NL7902333A - 3-acetoxy-9beta,11beta-epoxy-trienen en -dienen en de bereiding van de overeenkomstige 6alpha-halogeen-1,4- -dieen-3-onen en 6alpha-halogeen-4-een-3-onen. - Google Patents
3-acetoxy-9beta,11beta-epoxy-trienen en -dienen en de bereiding van de overeenkomstige 6alpha-halogeen-1,4- -dieen-3-onen en 6alpha-halogeen-4-een-3-onen.Info
- Publication number
- NL7902333A NL7902333A NL7902333A NL7902333A NL7902333A NL 7902333 A NL7902333 A NL 7902333A NL 7902333 A NL7902333 A NL 7902333A NL 7902333 A NL7902333 A NL 7902333A NL 7902333 A NL7902333 A NL 7902333A
- Authority
- NL
- Netherlands
- Prior art keywords
- 6alpha
- ones
- halogen
- 9beta
- 11beta
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C07J71/0005—Oxygen-containing hetero ring
- C07J71/0026—Oxygen-containing hetero ring cyclic ketals
- C07J71/0031—Oxygen-containing hetero ring cyclic ketals at positions 16, 17
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C07J71/0005—Oxygen-containing hetero ring
- C07J71/001—Oxiranes
- C07J71/0015—Oxiranes at position 9(11)
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Steroid Compounds (AREA)
- Epoxy Compounds (AREA)
Priority Applications (12)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
NLAANVRAGE7902333,A NL187577C (nl) | 1978-04-05 | 1979-03-23 | 3-acetoxy-9beta,11beta-epoxy-pregna-1,3,5-trienen, werkwijze voor de bereiding daarvan en werkwijze voor de bereiding van 6alfa-halogeen-pregna-1,4-dieen-3-onen. |
DE19792913147 DE2913147A1 (de) | 1978-04-05 | 1979-04-02 | 3-acetoxy-9 beta , 11 beta -oxido- pregna-1,3,5-triene und -3,5-diene, verfahren zu deren herstellung und deren umwandlung in 6 alpha -halogen-1,4-pregna- dien-3-one und -4-pregnen-3-one |
US06/026,677 US4255331A (en) | 1978-04-05 | 1979-04-03 | 3-Acetoxy-9β-11β-epoxy-dienes and the preparation of the corresponding 6α-halogen-4-ene-3-ones |
GB7911796A GB2018258B (en) | 1978-04-05 | 1979-04-04 | 3 acetoxy & 11 epoxy pregna 3,5 dienes and 1,3,5 trienes and their use in the synthesis of 6 halocorticoids |
CH314779A CH639655A5 (de) | 1978-04-05 | 1979-04-04 | 3-acetoxy-9beta,11beta-oxido-pregna-1,3,5-triene und -3,5-diene. |
FR7910137A FR2421914A1 (fr) | 1978-04-05 | 1979-04-05 | 3-acetoxy-9b-11b-epoxy-pregna-trienes et dienes et procede de preparation de 6a-halogeno-pregna-1,4-diene-3 ones et de 6a halogeno-pregna-4-ene-3-ones correspondants |
PH22354A PH16138A (en) | 1978-04-05 | 1979-04-05 | Process for the preparation of 6-alpha-halo-substituted-pregna-4-ene-3 ones and pregna-1,4-diene-3-ones |
FI791124A FI66395C (fi) | 1978-04-05 | 1979-04-05 | 3-acetoxi-9alfa 11beta-epoxipregna-1,3,5-triener och motsvarande 3,5-diener anvaendbara som mellanprodukt vid framstaellning av 6alfa-halogen substituerade pregna-1,4-dien-3-oner ochpregn-4-en-3-oner och ett foerfarande foer framstaellning a dessa mellanprodukter |
AU46070/79A AU532142B2 (en) | 1979-03-23 | 1979-04-12 | 3-acetoxy-9beta, 11beta-epoxy trienes and -dienes and the preparation of the corresponding 6alpha-halogen-1,4-dienes- 3-ones and 6alpha-halogen-4-ene-3-ones |
IT7925149A IT1207228B (it) | 1979-03-23 | 1979-08-17 | 3-acetossi-9 beta, 11 beta -epossi-pregna-1, 3, 5-trieni emetodo per la loro conversione diretta nei corrispondenti 6 alfa-fluoro-1, 4-dien-3-oni. |
IT26227/79A IT1125437B (it) | 1979-03-23 | 1979-10-03 | 9 beta,11 beta-epossi-pregna-3,5-dieni e metodo per la loro trasformazione nei corrispondenti 6 alfa-alogeno-4-en-3-oni e 6 alfa-alogeno-1,4-deine-3-oni |
JP63141437A JPS6425793A (en) | 1978-04-05 | 1988-06-08 | Production of 3-acetoxy-9beta, 11beta-epoxypregna-1, 3, 5-trienes and 3, 5-dienes corresponding thereto |
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
NL7803655 | 1978-04-05 | ||
NL7803656 | 1978-04-05 | ||
NLAANVRAGE7902333,A NL187577C (nl) | 1978-04-05 | 1979-03-23 | 3-acetoxy-9beta,11beta-epoxy-pregna-1,3,5-trienen, werkwijze voor de bereiding daarvan en werkwijze voor de bereiding van 6alfa-halogeen-pregna-1,4-dieen-3-onen. |
Publications (3)
Publication Number | Publication Date |
---|---|
NL7902333A true NL7902333A (nl) | 1979-10-09 |
NL187577B NL187577B (nl) | 1991-06-17 |
NL187577C NL187577C (nl) | 1991-11-18 |
Family
ID=27352047
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NLAANVRAGE7902333,A NL187577C (nl) | 1978-04-05 | 1979-03-23 | 3-acetoxy-9beta,11beta-epoxy-pregna-1,3,5-trienen, werkwijze voor de bereiding daarvan en werkwijze voor de bereiding van 6alfa-halogeen-pregna-1,4-dieen-3-onen. |
Country Status (9)
Country | Link |
---|---|
US (1) | US4255331A (nl) |
JP (1) | JPS6425793A (nl) |
CH (1) | CH639655A5 (nl) |
DE (1) | DE2913147A1 (nl) |
FI (1) | FI66395C (nl) |
FR (1) | FR2421914A1 (nl) |
GB (1) | GB2018258B (nl) |
NL (1) | NL187577C (nl) |
PH (1) | PH16138A (nl) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4358445A (en) | 1979-11-16 | 1982-11-09 | Macdonald Peter | 6α-Fluoro-prednisdone 17,21 diesters |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4188322A (en) * | 1978-04-28 | 1980-02-12 | Blasinachim S.P.A. | Process for the preparation of 6-halo-pregnanes |
HU182775B (en) * | 1981-10-15 | 1984-03-28 | Richter Gedeon Vegyeszet | Process for preparing new 3-chloro-pregnane derivatives |
FR2701262B1 (fr) * | 1993-02-05 | 1995-03-24 | Roussel Uclaf | Nouveau procédé de préparation de stéroïdes 6 alpa, 9 alpha-difluorés et nouveaus intermédiaires. |
GB0017988D0 (en) * | 2000-07-21 | 2000-09-13 | Glaxo Group Ltd | Novel process |
IT1319663B1 (it) * | 2000-11-17 | 2003-10-23 | Farmabios Srl | Processo per la preparazione di fluoro-steroidi. |
PT102628B (pt) * | 2001-06-12 | 2010-09-09 | Hovione Farmaciencia S A | Novo processo de preparação de flumetasona e do seu análogo 17-carboxilo androsteno |
EP1275656A1 (en) * | 2001-07-11 | 2003-01-15 | Genchem Pharma Limited | Preparation of 9alpha-fluoro-11beta-hydroxypregnane 16,17-acetal derivatives |
IL162140A0 (en) * | 2001-11-29 | 2005-11-20 | Taro Pharmaceuticals Usa Inc | Method for the preparation of l-alpha-fluoro corticosteroids |
DE60303687D1 (de) * | 2002-12-09 | 2006-04-27 | Sicor Inc | Prozess zur herstellung von 6 alpa-fluorierten pregnanen |
CA2805832A1 (en) | 2010-07-20 | 2012-01-26 | Taro Pharmaceutical Industries Ltd. | Process for the preparation of 17-desoxy-corticosteroids |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
LU75903A1 (nl) * | 1976-09-29 | 1978-05-16 | ||
US3047596A (en) * | 1959-11-17 | 1962-07-31 | Merck & Co Inc | 6alpha-halogen-9alpha-halogen-delta-pregnadiene-3-one compounds |
SE339685B (nl) * | 1967-06-16 | 1971-10-18 | Warner Lambert Pharmaceutical | |
GB1403962A (en) * | 1972-03-09 | 1975-08-28 | Upjohn Co | Anti-inflammatory pregnane derivative |
US4188322A (en) * | 1978-04-28 | 1980-02-12 | Blasinachim S.P.A. | Process for the preparation of 6-halo-pregnanes |
-
1979
- 1979-03-23 NL NLAANVRAGE7902333,A patent/NL187577C/nl not_active IP Right Cessation
- 1979-04-02 DE DE19792913147 patent/DE2913147A1/de active Granted
- 1979-04-03 US US06/026,677 patent/US4255331A/en not_active Expired - Lifetime
- 1979-04-04 GB GB7911796A patent/GB2018258B/en not_active Expired
- 1979-04-04 CH CH314779A patent/CH639655A5/de not_active IP Right Cessation
- 1979-04-05 PH PH22354A patent/PH16138A/en unknown
- 1979-04-05 FI FI791124A patent/FI66395C/fi not_active IP Right Cessation
- 1979-04-05 FR FR7910137A patent/FR2421914A1/fr active Granted
-
1988
- 1988-06-08 JP JP63141437A patent/JPS6425793A/ja active Granted
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4358445A (en) | 1979-11-16 | 1982-11-09 | Macdonald Peter | 6α-Fluoro-prednisdone 17,21 diesters |
Also Published As
Publication number | Publication date |
---|---|
JPS6425793A (en) | 1989-01-27 |
CH639655A5 (de) | 1983-11-30 |
US4255331A (en) | 1981-03-10 |
FI66395B (fi) | 1984-06-29 |
FR2421914B1 (nl) | 1983-07-22 |
NL187577C (nl) | 1991-11-18 |
DE2913147C2 (nl) | 1988-06-30 |
FI791124A (fi) | 1979-10-06 |
PH16138A (en) | 1983-07-08 |
JPH0217560B2 (nl) | 1990-04-20 |
FR2421914A1 (fr) | 1979-11-02 |
GB2018258A (en) | 1979-10-17 |
NL187577B (nl) | 1991-06-17 |
DE2913147A1 (de) | 1979-10-18 |
FI66395C (fi) | 1984-10-10 |
GB2018258B (en) | 1983-02-02 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
A85 | Still pending on 85-01-01 | ||
BA | A request for search or an international-type search has been filed | ||
BB | A search report has been drawn up | ||
BC | A request for examination has been filed | ||
CNR | Transfer of rights (patent application after its laying open for public inspection) |
Free format text: SICOR S.P.A. |
|
CNR | Transfer of rights (patent application after its laying open for public inspection) |
Free format text: SIBLA S.R.L. |
|
TNT | Modifications of names of proprietors of patents or applicants of examined patent applications |
Owner name: ZANONI PHARMACEUTICALS S.R.L. |
|
V1 | Lapsed because of non-payment of the annual fee |
Effective date: 19981001 |