' mezzi fungicidi che licontengono.
KR850003309A (ko) 5-치환된 옥사졸리딘 2, 4-디온의 제조 방법