NL8203482A - Cefalosporine-chinolinium-betainen. - Google Patents

Cefalosporine-chinolinium-betainen. Download PDF

Info

Publication number
NL8203482A
NL8203482A NL8203482A NL8203482A NL8203482A NL 8203482 A NL8203482 A NL 8203482A NL 8203482 A NL8203482 A NL 8203482A NL 8203482 A NL8203482 A NL 8203482A NL 8203482 A NL8203482 A NL 8203482A
Authority
NL
Netherlands
Prior art keywords
group
formula
amino
alkyl
substituted
Prior art date
Application number
NL8203482A
Other languages
English (en)
Dutch (nl)
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of NL8203482A publication Critical patent/NL8203482A/nl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/38—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
    • C07D501/46—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof with the 7-amino radical acylated by carboxylic acids containing hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NL8203482A 1981-09-08 1982-09-07 Cefalosporine-chinolinium-betainen. NL8203482A (nl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US30013181 1981-09-08
US06/300,131 US4396620A (en) 1981-09-08 1981-09-08 Cephalosporin quinolinium betaines

Publications (1)

Publication Number Publication Date
NL8203482A true NL8203482A (nl) 1983-04-05

Family

ID=23157840

Family Applications (1)

Application Number Title Priority Date Filing Date
NL8203482A NL8203482A (nl) 1981-09-08 1982-09-07 Cefalosporine-chinolinium-betainen.

Country Status (11)

Country Link
US (1) US4396620A (fr)
JP (1) JPS5857387A (fr)
AU (1) AU550341B2 (fr)
BE (1) BE894334A (fr)
DE (1) DE3233376A1 (fr)
FR (1) FR2512449B1 (fr)
GB (1) GB2105335B (fr)
IL (1) IL66811A0 (fr)
IT (1) IT1158050B (fr)
NL (1) NL8203482A (fr)
ZA (1) ZA826540B (fr)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1582884A (en) * 1977-05-19 1981-01-14 Beecham Group Ltd Clavulanic acid derivatives their preparation and use
DK330880A (da) * 1979-08-03 1981-02-04 Beecham Group Ltd Fremgangsmaade til fremstilling af clavulansyrederivater
DE3169452D1 (en) * 1980-12-09 1985-04-25 Beecham Group Plc Derivatives of clavulanic acid, their preparation and their use
US4562182A (en) * 1980-12-23 1985-12-31 Beecham Group P.L.C. Compounds containing beta-lactams
DE3207840A1 (de) * 1982-03-04 1983-09-15 Hoechst Ag, 6230 Frankfurt "cephalosporinderivate und verfahren zu ihrer herstellung"
DE3247614A1 (de) * 1982-12-23 1984-07-05 Hoechst Ag, 6230 Frankfurt Cephalosporinderivate und verfahren zu ihrer herstellung
DE3316797A1 (de) * 1983-05-07 1984-11-08 Hoechst Ag, 6230 Frankfurt Verfahren zur herstellung von cephemverbindungen
DE3316798A1 (de) * 1983-05-07 1984-11-08 Hoechst Ag, 6230 Frankfurt Verfahren zur herstellung von cephemverbindungen
EP0137442A3 (fr) * 1983-10-08 1986-01-15 Hoechst Aktiengesellschaft Dérivés de céphalosporine et procédé pour leur préparation
GB8401093D0 (en) * 1984-01-16 1984-02-15 Fujisawa Pharmaceutical Co Cephem compounds
DE3419012A1 (de) * 1984-05-22 1985-11-28 Bayer Ag, 5090 Leverkusen Ss-lactamantibiotika, verfahren zu deren herstellung sowie ihre verwendung als arzneimittel oder wachstumsfoerderer in der tieraufzucht oder als antioxidantien
EP0204781B1 (fr) * 1984-11-23 1995-04-26 BIOCHEMIE Gesellschaft m.b.H. Procede pour la preparation de derives de 3-iodo-methylcephalosporines bissilyles
DE3585434D1 (de) * 1984-12-27 1992-04-02 Banyu Pharma Co Ltd Cephalosporinverbindungen.
ATE89826T1 (de) * 1985-03-01 1993-06-15 Takeda Chemical Industries Ltd Antibakterielle verbindungen, ihre herstellung und verwendung.
US4703118A (en) * 1985-04-08 1987-10-27 Eli Lilly And Company Synthesis of 3-iodomethyl cephalosporins
US4749522A (en) * 1985-10-31 1988-06-07 Angio-Medical Corporation Supercritical fluid extraction of animal derived materials
US4814328A (en) * 1986-03-19 1989-03-21 Banyu Pharmaceutical Co., Ltd. Cephalosporin derivatives, and antibacterial agents
US5147871A (en) * 1986-07-03 1992-09-15 Hoffmann La-Roche, Inc. Anti-bacterial cephalosporin compounds
NZ227470A (en) * 1987-12-28 1991-06-25 Hoffmann La Roche Acyl derivatives of substituted cephem compounds; pharmaceutical compositions and methods for preparation and treatment
US5019571A (en) * 1988-01-25 1991-05-28 Eli Lilly And Company 1-carbacephalosporin antibiotics
DE3910421A1 (de) * 1989-03-31 1990-10-04 Hoechst Ag Polare cephalosporinderivate und verfahren zu ihrer herstellung
US5159077A (en) * 1989-07-21 1992-10-27 Hoffmann-La Roche Inc. Penam antibacterial compounds
US5162523A (en) * 1989-07-21 1992-11-10 Hoffmann-La Roche Inc. Cephalosporin antibacterial compounds
FR2873695A1 (fr) * 2004-07-30 2006-02-03 Palumed Sa Molecules hybrides qa ou q est une aminoquinoleine et a est un antibiotique ou un inhibiteur de resistance), leur synthese et leurs utilisations en tant qu'agent antibacterien

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE786271A (fr) * 1971-07-17 1973-01-15 Takeda Chemical Industries Ltd Cephalosporines
US4160830A (en) * 1971-07-17 1979-07-10 Takeda Chemical Industries, Ltd. Cephalosporins
DK154939C (da) * 1974-12-19 1989-06-12 Takeda Chemical Industries Ltd Analogifremgangsmaade til fremstilling af thiazolylacetamido-cephemforbindelser eller farmaceutisk acceptable salte eller estere deraf
DE2760123C2 (de) * 1976-01-23 1986-04-30 Roussel-Uclaf, Paris 7-Aminothiazolyl-syn-oxyiminoacetamidocephalosporansäuren, ihre Herstellung und sie enthaltende pharmazeutische Zusammensetzungen
DE2760484C2 (fr) * 1976-04-14 1992-12-03 Takeda Chemical Industries, Ltd., Osaka, Jp
JPS6011713B2 (ja) * 1976-09-08 1985-03-27 武田薬品工業株式会社 セフアロスポリン誘導体およびその製造法
DE2714880A1 (de) * 1977-04-02 1978-10-26 Hoechst Ag Cephemderivate und verfahren zu ihrer herstellung
JPS609719B2 (ja) * 1977-08-06 1985-03-12 武田薬品工業株式会社 セフアロスポリン誘導体およびその製造法
FR2410655A1 (fr) * 1977-12-05 1979-06-29 Roussel Uclaf Nouvelles oximes derivees de l'acide 3-substitue 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments

Also Published As

Publication number Publication date
ZA826540B (en) 1984-04-25
GB2105335B (en) 1985-05-15
JPS5857387A (ja) 1983-04-05
AU8809082A (en) 1983-03-17
US4396620A (en) 1983-08-02
GB2105335A (en) 1983-03-23
IT8223152A0 (it) 1982-09-07
IT1158050B (it) 1987-02-18
BE894334A (fr) 1983-03-07
FR2512449B1 (fr) 1986-04-18
DE3233376A1 (de) 1983-03-24
AU550341B2 (en) 1986-03-20
FR2512449A1 (fr) 1983-03-11
IL66811A0 (en) 1982-12-31

Similar Documents

Publication Publication Date Title
NL8203482A (nl) Cefalosporine-chinolinium-betainen.
US4396619A (en) Cephalosporin betaines
KR900005047B1 (ko) 세팔로스포린 유도체의 제조방법
US4402955A (en) Dioximino cephalosporin antibiotics
JPH05502884A (ja) 新規３―置換セフェム化合物及びその製造方法
CA1225390A (fr) Cephalosporines 3-bicyclopyridinium-methyliques
US4692443A (en) 3-bicyclicpyridinium-methyl cephalosporins
CS232735B2 (en) Method of making cephalosporine derivatives
US4785090A (en) Cephalosporin derivatives
US5202315A (en) Cephalosporin compounds
US4501739A (en) Thieno and furopyridinium-substituted cephalosporins
DE3854684T2 (de) Cephalosporinverbindungen, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Präparate.
US4748172A (en) 3-bicyclicpyridinium-methyl cephalosporins
IE54050B1 (en) Pyrazinium substituted cephalosporins
US4382932A (en) Isoquinolinium substituted cephalosporins
US4577014A (en) Thieno and furopyridinium-substituted cephalosporins
EP0137442A2 (fr) Dérivés de céphalosporine et procédé pour leur préparation
US4450270A (en) Dioximino cephalosporin antibiotics
US4382931A (en) 3'-Substituted quinolinium cephalosporins
JPS5857390A (ja) チエノ−およびフロ−ピリジニウム置換セフアロスポリン誘導体
EP0193858B1 (fr) Dérivés de 1-oxa-1-déthia-céphalosporine et agent antibactérien les contenant
JPS62158282A (ja) １−カルバセフアロスポリン抗生物質
KR0154901B1 (ko) 신규 세팔로스포린계 항생제(v)
JPH04266889A (ja) 抗生物質ｃ−３カテコ−ル−置換セファロスボリン化合物、組成物およびその使用法
US4857521A (en) Trialkylsilyl pyridinium cephalosporin antibiotics

Legal Events

Date Code Title Description
A85 Still pending on 85-01-01
BV The patent application has lapsed